Clinical trials: End Stage Disease
Iron Deficiency Anemia, Chronic Liver Failure
Lactoferrin in Treatment of Fe Deficient Anemia In Cirrhosis
Iron deficiency and altered homeostasis due to inflammation and decreased iron utilization are main factors involved in anemia in liver disease.
- Trial name
- NCT04335058
- Testing
- Lactoferrin + Iron Supplement, Iron Supplement
- Where
- India
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
End-Stage Kidney Disease, Renal Dialysis
The Impact of Different Citrate Concentrations as Locking Solutions on Development of Biofilm and Function of Hemodialysis Catheters
Evidence that supports using certain concentration of trisodium citrate as a locking solution for hemodialysis catheters has not yet been established.
- Conditions
- End-Stage Kidney Disease, Renal Dialysis, Central Venous Catheter, Biofilms
- Trial name
- NCT03683563
- Testing
- 4% sodium citrate, 30% sodium citrate
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
Heart Failure, Congenital
Etablishment of Follow-up System and End-Stage Heart Registration Platform for Pediatric Heart Failure
Establish a follow-up management system for pediatric heart failure and a registration platform for end-stage heart failure
- Conditions
- Heart Failure, Congenital, End-stage Heart Failure
- Trial name
- NCT06345521
- Testing
- No intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hepatitis C, Chronic
An Extension Study to Evaluate the Safety and Efficacy of Celgosivir and Peginterferon Alfa-2b, With or Without Ribavirin, in Patients With Chronic Hepatitis C Genotype 1 Infection
This is an extension study of HCV-05-002. The objective of this study is to evaluate the safety and efficacy of celgosivir plus peginterferon alfa-2b, with or without ribavirin, for an additional 36 weeks in patients with chronic…
- Trial name
- NCT00292084
- Testing
- Celgosivir
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- BioWest Therapeutics Inc
End Stage Renal Disease
Transplant Navigator Intervention to Overcome Barriers to Kidney Transplantation
Compared with chronic dialysis treatment, kidney transplantation generally offers a longer life span, a better quality of life, and lower health care costs for the over 500,000 Americans with End Stage Renal Disease.
- Trial name
- NCT00805038
- Testing
- Transplant navigator, Usual care
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- Case Western Reserve University
End Stage Renal Disease
A Study of Drug-Induced Kidney Disease
The purpose of this study is to identify incidence of Chinese herb nephropathy in a medical center
- Trial name
- NCT00729014
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
End-Stage Kidney Disease, Type 2 Diabetes Mellitus
Glucose Containing and Glucose Free Hemodialysate in Type 2 Diabetic Patients
The purpose of this study is to investigate differences in glycemia during the whole hemodialysis day and the whole freeday during hemodialysis, during the evening and the night after hemodialysis and at the same time intervals…
- Trial name
- NCT02009514
- Testing
- Glucose-containing compared to glucose-free hemodialysate
- Volunteers
- 10 people
- Sponsor
- Tampere University Hospital
Arteriovenous Fistula
Effects of Heparin on Arteriovenous Fistula Patency
Arteriovenous fistula (AVF) is now the optimal method of obtaining vascular access for dialysis. Measures such as systemic anticoagulation have been proposed as means of increasing patency rates but enough evidence does not exist…
- Trial name
- NCT02493504
- Testing
- Heparin
- Volunteers
- 150 people
- Sponsor
- Fatemeh Hoseinzadegan
End Stage Renal Disease
Native Kidney Denervation in Patients With End Stage Renal Disease
To investigate the utility of renal denervation in the treatment of patients with End Stage Renal Disease (ESRD).
- Trial name
- NCT00551304
- Testing
- Ardian Catheter
- Where
- 2 sites in Australia, Poland
- Sponsor
- Medtronic Vascular
Anemia, Renal Failure, Chronic Renal Failure
Effects of Early Correction of Anemia in Patients With Chronic Renal Insufficiency
The purpose of the study is to assess the effect of an early and complete correction of anemia after treatment with epoetin alfa on the rate of progression of chronic renal failure (which involves improper functioning of the…
- Trial name
- NCT00312871
- Testing
- Epoetin alfa
- Volunteers
- 217 people
- Sponsor
- Janssen Cilag S.A.S.
End Stage Renal Disease
Virtual Reality Versus Conventional Exercise Intradialysis
All participants exercised during 16 weeks following a conventional intradialysis exercise program. The last 4 weeks of the study participants were randomized into two different exercise programs intradialysis.
- Trial name
- NCT03120611
- Testing
- Virtual Reality Exercise, Conventional exercise intradialysis
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Cardenal Herrera University
Knee Osteoarthritis, Arthrogenic Muscle Inhibitions
Effect of Action Observation and Motor Imagery on Arthrogenic Muscle Inhibition of the Quadriceps in Patients With End-stage Knee Gonarthrosis.
The study aims at evaluating the effects of one session of Action Observation Training (AOT) and Motor Imagery (MI) on arthrogenic muscle inhibition (AMI) of the quadriceps (QF) in subjects with end-stage gonarthrosis.
- Trial name
- NCT06000345
- Testing
- AOT + MI, Control AOT + MI
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Clinico Humanitas
End-Stage Renal Disease Requiring Haemodialysis, Mobile Application
Evaluation of the Effectiveness of a Mobile Application Developed for Hemodialysis Patients.
This study aims to evaluate the effectiveness of a mobile health application developed for adult patients undergoing hemodialysis treatment.
- Trial name
- NCT07211100
- Testing
- Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Saglik Bilimleri Universitesi
End Stage Renal Disease
Pharmacokinetics and Optimal Dose of Ertapenem in Hemodialysis Patients
The purpose of this study is to determine the amount of ertapenem in the blood over time between hemodialysis session.
- Trial name
- NCT02159859
- Testing
- Ertapenem
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Corewell Health East
End Stage Liver Disease, Impaired Renal Function
CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal Impairment
Background: Patients undergoing liver transplantation with preexisting renal dysfunction are prone to further renal impairment with the early postoperative use of Calcineurin-inhibitors.
- Trial name
- PATRON07 (NCT00604357)
- Testing
- anti-CD 25 mAb, Sirolimus, MMF
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- University of Regensburg
Cardiovascular Diseases, Kidney Failure, Chronic
Pharmacokinetics of Dabigatran Etexilate (Pradaxa®) During Haemodialysis
The current study will allow the assessment of pharmacokinetics, pharmacodynamics, elimination rate and clearance of dabigatran etexilate during and following haemodialysis in ESRD patients.
- Trial name
- NCT01241539
- Testing
- Dabigatran etexilate
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Boehringer Ingelheim
End Stage Renal Disease
Peridialysis Project: The Influence of Predialysis Factors on the Initial Course of Dialysis
The present study plans to delineate the clinical, biochemical, sociological and psychological factors. involved in dialysis preparation, and their impact on dialysis initiation (DI), modality choice and prognosis.
- Trial name
- Peridialysis (NCT02488200)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 1,400 people
- Sponsor
- Herlev Hospital
Anemia, End Stage Renal Disease
Epodure Therapy of Anemia in End Stage Renal Disease on Dialysis With Epodure Skin Implant
In this End Stage Renal Disease (ESRD) patients who need Erythropoietin (epo) hormone will get it by a small implant of skin using their own skin, the implant will be treated in the laboratory and programmed to secrete Epo.
- Trial name
- NCT01555515
- Testing
- implantation of autologous skin graft after ex-vivo treatment, Subcutan implantation of autologus skin graft after ex-vivo treatment
- Volunteers
- 4 people
- Sponsor
- Medgenics Medical Israel Ltd.
End Stage Liver DIsease
SALT in Adolescents With End-stage Liver Disease
End-stage liver disease is synonymous with advanced liver disease, liver failure, and decompensated cirrhosis, and their disease progression is generally irreversible.
- Trial name
- NCT06069050
- Testing
- sequential adolesent left lateral lobe liver transplantation (SALT)
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Anemia, End Stage Renal Disease
Artificial Intelligence for Optimal Anemia Management in End-stage Renal Disease: The Anemia Control Model (ACM) Trial
Fresenius Medical Care has developed a computer software programme called the Anaemia Control Management (ACM) software to assist in the anaemia management of patients with chronic kidney disease (CKD) undergoing hemodialysis.
- Trial name
- ANEMEX (NCT03214627)
- Testing
- Anemia Control Model (ACM), IV iron, Erythropoiesis-Stimulating Agent (ESA)
- Where
- United Kingdom
- Volunteers
- 88 people
- Sponsor
- Vifor Fresenius Medical Care Renal Pharma
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