Clinical trials: Endocrine Malignancy
Pancreatic Diseases, Pancreatic Neoplasms
POstopeRative Standardization of Care: THe Implementation of Best Practice After Pancreatic Resection
This Nationwide stepped-wedge cluster randomized trial is designed to evaluate if the implementation of a best practice algorithm for postoperative care results in a decrease in incidence of major complications and death after…
- Conditions
- Pancreatic Diseases, Pancreatic Neoplasms, Pancreatic Cancer, Pancreatitis
- Trial name
- PORSCH (NCT03400280)
- Testing
- Best practice algorithm for postoperative care
- Where
- 17 sites in Netherlands
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Healthy, Men
Study of Spermatogenesis Suppression With DMAU Alone or With LNG Versus Placebo Alone in Normal Men
This is a Phase IIa multicenter, double-blind, placebo-controlled study in healthy men to evaluate the spermatogenesis suppression after oral administration of Dimethandrolone Undecanoate (DMAU) alone or with Levonorgestrel (LNG)…
- Conditions
- Healthy, Men, Male Contraception
- Trial name
- NCT03455075
- Testing
- Dimethandrolone-Undecanoate, Levonorgestrel 0.03 MG
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Premier Research
Polycystic Ovary Disease
"KETOGENIC MEDITERRANEAN VERSUS HYPOCALORIC BALANCED DIET ON POLYCYSTIC OVARIAN ADOLESCENTS"
study was designed to determine the effect of ketogenic Mediterranean diet versus hypocaloric balanced diet on adolescent female with polycystic ovary disease.
- Trial name
- keto- MEDITERR (NCT06610812)
- Testing
- KETOGENIC MEDITERRANEAN diet, hypo-caloric diet:, moderate aerobic exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MTI University
Breast Cancer Female
Predictors of Adjuvant Endocrine Therapy in Women With Breast Cancer
Breast cancer is the leading cancer diagnosed in women and the second cause of cancer death. Of all racial/ethnic groups in the US, Black women have the highest rate of breast cancer deaths.
- Trial name
- WHIP (NCT02992730)
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Thyroid Cancer
SREBP1 as a Potential Biomarker Promotes Cell Proliferation and Invasion in Thyroid Cancer
In this study, the investigators detected the expression of SREBP1 in thyroid cancer tissues, explored the biological functions of SREBP1 in thyroid cancer cells.
- Trial name
- NCT04072731
- Testing
- pathologic
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- People's Hospital of Zhengzhou University
Vitamin D Deficiency
How Much Vitamin D is Required to be Protective Against Deficiency During the Winter Months?
Vitamin D is essential to bone health. In Canada, it is obtained by sunlight exposure of the skin (between April and October) or by a few foods such as fatty fish, eggs or fortified milk and margarine.
- Trial name
- NCT01437696
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- McGill University
Ovarian Cancer
Elecsys HE4 Chinese Reference Value Study
Aim of this study is to provide specimens for establishing reference values of HE4 in an apparently healthy Chinese population using the Roche Elecsys HE4 assay tested on variety of Elecsys and cobas brand immunoassay analyzers.
- Trial name
- NCT01738269
- Where
- 9 sites in China
- Volunteers
- 2,351 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Obesity, Type 2 Diabetes
Strength and Nutrition Outcomes for Latino Adolescents
We are conducting an intervention study to examine the effects of a 16-week exercise and diet interventions on prevention of disease, specifically type 2 diabetes and heart disease, in Latino youth.
- Conditions
- Obesity, Type 2 Diabetes, Cardiovascular Risk, Cancer
- Trial name
- SANO LA (NCT00697580)
- Testing
- Nutrition, Strength Training & Nutrition, Circuit Training & Nutrition
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Men, Health Behavior
POWERPLAY: Promoting Men's Health at Work
With funding from the Candian Cancer Society, the Men's Healthy Eating Active Living (MHEAL) project began the development, evaluation, and optimization of a program called POWERPLAY to promote men's health at work.
- Conditions
- Men, Health Behavior, Health Knowledge, Attitudes, Practice, Cancer
- Trial name
- POWERPLAY (NCT03548077)
- Testing
- POWERPLAY
- Where
- Canada
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Disorders of Sex Development (DSD), Pediatric and Adolescent Cancers of the Genital Tract
Data Collection Study of Pediatric and Adolescent Gynecology Conditions
Background: Gynecologic conditions are those that are related to the reproductive system. They can be reproductive gland disorders or reproductive system tumors. They can also be inborn anomalies of the reproductive tract.
- Conditions
- Disorders of Sex Development (DSD), Pediatric and Adolescent Cancers of the Genital Tract, Reproductive Endocrine Conditions in Puberty, Structural Gynecologic Conditions Including Vulvar and Vaginal Conditions
- Trial name
- NCT04717349
- Where
- United States
- Volunteers
- 11,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Ovarian Cancer, Endometrial Cancer
An Exploratory Study of Detection of Endometrial and Ovarian Cancers in Vaginal Samples Retrieved by the Ellele Sampling Device
An exploratory study of early detection and investigation of gynaecological diseases Throughout a woman's life, she may need tests that can feel uncomfortable, such as a smear test or a biopsy taken through the vagina.
- Trial name
- NCT07429799
- Testing
- Ellele Sampling Device
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ellele Health
Pancreatic Neoplasms
The Results of Pancreatic Operations After the Implementation of Multidisciplinary Team Conference (MDT):
Background: Centralization has improved the outcome of complex operations including cancer surgery. Moreover, the implementation of multidisciplinary team conferences (MDT) has ameliorated the decision making, but the impact on…
- Trial name
- NCT04237441
- Testing
- number of participants with surgical complications
- Volunteers
- 7,294 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer, Colorectal Cancer
UMCC 003 Cancer-Related Protein Biomarkers in Blood and Tumor Tissue of Patients With Cancer
RATIONALE: Studying samples of blood and tumor tissue in the laboratory from patients with cancer and blood from healthy participants may help doctors learn more about changes that may occur in DNA and identify biomarkers related…
- Conditions
- Breast Cancer, Colorectal Cancer, Esophageal Cancer, Liver Cancer
- Trial name
- IRB 2000-294 (NCT00900094)
- Testing
- fluorescence in situ hybridization, polymerase chain reaction, protein expression analysis
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
BCL2 Gene mRNA Overexpression
Validation of Useful Markers Generated by Next Generation Bio-data Based Genome Research and Cohort Study
Multiple biomarker development through validation of useful markers generated by next generation bio-data based genome research and cohort study
- Trial name
- miRNA_Chip (NCT02807896)
- Where
- South Korea
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- CHANGHEE LEE
Pancreatic Cancer, Head and Neck Cancer
Creation of the BioBank, Early Detection and Discovery Biomarkers
To establish a multidisciplinary research structure for tissue repository that facilitates projects that bridge specialties that normally may or may not interact.
- Conditions
- Pancreatic Cancer, Head and Neck Cancer, Breast Cancer
- Trial name
- NCT00901680
- Where
- United States
- Volunteers
- 3,028 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Ovarian Cancer
Primary Debulking Surgery Including Bowel Resection in Advanced Stage Ovarian Cancer Using Caiman® Technology
Longitudinal prospective study on primary debulking surgery including bowel resection in advanced stage ovarian cancer patients using Caiman® technology
- Trial name
- CAIMAN (NCT03219242)
- Testing
- Caiman® device
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Ovarian Cancer, Peritoneal Carcinomatosis
Imaging of Peritoneal Carcinomatosis From Ovarian Carcinoma Patients
The purpose of this study is to determine if NIF fluorescent imaging is an effective approach to detect the gross ovarian tumoral tissues and peritoneal implants in Ovarian cancer patients.
- Trial name
- OV-AP-ICG-IV (NCT01834469)
- Testing
- iv injection of ICG
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Ovarian Cancer
CA125 and Ultrasound in Detecting Ovarian Cancer in Postmenopausal Women
RATIONALE: Screening tests may help doctors detect ovarian cancer early when the survival is much more encouraging. It is not yet known whether a CA125-based or ultrasound strategy is more effective in detecting ovarian cancer…
- Trial name
- UKCTOCS (NCT00058032)
- Testing
- screening questionnaire administration, annual screening
- Volunteers
- 202,638 people, healthy volunteers welcome
- Sponsor
- University College, London
Pancreatic Cancer, Thyroid Cancer
Integrated Cancer Repository for Cancer Research
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer…
- Conditions
- Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer
- Trial name
- iCaRe2 (NCT02012699)
- Where
- 42 sites in United States
- Volunteers
- 999,999 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Hereditary Breast and Ovarian Cancer Syndrome
Statewide Communication to Reach Diverse Low Income Women
Recruitment for prevention, and early detection among health disparities populations represents a major challenge in chronic disease control.
- Trial name
- NCT02956681
- Testing
- Intervention Group, Delayed Intervention Group
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
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