Clinical trials: Emergency General Surgery
Hemorrhage
Reversal of Dabigatran Anticoagulant Effect With Idarucizumab
Evaluate the reversal of the anticoagulant effects of dabigatran by IV administration of 5.0g idarucizumab in patients treated with dabigatran etexilate who have uncontrolled bleeding or require emergency surgery or procedures.
- Trial name
- NCT02104947
- Testing
- idarucizumab
- Where
- 176 sites in United States, Argentina and 31 more
- Volunteers
- 503 people
- Sponsor
- Boehringer Ingelheim
Surgery, Anesthesia
Surgical Capacity in Zimbabwean Public Hospitals
This study aimed to understand how ready Zimbabwe's public hospitals are to perform essential surgeries, which are critical for treating a wide range of health issues from emergencies like car accidents to planned procedures such…
- Trial name
- NCT06358183
- Testing
- No intervention
- Where
- Zimbabwe
- Volunteers
- 80 people
- Sponsor
- Parirenyatwa Hospital
Bowel Surgery, Emergency Abdominal Surgery
COMPARATIVE OUTCOME OF EARLY AND STANDARD ORAL FEEDING AFTER EMERGENCY BOWEL SURGERY
Informed consent will be obtained from patients or their legal representatives in cases where the patient is unconscious. Patient information, including names, ages, gender, smoking history, comorbidities, and the indication for…
- Conditions
- Bowel Surgery, Emergency Abdominal Surgery, ERAS
- Trial name
- NCT07047729
- Testing
- Early oral feeding, Standard oral feeding
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dr Hamail Khanum
Educational Problems
PBP vs Traditional Training: the T-REC Trial
This randomized controlled trial aims to compare the effectiveness of traditional training approach to training with the proficiency-based progression (PBP) approach for teaching the technical skills (TS) and non-technical skills…
- Trial name
- T-REC (NCT06147128)
- Testing
- Emergency scenario in a simulated setting where open conversion is necessary due to vessel injury during robotic surgery on a dry lab model
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Orsi Academy
Incarcerated Hernia, Appendicitis Acute
Prevention of Postoperative Hernias in Emergency Surgery
The aim of this observational study is to understand the risk factors and incidence of postoperative hernias among patients undergoing emergency surgery.
- Conditions
- Incarcerated Hernia, Appendicitis Acute, Cholecystitis, Acute, Ileus
- Trial name
- PROPHECY (NCT06815822)
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Jan Kochanowski University
Emergency Gastrointestinal Surgery, Mortality Within 30 Days
Construction and Validation of a Prediction Model for All - Cause Mortality Within 30 Days After Surgery in Critically Ill Patients Undergoing Emergency Gastrointestinal Surgery
Gastrointestinal surgeries are crucial for treating digestive tract diseases. However, they often lead to high postoperative infection rates due to long durations, bacterial translocation, weakened immunity, and reduced…
- Trial name
- EGS-30MP (NCT06787157)
- Testing
- Prediction Model Construction
- Volunteers
- 900 people
- Sponsor
- Quan Wang
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Emergency Surgical Procedures, Postoperative Pain
Postoperative Progressive Relaxation Exercises for Pain and Anxiety After Emergency Surgery
This randomized controlled trial investigated the effectiveness of postoperative progressive relaxation exercises (PRE) on pain, anxiety, and physiological parameters among adult patients undergoing emergency general surgery.
- Conditions
- Emergency Surgical Procedures, Postoperative Pain, Postoperative Anxiety
- Trial name
- PRE-ES (NCT07301073)
- Testing
- Progressive Relaxation Exercises (PRE)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Agri Ibrahim Cecen University
Surgery
Natriuretic Peptides - Predictors of In-hospital and Long-term Major Adverse Cardiac Events After Emergency Surgery?
The investigators hypothesize that the level of perioperative natriuretic peptides is associated with in-hospital and long term major adverse cardiac events.
- Trial name
- NCT00942786
- Where
- Austria
- Volunteers
- 297 people
- Sponsor
- Medical University of Graz
Surgical Site Infection
Novosyn® CHD vs Polyglactin 910 Suture to Close Wounds After Emergency or Elective Laparotomy or Laparoscopic Surgery
The aim of the study is to elucidate, if the colonization of bacteria is lower on the Novosyn® CHD suture compared to uncoated Polyglactin 910 suture, which will be assessed by the incidence of surgical site infections (SSI: A1…
- Trial name
- POLYNOVO-CHD (NCT05966961)
- Testing
- Novosyn® in emergency or elective laparotomy or laparoscopic surgery, Polyglactin 910 in emergency or elective laparotomy or laparoscopic surgery
- Where
- 4 sites in Italy, Spain
- Volunteers
- 2,998 people
- Sponsor
- Aesculap AG
Perforated Diverticulitis
A National Study of Clinical Results After Emergency Operation for Perforated Diverticulitis
The aim of this study is to evaluate clinical results and effect on health and well-being in patients operated for perforated diverticulitis with purulent peritonitis by laparoscopic lavage in Sweden when used outside of…
- Trial name
- LapLav (NCT03332550)
- Testing
- Laparoscopic lavage, Colon resection
- Where
- Sweden
- Volunteers
- 669 people
- Sponsor
- Sahlgrenska University Hospital
Emergency Surgery, Surgical Site Infections
Irrisept in Emergency General Surgery Patients
This is a single institution, randomized study conducted to determine if irrigation with Irrisept in emergency general surgery patients results in lower surgical site infections compared to normal saline irrigation.
- Trial name
- NCT07048899
- Testing
- Chlorhexidine, Normal Saline
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Anesthesia
Anesthesia for Emergency Orthopedic Surgery
The aim of this retrospective study is to evaluate the preferred anaesthesia techniques in our clinic for emergency orthopedic surgery at a 1 year period.
- Trial name
- NCT02820922
- Testing
- Orthopedic
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Sakarya University
Emergency Laparotomy, Inflammatory Response
Troponin T and Emergency High-risk Abdominal Surgery
To assess whether perioperatively elevated TnT levels, using high sensitivity troponin T (hsTnT) measurements, are associated with an increased risk of postoperative mortality as well as severe postoperative complications.
- Conditions
- Emergency Laparotomy, Inflammatory Response, Myocardial Injury
- Trial name
- NCT04878159
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Educational Problems, Orthopedic Disorder
Assessment of an Orthopedic Surgery Rotation on Musculoskeletal Competency in Emergency Medicine Residency Training
Patient commonly present with orthopedic injuries in the emergency department. Musculoskeletal education has not historically been emphasized in American medical schools, and the effectiveness of an orthopedic surgery rotation…
- Conditions
- Educational Problems, Orthopedic Disorder, Emergencies
- Trial name
- NCT03944746
- Testing
- Education Curriculum
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Jared L. Cohen
Emergency Surgery
Risk Stratification for Abdominal Emergency Surgery: a Cohort Study
The goal of this retrospective observational study is to identify risk factors of unwanted outcomes (in-hospital morbidity and mortality) among patients undergoing emergency abdominal surgery.
- Trial name
- NCT06501170
- Testing
- Retrospective Data Analysis of Emergency Abdominal Surgery Outcomes
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking Union Medical College Hospital
Bowel Obstruction
Emergency General Surgery for Non-trauma
This study will observe the postoperative morbidity and mortality trends in patients with non- traumatic abdominal pathology who will undergo emergency general surgery.
- Trial name
- NCT04539028
- Testing
- Emergency Abdominal surgery
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- New York Medical College
Rapid Sequence Induction
Classic and Modified Rapid Sequence Induction for Prevention of Gastric Content Regurgitation
Induction of anesthesia induces a loss of protective upper airway reflexes and is associated with gastric content regurgitation.
- Trial name
- NCT04312425
- Testing
- Modified rapid sequence induction, Classic rapid sequence induction
- Where
- China
- Volunteers
- 8,601 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Emergencies
Validation of Emergency Surgery Score (ESS) in Egyptian Patients Undergoing Emergency Laparotomy
To assess the accuracy of Emergency Surgery Score in predicting postoperative morbidity and mortality in emergency laparotomy.
- Trial name
- NCT05639920
- Testing
- Scoreing
- Volunteers
- 138 people
- Sponsor
- Assiut University
Mechanical Ventilation Complication
Rehabilitation Program for Weaning From Mechanical Ventilator
Statement of the problem: Are there any differences between comprehensive rehabilitation program consisted of (peripheral muscle training and functional training) combined with inspiratory muscle training and traditional chest…
- Trial name
- NCT04021615
- Testing
- Comprehensive physical therapy rehabilitation program combined with inspiratory muscle training, Traditional chest physical therapy rehabilitation program combined with inspiratory muscle training
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sherin Hassan Mohammed Mehani