Clinical trials: End Stage Chronic Renal Failure
Multiple Organ Failure, End Stage Cardiac Failure
Timing of Acute Palliative Care Consultation in Critically Ill Patients
A prospective randomized controlled trial studying the ordering of palliative care consultations in the emergency department (Ig) versus later palliative care consultations in the hospital--ICU or hospital ward(Cg).
- Conditions
- Multiple Organ Failure, End Stage Cardiac Failure, End Stage Chronic Obstructive Airways Disease, Chronic Kidney Disease Stage 5
- Trial name
- NCT02858778
- Testing
- Early order of palliative care consultation
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Wayne State University
Anemia, Heart Failure
An Evaluation of the Causes of Anemia in Patients With Heart Failure
Anemia is frequent in patients with heart failure. Few studies have clearly addressed the causes of anemia in patients with HF. The purpose of this study is to evaluate differences in blood concentrations of various substances…
- Conditions
- Anemia, Heart Failure, Chronic Renal Failure
- Trial name
- ANCHOR (NCT00834691)
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- Montreal Heart Institute
Stroke, End Stage Renal Failure on Dialysis
Evaluating the Feasibility of a Piezoelectric Smart Sensor as an Aid to Help Clinicians Screen for the Development of Pneumonia in an At-risk Population
This proposed research aims to evaluate the feasibility of the piezoelectric sensor as an aid to help clinicians screen for the development of pneumonia in an at-risk population.
- Trial name
- NCT07237633
- Testing
- Piezoelectric sensor
- Where
- Singapore
- Volunteers
- 27 people
- Sponsor
- National University Hospital, Singapore
Acute Renal Failure, Chronic Renal Failure
Effect of Dialysate Temperature on Haemodynamic Stability and Haemodialysis Efficiency
Comparison between dialysate temperatures on haemodynamic stability and haemodialysis efficiency.
- Trial name
- NCT00221598
- Testing
- Haemodialysis with different dialysate temperatures
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Ghent
End Stage Renal Disease, Hemodialysis Complication
Prevalence of Postural Abnormalities in Dialysis Patients
The goal of this observational study is to investigate and compare the prevalence of forward head , hyper kyphosis and balance in hemodialysis and peritoneal dialysis patients.
- Conditions
- End Stage Renal Disease, Hemodialysis Complication, Peritoneal Dialysis Complication
- Trial name
- NCT06350552
- Where
- Iran
- Volunteers
- 395 people
- Sponsor
- Pardis Specialized Wellness Institute
Gut Micrbota and Its Relation to Anemia of CKD Patients
Relationship Between Gut Microbiota And Anemia In Patients With Chronic Renal Failure
The human intestinal tract harbours a diverse and complex microbial community which plays a central role in human health. It has been estimated that our gut contains in the range of 1000 bacterial species and 100-fold more genes…
- Trial name
- NCT03220685
- Testing
- Stool analysis
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sleep Apnea, End Stage Renal Disease
Impact of Different Dialysis on Sleep Apnea in Patients With Renal Failure
The purpose of this study is to determine whether hemodiafiltration, a new form of hemodialysis can improve sleep apnea in patients with end stage kidney disease.
- Trial name
- NCT00380848
- Testing
- Hemodiafiltration
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
End Stage Renal Disease
Vitamin D, Insulin Resistance and Inflammation in ESRD
The broad goal of this study is to understand the mechanisms by which Vitamin D receptor activation leads to changes in insulin signaling in advanced uremia.
- Trial name
- NCT00656032
- Testing
- paricalcitol, cinacalcet
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vanderbilt University
Multimorbidity - End-stage Kidney Disease
Molecular and Clinical Response to a Single Bout of Aerobic Exercise in a Multimorbid Population: a Study From the Consortium on Precision EXercise in Aging
The combination of data from different origins (biological, health, patient-related) has the potential to improve care for the elderly.
- Trial name
- CPExA (NCT05404698)
- Testing
- Aerobic exercise, Control
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- Université de Sherbrooke
Chronic Hepatitis C
Sofosbuvir/Velpatasvir in Adults With Chronic Hepatitis C Virus Infection Who Are on Dialysis for End Stage Renal Disease
The primary objectives of this study are to evaluate safety, efficacy, and tolerability of treatment with sofosbuvir/velpatasvir (SOF/VEL) for 12 weeks in adults on dialysis for end stage renal disease (ESRD) with chronic…
- Trial name
- SOF/VEL ESRD (NCT03036852)
- Testing
- SOF/VEL
- Where
- 22 sites in Australia, Canada and 4 more
- Volunteers
- 59 people
- Sponsor
- Gilead Sciences
Chronic Renal Failure
Effect of Omega 3 Fatty Acids on the Vascular Calcification Biomarkers Fetuin A and Osteoprotegerin in Patients With CRF
study the effect of omega 3fatty acids on the vascular calcification biomarkers Fetuin -A and Osteoprotegerin (OPG) in dialysis patients.
- Trial name
- CRF (NCT03982966)
- Testing
- Omega 3 fatty acids (fish oil) 1000 mg/day oral
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour University
Acute Renal Failure, Chronic Renal Failure
New Non-invasive Methods for Real-time Monitoring of Organ Function.
Measuring novel proteins in the urine of surgical patients that can be used to diagnose impending acute or chronic renal failure.
- Trial name
- RTMKF (NCT00851851)
- Where
- United States
- Volunteers
- 641 people
- Sponsor
- Washington University School of Medicine
Renal Dialysis, Health Literacy Level
Impact of Hospital Pharmacist Intervention on Medication Management in Dialysis Patients
The goal of this clinical trial is to learn if an intervention of a hospital pharmacist could help, dialysis patients managed his treatment. In a first time, the health literacy level will be assed.
- Conditions
- Renal Dialysis, Health Literacy Level, Kidney Disease, Chronic
- Trial name
- IPhaDia (NCT06692231)
- Testing
- Pharmacist intervention
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier de Vichy
Chronic Kidney Disease
Assessment of Dialysis Initiation by a Fuzzy Mathematics Equation
The purpose of this study is to evaluate the impact of the optimal and late initiation of dialysis on the mortality and quality of life in end-stage renal disease (ESRD) patients by the Dialysis Initiation based on Fuzzy…
- Trial name
- ADIFE (NCT03385902)
- Testing
- optimal start time, late start time
- Where
- China
- Volunteers
- 388 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
End Stage Renal Disease (ESRD)
Multi-Site STARgraft (10401) Trial
This is a multi-site, single-blind with parallel group, randomized controlled trial of Healionics STARgraft (10401) vascular graft for hemodialysis access compared with a market-leading commercially available ePTFE vascular graft…
- Trial name
- NCT07557862
- Testing
- STARgraft (10401), Gore Propaten
- Where
- 7 sites in Brazil, Colombia
- Volunteers
- 111 people
- Sponsor
- Healionics Corporation
End Stage Renal Disease
Safety and Immunogenicity of HEPLISAV™ a Hepatitis B Virus Vaccine in Adults on Hemodialysis
The purpose of this study is to compare the immune response to HEPLISAV™ booster injection with the immune response to Engerix-B® and Fendrix® booster vaccinations among patients with end stage renal disease (ESRD) on…
- Trial name
- NCT01195246
- Testing
- HEPLISAV, Engerix-B, Fendrix
- Where
- 19 sites in Germany
- Volunteers
- 155 people
- Sponsor
- Dynavax Technologies Corporation
Anemia of End Stage Renal Disease
Prospective Observational Study of Erythropoietin-Iron Interaction in Anemia of Renal Disease
The purpose of this study is to prospectively collect data on doses of Erythropoietic Stimulating Agents (ESA) and Intravenous Iron, and the markers of erythropoietic activity and iron status.
- Trial name
- NCT01719146
- Testing
- Specimen collection
- Where
- 3 sites in United States
- Volunteers
- 134 people
- Sponsor
- University of Louisville
End Stage Renal Disease
Impact of Envarsus XR® on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile
This will be a single center, prospective, open-label, randomized, controlled trial comparing Envarsus XR® to twice-daily tacrolimus.
- Trial name
- NCT03321656
- Testing
- Tacrolimus, Envarsus XR
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Roberto Gedaly
Renal Failure
Pharmacokinetic Profile and Pharmacodynamic Characteristics of a Furosemide High Dosage Formulation in Patients With Chronic Renal Failure Undergoing Peritoneal Dialysis
Primary Objective: To determine the absolute bioavailability of furosemide 500 mg (Lasix® Special) oral formulation in patients with chronic renal failure undergoing peritoneal dialysis.
- Trial name
- NCT01724788
- Testing
- FUROSEMIDE, FUROSEMIDE (HOE058)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Sanofi
End-stage Renal Disease, Hemodialysis
Protein-bound Toxin Removal Between Limited Blood Flow Super High-flux Online HDF and High-Efficiency Online HDF
High-efficiency post-dilution online hemodiafiltration (OL-HDF) using high-flux dialyzer and requiring high blood flow rate (BF ≥400 mL/min) has been reported to enhance protein-bound toxin and middle molecular toxin removal and…
- Trial name
- NCT03288922
- Testing
- Limited BF OL-HDF with SHF, High-efficiency OL-HDF
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Chulalongkorn University
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