Clinical trials: Endocrine Disruptors
Pregnancy, Endocrine System
Effect of an Environmental Health Education Program on Pregnant Women in Order to Reduce Endocrine Disruptor Exposition
Endocrine disruptors are known as a cancer cause. On pregnant women, it can induce major foetal pathology and impact growth. Among those molecules, bisphenol-A (BPA) is a plasticizer that can be found on cans and water.
- Conditions
- Pregnancy, Endocrine System, Prevention Program
- Trial name
- NCT03233984
- Testing
- sensibilisation program "Ma maison, mon environnement santé"
- Where
- France
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Endocrine Disruptors, Inflammation
The Plastic Exposure Reduction Transforms Health Trial
The goal of this randomized controlled trial is to learn if an intervention of reducing plastic exposure through diet, personal care and cleaning products can improve health outcomes in adult participants with cardiometabolic…
- Conditions
- Endocrine Disruptors, Inflammation, Cardiometabolic Risk Factors
- Trial name
- PERTH (NCT06571994)
- Testing
- Low Plastic Intervention
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Western Australia
Environmental Exposure
A Personalized Biomonitoring and Report-back Intervention to Reduce Exposure to Endocrine Disrupting Chemicals
The goal of this clinical trial is to learn if a personalized biomonitoring report-back and educational intervention in child-bearing aged men and women can reduce endocrine disrupting chemicals (EDCs) measured in urine, increase…
- Trial name
- REED (NCT06450951)
- Testing
- Urinary EDC metabolite testing, Educational curriculum
- Where
- United States
- Volunteers
- 1,074 people, healthy volunteers welcome
- Sponsor
- Million Marker Wellness, Inc.
Amenorrhea, Dysmenorrhea
Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants
This project is examining the reproductive effects of exposure to certain compounds that are suspected to act on the endocrine system, e.g. they may act like or interfere with hormones such as estrogen.
- Conditions
- Amenorrhea, Dysmenorrhea, Oligomenorrhea, Anovulation
- Trial name
- NCT00011388
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Environmental Exposure
Minority-focused Environmental Health Education and Tracking Pilot Study
The goal of this study is identify educational material related to EDC exposures that is culturally appropriate for the black community and test the usability of the material. The main questions this study aims to answer are: 1.
- Trial name
- MEET (NCT07461857)
- Testing
- Education curriculum
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Million Marker Wellness, Inc.
Asthma, Atopy
The JOIN Project: The Air in Diagnosis and Prevention of Asthma and Allergy
The JOIN project combines the health and indoor environment research areas to contribute in the development and validation of a new asthma diagnosis method through exhaled VOC analysis.
- Trial name
- JOIN (NCT02802891)
- Where
- Portugal
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Infertility, Overweight and Obesity
Healthy Parents - Healthy Children. Weight Loss Before Fertility Treatment
The detrimental effect of overweight and obesity on fecundity has been well documented. The investigators wish to investigate the intervention program for weight loss before fertility treatment.
- Conditions
- Infertility, Overweight and Obesity, Weight Loss, Vaginal Flora Imbalance
- Trial name
- NCT04721938
- Testing
- Systematic weight loss intervention
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Health Disparities, Education
Clean Beauty in Newark, NJ
Every day, consumers use personal care products containing thousands of manmade chemicals. Growing evidence suggests that personal care products specifically marketed to Black women (e.g., hair straighteners and oils, skin…
- Trial name
- NCT07216898
- Testing
- Chemical Exposure Prevention
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Pharmacokinetic Study
Toxicokinetic Study of Dichlorobisphenol A After an Oral or Dermal Single Dose in Healthy Volunteer.
The objective of this study is to determine toxicokinetic parameters of deuterated d12-Cl2BPA after the administration of a single low dose (50 µg/kg) to healthy volunteers via oral or dermal routes.
- Trial name
- PRECEPT (NCT04788810)
- Testing
- Administration of d12-Cl2BPA
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Polycystic Ovary Syndrome
Endocrine Disruptors, Toxic and Essential Chemical Elements and Polycystic Ovary Syndrome
Studies have shown that endocrine disruptors (EDs) and toxic and essential chemical elements affect women's reproductive health and may play a role in the development of polycystic ovary syndrome (PCOS).
- Trial name
- NCT06968455
- Testing
- parabens
- Where
- Slovenia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Unexplained Infertility, Polycystic Ovarian Syndrome
Endocrine Disrupting Chemicals: Potential Effects on Male and Female Reproductive Health in Saskatchewan
The overall objective of this study is to determine whether serum BPA and/or phthalate concentrations differ in fertile versus infertile men and women in Saskatchewan. The investigators will test the following hypothesis: 1.
- Conditions
- Unexplained Infertility, Polycystic Ovarian Syndrome, Male Infertility
- Trial name
- NCT02272439
- Where
- Canada
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Women Who Are Aged 18-49 Years, Able to Read, Write
Reducing Endocrine-Disrupting Chemical Exposure in Reproductive-Age Women: A Pender Model-Based RCT
Abstract Background: Endocrine-disrupting chemicals (EDCs) are widely encountered in daily life and may adversely affect reproductive health.
- Conditions
- Women Who Are Aged 18-49 Years, Able to Read, Write, Voluntarily Agree to Participate in the Study
- Trial name
- NCT07773233
- Testing
- Intervention Group
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Harran University
Obesity, Metabolic Syndrome
Benzoates - an Obesogenic Endocrine Disrupting Chemical
The benzoic acid derivatives sodium and potassium benzoate are preservatives that are commonly added to food and beverages to inhibit microbial growth and prevent spoilage.
- Trial name
- NCT03190785
- Testing
- Benzoic acid washout and exposure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Endocrine Disruptors in Newborns and Infants
Impact of Parental Training in Endocrine Disruptors on the Excretion of Urinary Biomarkers in Newborns
The impact of the environment on health, responsible for a quarter of all deaths worldwide and costing more than €160 billion a year, is difficult to assess because of the complexity of exposure and interactions.
- Trial name
- FLOCON (NCT07349927)
- Testing
- Training, Questionnaires, Urinary dosage
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Childhood Obesity, Life Style
LIMIT Early Adiposity Rebound in Children
Childhood obesity is a strong predictor of adult obesity with health and economic consequences for the individual and society. Adiposity rebound (AR) is a rise in the Body Mass Index occurring between 3-7 years.
- Conditions
- Childhood Obesity, Life Style, Intestinal Microbiome
- Trial name
- LIMIT (NCT04960670)
- Testing
- Evaluation of microbiome and maternal/infant lifestyle
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Endocrine Disrupting Chemicals, Environmental Exposure
Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals in Adults of Child-Bearing Age
The goal of this intervention study is to determine to what extent the Million Marker (MM) program reduces users' endocrine disruption chemical (EDC) exposure levels and changes their environmental health awareness and behaviors.
- Conditions
- Endocrine Disrupting Chemicals, Environmental Exposure, Health Literacy, Bisphenol A
- Trial name
- NCT05780047
- Testing
- Mail-in Urine Test for EDCs
- Where
- United States
- Volunteers
- 434 people, healthy volunteers welcome
- Sponsor
- Million Marker Wellness, Inc.
Endocrine Disrupting Chemicals, Health Literacy
The Effect of Nursing Education Intervention on Women's Health Literacy of Plasticizers
Environmental hormone (environmental hormone), also known as "endocrine disrupting chemicals" (EDCS), is a pollutant that affects the endocrine system and causes diseases and dysfunction throughout the life cycle.
- Trial name
- NCT05024227
- Testing
- Experimental: nursing education interventions (including e-health platform assistance)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Oxidative Stress, Endocrine Disrupting Chemicals
Oxidative Stress and Bisphenol A (BPA) Impact With Polycystic Ovary Syndrome (PCOS)
Both oxidative stress and Bisphenol A (BPA) had been associated with polycystic ovary syndrome (PCOS). BPA, one of endocrine-disrupting chemicals (EDCs), is an environmental estrogen used in the synthesis of plastics, is a…
- Conditions
- Oxidative Stress, Endocrine Disrupting Chemicals, Polycystic Ovary Syndrome
- Trial name
- NCT01600872
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ming-I Hsu
Precocious Puberty, Central, Executive Dysfunction
Hypiend - Multicomponent Behavioral Intervention in Pre-puberal Children (Hypiend-PPC)
This study is part of the European Hypiend project, which aims to explore the effects of co-exposure to endocrine-disrupting chemicals (EDCs) on the function and epigenetic programming of the hypothalamic-pituitary-adrenal (HPA)…
- Trial name
- Hypiend-PPC (NCT07411001)
- Testing
- Multi-Component Behavioral intervention, Information
- Where
- Belgium
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Sciensano
Breast Cancer
Everyday Exposures: How Chemicals and Weight Impact Breast Cancer Risk
To learn about breast cancer survivors' and their family members' knowledge of and interest in learning about environmental exposures related to personal care products.
- Trial name
- NCT07137468
- Testing
- Surveys, Video
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center