Clinical trials: End Stage Renal Diseases
Kidney Failure, Chronic
Randomized Study of Recombinant Human Growth Hormone in Patients on Chronic Hemodialysis or Peritoneal Dialysis
OBJECTIVES: I. Assess the clinical safety and long term effects of recombinant human growth hormone on a defined range of nutritional indices in malnourished chronic hemodialysis and continuous ambulatory peritoneal dialysis…
- Trial name
- NCT00004429
- Testing
- growth hormone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- FDA Office of Orphan Products Development
End Stage Renal Disease
Clinical Outcomes and Costs of 4-Week Versus 6-Week Bloodwork for Patients on Hemodialysis
The objective of this quality improvement study was to determine the effect of an institution-wide switch of routine bloodwork from four-week intervals to six-week intervals on the achievement of anemia and chronic kidney…
- Trial name
- NCT03659500
- Testing
- Four-week routine bloodwork, Six-week routine bloodwork
- Volunteers
- 400 people
- Sponsor
- Samuel Silver
Restless Legs Syndrome, End Stage Renal Disease
The Effect of Vitamin C and E Therapy on Restless Leg Syndrome in Patients With End Stage Renal Disease on Haemodialysis
This study aims to measure the effectiveness of vitamins C and E on relieving RLS symptoms in end stage renal disease patients on HD
- Trial name
- NCT05350124
- Testing
- Ascorbic acid, Tocopherol
- Volunteers
- 160 people
- Sponsor
- King Abdulaziz University
End Stage Renal Disease, Kidney Failure
Virtual Ward for Home Dialysis
Home based renal replacement therapy (RRT), including peritoneal dialysis (PD) and home hemodialysis(HHD), offers enhanced quality of life and clinical advantages compared to conventional in-center hemodialysis.
- Conditions
- End Stage Renal Disease, Kidney Failure, Home Dialysis
- Trial name
- Virtual Ward (NCT01912001)
- Testing
- Telephone follow-up, Sympton Assessment
- Where
- 7 sites in Canada
- Volunteers
- 215 people
- Sponsor
- Christopher Chan
End-Stage Renal Disease, Hemodialysis Complication
The Effect of Intradialytic Exercise on Postural Abnormalities
This randomized, assessor-blinded controlled trial will evaluate the preliminary efficacy and safety of a 12-week supervised intradialytic multimodal exercise program for improving postural abnormalities in adults receiving…
- Trial name
- NCT07720401
- Testing
- Supervised Intradialytic Multimodal Exercise Program
- Where
- Iran
- Volunteers
- 98 people
- Sponsor
- Pardis Specialized Wellness Institute
Kidney Transplantation
Noninvasive Methods to Monitor Graft Survival in Kidney Transplant Patients
The purpose of this study is to test noninvasive methods to monitor the health and condition of new kidneys in people who have received kidney transplants.
- Trial name
- NCT00308802
- Testing
- Kidney transplantation
- Where
- 9 sites in United States, Canada
- Volunteers
- 280 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Erythropoietin Resistant Anemia (EPO Resistant Anemia)
" Evaluation of Erythropoietin Therapy in Patients With End-Stage Kidney Disease on Regular Hemodialysis: Hemoglobin Outcomes, and Metabolic Syndrome as a Risk Factor for Erythropoietin Resistance "
The primary aim of this study is to investigate the association between metabolic syndrome and erythropoietin resistance in patients with End-Stage Kidney Disease (ESKD).
- Trial name
- NCT06983756
- Testing
- Erythropoietin
- Volunteers
- 66 people
- Sponsor
- Fayoum University
Heart Failure, End Stage Renal Disease
Soluble Neprilysin, NT-proBNP, and Growth-Differentiation-Factor-15 as Biomarkers for Heart Failure in Dialysis Patients
Objectives: The aim of this study is to determine whether growth differentiation factor-15 (GDF15) and circulating neprilysin (cNEP) improve the diagnosis of congestive heart failure (HF) in patients on dialysis.
- Trial name
- SONGBIRD (NCT04061811)
- Testing
- Diagnostic biomarker study
- Where
- 2 sites in France, Germany
- Volunteers
- 153 people
- Sponsor
- Hannover Medical School
End-Stage Kidney Disease, Hemodialysis
A Prospective, Multi-center Registry to Evaluate Safety and Efficacy of Hativ® ELectrocardiogram Monitoring on Patients with Hemodialysis
The high mortality rate and costs of patients with end-stage renal disease (ESRD) are a medical and socio-economic burden, so managing their risk factors is very important.
- Trial name
- NCT06688565
- Testing
- Hativ® electrocardiogram monitoring
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Hallym University Medical Center
End-Stage Kidney Disease
Adding Receptive Music to Intradialytic Resistance Exercise in Adults Receiving Maintenance Hemodialysis
People receiving maintenance hemodialysis commonly experience reduced physical function and exercise capacity. Intradialytic resistance exercise may help preserve or improve physical function, while receptive music listening may…
- Trial name
- NCT07819331
- Testing
- Intradialytic Resistance Exercise, Receptive Music Listening
- Where
- Tunisia
- Volunteers
- 47 people
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Chronic Renal Disease, Cardiovascular Disease
Dyslipidemia-related Risk Factors in Dialysis
In this study, we studied lipoprotein abnormalities-related variables as risk factors for the development of cardiovascular disease in patients on renal replacement therapies.We studied 96 dialyzed patients, 62 males and 34…
- Conditions
- Chronic Renal Disease, Cardiovascular Disease, Dyslipidemia
- Trial name
- NCT02072837
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
End Stage Renal Disease (ESRD)
Effect of Medium Cut-Off Hemodialysis on Protein Energy Wasting: The EMCOPEW Study
In patients on maintenance hemodialysis (HD), protein energy wasting (PEW) defined as loss of muscle mass and fuel reserves of the body is frequent and associated with severe morbidity and mortality.
- Trial name
- EMCOPEW (NCT05309109)
- Testing
- Hemodialysis sessions
- Where
- 2 sites in France
- Volunteers
- 65 people
- Sponsor
- Poitiers University Hospital
End Stage Renal Disease
Efficacy and Safety of XyloCore Peritoneal Dialysis Solution.
Randomized, controlled, parallel groups, open-label, blinded end-point assessment, multicenter study, comparing the effects of a low glucose peritoneal dialysis solution, XyloCore, to glucose solutions (Physioneal, Fixioneal…
- Trial name
- ELIXIR (NCT03994471)
- Testing
- XyloCore Low Strenght, XyloCore Medium Strenght, XyloCore High Strenght, 1.36%, 1.5%, 2.27%, 2.5%, 3.86%, 2.25% Glucose PD Solution
- Where
- 41 sites in Denmark, Germany and 4 more
- Volunteers
- 170 people
- Sponsor
- Iperboreal Pharma Srl
End Stage Renal Disease
Association of Middle Molecules Clearance With HDF Volume
HDF is a dialysis technique which involves diffusion and convection. HDF with high convection volume has consistently shown to improve survival in dialysis patients in number of robust RCTs.
- Trial name
- NCT06515899
- Where
- United Kingdom
- Volunteers
- 342 people
- Sponsor
- East and North Hertfordshire NHS Trust
End Stage Renal Disease
Effect of Lanthanum Carbonate in Patients Previously Treated With Calcium-based Phosphate Binder Therapy
To assess the percentage of patients on lanthanum carbonate, that achieve Kidney Disease Outcome Quality Initiative (KDOQI) guideline suggested values for serum phosphorous in patients previously treated with calcium-based…
- Trial name
- NCT01130831
- Testing
- Lanthanum carbonate
- Where
- 31 sites in Germany
- Volunteers
- 66 people
- Sponsor
- Shire
Chronic Kidney Failure, Secondary Hyperparathyroidism
Follow-up Patients With End Stage Renal Disease Receiving Zemplar to Prevent and Treat Secondary Hyperparathyroidism
The aim of this post-marketing observational study is to obtain further data on the long term use, safety and efficacy of Zemplar as it is prescribed in the normal clinical setting and according to the approved Summary of Product…
- Trial name
- NCT01081665
- Where
- 19 sites in Greece
- Volunteers
- 237 people
- Sponsor
- Abbott
End Stage Renal Disease, AV Fistula
Percutaneous Less Invasive AV Fistula for Vascular Access in ESRD
A prospective single-arm well-controlled study to evaluate the safety and effectiveness of a less invasive means of establishing vascular access to facilitate dialysis in patients with end stage renal disease.
- Conditions
- End Stage Renal Disease, AV Fistula, Fistula, End Stage Kidney Disease
- Trial name
- NCT02363972
- Testing
- Ellipsys Vascular Access Catheter
- Where
- 5 sites in United States
- Volunteers
- 103 people
- Sponsor
- Medtronic Endovascular
Endstage Renal Disease
The Effect of Increasing Dialysate Magnesium on Calcification Propensity in Subjects on Haemodialysis
The purpose of this trial is to examine the effect of increasing dialyse magnesium on serum calcification propensity in subjects with end-stage renal disease treated with haemodialysis.
- Trial name
- NCT02977117
- Testing
- Dialysate magnesium (1.0 mmol/L), Dialysate magnesium (0.5 mmol/L)
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- Iain Bressendorff
Hyperparathyroidism, Kidney Disease
Safety and Efficacy Study of Paricalcitol Versus Calcitriol in the Treatment of Secondary Hyperparathyroidism
The purpose of this study is to determine whether oral paricalcitol is safer and more efficacious compared to oral calcitriol in the treatment of hyperparathyroidism in chronic kidney disease patients undergoing dialysis.
- Trial name
- NCT00800358
- Testing
- Paricalitol, Calcitriol
- Where
- 11 sites in Malaysia
- Volunteers
- 69 people
- Sponsor
- Penang Hospital, Malaysia
End Stage Renal Disease, Hemodialysis
Effects of On-Line Hemodiafiltration(HDF) on Vascular Health in Chronic Hemodialysis Patients
The purpose of this study is to determine whether on-line hemodiafiltration ameliorate the endothelial dysfunction compared with the low flux hemodialysis in end stage renal disease patients on maintenance hemodialysis.
- Trial name
- NCT00532597
- Testing
- On-line hemodiafiltration, Low flux hemodialysis
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Eulji General Hospital