Clinical trials: Emergency Departments
Frailty, Frailty Syndrome
Loss of Independence - a Rapid Alternative to Frailty Screening in a Swedish ED Setting
This prospective observational study will investigate the correlation of a surrogate marker of frailty in relation to serious outcomes.
- Conditions
- Frailty, Frailty Syndrome, Emergency Department, Geriatric Assessment
- Trial name
- NCT04888884
- Where
- 3 sites in Sweden
- Volunteers
- 1,800 people
- Sponsor
- University Hospital, Linkoeping
Healthy Volunteers
Screening for Frailty at Home
"Many tools to evaluate frailty have been developed. However, at the time our study was designed, none of these instruments had been validated in terms of psychometric properties.
- Trial name
- SEGAm (NCT02852200)
- Testing
- SEGAm
- Where
- France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Communication Research
Evaluating AI for the Translation of KM Resources
Knowledge mobilization resources for parents provide information to help make health decisions for their children. These resources can include videos, infographics, and plain language summaries. They are often created in English.
- Trial name
- NCT07666399
- Testing
- KM Resource - English, KM Resource - Professionally Translated, KM Resouce - AI
- Where
- Canada
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Borderline Personality Disorder, Suicide and Self-harm
Trial of a Brief Psychological Intervention for Suicidal Patients with Borderline Personality Disorder in the Emergency Department
When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour.
- Trial name
- NCT04779099
- Testing
- Brief 4-session intervention for borderline personality disorder, Treatment as usual
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health
Conscious Sedation, Simple Lacerations Less Than 4 cm
A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department
The objective of this project is to compare the sedative effects of intranasal midazolam versus inhaled nitrous oxide (N2O) for minor procedures in the pediatric emergency department.
- Conditions
- Conscious Sedation, Simple Lacerations Less Than 4 cm, Lumbar Punctures, Minor Incision Drainage of Abscesses Not Requiring Extensive Debridement
- Trial name
- NCT03085563
- Testing
- Nitrous Oxide, Midazolam
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Colorado, Denver
Colorectal Cancer
Promoting Colorectal Cancer Screening in Rural Emergency Departments
This trial will compare the effects of a culturally targeted intervention designed to assist participants to identify and overcome individual barriers to colorectal cancer (CRC) and to promote CRC screenings using motivational…
- Trial name
- NCT03473587
- Testing
- Motivational interview, Standard of care
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Oncology
The Internal Prospective Validation of the Cancer Admission Score (CAS) Prediction Model
The goal of this single center prospective observational study is to determine the agreement between the cancer admission score (CAS) predicted disposition and the actual disposition in patients with an active cancer diagnosis…
- Trial name
- ONCOMING (NCT06558487)
- Testing
- Cancer Admission Score Prediction Model
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
Suicidal Ideation, Suicidal Ideas
Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation
Approximately 20% of Canadian adolescents experience thoughts of suicide, or suicidal ideation (SI), and suicide is the second leading cause of death among Canadians aged 15-19 years.
- Trial name
- KSI (NCT06366334)
- Testing
- Ketamine Hydrochloride, Normal saline
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Eastern Ontario
Acute Cardiogenic Pulmonary Edema, Hypercapnic Respiratory Failure
High Flow Nasal Cannula Therapy for Early Management of Acute Hypercapnic Cardiogenic Pulmonary Edema in the Emergency Department
High flow nasal therapy (HFNT) has not been well evaluated for treating hypercapnia The purpose of this study is to determine whether high flow nasal therapy (HFNT) can decrease hypercapnia and improve respiratory distress…
- Trial name
- preopticap (NCT03883555)
- Testing
- High flow nasal therapy (HFNT) : Optiflow™, Non invasive ventilation (niv)
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Montpellier
Ischemic Stroke
HEMS for Mechanical Thrombectomy
Elapsed time from the onset of stroke symptoms to the point of revascularization is the key determinant of the optimal outcome of acute ischemic stroke.
- Trial name
- NCT04834284
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Tampere University Hospital
Pain Management, Nonpharmalogical Pain Management
Impact of Buzzy and Finger Puppets on Children's Pain, Fear, and Anxiety During Venipuncture
This study evaluates the impact of the Buzzy device and finger puppet distraction on pain, fear, and anxiety in children aged 4-7 undergoing venipuncture in a pediatric emergency department.
- Conditions
- Pain Management, Nonpharmalogical Pain Management, Children Pain Management
- Trial name
- Pain Relief (NCT06849648)
- Testing
- The Buzzy Device, Finger Puppet
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Kutahya Health Sciences University
Rhabdomyolysis, Virtual Reality
Evaluation of the Effectiveness of Using Virtual Reality Glasses in Prehospital Intervention Training for Crush Syndrome
This research is a randomized controlled study designed to develop and evaluate the effectiveness of a video-based virtual reality (VR) simulation for prehospital intervention training of crush syndrome for paramedic students.
- Conditions
- Rhabdomyolysis, Virtual Reality, Emergency Medical Services, Disaster Medicine
- Trial name
- NCT07361835
- Testing
- Virtual reality-based crush syndrome training, Traditional theoretical lecture
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Ege University
Difficult Intravenous Access in Pediatrics
Ultrasound Guided IV Access in a Pediatric Emergency Department
The primary objective is to determine whether the use of ultrasound guidance compared to standard IV access improves the proportion of successful IV placement on a first attempt for children in a pediatric emergency department…
- Trial name
- USgIV (NCT02125552)
- Testing
- Ultrasound guidance, Traditional intravenous access
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Children's Hospital of Philadelphia
COPD Exacerbation
Magnesium Sulfate Versus Ipratropuim Bromide in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Treatment with short acting β2 agonists for exacerbations of COPD results in clinical improvement. It has not been established whether combining short acting β2 agonists to other bronchodilators is more effective than β2 agonists…
- Trial name
- NCT01136421
- Testing
- Ipratropium bromide, Magnesium Sulfate
- Where
- 2 sites in Tunisia
- Volunteers
- 124 people
- Sponsor
- University of Monastir
Sickle Cell Disease (SCD), Vaso-Occlusive Crises
Pleuropulmonary Ultrasound Imaging in Patients With Sickle Cell Disease in a Vaso-occlusive Crisis. "ECHODREP"
Introduction Sickle cell disease is the most common inherited genetic disorder in France and worldwide. Its main acute manifestation is vaso-occlusive crisis, a frequent reason for emergency department visits.
- Conditions
- Sickle Cell Disease (SCD), Vaso-Occlusive Crises, Acute Chest Syndrome
- Trial name
- ECHODREP (NCT07782489)
- Testing
- Pleuropulmonary ultrasound
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fig. Impetuous
Based on the Data from the Zhejiang Emergency Center, Explore the Independent and Interactive Effects of the Association Between Meteorological Factors and Air Pollution and the Number of Emergency Personnel, Identify the Relevant Vulnerable Population Characteristics, Sensitive Disease Types
Based on the health data from Zhejiang Emergency Command Center, combined with meteorological, air pollution, land use and socio-economic data of Zhejiang Province, distributional lag nonlinear models, grouped weighted quantile…
- Trial name
- NCT06798987
- Testing
- Meteorological conditions and air pollution
- Where
- China
- Volunteers
- 1,500,000 people
- Sponsor
- Li hengjie
Acute Respiratory Failure
Pragmatic Trial Examining Oxygenation Prior to Intubation
Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States.
- Trial name
- PREOXI (NCT05267652)
- Testing
- Preoxygenation with Non-Invasive Positive Pressure Ventilation, Facemask Oxygen
- Where
- 16 sites in United States
- Volunteers
- 1,301 people
- Sponsor
- Vanderbilt University Medical Center
Syncope
CSRS Implementation - A Pilot Study
Syncope is a common reason for emergency department (ED) presentation. While often benign, some patients have serious and life-threatening underlying causes, both cardiac and non-cardiac, which may or may not be apparent at the…
- Trial name
- NCT04790058
- Testing
- Knowledge translation of the CSRS practice recommendations
- Where
- Canada
- Volunteers
- 900 people
- Sponsor
- Ottawa Hospital Research Institute
Car Seats, Injuries
Evaluating Models for Dissemination of Injury Prevention Information in the Pediatric Emergency Department Setting
This study examines the Pediatric Emergency Department as a location for increasing safe car seat practices by parents who are not restraining their children appropriately in motor vehicles.
- Trial name
- NCT00476255
- Testing
- Enhanced Standard Care (ESC), Brief Motivational Intervention (BMI)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Asthma, Smoking Cessation
Pediatric Emergency Department Decision Support System to Reduce Secondhand Smoke
This two phase study will develop and evaluate a Pediatric Emergency Department (PED) Decision Support System (DSS)-Electronic Medical Records (EMR) System to facilitate the identification of smokers and the delivery of a Second…
- Trial name
- NCT02489708
- Testing
- Cessation Counseling
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
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