Clinical trials: Endocrine Malignancy
Ovarian Cancer, Healthy Volunteers
Safety and Biodistribution of Technetium Tc 99m EC20 in Normal Volunteers and Ovarian Cancer Patients
Open-label, single-center, single-treatment group, baseline-controlled (for safety) study of the safety and biodistribution of Technetium Tc 99m EC20 in four normal subjects and four subjects with known or suspected ovarian…
- Trial name
- NCT01689636
- Testing
- Tc 99m EC20
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Endocyte
Overweight and Obesity, Men
Evaluation of a Supplement for Weight Management in Obese and Overweight Individuals
The purpose of this trial is to examine the effects of a novel, orally consumed dietary supplement (composed of naturally occurring components) on weight management and metabolic rate in individuals who are overweight or obese…
- Conditions
- Overweight and Obesity, Men, Women
- Trial name
- NCT03812211
- Testing
- Active Supplement
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- McMaster University
Ovarian Cancer
Transvaginal Ultrasonography as a Screening Method for Ovarian Cancer
This is a large, prospective, single-arm cohort study of transvaginal ultrasonographic screening for ovarian cancer in intermediate to high-risk women from Kentucky.
- Trial name
- NCT04473833
- Testing
- Serial Transvaginal Ultrasonography
- Where
- United States
- Volunteers
- 65,000 people, healthy volunteers welcome
- Sponsor
- John R van Nagell
Polycystic Ovary
Serum Fetuin Level in Polycystic Ovary Syndrome
polycystic ovary syndrome is a common gynecological problem
- Trial name
- NCT03819998
- Testing
- measurement of Fetuin-A level in serum
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Ovarian Cancer, Borderline Ovarian Tumors
Treg, Th17 Cells, NKT in Epithelial Ovarian Tumor
The aim of the study was to estimate the percentage and of Treg, Th17 and NKT in peripheral blood and the tissue of the epithelial ovarian tumor and relationship with blood serum level of HE4, CA125, as well as algorithm ROMA.
- Conditions
- Ovarian Cancer, Borderline Ovarian Tumors, Benign Ovarian Tumor, Unexplained Infertility
- Trial name
- NCT03779399
- Testing
- Assessment of percentage of Treg, Th17, NKT and serum level of HE4, CA125 and ROMA.
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Ovarian Cancer
Phase 1 Dose Escalation of ArtemiCoffee
This is a phase I dose-escalation study of Artemisia annua (Aa) in patients with advanced ovarian cancer who have completed front-line chemotherapy with carboplatin and paclitaxel.
- Trial name
- NCT04805333
- Testing
- Artemisia annua 450mg, Artemisia annua 900mg, Artemisia annua 1350mg
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Frederick R. Ueland, M.D.
Obesity, Polycystic Ovary Syndrome
Effect of Diet Plus Sibutramine on Hormonal and Metabolic Features in Overweight and Obese Women With PCOS
Studies on the effect of sibutramine, an anti-obesity drug, on hormonal and metabolic features of women with polycystic ovary syndrome (PCOS) are lacking.
- Trial name
- NCT00463112
- Testing
- Sibutramine
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hippocration General Hospital
Ovarian Cancer
Blood Test for Ovarian Cancer Associated Auto Antibodies
Intend of use: A blood test for Cancer Associated Antibodies (CAAA) is an aid in initial diagnosis of ovarian cancer in women with suspected ovarian pathology as detected by primary diagnostic techniques.
- Trial name
- NCT01334437
- Where
- Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eventus Diagnostics Ltd
Infertility
Influence of a Prematuration Culture With a Phosphodiesterase-3 Inhibitor (PDE3-I) on Embryonic Aneuploidy Rate and Developmental Potential
A single centre randomised controlled trial investigating the influence of a novel prematuration system (PMS) using a phosphodiesterase-3 inhibitor for in-vitro maturation of oocytes - pilot study.
- Trial name
- NCT00822874
- Testing
- prematuration culture
- Where
- Belgium
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cortisol Excess, Stress, Psychological
Effects of "Vitamin N" Nature Immersion Therapy on Stress Levels in Health Care Workers in the City of Bogotá
Recent studies on health personnel in Colombia have evidenced the considerable increase in the levels of stress and anxiety, among other psychological disorders, as a product of the COVID-19 pandemic that is being experienced…
- Conditions
- Cortisol Excess, Stress, Psychological, Anxiety, Epigenetic Disorder
- Trial name
- NCT05315388
- Testing
- Immersion therapy in nature - Vitamin N
- Where
- Colombia
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Jeadran N. Malagón-Rojas
Thyroid, Papillary Thyroid Cancer
A Study of Online Follow-up in Patients With Papillary Thyroid Cancer
The randomized, actively controlled, non-inferiority trial is scheduled to begin in August 2024 and run through August 2026. Inclusion criteria: (1) has undergone microwave ablation of thyroid or thyroidectomy (including…
- Trial name
- NCT06800482
- Testing
- online outpatient follow-up
- Where
- China
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University
Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome: Impact of Flaxseed Supplementation
The overall aim of this study is to explore the effects of flaxseed supplementation and determine whether it is a feasible and potentially effective dietary intervention among women with polycystic ovarian syndrome (PCOS).
- Trial name
- NCT00693082
- Testing
- flaxseed
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Duke University
Pancreatic Ductal Adenocarcinoma, Stage I Pancreatic Cancer AJCC v8
Monitoring Heart Rate Variability for the Early Detection of Pancreatic Cancer
This study examines heart rate monitoring variability for the early detection of pancreatic cancer. Pancreatic cancer is a very difficult disease to detect early.
- Conditions
- Pancreatic Ductal Adenocarcinoma, Stage I Pancreatic Cancer AJCC v8, Stage IA Pancreatic Cancer AJCC v8, Stage IB Pancreatic Cancer AJCC v8
- Trial name
- NCT04400903
- Testing
- Activity Monitor, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Ovarian Cancer, Breast Cancer
Comprehensive Outcomes for After Cancer Health
This study intends to explore feasibility, acceptability, and outcomes related to the use of a digital health coaching intervention for individuals who have completed primary therapy for cancer.
- Conditions
- Ovarian Cancer, Breast Cancer, Lung Cancer, Gastric Cancer
- Trial name
- COACH (NCT05349227)
- Testing
- Digital Health Coaching Program, Fitbit
- Where
- 7 sites in United States
- Volunteers
- 625 people, healthy volunteers welcome
- Sponsor
- Pack Health
Sleep Disorders
Study to Investigate Safety, Tolerability, Pharmacokinetics and Cardiac Function After Repeat Doses of SB-649868 in Healthy-volunteers
The purpose of this study is to determine whether SB-649868 is safe, tolerable after repeated administrations in adult and elderly healthy volunteers. Pharmacokinetics and effects on cardiac function of repeated doses are studied
- Trial name
- NCT01030939
- Testing
- SB-649868
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Metabolic Syndrome, Hypogonadism
Symptoms and Clinical Signs of Hypogonadism in Testicular Cancer Survivors
The purpose of this study is to investigate the prevalence of signs and symptoms of hypogonadism in three groups of testicular cancer survivors.
- Conditions
- Metabolic Syndrome, Hypogonadism, Cardio-vascular Disease
- Trial name
- NCT02240966
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Thyroid Cancer
The Role of Midkine in Diagnosis of Thyroid Cancer
1. Evaluation of the role of serum midkine in differentiating malignant from benign thyroid nodule 2. studying the level of serum midkine in relation to different thyroid cancer stages
- Trial name
- NCT03978351
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Assiut University
PCOS, Reproductive Age
Adipokines in Polycystic Ovary Syndrome
The aim of the study is to compare the concentrations of leptin, resistin, and omentin-1 in women across three research groups: those with polycystic ovary syndrome without insulin resistance, those with polycystic ovary syndrome…
- Trial name
- NCT06793072
- Testing
- Leptin concentration in blood serum, Resistin concentration in blood serum, Omentin-1 concentration in blood serum
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
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