Clinical trials: Emergency High-risk Abdominal Surgery
Emergency High-risk Abdominal Surgery
Functional Performance Following Emergency High-risk Abdominal Surgery
Emergency abdominal surgery is associated with high mortality rates, multiple postoperative complications and prolonged duration of hospital admission.
- Trial name
- NCT02124356
- Testing
- Evaluation of functional performance
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Hvidovre University Hospital
Emergency Abdominal Surgery
Intermediate Care - Effect on Mortality Following Emergency Abdominal Surgery
The objective of this trial is to evaluate postoperative intermediate care versus ward care in patients who have undergone emergency abdominal surgery with a perioperative Acute Physiology and Chronic Health Evaluation (APACHE)…
- Trial name
- InCare (NCT01209663)
- Testing
- Postoperative Intermediate Care
- Where
- 7 sites in Denmark
- Volunteers
- 286 people
- Sponsor
- Copenhagen University Hospital at Herlev
Postoperative Morbidity, Postoperative Mortality
Hemostasis Evolution During Fluid Loading in Abdominal Surgery. Effects of Fluid Choice: Saline Versus Hydroxyethyl Starch (HAEMO Study)
The primary purpose of the study is to evaluate whether the type of fluid (0.9% saline or 6% Hydroxyethyl starch 130/0.4) in the context of an individualized goal-directed fluid therapy is associated with a difference in…
- Conditions
- Postoperative Morbidity, Postoperative Mortality, Hemostasis Change
- Trial name
- HAEMO (NCT03420261)
- Testing
- 0.9% saline, HES 130/0.4
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Clermont-Ferrand
Abdomen, Acute, Myocardial Injury After Non-cardiac Surgery
The Effects of Troponin I Surveillance Among Patients Undergoing Acute High-risk Abdominal Surgery
Treatment of disorders such as gastrointestinal tract (GI) perforation, ischemia and obstruction often require acute high-risk abdominal surgery, which is associated with a high risk of complications such as myocardial injury…
- Conditions
- Abdomen, Acute, Myocardial Injury After Non-cardiac Surgery, Troponin I, Myocardial Injury
- Trial name
- NCT05992961
- Testing
- Troponin I
- Where
- Denmark
- Volunteers
- 558 people
- Sponsor
- Nordsjaellands Hospital
Postoperative Morbidity, Postoperative Mortality
Fluid Loading in Abdominal Surgery: Saline Versus Hydroxyethyl Starch (FLASH Study)
The primary purpose of the study is to evaluate whether the type of fluid (0.9% saline or 6% Hydroxyethyl starch 130/0.4) in the context of an individualized goal-directed fluid therapy is associated with a difference in…
- Trial name
- FLASH (NCT02502773)
- Testing
- Hydroxethyl starch
- Where
- France
- Volunteers
- 826 people
- Sponsor
- University Hospital, Clermont-Ferrand
Acute High-risk Abdominal Surgery (AHA)
Early Mobilization Following Emergency Abdominal Surgery
Acute High-risk abdominal surgery (AHA) is associated with high mortality rates, multiple postoperative complications and prolonged duration of hospital admission.
- Trial name
- NCT03662932
- Testing
- Early intensive mobilization
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Morten Tange Kristensen PT, PhD
Perforated Viscus, Intestinal Obstruction
Acute High-risk Abdominal Surgery Study - an Optimized Perioperative Course
The objective of this study is to implement an optimized perioperative course for patients undergoing acute high-risk abdominal surgery in order to improve the outcome.
- Trial name
- AHA (NCT01899885)
- Testing
- AHA (Acute Highrisk Abdominalsurgery): Optimized Course
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Hvidovre University Hospital
Abdomen, Acute
The Hospital Volume Relationship in Emergency Laparotomy Outcomes
Introduction 'Emergency Laparotomy' is an umbrella term for a set of commonly performed procedures which are known to carry a significant risk of mortality and morbidity.
- Trial name
- NCT02047812
- Where
- United Kingdom
- Volunteers
- 40,000 people
- Sponsor
- University of Edinburgh
Myocardial Injury After Non-cardiac Surgery, Abdomen, Acute
Troponin I Level and Mortality in Acute Abdominal Surgery
The goal of this prospective cohort study is to estimate the incidence of myocardial injury after non-cardiac surgery (MINS) in patients undergoing acute high-risk abdominal surgery.
- Trial name
- NCT05933837
- Testing
- Troponin I
- Where
- Denmark
- Volunteers
- 341 people
- Sponsor
- Nordsjaellands Hospital
Emergency Laparotomy, Inflammatory Response
Troponin T and Emergency High-risk Abdominal Surgery
To assess whether perioperatively elevated TnT levels, using high sensitivity troponin T (hsTnT) measurements, are associated with an increased risk of postoperative mortality as well as severe postoperative complications.
- Conditions
- Emergency Laparotomy, Inflammatory Response, Myocardial Injury
- Trial name
- NCT04878159
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Laparotomy, Peritonitis
Standardized Perioperative Management of Patients Operated With Acute Abdominal Surgery in a High-risk Emergency Setting
The objective of the study is to handle patients with the need for an acute laparotomy according to a standardised perioperative protocol and to document the measurement as they are performed (i.e.
- Conditions
- Laparotomy, Peritonitis, Ileus, Perforated Bowel
- Trial name
- SMASH (NCT03549624)
- Testing
- Standardised protocol for the perioperative management in patients in need of an acute laparotomy
- Where
- Sweden
- Volunteers
- 1,435 people
- Sponsor
- Sahlgrenska University Hospital
Diabetes (Insulin-requiring, Type 1 or Type 2)
Investigation of the Effectiveness of Prophylactic NPWT (ciNPWT) in High-risk Diabetic Patients With Acute Laparotomy Wounds
The aim of this study is to evaluate the effectiveness of prophylactic Negative Pressure Wound Therapy (NPWT) in patients with diabetes mellitus undergoing laparotomy who are at high risk for Surgical Site Infections (SSI).
- Trial name
- NCT07392853
- Testing
- Prophylactic/Incisional Negative Pressure Wound Therapy
- Where
- Hungary
- Volunteers
- 110 people
- Sponsor
- Semmelweis University