Clinical trials: Encopresis
Rectal Cancer
Italian Validation of the LARS Score
BACKGROUND and RATIONALE Colorectal cancer, with 49,000 new diagnoses expected in 2019 (27,000 in men and 22,000 in women) represents, in Italy, the third neoplasm in men (14%) and the second in women (12%).
- Trial name
- NCT04406311
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Faecal Incontinence
Long-term Efficacy of Percutaneous Tibial Nerve Stimulation Applied to Patients With Faecal Incontinence.
Percutaneous tibial nerve stimulation (PTNS) is an ambulatory therapy validated for patients with Faecal Incontinence (FI) refractory to conservative treatment with proved short and mid-term efficacy.
- Trial name
- PTNSLONG (NCT05016453)
- Where
- Spain
- Volunteers
- 139 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Pelvic Floor Dysfunction, Perineal Laceration
Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled Trial
The goal of this clinical trial is to determine whether using a soft perineal protection device (BabySlide®) in addition to standard manual perineal support during vaginal delivery can reduce the risk of perineal trauma in…
- Conditions
- Pelvic Floor Dysfunction, Perineal Laceration, Wound Dehiscence, Anal Incontinence
- Trial name
- PeriPROTECT (NCT07862660)
- Testing
- Perineal protection device, BabySlide, Standard manual perineal support
- Where
- Sweden
- Volunteers
- 4,226 people
- Sponsor
- Region Skane
Anal Incontinence or Constipation
Does Body Position Influence Pressure Recording by High-resolution Manometry ?
The anorectal manometry is the gold standard in the evaluation of anorectal function. Several techniques are currently used (balloons, perfused catheters) and are always performed in the supine position.
- Trial name
- NCT01946334
- Testing
- anorectal manometry and high-resolution three-dimensional
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Faecal Incontinence, Bowel Incontinence
UK Trial of Percutaneous Tibial Nerve Stimulation in Patients With Faecal Incontinence
Faecal incontinence occurs when a person passes faeces (stools) without the usual control. It is a distressing condition that is actually very common although under-reported because of embarrassment.
- Trial name
- CONFIDeNT (NCT02349334)
- Testing
- Percutaneous Tibial Nerve Stimulation
- Volunteers
- 227 people
- Sponsor
- Queen Mary University of London
Frailty Syndrome, Fall in Nursing Home
Digital Intelligent Assistant for Nursing Application
This is an observational study that intends to compare falls or fall-risk related alarms derived from a three-dimensional sensor system with the clinical reality definded by attending nurses.
- Conditions
- Frailty Syndrome, Fall in Nursing Home, Dementia, Delirium in Old Age
- Trial name
- DIANA (NCT04393272)
- Testing
- Three dimensional sensor system designed for fall detection (Fearless)
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Geriatrische Klinik St. Gallen
Anal Incontinence
Polyacrylamide Hydrogel Injection Treatment for Anal Incontinence
A randomized study to evaluate the safety and effects of transanal submucosal polyacrylamide hydrogel injection therapy for anal incontinence.
- Trial name
- NCT02550899
- Testing
- Transanal submucosal injection group 1, Transanal submucosal injection group 2, Transanal submucosal injection group 3
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Faecal Incontinence, Fecal Incontinence
Sacral Nerve Stimulation for Faecal Incontinence - Placebo or Clinical Effective
Sacral nerve stimulation (SNS) has over the last 20 years been recognised as an efficient treatment option for faecal incontinence (FI).
- Trial name
- SNS (NCT03261622)
- Testing
- Sacral nerve stimulation at different stimulation amplitudes
- Where
- Denmark
- Volunteers
- 73 people
- Sponsor
- University of Aarhus
Spinal Cord Injuries, Constipation
Pharmacokinetics of Neostigmine and Glycopyrrolate
A group of 6 able-bodied healthy volunteers will receive Neostigmine (NEO) and Glycopyrrolate (GLY) intravenously and via 2 methods of Iontophoresis (ION): one-patch and two-patch administration, with subsequent blood draws over…
- Conditions
- Spinal Cord Injuries, Constipation, Fecal Incontinence, Neurogenic Bowel
- Trial name
- NCT04027972
- Testing
- Combination of Neostigmine and Glycopyrrolate, I-Box by Dynatronics
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Urinary Incontinence, Anal Incontinence
Pelvic Floor Muscle Training During Pregnancy
The project seeks to investigate effectiveness of PFMT during pregnancy.
- Conditions
- Urinary Incontinence, Anal Incontinence, Pelvic Organ Prolapse, Sexual Dysfunction
- Trial name
- NCT07104292
- Testing
- PFMT, Standard care
- Where
- Denmark
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Fecal Incontinence
Autologous Cell Therapy for Treatment of Fecal Incontinence
The aim of this clinical study is to investigate the safety and feasibility of Autologous Muscle Derived Cells (AMDC, generic name iltamiocel, preparation of a patient's own cells) injection into the anal sphincter for treatment…
- Trial name
- NCT01600755
- Testing
- Iltamiocel
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 53 people
- Sponsor
- Cook MyoSite
Parturition
Perineal Echography in the Delivery Room for the Detection of Anal Lesions
The main objective of this study is to compare the rate of anal incontinence (measured by the Wexner score, qualitative and quantitative (> 4)) at 3 months post partum among primiparas with vaginal tears ≥ 2nd degree who receive…
- Trial name
- OASIS 1 (NCT01320995)
- Testing
- Perineal ultrasound
- Where
- 2 sites in France
- Volunteers
- 111 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Spinal Cord Injuries, Constipation
Neostigmine and Glycopyrrolate by Iontophoresis
To determine a lower effective dose of neostigmine to induce bowel evacuation by transcutaneous administration by iontophoresis.
- Conditions
- Spinal Cord Injuries, Constipation, Fecal Incontinence, Neurogenic Bowel
- Trial name
- NCT06351995
- Testing
- Combination of Neostigmine and Glycopyrrolate, I-Box by Dynatronics
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Faecal Incontinence, Prostate Cancer
Faecal Incontinence in Prostate Cancer Survivors Treated Whith Radiotherapy
The objective of the study is to determine the incidence of faecal incontinence in prostate cancer survivors treated with moderately hypofractionated radiation therapy and correlate the dose received by the anal sphincter with…
- Trial name
- NCT04262609
- Testing
- hypofractionated radiotherapy
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Consorci Sanitari de Terrassa
Fecal Incontinence
EPIC :Anal Incontinence After Delivery. Secondary Prevention With Caesarean Section.
Anal incontinence is frequent and treatment is difficult. One of the most important reasons is traumatic delivery. 10 % of women develop anal incontinence after first delivery.
- Trial name
- EPIC (NCT00632567)
- Testing
- caesarean section, vaginal delivery
- Where
- France
- Volunteers
- 554 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Faecal Incontinence
Efficacy of Acupuncture as a Treatment for Faecal Incontinence
Overall Aim: To improve the long-term management outcomes for faecal incontinence (FI); through the implementation of new alternative treatment to complement existing treatment options, and enable better utilization of limited…
- Trial name
- NCT04276350
- Testing
- Acupuncture, Best Medical Therapy
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- Singapore General Hospital
Perineum; Injury, Anal Incontinence
Efficacy of Antenatal Perineal Massage in Reducing Postpartum Morbidities
A randomized controlled trial was undertaken at Rajavithi Hospital, Bangkok, Thailand, encompassing 106 primigravidae within the period of December 2023 to June 2024.
- Conditions
- Perineum; Injury, Anal Incontinence, Urinary Incontinence
- Trial name
- NCT06162312
- Testing
- Antenatal perineal massage
- Where
- Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Pelvic Floor Disorders, Obstetric Trauma
Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth
This is a single-center prospective cohort study sponsored by the University Hospitals Leuven (UZ). Women will undergo a pelvic floor ultrasound and will be asked to fill out a questionnaire at the time of their admission into…
- Conditions
- Pelvic Floor Disorders, Obstetric Trauma, Urinary Incontinence, Anal Incontinence
- Trial name
- DeliverUU (NCT05530681)
- Testing
- Questionnaire, Pelvic floor ultrasound
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Body Image, Urinary Incontinence
Pelvic Floor Dysfunction and Its Influence on Body Image and Sexual Function
The first objective to determinate the prevalence of pelvic floor dysfunction in pregnant women and in the first year postpartum.
- Conditions
- Body Image, Urinary Incontinence, Anal Incontinence, Anorectal Disorder
- Trial name
- PFD-BI (NCT03591393)
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Faecal Incontinence, Faecal Incontinence With Faecal Urgency
Acs-Tens Treatment for Faecal Incontinence: a RCT With Sham-controls
This study assess the effectiveness on AcuTENS on the treatment of faecal incontinence
- Conditions
- Faecal Incontinence, Faecal Incontinence With Faecal Urgency, Neuromodulation, Transcutaneous Electric Nerve Stimulation
- Trial name
- NCT04749316
- Testing
- AcuTENS
- Where
- Hong Kong
- Volunteers
- 53 people
- Sponsor
- Chinese University of Hong Kong