Clinical trials: Emesis
Emesis
The Antiemetic Effects of Increased Splanchnic Perfusion, Induced by the Gut Hormone GIP, in Healthy Individuals
This study investigates whether the gut hormone glucose-dependent insulinotropic polypeptide (GIP) can reduce feelings of nausea.
- Trial name
- GIP EMESIS (NCT07687589)
- Testing
- Glucose-dependent Insulinotropic Polypeptide (GIP), GLP-1 (7-36) amide, Apomorphine Injectable Solution
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Pregnancy Emesis, Nausea
Alternate Nostril Breathing (ANB) for 1st Trimester Nausea and Vomiting
This is a prospective, two-arm, non-blinded randomized controlled study designed to evaluate the effects of a one-week alternate nostril breathing (ANB) intervention on nausea and vomiting severity in pregnant individuals during…
- Trial name
- NCT07378839
- Testing
- Alternate Nostril Breathing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Minnesota
Emesis Pregnancy
Effect of Transcutaneous Electrical Nerve Stimulation Versus Capsicum Plaster on Emesis Gravidarum
This study will be conducted to determine the difference between the effect of transcutaneous electrical nerve stimulation and capsicum plaster on emesis gravidarum.
- Trial name
- NCT06520735
- Testing
- Transcutaneous electrical nerve stimulation, Capsicum plaster
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Emesis Pregnancy
Effect of Kinesiotape on Emesis in Pregnant Women
This study will be conducted to investigate the effect of kinesiotaping on emesis in pregnant women.
- Trial name
- NCT06625632
- Testing
- Antiemetic Drug, Vitamin B6, Home care advice
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Emesis, Postoperative, Maxillofacial Abnormalities
Effects of Antiemetic Agents in Orthognathic Surgery Patients
In an effort to prevent or treat consistently high rates of PONV following maxillofacial operations, several medications, techniques and multimodal protocols have been studied.
- Trial name
- NCT06454825
- Testing
- Intravenous drug
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Pregnancy Early, Emesis
Promoting Safe Medication Use in Pregnancy in the Era of Real-World Data - The SafeStart Study
The background for this project is the growing concern about women's use of medications during pregnancy. Several studies have shown that up to 80% of all pregnant women use at least one medication during pregnancy, most commonly…
- Conditions
- Pregnancy Early, Emesis, Medication Adherence
- Trial name
- SafeStart (NCT04182750)
- Testing
- Pharmacist consultation
- Where
- Norway
- Volunteers
- 369 people
- Sponsor
- Hedvig Marie Egeland Nordeng
Hyperemesis Gravidarum, Emesis
MinSafeStart - Decision Aid Tool for Better Treatment of Nausea and Vomiting During Pregnancy
Nausea and vomiting in pregnancy (NVP) is affecting up to 70% of pregnant women. Studies have also shown that NVP may have a profound impact on pregnant women's wellbeing and that even mild NVP symptoms have been shown to…
- Conditions
- Hyperemesis Gravidarum, Emesis, Emesis Pregnancy
- Trial name
- NCT04719286
- Testing
- MinSafeStart app
- Where
- Norway
- Volunteers
- 217 people
- Sponsor
- Hedvig Marie Egeland Nordeng
Lean Body Mass, Cannabis
The Effect of Cannabidiol on Lean Body Mass in Patients Receiving Chemotherapy
An intervention study on the effect of cannabidiol on lean body mass in cancer patients receiving chemotherapy, at the department of Clinical Oncology at Zealand University Hospital, Roskilde, Denmark.
- Conditions
- Lean Body Mass, Cannabis, Cancer, Nausea
- Trial name
- NCT04585841
- Testing
- Cannabidiol
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Copenhagen
Healthy Diet, Thyroid Hypertrophy
The Effect of Healthy Eating Index on Maternal Thyroid Volume in Hyperemesis Gravidarum
The relationship between healthy eating index and maternal thyroid volume in patients with hyperemesis gravidarum is planned.
- Conditions
- Healthy Diet, Thyroid Hypertrophy, Pregnancy Emesis
- Trial name
- NCT04528186
- Testing
- Maternal thyroid volume
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Batman Training and Research Hospital
Emesis
Evaluation of Meclizine Orodispersible Tablet Pharmacokinetic in Human Volunteers
The main goal of this study is to develop a new oro-dissolvable/dispersible tablet that will augment the dual rapid absorption of MCZ from the buccal cavity as well as prolonging that from the GIT.
- Trial name
- NCT04564144
- Testing
- Meclizine Hydrochloride
- Where
- Egypt
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Nausea, Emesis
Post- Surgery Recovery: Nerve Blocks w/ Sedation vs. Nerve Block w/ Either Sedation/Gen. Anesthesia
Nausea after surgery may negatively influence patient satisfaction, may delay discharge, and cause unexpected hospital admissions.
- Trial name
- NCT02602080
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Hospital for Special Surgery, New York
Pregnancy Emesis
Aromatherapy as Treatment for n/v of Pregnancy
A double-blinded randomized controlled trial comparing essential oil aromatherapy versus placebo for treatment of first trimester nausea and vomiting of pregnancy.
- Trial name
- NCT03609567
- Testing
- Aromatherapy
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Advanced Cancer, Nausea
DAnish Nausea Study In Advanced Cancer-Epidemiology: A Danish Multicenter Trial to Investigate the Prevalence and Treatment of Nausea and/or Vomiting in Patients With Advanced Cancer.
The study aims to investigate the prevalence and treatment of nausea and/or vomiting in patients with advanced cancer not receiving chemotherapy or irradiation.
- Conditions
- Advanced Cancer, Nausea, Emesis
- Trial name
- NCT02980289
- Where
- Denmark
- Volunteers
- 821 people
- Sponsor
- Signe Harder
Emesis, Vomiting
Trial to Evaluate Efficacy of Olanzapine With Short-acting 5HT3 Inhibitors in Chemotherapy-induced Nausea & Vomiting (CINV) Prophylaxis
Olanzapine-containing regimens for CINV prophylaxis may provide even better protection than aprepitant-containing regimens.
- Conditions
- Emesis, Vomiting, Nausea Post Chemotherapy, Nausea
- Trial name
- OlaCINV (NCT03478605)
- Testing
- Olanzapine, Aprepitant Pill, Ondansetron
- Where
- Russia
- Volunteers
- 130 people
- Sponsor
- Blokhin's Russian Cancer Research Center
Emesis
Prevention of Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients.
For breast cancer patients receiving chemotherapy regimens, the use of a validated emesis (nausea and vomiting) risk calculator will provide superior anti-emetic (nausea and vomiting) control compared with "standard" anti-emetic…
- Trial name
- ER11-02 (NCT01913990)
- Testing
- Dexamethasone, Ondansetron, Aprepitant, Arm A: Standard Anti-emetic regimen
- Where
- Canada
- Volunteers
- 323 people
- Sponsor
- Ottawa Hospital Research Institute
Postoperative Vomiting, Postoperative Nausea
Prophylaxis of Postoperative Nausea and Vomiting After Cardiac Surgery
To investigate the role of postoperative nausea and vomiting risk factors assessment after cardiac surgery. We designed a randomized controlled study comparing standard care (no risk factor assessment and no intervention) with…
- Conditions
- Postoperative Vomiting, Postoperative Nausea, Postoperative Emesis
- Trial name
- PONVACS (NCT02744495)
- Testing
- Betamethasone, Droperidol
- Where
- France
- Volunteers
- 502 people
- Sponsor
- Hôpital Privé de Parly II - Le Chesnay
Emesis
Comparison of Olanzapine and Metoclopramide For Treatment Of bReakThrough Emesis
This trial is designed to evaluate olanzapine compared to the metoclopramide in the treatment of break through emesis after prophylaxis with dexamethasone, 5-HT 3 receptor antagonists and aprepitant in patients receiving…
- Trial name
- COMFORT (NCT01148264)
- Testing
- olanzapine, metoclopramide
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Karin Jordan
Non-small Cell Lung Cancer, Vomiting
Study Assessing Fosaprepitant in Advanced NSCLC Patients Treated With Carboplatin Based Chemotherapy
This study evaluates the addition of fosaprepitant to currently available antiemtic treatments of carboplatin chemotherapy-induced nausea and vomiting in advanced non-small cell lung cancer patients.
- Conditions
- Non-small Cell Lung Cancer, Vomiting, Nausea, Emesis
- Trial name
- NCT02407600
- Testing
- FOSAPREPITANT (Emend)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Ajeet Gajra
Emesis
Pharmacokinetic Evaluation of Subcutaneous Versus Intravenous Palonosetron in Cancer Treated With Chemotherapy
This trial compares the pharmacokinetics of palonosetron administered subcutaneously and intravenously.
- Trial name
- NCT01046240
- Testing
- Palonosetron
- Where
- Spain
- Volunteers
- 29 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Emesis
Aprepitant in the Prevention of Cisplatin-induced Delayed Emesis
The aim of the study is to compare efficacy and tolerability of aprepitant plus dexamethasone versus metoclopramide plus dexamethasone in the prevention of cisplatin-induced delayed emesis in patients that received aprepitant…
- Trial name
- NCT00869310
- Testing
- aprepitant + dexamethasone, metoclopramide + dexamethasone
- Where
- Italy
- Volunteers
- 303 people
- Sponsor
- S. Maria Hospital, Terni