Clinical trials: End-of-life Decision Making
Sudden Cardiac Arrest
Educational Videos to Improve Patient Decision Making and Race Disparities in Implantable Cardioverter Defibrillator Use
The investigators will examine whether an educational video increases patient knowledge about heart failure and the risk of sudden cardiac arrest and leads to greater satisfaction with information provided as compared to usual…
- Trial name
- VIVID-01 (NCT00918125)
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Duke University
Terminal Diseases
Decision Making in End of Life as Individual Preferences
It is not universal that terminally ill patients choose surrogate in the event of disagreement between the treating physician and the surrogate at the end of their lives.
- Trial name
- NCT02428504
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Parental Presence, Pediatric Ethics Consultation
Impact of Parental Presence at the Ethics Meeting in Neonatal Intensive Care
In neonatal intensive care, physicians are sometimes confronted with decisions to withhold or withdraw life-sustaining treatment for a critically ill newborn.
- Trial name
- PaReNCo (NCT07681518)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hôpital NOVO
Ischemic Stroke, Ischaemic Stroke With Coma
Decision Aid Feasibility Trial for Families of Critically Ill Stroke Patients
Severe strokes, including large artery acute ischemic stroke and intracerebral hemorrhage, continue to be the leading cause of death and disability in adults in the U.S.
- Conditions
- Ischemic Stroke, Ischaemic Stroke With Coma, Intracerebral Hemorrhage, Hemorrhagic Stroke
- Trial name
- NCT04143113
- Testing
- Decision Aid
- Where
- 2 sites in United States
- Sponsor
- University of Massachusetts, Worcester
Clinical Decision-Making
Mixed Methods Study Web-based Life Support Decision Aid
Patients and families want to be involved in healthcare decisions. When the decision-making process does not engage older patients and their families, the care provided does not match patient preferences or meet their needs.
- Trial name
- eLSDA (NCT03271658)
- Testing
- Web based life support patient decision aid, Decision coaching
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Organ Donation
Understanding Decision Making in the Intensive Care Unit: a National Study
Given how central Substitute Decision Makers (SDMs) are to the process leading to end of life decisions and sometimes, organ donation, it is striking how poorly understood this decision-making process is.
- Trial name
- NCT03850847
- Testing
- Step 1: Semi-structured Interviews, Step 2: National Telephone Survey
- Where
- 9 sites in Canada
- Volunteers
- 292 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Dementia
Preparation for End-of-Life Decision Making in Mild Dementia
The proposed study will adapt and pilot test an efficacious advance care planning interventions, Sharing Patient's Illness Representations to Increase Trust (SPIRIT), with patients with mild dementia and their surrogates to…
- Trial name
- NCT03311711
- Testing
- SPIRIT-in person, SPIRIT-remote, Usual care
- Where
- 5 sites in United States
- Volunteers
- 242 people
- Sponsor
- Emory University
Dementia Caregivers, End of Life Decision Making
A Culturally Adapted Decision Aid Intervention to Support Chinese American Dementia Caregivers in Feeding-Related Decisions
Family caregivers of people with dementia have to decide between tube feeding and hand feeding when persistent eating problems arise.
- Conditions
- Dementia Caregivers, End of Life Decision Making, Advanced Dementia
- Trial name
- NCT07370311
- Testing
- Chinese version of Making Choices Feeding Options for Patients with Dementia Decision Aid
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yaolin Pei
Decision Making, Terminal Illness
Organ Donation and End-of-life Decisions
Variation in organ donation after brain death (DBD) per million population varies markedly between countries, within country regions, between and within intensive care units (ICU).
- Conditions
- Decision Making, Terminal Illness, Tissue and Organ Procurement
- Trial name
- NCT04131140
- Where
- Sweden
- Volunteers
- 12,072 people
- Sponsor
- Swedish Intensive Care Registry
Discrimination, Racial, Communication
PRISM Race and Communication Pilot RCT
This is a pilot randomized trial of 60 patients to test feasibility, acceptability and efficacy of PRISM to improve resilience and facilitate improved patient-clinician communication in racially minorities patients with serious…
- Conditions
- Discrimination, Racial, Communication, Chronic Illness, Bias, Racial
- Trial name
- NCT04915079
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Washington
Palliative Care
ACP-Family Programme for Palliative Care Patients and Their Family Member
The goal of this clinical trial is to test the effectiveness of a structured, family-supported, patient-centred advance care planning (ACP) in palliative care patients and their family members.
- Trial name
- NCT05935540
- Testing
- ACP-Family
- Where
- 3 sites in Hong Kong
- Volunteers
- 170 people
- Sponsor
- The Hong Kong Polytechnic University
PATİENT CARE, Intensive Care Unit
Surgical ICU Nurses' Attitudes on End-of-Life Care
This study aims to explore the attitudes and behaviors of nurses working in surgical intensive care units (ICUs) towards end-of-life care, alongside identifying the barriers they face in providing such care.
- Trial name
- NCT06285305
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Kilis 7 Aralik University
Suicide, Assisted, Fasting
Self-directed Dying in the Netherlands
In 2007, the frequency of so-called 'self-directed dying' in the Netherlands was investigated, that is, the voluntary cessation of eating and drinking or the taking of lethal self-collected medication.
- Conditions
- Suicide, Assisted, Fasting, Decision Making
- Trial name
- NCT06186791
- Where
- Netherlands
- Volunteers
- 37,500 people
- Sponsor
- Erasmus Medical Center
End of Life Care, Muslim
Code Status Discussions in Muslim ICU Patients: Insights Into Physician-Family Communication
This observational study aims to explore the real-time experiences, perceptions, and challenges faced by intensive care unit (ICU) physicians during goals-of-care discussions-specifically Do Not Attempt Resuscitation (DNAR) and…
- Conditions
- End of Life Care, Muslim, Decision Making ,Shared
- Trial name
- FAITH-ICU (NCT07243041)
- Where
- Saudi Arabia
- Volunteers
- 320 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Colonic Neoplasms, Breast Neoplasms
End-of-Life Care for African Americans
Racial differences in health care are documented across the health care continuum and persist in aging and end-of-life (EOL) care.
- Conditions
- Colonic Neoplasms, Breast Neoplasms, Lung Neoplasms
- Trial name
- NCT02320123
- Testing
- Educational DVD
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Critical Illness, Ethics
Life Sustaining Treatments in Critically Ill Children
Summary of the Research on Withdrawing and Withholding Life-Sustaining Treatment for Critically Ill Children Background Medical treatments require regular evaluation to ensure they align with the patient's best interests…
- Conditions
- Critical Illness, Ethics, End of Life Care
- Trial name
- LST-Ped-Int (NCT07401420)
- Testing
- There is no intervention
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
End-of-life Decision-making
End-of-life Decision-making Among Young Patients With Advanced Cancer: a Grounded Theory Approach
The purpose of this qualitative research is to use grounded theory to explore and describe the thoughts of young advanced cancer patients regarding end-of-life care and how these thoughts influence the related decision-making…
- Trial name
- NCT06551831
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Alzheimer Disease, Mild Cognitive Impairment
LEADing Dementia End-of-Life Planning Conversations
Advance care planning is important for all adults, but perhaps even more so for the 5.7 million persons with Alzheimer's disease or related dementia (ADRD), due to the progressive and protracted cognitive deterioration associated…
- Trial name
- LEAD (NCT05909189)
- Testing
- LEADing Dementia End-of-Life Planning Conversations
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Critical Illness
Intensive Care Decision-making, Survival and Dying Well
The goal of this study is to investigate how the experiences of intensive care patients and their end-of-life wishes affect their willingness to accept intensive care treatment at different chances of survival.
- Trial name
- NCT06027684
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Manchester