Clinical trials: End of Life Care
Pregnancy, Postpartum
Organ Dysfunction Score for Obstetric Patients
The goal of this observational study is to develop and evaluate an organ dysfunction score adapted to pregnancy and early puerperium (SOFA-OBS) that also incorporates a non-invasive tool to evaluate respiratory function (pulse…
- Conditions
- Pregnancy, Postpartum, Organ Dysfunction, Critical Care, Intensive Care
- Trial name
- SOFA-OBS (NCT07068022)
- Testing
- Organ dysfunction score adjusted to obstetric patients (SOFA-OBS)
- Where
- 18 sites in Argentina, Ecuador and 2 more
- Volunteers
- 130 people
- Sponsor
- Daniela Vasquez
End-of-life, Diabetes
Diabetes and Palliative Care
Diabetes prevalence in palliative care is 10-15%. Most hospice patients are treated with insulin. The target glucose level is high in order to decrease the risk of hypoglycemia.
- Conditions
- End-of-life, Diabetes, Terminal Cancer
- Trial name
- DIAPAL (NCT02742701)
- Testing
- diagnosis
- Volunteers
- 180 people
- Sponsor
- Maison Médicale Jeanne Garnier
Depression
Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
KetaPal is a placebo-controlled randomized trial designed to demonstrate the antidepressant action of ketamine in palliative care situations.
- Trial name
- KETAPAL (NCT02783430)
- Testing
- Ketamine, Milnacipran
- Where
- 9 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Lille
Fetal Death, Fetal Anomaly
Antenatal Palliative Care
In France, according to current legislation, termination of pregnancy could be performed without any upper gestational age limit, if there is a strong probability that the fetus will be affected by a particularly severe and…
- Trial name
- SPAN (NCT03795857)
- Testing
- Semi-structured interviews
- Where
- 3 sites in France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cancer
Early Intervention vs. Standard Palliative Care in Improving End-of-Life Care in Advanced Cancer Patients
RATIONALE: Palliative care may help patients with advanced cancer live more comfortably. PURPOSE: This randomized clinical trial is studying an early intervention palliative care program to see how well it works compared to a…
- Trial name
- NCT00253383
- Testing
- counseling intervention, educational intervention, psychosocial assessment and care
- Where
- 2 sites in United States
- Volunteers
- 329 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms
- Trial name
- PICSI-H (NCT04283994)
- Testing
- Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 756 people
- Sponsor
- University of Washington
Palliative Care, Disclosure
Increasing the Number of Patients Receiving Information About Transition to End-of-life Care
Introduction: Honest prognostication and information for patients are important parts of end-of-life care. This study examined whether an educational intervention could increase the proportion of patients who received information…
- Trial name
- NCT02091622
- Testing
- Educative intervention
- Where
- Sweden
- Volunteers
- 1,431 people
- Sponsor
- Umeå University
Palliative Care
Improving Palliative Care Through Teamwork
One in three Americans dies in a nursing home (NH) or in a hospital, shortly following transfer from a long-term care facility. The proportion of deaths occurring in NHs is projected to increase to 40% by 2020.
- Trial name
- IMPACTT (NCT01990742)
- Testing
- Palliative Care Team (PCTeam)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Rochester
Quality of Life, Stress
Music Therapy Intervention to Reduce Caregiver Distress at the End of Life
This is a study to assess the feasibility and acceptability of implementing a music therapy intervention for caregivers of hospitalized patients who are referred to inpatient hospice.
- Conditions
- Quality of Life, Stress, Anxiety, Depression
- Trial name
- NCT03322228
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Dyspnea
Feasibility Testing of a Hospice Family Caregiver Intervention to Improve Patient Dyspnea Care
This study is a pilot test of an intervention to train family caregivers of home hospice patients about recognizing and treating shortness of breath.
- Trial name
- NCT02441868
- Testing
- Shortness of breath recognition and treatment
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Wayne State University
Critical Care, Palliative Care
An Algorithmic Approach to Ventilator Withdrawal at the End of Life
The proposed study is an important, under-investigated area of ICU care for terminally ill patients undergoing terminal ventilator withdrawal.
- Trial name
- NCT03121391
- Testing
- Ventilator withdrawal algorithm
- Where
- 5 sites in United States
- Volunteers
- 165 people
- Sponsor
- Wayne State University
Palliative Care
Decision Making With Bioethical Perspective in Palliative Care en Mexico
All clinical practice includes decision making, and sometimes you are ethically challenging because of the consequences it will bring to the patient, the health professional or society in general.
- Trial name
- NCT03913390
- Where
- Mexico
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Heart Failure NYHA Class III, Heart Failure NYHA Class IV
Family Palliative and End-of-Life Care for Advanced Heart Failure
Overall objective is to test whether the 5-weekly family home palliative and end-of-life care (FamPALcare) intervention educational and supportive sessions will improve rural home end-of-life and palliative care (EOLPC) for…
- Trial name
- NCT04153890
- Testing
- FamPALcare
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- West Virginia University
Sickle Cell Disease and Pregnancy
Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana
The goal of this observational study is to determine the feasibility and effectiveness of initiating a multidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital.
- Trial name
- SCOB III (NCT07488091)
- Testing
- Multidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital.
- Where
- Ghana
- Volunteers
- 198 people
- Sponsor
- University of Ghana Medical School
HIV, Cancer
Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer
Background: There are very few documents to help young adults living with advanced cancer discuss their concerns and end-of-life preferences.
- Conditions
- HIV, Cancer, Chronic Granulomatous Disease, Dock 8 Deficiency
- Trial name
- NCT02108028
- Where
- 9 sites in United States
- Volunteers
- 272 people
- Sponsor
- National Cancer Institute (NCI)
Depressive Symptoms, Depression, Anxiety
Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness
Psychological and existential distress are a common cause of suffering among patients nearing the end of life, and a major reason for requesting medical aid in dying.
- Conditions
- Depressive Symptoms, Depression, Anxiety, Psychological Distress, Terminal Illness
- Trial name
- NCT04257227
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Ottawa Hospital Research Institute
Mental Illness, Stress
HEAlth Dialogues for Patients With Mental Illness in Primary Care
In the current project, primary health care patients with mental illness such as anxiety, depression, fatigue or sleep disorders will be followed.
- Conditions
- Mental Illness, Stress, Fatigue, Sleep Disorder
- Trial name
- HEAD-MIP (NCT05181254)
- Testing
- health dialogue
- Where
- Sweden
- Volunteers
- 167 people
- Sponsor
- Region Skane
Health Care Utilization, End Stage Disease
ACP Video Intervention for Patients With Life-Limiting Illness
The goal of this research is to increase patients' knowledge about advance care planning (ACP) discussions and hospice care for patients with serious illness receiving home-based care.
- Trial name
- NCT04778761
- Testing
- Home ACP Video
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Massachusetts General Hospital
End Stage Renal Disease, Decision Aid
A Guide to Conservative Care
This is a randomized pilot study to test the feasibility and acceptability of a patient decision aid on conservative care among older patients with advanced CKD and their close persons.
- Conditions
- End Stage Renal Disease, Decision Aid, Patient Engagement, Dialysis
- Trial name
- NCT04919941
- Testing
- A Guide to Conservative Care
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Washington
Palliative Patients, Surrogate Decision Maker
Multiprofessional Advance Care Planning and Shared Decision Making for End of Life Care
Multiprofessional Advance Care Planning and shared decision making for end of live care for terminal patients and their relatives.
- Trial name
- MAPS (NCT01914848)
- Testing
- Advance Care Planning ACP, Control Group
- Where
- Switzerland
- Volunteers
- 115 people
- Sponsor
- University of Zurich