Clinical trials: End Stage Renal Diseases
End Stage Renal Failure
Registry for End Stage Renal Failure
The rein registry collects case record data from patients with end stage renal disease followed in French Guiana. This allows to generate incidence and rates for terminal renal disease, mortality rates for each territory.
- Trial name
- REIN (NCT02895425)
- Testing
- Registry (No intervention)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier de Cayenne
Chronic Kidney Disease, Hypertension
ADMA Levels in End-Stage Renal Disease
Asymmetric dimethylarginine, ADMA, in plasma, is significantly elevated in patients with renal disease and associated with cardiovascular morbidity and mortality.
- Trial name
- NCT00350974
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Michigan
End-stage Chronic Kidney Disease Treated With Hemodialysis, Depressive Disorders
Evaluation of the Effect of Light Therapy on the Evolution of Self-reported Depressive Disorders in Chronic Hemodialysis Patients
Hemodialysis is an intensive treatment, with a lifestyle dictated by the organization of the dialysis center. This treatment is associated with a decrease in quality of life, an increase in sleep disorders, and depressive…
- Trial name
- LUMIDIAL-2 (NCT07729358)
- Testing
- Light therapy using active glasses, Light therapy using inactive glasses
- Where
- France
- Volunteers
- 340 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Renal Insufficiency, Kidney Diseases
Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB054707 in Participants With Normal and Impaired Renal Function and Participants on Hemodialysis
This is a multi-center, open-label, parallel-group study to evaluate oral doses of INCB054707 in participants with varying levels of renal function or impairment.
- Trial name
- NCT05624723
- Testing
- INCB054707
- Where
- 2 sites in United States, Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Incyte Corporation
End Stage Kidney Disease
Investigation of Performance and Compatibility of the Baxter Dialyzer Xenium XPH 210 During On-line Hemodiafiltration
The proposed study seeks to determine the appropriate balance between the removal of undesirable small molecular substances (urea, creatinine, phosphate) and large molecular substances (ß2-m) and the retention of important…
- Trial name
- NCT00976846
- Testing
- Dialyzer Baxter Xenium XPH 210
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- Praxisverbund Dialyse und Apherese
End Stage Renal Disease on Dialysis
AQP-1 Polymorphism on Fluid Status in Hemodialysis Patients
It is a cross sectional observational study. It is to investigate whether AQP-1 polymorphism has any impact on fluid status in hemodialysis patients.
- Trial name
- NCT05275387
- Testing
- observational study, no intervention
- Where
- China
- Volunteers
- 250 people
- Sponsor
- RenJi Hospital
Primary IgA Nephropathy
The Effect of Nefecon® in Patients With Primary IgA Nephropathy at Risk of Developing End-stage Renal Disease
The objective of the study is to evaluate efficacy and safety of two different doses of NEFECON in the treatment of patients with primary IgA nephropathy (IgAN) at risk of developing end-stage renal disease, under rigorous blood…
- Trial name
- NEFIGAN (NCT01738035)
- Testing
- NEFECON
- Where
- 58 sites in Belgium, Czechia and 8 more
- Volunteers
- 150 people
- Sponsor
- Calliditas Therapeutics AB
End-Stage Renal Disease
Morbidity, Mortality, Short and Long-term Survival of Hemodialysis End-stage Kidney Disease Patients in Central Tanzania
Background: In the last 2 decades, Tanzania made great improvements in the renal replacement therapy infrastructure and services.
- Trial name
- NCT03988491
- Where
- Tanzania
- Volunteers
- 10,000 people
- Sponsor
- Benjamin Mkapa Hospital
End Stage Renal Disease
Effects of Exercise and Improved Nitric Oxide Bioavailability on Arteriovenous Fistula Maturation
This project will examine if enhancing Nitric Oxide (NO) bioavailability increases the rates of arteriovenous fistula (AVF) maturation in end stage renal disease patients requiring vascular access for hemodialysis.
- Trial name
- NCT02164318
- Testing
- Handgrip training, Nitroglycerin ointment
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Duke University
End Stage Renal Disease on Dialysis (Diagnosis)
Comparison of High-Flow Hemodialysis Catheters Placed From the Left Internal Jugular Vein(R12-022)
The patient population for this study is individuals requiring high-flow polyurethane tunneled dialysis catheters (TDC) for hemodialysis access.
- Trial name
- NCT03523260
- Testing
- Tunneled dialysis catheter placement.
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
End-Stage Kidney Disease
Biological Determinants of Peritoneal Dialysis
Peritoneal Dialysis (PD) is a technique for treating kidney failure where fluid is instilled into the body's peritoneal cavity. Fluid and solutes travel across the peritoneal membrane, and the function of this membrane is…
- Trial name
- Bio-PD (NCT02694068)
- Testing
- Peritoneal Equilibrium Test, 4 hour dwell of 2.5/4.25% dextrose solution
- Where
- United States
- Volunteers
- 4,865 people
- Sponsor
- University of Washington
Chronic Kidney Diseases, Renal Disease
Pain Relief Intervention of Meditation in Renal Disease (PRIMER)
Kidney Disease subjects will be recruited to take part of a mindfulness-based stress reduction intervention for 8-10 sessions. All subjects will complete a baseline interview, one follow-up at 3 months and the close out interview…
- Conditions
- Chronic Kidney Diseases, Renal Disease, Chronic Kidney Failure, End Stage Renal Disease
- Trial name
- PRIMER (NCT03161197)
- Testing
- Mindfulness-Based Stress Reduction
- Volunteers
- 24 people
- Sponsor
- Weill Medical College of Cornell University
End Stage Renal Disease
Confirmatory Study to Assess the V Needle in End-Stage Renal Disease Patients During In-Clinic Hemodialysis
This study is a prospective, multi-center, single-arm study with subjects acting as their own control designed to confirm the safety, performance, and usability of the V Needle, a new safety needle for use during in-clinic…
- Trial name
- Clinic-SAVER (NCT05493423)
- Testing
- V Needle AV Fistula Set
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Hemotek Medical Inc
Chronic Kidney Disease
Evaluation of the Effect of a Daily Dose of Wakame Seaweed on Reducing Circulating Concentrations of Advanced Glycation End Products in Patients With Stage III Chronic Kidney Disease
Persistent glomerular hyperfiltration is a characteristic feature of the early stages of kidney disease and represents a factor in the progression of chronic kidney disease (CKD).
- Trial name
- Ckd-WEED (NCT07729683)
- Testing
- Consumption of wakame
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
End Stage Renal Disease
Complementary Intradialytic Nutritional Supplementation in Dialysis Patients
In this study, the investigators hypothesize that long-term administration of adequate intradialytic oral nutritional supplementation will increase visceral protein concentrations and somatic protein stores in malnourished…
- Trial name
- NCT00179205
- Testing
- Nepro nutritional supplement
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Vanderbilt University
Chronic Kidney Disease, End-stage Renal Disease
MONITOR-CKD5 - Multi-level Evaluation of Anaemia Treatment, Outcomes, and Determinants in Chronic Kidney Disease Stage 5
MONITOR-CKD5 is an observational, pharmaco-epidemiological study to evaluate the multi-level factors and outcomes associated with the treatment of renal anaemia with biosimilar epoetin alfa in Stage 5 CKD patients requiring…
- Conditions
- Chronic Kidney Disease, End-stage Renal Disease, Anaemia
- Trial name
- MONITOR-CKD5 (NCT01121237)
- Testing
- Recombinant human erythropoietin alfa (biosimilar)
- Where
- 95 sites in Austria, France and 8 more
- Volunteers
- 2,086 people
- Sponsor
- Sandoz
Arteriovenous Fistula
Dexmedetomidine and Propofol As Sole Sedative Agent for Patients Undergoing Arteriovenous Fistula Surgery
The investigators designed a prospective randomized study to compare the conventionally used sedative drug propofol with a latest alternative dexmedetomidine (DEX), in patients with end-stage renal disease undergoing…
- Trial name
- NCT02447796
- Testing
- Propofol, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Primary Amyloidosis of Light Chain Type
High Cut-off Hemodialysis in Patients With Advanced Cardiac AL Amyloidosis and End Stage Renal Disease
The aim of the study is to assess survival of patients with advanced cardiac AL amyloidosis treated with high cut-off hemodialysis (HCO-HD) combined with chemotherapy.
- Trial name
- DIACAL (NCT01531751)
- Testing
- High Cut-off Hemodialysis, Chemotherapy
- Where
- Italy
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
End-Stage Renal Disease, Dialysis
Effects of N-acetylcysteine on Muscle Fatigue in Hemodialysis
The purposes of the study are to determine whether oxidative stress causes the muscle of dialysis patients to tire more quickly than muscle of people without kidney disease and to determine whether treatment with…
- Conditions
- End-Stage Renal Disease, Dialysis, Hemodialysis
- Trial name
- NAC (NCT00440869)
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
End-stage Renal Disease, Kidney Failure, Chronic
Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With End-Stage Renal Disease
The purpose of this study is to assess the safety and efficacy of a novel, tissue-engineered vascular prosthesis, the Human Acellular Vascular Graft, HAVG.
- Trial name
- NCT01840956
- Testing
- HAVG
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Humacyte, Inc.
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