Clinical trials: Endarterectomy, Carotid
Carotid Stenosis, Carotid Artery Diseases
Modified Method of Eversion Carotid Endarterectomy in Patients With Extensive Atherosclerotic Disease of Carotid Bifurcation
A prospective comparative randomized single-centre non-inferiority trial. The purpose of this study is to compares of modified method of eversion carotid endarterectomy with standard eversion carotid endarterectomy for 3,6 and 12…
- Trial name
- NCT04255316
- Testing
- Modified method of eversion carotid endarterectomy, Standard method of eversion carotid endarterectomy
- Where
- Russia
- Volunteers
- 126 people
- Sponsor
- Pirogov Russian National Research Medical University
Carotid Endarterectomy Surgery
Non-invasive Blood Pressure Monitoring in Carotid Surgery
Carotid endarterectomy surgery carries significant neurological and cardiac risks, requiring continuous monitoring of blood pressure.
- Trial name
- SPARK (NCT06965257)
- Testing
- Continuous non-invasive blood pressure monitoring
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Carotid Endarterectomy, Coronary Artery Bypass Grafting
Multidisciplinary CAE and CABG Surgery to Optimize the Management of High-risk Patients During the Perioperative Period
This project uses concurrent CEA+CABG combined surgery on high-risk patients with severe carotid artery stenosis and severe coronary artery stenosis.
- Trial name
- NCT04960488
- Testing
- carotid endarterectomy and coronary artery bypass grafting
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Regional Anesthesia, Carotid Endarterectomy
Hemi-diaphragmatic Paresis After Erector Spinae Plane Block
To assess the incidence of hemi-diaphragmatic paresis following ultrasound-guided erector spinae plane (ESP) block
- Trial name
- NCT04706780
- Testing
- ESP block
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people
- Sponsor
- Antalya Training and Research Hospital
Hypoxia-Ischemia, Brain, Ischemia, Vertebral Artery
Oxygen Concentration and Recovery After Carotid Endarterectomy
This study evaluates effects of high inspiratory oxygen on cerebral tissue oxygenation and patient recovery after carotid endarterectomy.
- Conditions
- Hypoxia-Ischemia, Brain, Ischemia, Vertebral Artery, Artery Stenosis, Carotid
- Trial name
- NCT02991976
- Testing
- Oxygen concentration
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- Osijek University Hospital
Cerebral Oxygen Saturation, Postoperative Delirium
Association Between Local Cerebral Oxygenation Monitoring and Postoperative Delirium in Carotid Endarterectomy
Postoperative delirium (POD) is a common perioperative complication, which can lead to adverse outcomes. Patients undergoing carotid endarterectomy (CEA) were elderly, complicated with vascular risk factors, cognitive…
- Conditions
- Cerebral Oxygen Saturation, Postoperative Delirium, Carotid Endarterectomy
- Trial name
- NCT05198635
- Testing
- local cerebral oxygen saturation
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing Tiantan Hospital
Carotid Stenosis, Ischemia Reperfusion Injury
Perioperative Time Course of MMP-9 and Its Inhibitor During Carotid Artery Stenting and Carotid Endarterectomy
The aim was the comparison of the perioperative time courses of matrix metalloproteinase-9 (MMP-9) and its inhibitor (TIMP-1) during elective carotid artery stenting (CAS).
- Trial name
- NCT03410576
- Testing
- Carotid artery stenting, Carotid endarterectomy
- Where
- Hungary
- Volunteers
- 25 people
- Sponsor
- University of Pecs
Carotid Endarterectomy
Vascular Post Market Review
The primary objective of this study is to confirm that properties of CardioCel provide operative benefit to surgeons when compared to Dacron, CorMatrix, and all other bovine pericardium not treated with proprietary ADAPT…
- Trial name
- NCT02681341
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor Research Institute
Carotid Atherosclerosis, Regional Anaesthesia Morbidity
Ultrasound-guided Intermediate Cervical Block Versus Superficial Cervical Block for Carotid Endarterectomy (CERVECHO)
The aim of this prospective, randomised, controlled study is to compare the efficacy of ultrasound-guided intermediate cervical block to superficial block for carotid endarterectomy.
- Trial name
- CERVECHO (NCT01742845)
- Testing
- Ultrasound-guided administration of ropivacaine 4.75 mg/ml, landmark based superfical ropivacaine 4.75 mg/ml injection
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Stroke
Risk Prediction of Carotid Endarterectomy by Vascular Ultrasound Evaluation
Carotid endarterectomy (CEA) is one of the surgical treatment methods for the reconstruction of arterial stenosis or occlusion. Perioperative stroke, cerebral hemorrhage,hyperperfusion syndrome and death are main complications of…
- Trial name
- NCT03785626
- Testing
- CEA surgery
- Where
- China
- Volunteers
- 1,498 people
- Sponsor
- Xuanwu Hospital, Beijing
Carotid Artery Disease
Protected Carotid Artery Stenting in Subjects at High Risk for Carotid Endarterectomy (CEA) (PROTECT)
The purpose of this study is to evaluate the long-term safety and efficacy of the Xact™ Rapid Exchange Carotid Stent System used in conjunction with the Emboshield® Pro Rapid Exchange Embolic Protection System (Generation 5) and…
- Trial name
- PROTECT (NCT00402740)
- Testing
- Xact Stent with either Emboshield Pro (Gen 5) or Emboshield (Gen 3)
- Where
- 38 sites in United States
- Volunteers
- 322 people
- Sponsor
- Abbott Medical Devices
Atherosclerosis of Artery, Carotid Endarterectomy
Associations of Carotid Plaque Characteristics With Brain Perfusion and Cognitive Function in Patients Undergoing CEA
Stroke is one of the leading causes of death and disability-adjusted life-years worldwide. Carotid high-risk atherosclerotic plaques are considered to be one of the major sources of ischemic stroke.
- Trial name
- NCT04955015
- Testing
- carotid endarterectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Transient Ischemic Attack, Carotid Stenosis
EVA3S: Endarterectomy Versus Angioplasty in Patients With Severe Symptomatic Carotid Stenosis
The purpose of this study is to evaluate whether carotid angioplasty with stent (CAS) is as safe and effective as carotid surgery in regards to: 1. the risk of stroke and death within 30 days of the procedure; 2.
- Conditions
- Transient Ischemic Attack, Carotid Stenosis, Atherosclerosis
- Trial name
- NCT00190398
- Testing
- Carotid angioplasty and stenting with cerebral protection
- Where
- France
- Volunteers
- 900 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated…
- Conditions
- Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
- Trial name
- IMPROVE (NCT07556887)
- Testing
- IMPROVE Risk Model
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Maastricht University Medical Center
In-Stent Carotid Artery Restenosis
Carotid Endarterectomy vs. Repeated Carotid Angioplasty and Stenting for In-Stent Restenosis
Patients with in-stent restenosis in carotid artery indicated to carotid intervention will be randomized into repeated carotid percutaneous transluminal angioplasty with or without stenting or carotid endarterectomy with stent…
- Trial name
- CERCAS (NCT05390983)
- Testing
- Carotid endarterectomy with stent removal
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- University Hospital Ostrava
Carotid Artery Stenosis, Ischemic Stroke
Platelet Reactivity and MES During CEA
The purpose of this study is to analyze the association between aspirin efficacy and general platelet reactivity in relation to microembolic signals (MES) during carotid endarterectomy (CEA).
- Conditions
- Carotid Artery Stenosis, Ischemic Stroke, Myocardial Infarction, Aspirin Resistance
- Trial name
- NCT01547039
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- UMC Utrecht
Stroke, Stenosis
Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis
The purpose of the present prospective, randomized, double-blind, double dummy controlled multicenter pilot study is to investigate whether abciximab, compared with aspirin, is able to reduce the rate of recurrent ischemic…
- Trial name
- NCT00126139
- Testing
- Abciximab
- Where
- 5 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Regional Anesthesia Morbidity, Carotid Artery Diseases
Effect of Regional Versus General Anesthesia on Thirty-day Outcomes Following Carotid Endarterectomy: a Matched-pairs Cohort Study.
The goal of this observational study is to assess the effect of regional versus general anesthesia on carotid endarterectomy thirty-day outcomes.
- Conditions
- Regional Anesthesia Morbidity, Carotid Artery Diseases, Perioperative/Postoperative Complications
- Trial name
- NCT05706688
- Testing
- Anesthetic technique (regional versus general)
- Volunteers
- 37,204 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Carotid Disease
Study of Regional Cerebral Oxygenation and Brain Blood Volume Changes During Carotid Endarterectomy Using the NeurOS System
Study of Regional cerebral Oxygenation and Brain Blood Volume changes during Carotid Endarterectomy using the NeurOS system
- Trial name
- COBBV-CE (NCT03981757)
- Testing
- NeurOS
- Where
- United States
- Sponsor
- University of Louisville
Choroid, Carotid Stenosis
Ocular Effects of Carotid Endarterectomy
All patients undergoing carotid endarterectomy in Shaare Zedek Medical Hospital, during about 1 year, will be offered to participate. Retinal and choroidal structural changes will be assessed using swept-source OCT technology
- Conditions
- Choroid, Carotid Stenosis, Carotid Endarterectomy
- Trial name
- NCT02448355
- Testing
- OCT swept source DRI-Atlantis, Topcon
- Volunteers
- 30 people
- Sponsor
- Shaare Zedek Medical Center