Clinical trials: Endocrine Disorder
Gestational Diabetes Mellitus, Exercise
Moderate-to-vigorous Physical Activity for Glycemic Control in Patients With Gestational Diabetes Mellitus
Patients with newly diagnosed gestational diabetes will be recruited. The control group with get routine diet and exercise counseling.
- Trial name
- NCT01748305
- Testing
- Moderate-to-vigorous intensity exercise
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Diabetes Mellitus, Chronic Disease
Meta-analyses of Liquid Versus Solid Calories and Body Weight
Consumption of sugar-sweetened beverages (SSBs) has been linked to rising rates of overweight and obesity. The most prominent mechanism to explain the link between SSBs and obesity is that liquid calories are not perceived by the…
- Conditions
- Diabetes Mellitus, Chronic Disease, Cardiovascular Diseases, Prediabetic State
- Trial name
- NCT02702440
- Testing
- Liquid calories from sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Polycystic Ovary
Serum Ghrelin in Polycystic Ovary Syndrome
measuring serum gherlin in polycystic ovary syndrome patients and compare it to healthy levels
- Trial name
- NCT02087410
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- amr hesham el etreby
Cardiovascular Diseases, Diabete Type 2
EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Patients
Nordic Walking (NW) is a biomechanically correct walking technique that originated in Finland in the 1930s as an off-season training method for cross-country skiers.
- Conditions
- Cardiovascular Diseases, Diabete Type 2, Overweight and Obesity
- Trial name
- VENERE (NCT05987410)
- Testing
- Nordic Walking (NW), Standard Rehabilitation (SR), Cardiological Counselling (CC)
- Where
- Italy
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Cardiovascular Diseases, Type 2 Diabetes
Primary Prevention With the Lifestyle Tool
In this study participants will be randomized to use a digital lifestyle tool over three years or to a control group without access to the tool.
- Trial name
- NCT05309850
- Testing
- Lifestyle tool
- Where
- Sweden
- Volunteers
- 90,000 people, healthy volunteers welcome
- Sponsor
- Region Skane
Obesity, Diabetes
Calcium-protein Co-ingestion and Gut Hormones
Gut hormones have therapeutic potential in the prevention and treatment obesity and type 2 diabetes (T2D). Rodent evidence suggests that calcium may potentiate the effects of protein ingestion on gut hormone secretion.
- Trial name
- NCT03370497
- Testing
- Milk Mineral Supplement, Whey Protein Hydrolysate
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Bath
Diabetes Mellitus, Type 2
A Study To Evaluate The Effects Of PF-05175157 In Healthy Volunteers
The primary purpose of this study is to evaluate pharmacodynamics of single oral doses of PF-05175157 in a dose-dependent fashion in healthy volunteers
- Trial name
- NCT01537497
- Testing
- PF-05175157
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Pfizer
Diabetic Retinopathy
Proteomic Study of Plasma Exosomes in Patients With Diabetic Retinopathy
Objective: Explore the biomarkers related to proliferative diabetic retinopathy by analyzing the protein expression profile changes of plasma exosomes in patients with difference phases of diabetic retinopathy, and investigate…
- Trial name
- NCT06188013
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Diabetes
Comparison of Premixed Insulin With Basal-plus Insulin in Type 2 Diabetes Patients
Comparison of efficacy and safety of different insulin regimens between basal bolus and premixed insulin in poorly controlled type 2 diabetes
- Trial name
- COMPAR (NCT02219750)
- Testing
- switch twice-daily insulin
- Where
- Taiwan
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Ulcer Foot, Diabetes
Optical Imaging For Assessment of Foot Perfusion
This study is designed to evaluate the ability of Spatial Frequency Domain Imaging (SFDI) to measure perfusion in lower extremities and to understand how it might be used in a podiatry clinic.
- Trial name
- NCT03144050
- Testing
- SFDI Imaging
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Modulated Imaging Inc.
Type 2 Diabetes Mellitus
A Study to Compare the Pharmacokinetics and the Safety Between a Fixed-dose Combination Administration of "BR3005" and Co-administration of "BR3005-1" and "BR3005-2" Under Fasting Conditions in Healthy Adult Volunteers
The objective of this clinical study is to compare the pharmacokinetics and the safety between a fixed-dose combination administration of "BR3005" and co-administration of "BR3005-1" and "BR3005-2" under fasting conditions in…
- Trial name
- NCT06289920
- Testing
- BR3005, BR3005-1, BR3005-2
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Diabetes, Diabetes Mellitus, Type 2
A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NNC0148-0000-0362 in Healthy Subjects
This trial is conducted in Europe. The aim of this trial is to investigate the safety, tolerability, pharmacokinetics (exposure of drug) and pharmacodynamics (effect of drug) of NNC 0148-0000-0362 as tablets in healthy…
- Conditions
- Diabetes, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT01597713
- Testing
- NNC 0148-0000-0362, insulin glargine
- Where
- Germany
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Diabetes
Distinguishing Participant Groups Using Autonomic Dysfunction
A study population with impaired fasting glucose levels, impaired glucose tolerance levels and diabetes (with or without complications) along with healthy patients will be chosen as participants.
- Trial name
- NCT05199350
- Testing
- Device Name: ANSiscope
- Where
- India
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- DyAnsys, Inc.
Diabetes, Wound Infection
Tissue Penetration of Ceftolozane/Tazobactam in Diabetic Patients With Lower Limb Infections
This study will determine the tissue penetration of ceftolozane/tazobactam (Zerbaxa, Merck \& Co.), a novel β-lactam/β-lactamase combination antibiotic, into the extracellular, interstitial fluid of soft tissue in diabetic…
- Conditions
- Diabetes, Wound Infection, Healthy Volunteers
- Trial name
- NCT02620774
- Testing
- Ceftolozane/tazobactam, Microdialysis Catheter Insertion
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Type 1 Diabetes
Closed-loop Glucose Control for Automated Management of Type 1 Diabetes
We hypothesize that our integrated closed-loop glucose-control system can provide effective, tight, and safe blood glucose (BG) control in type 1 diabetes, thereby establishing the feasibility of closed-loop BG control.
- Trial name
- NCT00811317
- Testing
- Closed-loop
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Diabetes, Healthy
To Investigate the Blood Concentration of Liraglutide as Well as the Effects on Glucose and Insulin After 21 Days of Daily Subcutaneous Injections of Liraglutide or Placebo
This trial is conducted in Asia. The aim of this clinical trial is to investigate the blood concentration of liraglutide (pharmacokinetics) as well as the effects on glucose and insulin (pharmacodynamics) after 21 days of daily…
- Trial name
- NCT00761540
- Testing
- liraglutide
- Where
- China
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
PreDiabetes, Nutrition
Zinc, Chromium, Vitamin C, and Copper Combination Supplement for Prediabetes Progression
Currently, the incidence of diabetes mellitus is increasing worldwide. People with prediabetes have higher risk to develop diabetes mellitus type 2.
- Trial name
- CHANGE (NCT04511468)
- Testing
- Zinc, Chromium, Vitamin C, and Copper Supplementation, Standard healthy lifestyle intervention
- Where
- Indonesia
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Diabetes, Hearing Problems
Screening and Characterization of Hearing Disorders in Diabetic Persons
Diabetes is now the most common chronic disease, affecting nearly 6% of the population in Western populations. Diabetic neuropathy is a priori the most common and the most common specific complications of diabetes.
- Trial name
- DeCaTAuDiab (NCT03437135)
- Testing
- Glasgow Hearing Status Inventory questionnaire
- Where
- France
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Insulin Resistance, Diabetes
Diabetes, Insulin Resistance and Body Composition
The goal of this retrospective study is to learn about the correlation between diabetes, insulin resistance and body compositions.
- Trial name
- NCT06724068
- Testing
- Diabetes，Insulin resistance，Control
- Where
- China
- Volunteers
- 515 people, healthy volunteers welcome
- Sponsor
- Xuan Song
Diabetes Mellitus
Effects of Standardized Meals on the Metabolic, Hormonal and Inflammatory Responses in Human
Meal composition is important for blood sugar levels in patients with diabetes. The aim of this study is to investigate if a meal composition of fat, protein and carbohydrate is important for the hormonal and inflammatory…
- Trial name
- NCT02544568
- Testing
- Meals
- Where
- Sweden
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
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