Clinical trials: Endocrine System Diseases
Cholesterol, Lipid Profile
Effect of Curd Cheese on Metabolic Health in Adults
This randomized controlled trial aims to evaluate the effects of a diet supplemented with curd cheese on anthropometric measurements, glycemia, and lipid profile in overweight adults.
- Conditions
- Cholesterol, Lipid Profile, Diabete Mellitus
- Trial name
- NCT07676838
- Testing
- Curd Cheese Supplemented Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Süleyman Kılıç
Type 2 Diabetes Mellitus (T2DM), Overweight , Obesity
A Study to Evaluate Different Administration Conditions and the Food Effect of MWN109 Tablets in Chinese Participants
This is a randomized, open-label, multiple-dose study to evaluate the effects of different volumes of administration water, post-dose fasting duration, and high-fat diet on the pharmacokinetics of the 15 mg dose of MWN109 tablets…
- Trial name
- NCT07801326
- Testing
- MWN109 Tablets
- Where
- China
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Type 1 Diabetes
Hypoglycemia Associated Autonomic Failure in Type 1 DM, Q5
When a patient with Type 1 diabetes exercises, he or she is more prone to low blood sugar, or hypoglycemia. It is known that antecedent exercise can blunt defense responses, called counterregulatory responses to subsequent…
- Trial name
- NCT00605774
- Testing
- epinephrine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University
Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS)
Efficacy of Lavender Aromatherapy on Anxiety and Pain Reduction During Awake Otolaryngologic Procedures
The purpose of this study is to evaluate the efficacy of lavender aromatherapy in adult patients undergoing awake otolaryngologic procedures in the outpatient clinic setting.
- Conditions
- Inferior Turbinate Hypertrophy, Chronic Rhinosinusitis (CRS), Rhinitis, Vasomotor, Thyroid Nodules
- Trial name
- NCT07299474
- Testing
- Lavender Aromatherapy
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Cystic Fibrosis
Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis
In this exploratory study, the hormonal responses to a mixed meal will be examined in people with cystic fibrosis. The aim of this study is to find correlates with impaired glucose tolerance that is associated with this…
- Trial name
- NCT06163482
- Testing
- Mixed meal
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Diabetes Mellitus, Type II
Effect of SLC30A8 rs13266634 Genetic Polymorphism on Zinc Supplementation and Glycemic Control in Egyptian Patients With Type 2 Diabetes Mellitus
Study whether SLC30A8 rs13266634 polymorphism is associated with type 2 diabetes mellitus (T2DM) susceptibility in Egyptian patients and study effect of Zn supplementation on glycemic control in patients with type 2 diabetes
- Trial name
- SLC30A8 (NCT03112382)
- Testing
- zinc supplement plus vitamin A and E, vitamin A and E
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Adrenoleukodystrophy
Newborn Screening for Adrenoleukodystrophy
To test if the routine newborn screening dried blood spots can be used to test if elevation of C26:0 lysophosphatidylcholine (C26:0-lyso-PC), a status indicating adrenoleukodystrophy (ALD)
- Trial name
- NCT02952482
- Testing
- newborns testing for ALD
- Where
- Taiwan
- Volunteers
- 45,796 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ovarian Cancer
Biobehavioral and Sociodemographic Characteristics of Long Term Survivors of Ovarian Cancer
The goal of this research study is to learn about diet and exercise habits, emotions, and social support in the lives of women with ovarian cancer.
- Trial name
- NCT02043158
- Testing
- Questionnaire, Interview
- Where
- 5 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Chronic Ulcer, Venous Ulcer
Efficacy of PICO Single-use System in Chronic Ulcers
A clinical trial will be carried out comparing the efficacy of PICO system based on negative pressure therapy (NPT) in adults with chronic ulcers compared to conventional treatments.
- Conditions
- Chronic Ulcer, Venous Ulcer, Diabetic Foot Ulcer, Pressure Injury
- Trial name
- NCT05877378
- Testing
- Single-use negative pressure therapy (PICO)
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
FNA, microRNA
microRNA in Thyroid Cancer
Thyroid cancer is the most common endocrine malignancy and its incidence is rapidly increasing. Palpable thyroid nodules are very common, affecting up to 5% of the general population.
- Conditions
- FNA, microRNA, Thyroid Cancer, Thyroid Nodule
- Trial name
- NCT01964508
- Testing
- Fine needle aspiration
- Where
- Israel
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cirrhosis, Diabetes Mellitus
Efficacy of Esmolol in the Identification of Cardiovascular Disorders by Cirrhosis, Diabetes Mellitus and Cardiotoxic Treatments
The purpose of this study is to assess the superiority of esmolol echocardiography over conventional echocardiography in the diagnosis of subclinical myocardial involvement associated with diabetes mellitus 2, cirrhosis and…
- Conditions
- Cirrhosis, Diabetes Mellitus, Oncologic Disorders
- Trial name
- CIBERbBECHO (NCT05769868)
- Testing
- Esmolol Injection [Brevibloc]
- Where
- 6 sites in Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Diabetes Mellitus
Nutritional Habits Among People With and Without Diabetes in Upper Egypt
Type2 Diabetes is a serious chronic disease associated with numerous complications. It is pandemic disease due to worsening of diatery habits and westernization of diet.
- Trial name
- NCT06722274
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Assiut University
Type 2 Diabetes
The Glycemic Response Elicited by Beta-glucans of Different Physical Properties and Form
The ability of oat β-glucan to lower postprandial glycemic responses has been attributed to the viscosity of the solution in which the fibre is solubilized.
- Trial name
- NCT01610518
- Testing
- oat beta-glucan
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Guelph Food Research Centre
Hypothyroidism, Anesthesia, General
Effect of Brain GABA Metabolite Amount to Propofol Utilisation Under TIVA in Hypothyroid Patient
Introduction: GABAergic synaptic transmigration in the anterior cingulate (ACC) cortex of hypothyroid rats has been demonstrated by electrophysiologic recordings.
- Conditions
- Hypothyroidism, Anesthesia, General, Propofol Dosage, Magnetic Resonance Imaging (MRI)
- Trial name
- BrainGABA (NCT06649318)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duzce University
Precursors to PCOS
Research Study for Children With a Mother or Sister With Polycystic Ovary Syndrome
In this study, we want to find out more about polycystic ovary syndrome(PCOS). This is a common problem in about 7% of teenage girls. Problems may include irregular periods, extra hair on the face, chest and back areas.
- Trial name
- PCOS (NCT00559390)
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pregnancy Related, Thyroid
Safety and Efficacy of Empiric Levothyroxine (LT4) Dose Increase Versus Individualized LT4 Dose Increase in Hypothyroid Women During Pregnancy
In women who require thyroid hormone replacement medication, the investigators will compare 2 ways to adjust thyroid medication during pregnancy to determine superiority in maintaining optimal blood levels of thyroid hormone.
- Trial name
- NCT03115515
- Testing
- levothyroxine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Type 2 Diabetes
A Relative Bioavailability Study of Metformin HCL Tablets, 1000 mg Under Fasting Conditions
The purpose of this study is to demonstrate the relative bioequivalence of Metformin HCL Tablets, 1000 mg under fasting conditions.
- Trial name
- NCT00865033
- Testing
- Metformin HCL Tablets, 1000 mg Sandoz, Glucophage 1000 mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sandoz
Gestational Diabetes, Pregestational Diabetes
Maternal Diabetes in Newborns With Hearing Loss
This study aims to investigate the presence and characteristics of maternal diabetes as a risk factor in newborns with hearing loss. Hearing loss is one of the most common congenital anomalies among newborns.
- Conditions
- Gestational Diabetes, Pregestational Diabetes, Hearing Loss
- Trial name
- GDM (NCT05152589)
- Testing
- hearing test
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Obesity, Healthy
Effect of Bile Acids on Satiety, Cell Function and Body Weight in Patients With Obesity and Abnormal Satiety Phenotype
The purpose of this research is to study the effect of the study drug (a conjugated bile acid dietary supplement) or placebo on cell function, hormones and body weight.
- Trial name
- NCT05314374
- Testing
- Ileocolonic-release conjugated bile acid
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hypercholesterolemia, Hypertension
Evaluating "Health at Every Size"(HAES) as an Alternative Obesity Treatment Model
Increasingly more individuals are trying to lose weight. Indeed, many women, regardless of their size, experience a life-long battle and preoccupation with their weight.
- Conditions
- Hypercholesterolemia, Hypertension, Depression, Diabetes Mellitus, Type 2
- Trial name
- NCT00074633
- Testing
- Health at Every Size (HAES), Diet (Traditional, moderate energy restriction)
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
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