Clinical trials: Endocrine Disorder
Diabetes Mellitus, Type 2, Arrhythmia, Cardiac
Hypoglycaemia and Cardiac Arrhythmias in Type 2 Diabetes
Twenty-one patients with insulin-treated type 2 diabetes with diabetic complications will be recruited to Part 1 of the study, a three-hour combined hyper- and hypoglycaemic clamp, along with a control group of twenty-one…
- Trial name
- HYPO-HEART (NCT03150030)
- Testing
- Combined hyper- and hypoglycaemic clamp, Loop recorder (Reveal LINQ, Medtronic, Minneapolis, MN, USA), Continuous glucose monitoring (iPro2, Medtronic, Minneapolis, MN, USA)
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Hypertension in Pregnancy, Diabetes Mellitus in Pregnancy
Insulin Resistance and Hypertensive Disorders in Pregnancy
The purpose of this study is to determine whether insulin resistance might affect the pathogenesis of hypertensive disorders in pregnancy since midtrimester.
- Trial name
- NCT00412230
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Messina
Diabetes Mellitus, Type 2
Bioequivalence Study of Two Albiglutide Drug Products in Healthy Adult Subjects
Albiglutide (Alb) is a novel analogue of glucagon-like peptide-1 (GLP-1) has been developed and approved for the treatment of type 2 diabetes mellitus.
- Trial name
- NCT02660736
- Testing
- Albiglutide Liquid Auto-injector, Albiglutide Lyophilized DCC Pen Injector
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Type2 Diabetes, PreDiabetes
Secular Trends in the Prevalence of Diabetes in India
Series of epidemiological studies have been carried out by the research team since 1988 studying the changes in the prevalence of type 2 diabetes, prediabetes and associated risk factors.
- Trial name
- STRiDE-I (NCT03490136)
- Where
- India
- Volunteers
- 9,848 people, healthy volunteers welcome
- Sponsor
- India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals
Type 2 Diabetes
Bias Source of Signal in SCOUT DS
The primary objective is to identify device characteristics, components or subsystems that manifest as screening score bias in SCOUT DS.
- Trial name
- BSOS (NCT01550328)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Secondary Hyperparathyroidism, Hypocalcemia
Bioequivalency Study of Calcitriol Tablets Under Fasting Conditions
The objective of this study was to assess the bioequivalence of Roxane Laboratories' Calcitriol capsules, 0.25 mcg, to ROCALTROL® capsules, 0.25 mcg (Roche) using a single-dose, 2-treatment, 2-period, crossover design, under…
- Trial name
- NCT00601328
- Testing
- Calcitriol
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Gestational Diabetes Mellitus
The Role of Pregnancy-induced Gallbladder Dysmotility in the Pathophysiology of Gestational Diabetes Mellitus
The primary aim of the study is to evaluate postprandial gallbladder emptying and plasma concentrations of the glucose-lowering and satiety-promoting gut hormone glucagon-like peptide 1 (GLP-1) during third trimester of pregnancy…
- Trial name
- NCT04108065
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
HIV Infections
Motiv82Change: an HIV Prevention Study for Young Latino Men
The purpose of this study is to develop and pilot test a culturally and developmentally tailored Motivational Enhancement Intervention (MEI) to reduce risky sex (unprotected anal sex and multiple partners) among young Hispanic…
- Trial name
- Motiv82Change (NCT00877695)
- Testing
- Entre Culturas: Navigating Culture, Identity, and HIV Risk
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Breast Cancer, Colo-rectal Cancer
The French E3N Prospective Cohort Study
The French E3N cohort was initiated in 1990 to investigate the risk factors associated with cancer and other major non-communicable diseases in women.
- Conditions
- Breast Cancer, Colo-rectal Cancer, Parkinson Disease, Asthma
- Trial name
- E3N (NCT03285230)
- Where
- France
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Diabete Type 2, Obesity
Effects of Plant Based Lipids on Glucose Regulation and Cognitive Variables
The overall goal is to increase the knowledge that can be used for the development of food products with anti-diabetic properties, with the purpose to facilitate healthier food choices for people.
- Trial name
- NCT05276128
- Testing
- lipids
- Where
- 2 sites in Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Lund University
Type 2 Diabetes
Vitamin D, Glucose Control and Insulin Sensitivity in African-Americans
North American blacks tend to have low blood levels of vitamin D because pigmentation blocks vitamin D production in the skin. They also have higher rates of developing type 2 diabetes and higher rates of complications from the…
- Trial name
- NCT00784511
- Testing
- cholecalciferol, microcrystalline cellulose
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tufts University
Type 2 Diabetes Mellitus, Binge-Eating Disorder
Preventing Type 2 Diabetes in Black Emergent Adult
Black Americans are disproportionately affected by diabetes, with nearly double the rates of type 2 diabetes mellitus (T2DM), compared to non-Hispanic White adults.
- Conditions
- Type 2 Diabetes Mellitus, Binge-Eating Disorder, Binge Eating, Obesity
- Trial name
- NCT06848244
- Testing
- Appetite Awareness Training (AAT), Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Proteinuria, Diabetic Nephropathy
FGF-23 and Endothelial Dysfunction in Diabetic Proteinuric Patients
There is no data about the effects of Renin angiotensin system blockage (RAS) on FGF23 and ADMA levels in diabetic patients with proteinuria.
- Conditions
- Proteinuria, Diabetic Nephropathy, Chronic Kidney Disease
- Trial name
- NCT01703234
- Testing
- Ramipril
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Gestational Diabetes Mellitus
Lifestyle Intervention and Prevention of Gestational Diabetes Mellitus
The number of women with gestational diabetes mellitus (GDM) had been increasing. Maternal GDM has a great impact on both the health of the mothers and the offspring.
- Trial name
- NCT02368600
- Testing
- Lifestyle modification program
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Turner's Syndrome
Turner Syndrome: Genotype and Phenotype
This study examines the clinical and genetic factors related to Turner syndrome, a disorder of the sex chromosomes. Humans usually have 23 pairs of chromosomes-thin strands of DNA-in the nucleus of every cell, which contain genes…
- Trial name
- NCT00006334
- Where
- United States
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Polycystic Ovary Syndrome, c Type Natriuretic Peptide
Comparison of Serum C Type Natriuretic Peptide Levels Between Polycystic Ovary Syndrome Patients and Healthy Women
Recent studies have shown that C natriuretic peptide is produced from granulosa cells, increasing cumulative guanosine monophosphate (cGMP) production by affecting cumulus cells through natriuretic peptide receptors.
- Conditions
- Polycystic Ovary Syndrome, c Type Natriuretic Peptide, Menstrual Irregularity, Hyperandrogenism
- Trial name
- CNP (NCT04006171)
- Testing
- C type natriuretic peptide
- Where
- Cyprus
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Diabetes Mellitus
Feasibility of ECG-Based Glucose Monitoring System
This is a single-center, open-label clinical trial to assess the feasibility of using ECG information in estimating glucose level continuously in adult subjects.
- Trial name
- NCT06883682
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Singular Wings Medical Co., Ltd.
Type 1 Diabetes
Mechanisms of Hypoglycemia Associated Autonomic Dysfunction, Q4-Atomoxetine
This study is aimed at determining if the drug Atomoxetine (Strattera-used to treat Attention Deficit Hyperactivity Disorder(ADHD) has effects on the body's ability to defend itself against low blood sugar.
- Trial name
- NCT00780650
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Diabetes Mellitus
The Relationship Between Voiding Dysfunction and Intravesical Sensory Threshold in Diabetes Women
The investigators will recruit a cross-sectional group of diabetic women in internist clinics. UDS will be applied for voiding function in each case.
- Trial name
- NCT00155610
- Testing
- intravesical current perception test
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus
Comparative Measurement of Microcirculation and Other Parameters With the Vital USA VitalDetect™ in Patients With Diabetes Mellitus Type 1 and Type 2 Versus Healthy Participants
The purpose of this clinical study is to optimize the measurement algorithm of the Vital USA VitalDetectTM in measuring the microcirculating blood flow.
- Trial name
- NCT06063759
- Testing
- VitalDetect
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sciema UG
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