Clinical trials: Emergency Departments
COPD, COPD Exacerbation Acute
The Reducing REVISITS Study: A Cluster RCT
This type II hybrid effectiveness-implementation trial will concurrently study the comparative effectiveness of virtual vs. in-person COPD care transition programs implemented via virtual mentored implementation approaches with…
- Trial name
- REVISITS (NCT05568043)
- Testing
- COPD Transitions of Care Intervention Bundle: Virtual Interventions, COPD Transitions of Care Intervention Bundle: In-Person Interventions
- Where
- United States
- Volunteers
- 384 people
- Sponsor
- University of Chicago
COVID 19 Vaccine
Combination Assessment Trial of COVID-19 Vaccines (COMBAT-COVID)
This is a randomized, phase II trial which will be conducted among volunteers aged 18 years and above in Karachi, Lahore and Islamabad, Pakistan. The trial will have nine arms and is an open label study.
- Trial name
- COMBAT-COVID (NCT05162482)
- Testing
- BIBP (CNBG, Sinopharm) WIV, CanSinoBIO, AstraZeneca ChAdOx
- Where
- 3 sites in Pakistan
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Preconception Care
Computer-assisted Preventive Health Education for Women of Reproductive Age in Urgent Care Settings
The purpose of this study is to determine whether "video doctor" programs can effectively deliver preventive health messages to women of reproductive age while they wait to be seen in urgent care settings.
- Trial name
- NCT00177515
- Testing
- "video doctor," computer module
- Where
- United States
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pulmonary Embolism
Pulmonary Embolism Diagnosis: Ultrasound Wells Score vs Traditional Wells Score
Pulmonary embolism (PE) should be suspected in patients with dyspnea, chest pain, syncope, shock/hypotension, or cardiac arrest.
- Trial name
- NCT02190110
- Where
- 4 sites in Italy
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Upper Gastrointestinal Bleeding
Risk Stratification of Patients Presenting With Upper Gastrointestinal Bleeding to the Emergency Department Using AIMS65 Score and Red Cell Distribution Width
The rationale of this study in UGIB patients is to assess whether the prediction of mortality and morbidity using AIMS65 score improves when used in combination with RDW in the emergency department setting.
- Trial name
- RUGBE (NCT04825977)
- Testing
- RISK STRATIFICATION USING AIMS65 SCORE AND RDW
- Where
- India
- Volunteers
- 348 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Contraception
Targeted Video Messaging About Emergency Contraception
This research study will assess the real-world effectiveness of Facebook advertising as a strategy to reach women of reproductive age who are at risk of unintended pregnancy with a brief educational intervention about emergency…
- Trial name
- NCT03774368
- Testing
- Emergency contraception website, Emergency contraception video
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Electroencephalography, Consciousness
Development of Consciousness Measure and Monitor Device Based on Electroencephalography
This study aims to develop a consciousness measuring and monitoring device using a single-channel electroencephalogram (EEG).
- Trial name
- NCT04952090
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Hospital
Unspecified Child Maltreatment, Suspected, Unspecified Child Maltreatment, Confirmed
Northwell Health Visits: A Family Connects Pilot Implementation at Northwell Health
Northwell Health Visits (NHV) is a three year pilot replication of the evidence-based model, Family Connects, which is a brief universal Nurse Practitioner home visiting program for new mothers and their infants.
- Conditions
- Unspecified Child Maltreatment, Suspected, Unspecified Child Maltreatment, Confirmed, Postpartum Depression
- Trial name
- NCT03887910
- Testing
- Enhanced Intervention, Intervention
- Where
- United States
- Volunteers
- 840 people
- Sponsor
- Northwell Health
Abdominal Aortic Aneurysm, Endovascular Procedures
Standardization of Physician-Modified Stent Grafts for Abdominal Aortic Aneurysms
This study explores the use of physician-modified stent grafts (PMSGs) for treating abdominal aortic aneurysms that are unsuitable for open surgery or standard endovascular grafts.
- Conditions
- Abdominal Aortic Aneurysm, Endovascular Procedures, Stents, Vascular Surgical Procedures
- Trial name
- RESTORE (NCT06585215)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Acute Coronary Syndrome
Rapid Assessment of Potential Ischaemic Heart Disease With CTCA
This study aims to investigate the effect of early CTCA in patients with suspected or confirmed Acute Coronary Syndrome (ACS) presenting to the Emergency Department (ED) or Medical Assessment Unit (MAU), upon interventions, event…
- Trial name
- RAPID-CTCA (NCT02284191)
- Testing
- CT Coronary Angiogram
- Where
- 37 sites in Jersey, United Kingdom
- Volunteers
- 1,749 people
- Sponsor
- University of Edinburgh
Acute Abdomen, Acute Appendicitis
Diagnostic Accuracy of Emergency Physician Performed Bedside Ultrasound in Suspected Acute Appendicitis
The aim of the study is to evaluate the diagnostic yield and accuracy of bedside emergency physician performed ultrasound in the diagnosis of acute appendicitis.
- Trial name
- NCT02467959
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Antalya Training and Research Hospital
Chest Pain
A Study of the Feasibility of Prehospital Remote Ischemic Conditioning
Prospective, single center, single arm pilot study evaluating the feasibility of delivering remote ischemic conditioning (RIC) by emergency medical services (EMS) in the prehospital setting.
- Trial name
- NCT03400579
- Testing
- autoRIC® device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Traumatic Brain Injury, Computed Tomography
Evaluation of Pediatric Procedural Sedation With Rectal Chloral Hydrate or Intranasal Midazolam
Thousands of children receive sedation for diagnostic and therapeutic interventions annually, and this number is expected to increase. Children are at higher risk for sedation-related complications than adults.
- Conditions
- Traumatic Brain Injury, Computed Tomography, Procedural Sedation
- Trial name
- NCT01402596
- Testing
- Midazolam, Chloral Hydrate
- Where
- Brazil
- Sponsor
- University of Sao Paulo
Hypertension
Reach Out: Emergency Department-Initiated Hypertension Behavioral Intervention Connecting Multiple Health Systems
This study evaluates a health theory based mobile health behavioral intervention to reduce blood pressure (BP) among hypertensive patients evaluated in a community Emergency Department (ED) setting.
- Trial name
- ReachOut ED (NCT03422718)
- Testing
- Healthy Behavior Texts, No healthy behavior texts, BP Monitoring Daily Via Text Messaging
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- University of Michigan
Dyspnea
Emergency Classification According to Fingertip Circulation
Dyspnea is one of the most common reasons for admission to the emergency department[1]. Oxygen saturation has great importance in determining the triage status of patients admitted to the hospital with dyspnea and planning the…
- Trial name
- NCT05742113
- Testing
- Masimo Radical-7
- Where
- Turkey (Türkiye)
- Volunteers
- 1,490 people
- Sponsor
- Manisa Celal Bayar University
Chest Pain
Chest Pain Observation Unit Risk Reduction Trial
The purpose of this study is to determine whether a brief counseling intervention initiated in the chest pain observation unit has a significant impact upon the health attitudes (readiness to change) and cardiovascular…
- Trial name
- NCT00536224
- Testing
- Full counseling, Minimal counseling
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- David A Katz
Dyspnea
Diagnostic Value of Portable Ultrasound for Dyspneic Patient Support in the Emergency Department
The main objective of our study is to compare the effects of two care strategies for dyspneic patients on the length of hospital stay: (1) standard care (=contextual analysis + conventional clinical chest radiography) versus (2)…
- Trial name
- VSCAN-DYSP (NCT01818882)
- Testing
- Standard care, Vscan portable ultrasound device (GE Healthcare, Wauwatosa, WI)
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Acute Heart Failure
Effect of Short-term Prednisone Therapy on C-reactive Protein in Patients With Acute Heart Failure
This is a multicenter, parallel-group, randomized, open-label, controlled trial. Patients with a diagnosis of acute heart failure (AHF) in the emergency department (ED) or after emergency presentation to hospital will be screened…
- Trial name
- CORTAHF (NCT05916586)
- Testing
- Prednisone
- Where
- 3 sites in Armenia
- Volunteers
- 101 people
- Sponsor
- Heart Initiative
Nausea, Vomiting
Isopropyl Alcohol Inhalation as Anti-emetic Therapy in the Emergency Department
Nausea and vomiting is a common and distressing presenting complaint in Canadian emergency departments. Commonly used nausea medications have proven to be effective in certain patient populations, for example cancer patients.
- Trial name
- NCT04464915
- Testing
- Isopropyl alcohol swab
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Pain, Acute, Anxiety Acute
Atmospheric Projection in the Emergency Department
The goal of this clinical trial is to learn about the reduction of pain and anxiety during a minor procedure in the emergency department on adult patients through the visualisation of atmospheric projection as a distraction mean.
- Trial name
- AERIAL-MED (NCT05967988)
- Testing
- Immersive atmospheric projection, Minimal atmospheric projection
- Where
- Switzerland
- Volunteers
- 62 people
- Sponsor
- University of Lausanne Hospitals
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