Clinical trials: End of Life Decision Making
Clinical Decision-Making
Mixed Methods Study Web-based Life Support Decision Aid
Patients and families want to be involved in healthcare decisions. When the decision-making process does not engage older patients and their families, the care provided does not match patient preferences or meet their needs.
- Trial name
- eLSDA (NCT03271658)
- Testing
- Web based life support patient decision aid, Decision coaching
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Intervention Compliance, Usability
CSDM: A Trial to Improve Communication and Shared Decision Making Using a Web-Based Tool
The goal is to develop a pragmatic, scalable intervention to overcome problems with surrogate decision making in ICUs. The aim is to conduct a pilot study among surrogates and clinicians of 50 incapacitated patients at high risk…
- Conditions
- Intervention Compliance, Usability, Acceptability
- Trial name
- CSDM Pilot (NCT02955563)
- Testing
- CSDM Web-Based Tool Intervention
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Anxiety, Depression
Improving Patient and Family Centered Care in Advanced Critical Illness
One in five deaths in the U.S. occurs in or shortly after discharge from an intensive care unit (ICU), typically following decisions made by surrogate decision makers to forego life prolonging treatment.
- Trial name
- PARTNER (NCT01844492)
- Testing
- The PARTNER Intervention, ICU Usual Care Control
- Where
- United States
- Volunteers
- 1,420 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Communication, Advance Directives
Choice of Diction's Effect
The purpose of the research is to determine how the language used when discussing preferences about cardiopulmonary resuscitation (CPR) affects decisions regarding this (code status)
- Conditions
- Communication, Advance Directives, Decision Making, Cardiopulmonary Resuscitation
- Trial name
- CODE (NCT04896411)
- Testing
- Alternative phrasing for no code, Standard of care for no code
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Advance Care Planning
Advance Care Planning With Formerly Homeless Older Adults Residing in Permanent Supportive Housing
The homeless population is aging, with an increasing proportion of individuals over age 50 who experience accelerated aging, high rates of mortality, and a high risk of not having their wishes honored at the end of life.
- Trial name
- ACP-PSH (NCT06239896)
- Testing
- Facilitated Group ACP Session, Facilitated one-on-one ACP visits
- Where
- 6 sites in United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
End of Life Decision Making, Advance Care Planning
An Intervention to Improve End of Life Decision Making Among Homeless Persons
This project is a prospective, randomized controlled trial to improve the end of life experience for homeless persons by facilitating the expression of their wishes and enhancement of their dignity when facing serious illness…
- Trial name
- NCT00471016
- Testing
- Guided intervention
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Alzheimer Disease, Mild Cognitive Impairment
LEADing Dementia End-of-Life Planning Conversations
Advance care planning is important for all adults, but perhaps even more so for the 5.7 million persons with Alzheimer's disease or related dementia (ADRD), due to the progressive and protracted cognitive deterioration associated…
- Trial name
- LEAD (NCT05909189)
- Testing
- LEADing Dementia End-of-Life Planning Conversations
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Parkinson Disease
Preparing Patient-Caregiver Dyads with Parkinson's Disease for Future Decision Making
Persons with Parkinson's disease and family care partners are often unprepared to make difficult, future medical decisions. Earlier conversations about future medical decisions between persons with Parkinson's disease and family…
- Trial name
- NCT05084209
- Testing
- Parkinson's medical decision making support
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Purdue University
Palliative Care
Evaluation of an Intervention Designed to Enhance the Quality of Decision Support Provided to Patients Making Decisions About End-of-life Place of Care
Most dying cancer patients would prefer a home death yet die in an institution. Patients can experience uncertainty when weighing practical considerations, concern for others, and their personal ratings about the desirability and…
- Trial name
- NCT00614003
- Testing
- Decision support skills building Intervention
- Where
- 5 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
End Stage Renal Disease
A Representational Intervention to Promote Preparation for End-of-life Decision Making
The proposed randomized controlled trial will test the SPIRIT (Sharing the Patient's Illness Representations to Increase Trust) intervention designed to improve discussions about end-of-life care between patients and their…
- Trial name
- SPIRIT (NCT01259011)
- Testing
- the SPIRIT intervention
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Critical Illness
Multi-component Family Support Tool Intervention (FST)
The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die in intensive care units (ICUs) annually or survive…
- Trial name
- FST (NCT05019261)
- Testing
- Multi-component Family Support Intervention
- Where
- 7 sites in United States
- Volunteers
- 1,039 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Colonic Neoplasms, Breast Neoplasms
End-of-Life Care for African Americans
Racial differences in health care are documented across the health care continuum and persist in aging and end-of-life (EOL) care.
- Conditions
- Colonic Neoplasms, Breast Neoplasms, Lung Neoplasms
- Trial name
- NCT02320123
- Testing
- Educational DVD
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Brain Death, Renal Failure
Understanding Family Refusal
The investigators plan a secondary data analysis of an existing dataset to examine how individual decision-making differs from family decision-making in organ donation.
- Trial name
- NCT04303624
- Testing
- Health sciences survey
- Volunteers
- 1,007 people, healthy volunteers welcome
- Sponsor
- Yale-NUS College
Terminal Illness
ADJUST: A Study on MDT Prognostication
This study investigates how clinicians form intuitive judgements about the prognoses of palliative care patients after receiving advice perceived as coming from either a team member or an algorithm.
- Trial name
- ADJUST (NCT04568629)
- Testing
- Advice from the PiPS-B14 prognostic tool, Advice from another clinician
- Where
- United Kingdom
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- University College, London
Maternal Death, Neonatal Death
Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana
Introduction Maternal and neonatal mortality continue to be to be prominent public health issues in sub Saharan Africa including Ghana, with slow progress made towards attainment of Millennium Development Goals (MDG) 4 \& 5.
- Conditions
- Maternal Death, Neonatal Death, Postpartum Haemorrhage, Pre-eclampsia
- Trial name
- Accelerate (NCT02468310)
- Testing
- Maternal and neonatal emergency protocols
- Where
- Ghana
- Volunteers
- 65,831 people, healthy volunteers welcome
- Sponsor
- Hannah Brown Amoakoh
Chronic Kidney Diseases
A Pilot Study of The CKM JumpStart Tool
This is a randomized pilot study to test the feasibility and acceptability of a tool to promote discussion about conservative kidney management (CKM) among older patients with advanced CKD and their providers.
- Trial name
- NCT05753020
- Testing
- CKM Jumpstart Tool
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Washington
Palliative Care, Decision Making
Feasibility Of An Advanced Care Decision Aid Among Patients And Physicians_Matlock
The investigators propose an evaluation of an end of life patient decision aid (EOL-PtDA) developed by the Foundation for Informed Medical Decision Making using the RE-AIM (Reach Effectiveness, Adoption, Implementation, and…
- Conditions
- Palliative Care, Decision Making, Decision Support Techniques, Decision Support Systems, Clinical
- Trial name
- NCT01190488
- Testing
- End-of-Life / Advanced Care Decision Aid, Active Comparator
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver