Clinical trials: Endocrine Female Infertility
Anovulation, Infertility
Gonadotrophin Dosage Using a Threshold Nomogram for Ovulation Induction in WHO Group II Anovulatory Infertility
Ovulation disorders are a common cause of infertility in women. Most of these women can be classified as World Health Organization (WHO) Group II anovulatory patients as they have irregular or absent menstrual cycles but normal…
- Trial name
- NCT01250821
- Testing
- Menopur
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Anovulation
Comparison of Anastrozole Verses Clomiphene Citrate in Stimulating Follicular Growth and Ovulation in Infertile Women With Ovulatory Dysfunction
The purpose of this study is to investigate and compare the safety and efficacy of various doses of the aromatase inhibitor (anastrozole) versus clomiphene citrate in stimulating follicular growth and ovulation in infertile women…
- Trial name
- NCT00213148
- Testing
- Anastrozole 1 mg, Anastrozole 5 mg, Anastrozole 10 mg
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- EMD Serono
Infertility, Female, Polycystic Ovary Syndrome
Antioxidant Supplement Associated With Oral Probiotics in Patients With PCOS in IVF
The aim of the study is to study the effect of an antioxidant food supplement associated with probiotics on the oocyte quality response, oxidative stress and microbiota function in an in vitro fertilization cycle in patients with…
- Trial name
- NCT04670393
- Testing
- FertyBiotic Woman Plus
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fertypharm
Infertility, Female, Unexplained Infertility
Serum Kisspeptin Levels in Infertile Women
The study population is comprise of 90 women those age varies between 18-38 year-old. The first group will comprise of 30 women with polycystic ovaries or anovulatory cycles, the second group will comprise of 30 women with…
- Conditions
- Infertility, Female, Unexplained Infertility, Anovulation
- Trial name
- NCT03018314
- Testing
- Blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Polycystic Ovary Syndrome, Infertility
Pulsatile Gonadotropin-releasing Hormone for Infertility in Non-obese Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) patients are often accompanied by infertility. Non-obese PCOS infertility is more difficult to treat than obese PCOS.
- Conditions
- Polycystic Ovary Syndrome, Infertility, Ovulation Disorder
- Trial name
- NCT03989024
- Testing
- Gonadorelin, Clomiphene
- Where
- China
- Volunteers
- 78 people
- Sponsor
- RenJi Hospital
Primary Ovarian Insufficiency, Low Ovarian Reserve
Rejuvenation of Premature Ovarian Failure With Stem Cells
The ROSE-1 study is designed to determine the efficacy of bone marrow derived stem cell therapy on ovarian function recovery in subjects with idiopathic and other types of premature or primary ovarian failure (POF or POI) and low…
- Conditions
- Primary Ovarian Insufficiency, Low Ovarian Reserve, Premature Ovarian Failure
- Trial name
- ROSE-1 (NCT02696889)
- Testing
- ROSE-1 Protocol
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Illinois Chicago
Healthy, PCOS
In Vitro Maturation of Human Eggs
CCRM Fertility, a global pioneer in fertility treatment, research and science, is seeking participants for a new study on in vitro maturation (IVM).
- Conditions
- Healthy, PCOS, PCOS (Polycystic Ovary Syndrome), Ovarian Reserve
- Trial name
- NCT06633120
- Testing
- IVM
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colorado Center for Reproductive Medicine
PCOS, Obesity
Liraglutide Treatment in Obese Infertile PCOS Women
Liraglutide, a hypoglycemic drug, can reduce weight and improve insulin resistance while stabilizing blood glucose metabolism without increasing the risk of hypoglycemia, and has been approved by the State Food and Drug…
- Conditions
- PCOS, Obesity, Infertility
- Trial name
- LITOP (NCT06742710)
- Testing
- Liraglutide and metformin, Metformin
- Where
- 3 sites in China
- Volunteers
- 890 people
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome
Clomiphene Citrate (CC) Co-treatment With HP Urinary FSH vs HP Urinary FSH in CC-resistant PCOS
To test whether adding small doses of HP urinary FSH to standard regimen of clomiphene citrate in clomiphene resistant PCOS well yield better results in terms of better ovulation rate,lower follicle number, less consumption of HP…
- Trial name
- NCT01212263
- Testing
- Step-up HP u FSH, Clomiphine citrate plus low dose uFSH
- Where
- Egypt
- Volunteers
- 174 people
- Sponsor
- Mansoura Integrated Fertility Center
Hypogonadism; Ovarian, Female Infertility
Effect of 12 Weeks of Acupuncture on AMH and COH in Low Responder Patients
the investigators want to study whether 12 weeks of acupuncture has any effect on AMH and the ovarian reserve in women with low ovarian reserve (low responders).
- Trial name
- NCT03080584
- Testing
- acupuncture
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Dansk Fertilitetsklinik
Amenorrhea, Dysmenorrhea
Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants
This project is examining the reproductive effects of exposure to certain compounds that are suspected to act on the endocrine system, e.g. they may act like or interfere with hormones such as estrogen.
- Conditions
- Amenorrhea, Dysmenorrhea, Oligomenorrhea, Anovulation
- Trial name
- NCT00011388
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Infertility
Influence of a Prematuration Culture With a Phosphodiesterase-3 Inhibitor (PDE3-I) on Embryonic Aneuploidy Rate and Developmental Potential
A single centre randomised controlled trial investigating the influence of a novel prematuration system (PMS) using a phosphodiesterase-3 inhibitor for in-vitro maturation of oocytes - pilot study.
- Trial name
- NCT00822874
- Testing
- prematuration culture
- Where
- Belgium
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Primary Ovarian Insufficiency, Infertility
In Vitro Follicle Activation
The purpose of this study is to evaluate the effectiveness of an experimental treatment, known as in vitro activation (IVA) of dormant ovarian follicles, for infertility in women diagnosed with primary ovarian insufficiency (POI).
- Trial name
- IVA (NCT02496598)
- Testing
- In Vitro Follicle Activation (IVA), Follicle Activation
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- National Foundation for Fertility Research
Perimenopausal Disorder, Menopause
Inovium Ovarian Rejuvenation Trials
The Inovium Ovarian Rejuvenation Treatment is a PRP-based autologous treatment used in combination with a stimulated IVF sequence and Pre-Implantation Genetic Screening to treat infertility in women experiencing menopause…
- Conditions
- Perimenopausal Disorder, Menopause, Menopause, Premature, Menopause Related Conditions
- Trial name
- NCT03178695
- Testing
- Autologous PRP injection into human ovarian tissue
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ascendance Biomedical
Polycystic Ovary Syndrome
Effect of Ultrasound Cavitation Versus Electrolipolysis on Obese Infertile Women With Polycystic Ovarian Syndrome
This study aims to determine the difference between the effect of ultrasound cavitation and electrolipolysis on obese infertile women with polycystic ovarian syndrome.
- Trial name
- NCT06490419
- Testing
- Electrolipolysis, ultrasound cavitation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Polycystic Ovary Syndrome, Infertility, Female
Micronutrient Supplementation in PCO-syndrome
The role of micronutrients in fertility has recently gained increased attention. In women who suffer from polycystic ovary syndrome (PCOS) and infertility, we aim to test the impact of a standardized, multinutrient…
- Conditions
- Polycystic Ovary Syndrome, Infertility, Female, Micronutrient Deficiency
- Trial name
- NCT03306745
- Testing
- Profertil female, Folic acid 400 mg
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Sub Fertility, Female, Fertility Disorders
Feasibility and Safety of Fasting in Fertility Treatment
This exploratory study investigates fasting as a potential supportive therapy in infertility treatment for women suffering from infertility
- Conditions
- Sub Fertility, Female, Fertility Disorders, Cycle Disorders Menstrual, Ovulation Disorder
- Trial name
- KiWuA (NCT04942457)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Charite University, Berlin, Germany
Infertility, Premature Ovarian Failure
Modified Natural Cycle Offers a Chance of Pregnancy in Patients With Poor Response and High Basal FSH
The purpose of this study is to evaluate the effectiveness of a modified natural cycle in patients with previous poor response to infertility drugs and high basal FSH, prior to proceeding to oocyte donation or abandoning…
- Trial name
- NCT00417157
- Testing
- recombinant FSH (Puregon, Organon, The Netherlands), GnRH antag: Ganirelix (Orgalutran, Organon, The Netherlands), hCG (Pregnyl, Organon, The Netherlands)
- Where
- Greece
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Eugonia
Polycystic Ovary Syndrome, Infertility
Progestin-induced Endometrial Shedding in PCOS (The PIES in PCOS Study)
Progestin-induced endometrial shedding (PIES) followed by clomiphene citrate is fertility treatment of choice in anovulatory women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT01718444
- Testing
- Progestin, Clomiphene Citrate
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Illinois Chicago
Infertility and at High Risk of OHSS
Repeated Injection of GnRH Agonist to Reduce Ovarian Hyperstimulation Syndrome
Gonadotropin releasing hormone (GnRH) agonist is sufficient for triggering final oocyte maturation in GnRH antagonist protocol and can significantly reduce incidence of ovarian hyperstimulation syndrome (OHSS) in high-risk…
- Trial name
- NCT02022241
- Testing
- triptorelin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chenshiling