Clinical trials: End Tidal Carbon Dioxide
Hypercapnic Respiratory Failure
Use of EtCO2 as a PaCO2 Predictor Under Non Invasive Ventilation (NIV) in Cases of Acute Hypercapnic Respiratory Failure
In patients treated by Non invasive ventilation (NIV) due to acute hypercapnic respiratory failure, the interest of using the End-tidal Co2 measurement device "Capnostream" to evaluate PaCo2 and PaCo2 variations over time will be…
- Trial name
- NCT01489150
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University of Lausanne Hospitals
Video-Assisted Thoracoscopic Surgery, One-Lung Ventilation
Trending Ability of End-Tidal Capnography to Reflect Arterial Carbon Dioxide Changes in One-Lung Ventilation
In this study, we want to find out if measuring carbon dioxide from a patient's breath (end-tidal CO₂ or ETCO₂) can reliably reflect changes in blood carbon dioxide levels (arterial CO₂ or PaCO₂) during lung surgery.
- Conditions
- Video-Assisted Thoracoscopic Surgery, One-Lung Ventilation, Capnography, Blood Gas Analysis
- Trial name
- NCT06835894
- Volunteers
- 115 people
- Sponsor
- Koç University
End-tidal Sevoflurane, End-tidal Carbon Dioxide
Etco2 Levels on the End-tidal Concentration of Sevoflurane
he assessment of adequate levels of anaesthesia traditionally relies not only on a patient's movement but also on the hemodynamic response (or both) to a surgical stimulus
- Conditions
- End-tidal Sevoflurane, End-tidal Carbon Dioxide, Minimum Alveolar Concentration
- Trial name
- NCT05778968
- Testing
- low etco2, normal etco2, high etco2
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Acute Respiratory Failure
Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults
This study will compare the sensitivity and specificity of waveform capnography versus colorimetric carbon dioxide detection to identify tracheal placement of the endotracheal tube during intubation of critically ill adults.
- Trial name
- WAVE (NCT06934876)
- Testing
- Colorimetric carbon dioxide (CO2) detection, Waveform capnography
- Where
- 9 sites in United States
- Volunteers
- 2,092 people
- Sponsor
- Brian Driver
Ventilation Perfusion Mismatch
Effect of Patient Position on Arterial, End-tidal and Transcutaneous Carbon Dioxide
Investigators evaluate the effect of patient position (Trendelenburg and reverse Trendelenburg) on arterial, end-tidal and transcutaneous carbon dioxide partial pressure in patients undergoing laparoscopic surgery.
- Trial name
- NCT03508791
- Testing
- Arterial carbon dioxide monitoring, End-tidal carbon dioxide monitoring, Transcutaneous carbon dioxide monitoring
- Volunteers
- 142 people
- Sponsor
- SMG-SNU Boramae Medical Center
Lung Cancer (Diagnosis), Lobectomy
Simplified Exercise-based Risk Assessment in Lung Cancer
Physiological evaluation is part of the preoperative risk estimation in patients with lung cancer, and it aids in the choice of treatment.
- Conditions
- Lung Cancer (Diagnosis), Lobectomy, Surgery Complications, Neoadjuvant Chemoimmunotherapy
- Trial name
- EXHALE-CO2 (NCT07506889)
- Where
- 5 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Linkoeping University
Acute Kidney Injury, Ventilated Patient in Intensive Care
The Value of Partial Arterial Carbon Dioxide Pressure - End-Tidal Carbon Dioxide Gradient Courses in Predicting Acute Renal Injury in Critically Ill Patients on Mechanical Ventilation: A Novel Hemodynamic Marker?
End-tidal carbon dioxide (EtCO₂) refers to the level of carbon dioxide in the air exhaled during expiration and is measured using capnography.
- Trial name
- NCT07654010
- Where
- Turkey (Türkiye)
- Volunteers
- 155 people
- Sponsor
- Malatya Egitim Ve Arastirma Hastanesi
Pneumothorax
The Diagnostic Value of End-Tidal CO2 in Patients Diagnosed With Pneumothorax
Pneumothorax (PTX) is defined as the accumulation of air in the pleural space. PTX can cause a disruption in the perfusion of lung tissue in the affected area and increase intrathoracic pressure, potentially leading to…
- Trial name
- NCT06276751
- Testing
- End-tidal CO2 monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Ankara City Hospital Bilkent
Preload Responsiveness, Fluid Responsiveness
Study of End Tidal Carbon Dioxide (EtCO2) Variation After an End- Expiratory Occlusion Test as a Predictive Criteria of Fluid Responsiveness in Mechanically Ventilated Patients
Hypovolemia is one of major factor of haemodynamic instability. Fluid administration is not totally riskless. Indeed, it can create or inflate pulmonary oedema, alter gaz exchanges and increase post operative respiratory…
- Trial name
- CapnoPause (NCT04889807)
- Testing
- measure of EtCO2 variation
- Where
- France
- Volunteers
- 41 people
- Sponsor
- CHU de Reims
COPD
End Tidal Carbon Dioxide Monitoring for Evaluating Changes of PaCO2 After Noninvasive Mechanical Ventilation in COPD
Sidestream end-tidal CO2 has been found to be closely correlated to PaCO2 especially when people have the stable hemodynamics and normal lung function.
- Trial name
- NCT01821365
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Anesthesia, Carbon Dioxide
EtCO2 Level to Control Intraoperative Bleeding and Improve the Quality of Surgical Field Vision in Septorhinoplasty
It is unknown whether different end-tidal carbon dioxide pressure levels have a clinically significant effect on bleeding and surgical field quality in septorhinoplasty, especially during controlled hypotension.
- Conditions
- Anesthesia, Carbon Dioxide, Surgical Blood Loss
- Trial name
- EtCO2 (NCT05497375)
- Testing
- The amount of intraoperative bleeding, Quality of the intraoperative surgical field, Surgeon Satisfaction
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bezmialem Vakif University
Fluid Responsiveness
Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness
In the critically ill population, fluid administration in an unstable patient is perhaps the most common intervention that is performed.
- Trial name
- PHOENIX (NCT06390423)
- Testing
- Passive leg raise, SVI via bioreactance, Echo based VTI
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- CentraCare
Capnography
The Effect of Oxygen Flow Rate on End-tidal CO2 During Deep Sedation
This study aims to detect the effect of different O2 flow rates on end tidal carbon dioxide level in patients scheduled for minor gynaecological procedures under deep sedation using laryngeal mask airway.
- Trial name
- NCT06824610
- Testing
- capnography
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Minia University
Invasive Mechanical Ventilation, Ventilation-Perfusion Mismatch
Physiological Dead Space and Intensive Care Mortality in Mechanically Ventilated Patients
This study investigates the relationship between physiological dead space and clinical outcomes, specifically mortality and discharge status, in adult patients receiving invasive mechanical ventilation in the intensive care unit…
- Conditions
- Invasive Mechanical Ventilation, Ventilation-Perfusion Mismatch, ICU Mortality, Critical Illness
- Trial name
- IRIS-MAP (NCT06963944)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Karadeniz Technical University
Out-Of-Hospital Cardiac Arrest
EXecution of Trans-Esophagus Echo Cardiogram in CardioPulmonary Resuscitation for Patients With Out-of-hospital Cardiac Arrest
The purpose of this single center, randomized clinical control trial is to determine that changing chest compression site during cardiopulmonary resuscitation according to the examination of the TEE could increase the level of…
- Trial name
- EXECT_CPR (NCT05907460)
- Testing
- transesophageal echocardiography examination during cardiopulmonary resuscitation
- Where
- Taiwan
- Volunteers
- 132 people
- Sponsor
- Far Eastern Memorial Hospital
Carbon Dioxide
Non Invasive End Tidal Carbon Dioxide Monitoring During Moderate Sedation
CO2 monitoring through non-invasive methods at different O2 flow rates may provide an early warning sign of hypoventilation during procedural sedation.
- Trial name
- EtCO2 (NCT04588272)
- Testing
- DualGuard
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Anesthesia, General, Infant
Impact of CO2 on Cerebral Blood Flow in Infants Less Than 6 Months During General Anaesthesia
The study aims at assessing cerebral blood flow variations following expired CO2 variations in anaesthetized infants less than 6 months, during a routine general anesthesia.
- Trial name
- NCT03567031
- Testing
- EtCO2 modification
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Propofol-anaesthesia Via Target-controlled Infusion
The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia
Purpose: The purpose of this study is to examine the effect of different carbon-dioxide concentrations on cerebral CO2 sensitivity and the resistance and stiffness of systemic arteries during anesthesia with target-controlled…
- Trial name
- NCT02203097
- Testing
- Partial pressure of CO2 at the end of an exhaled breath, Propofol
- Where
- Hungary
- Volunteers
- 25 people
- Sponsor
- University of Debrecen
Idiopathic Intracranial Hypertension
The Effects of MAP and EtCO2 on Venous Sinus Pressures
The purpose of this study is to further elaborate the role of both arterial blood pressure and end-tidal carbon dioxide concentration on measured venous pressures.
- Trial name
- NCT03867461
- Testing
- Venous Sinus Stenting, Adjustment to end-tidal carbon dioxide concentrations ( 38-40 mmHg range), Adjustment to Mean Arterial Pressure (100-110 mmHg range)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Wake Forest University Health Sciences
Cognitive Dysfunction
The Influence of Ventilation on Perioperative Neurocognitive Disorders
This prospective study is designed to examine the influence of intra-operative ventilation on perioperative neurocognitive disorders in patients undergoing total hip arthroplasty.
- Trial name
- NCT04106869
- Testing
- Hyperventilation, Hypoventilation
- Where
- Belgium
- Sponsor
- Université Libre de Bruxelles