Clinical trials: Endocrine System Disorder
Healthy
Effects of Intranasal Oxytocin and Vasopressin on Social Behavior and Decision Making
The purpose of this study is to investigate the role of a one-time intranasal administration of the oxytocin, vasopressin, or placebo on prosocial decision making such as cooperation and competition in a healthy population of…
- Trial name
- NCT02526914
- Testing
- Intranasal Oxytocin, Intranasal vasopressin
- Where
- Israel
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- David Mankuta
Gestational Diabetes Mellitus
Effect of Fasting Time Before Cesarean Section on Neonatal Blood Glucose in Pregnant Women With Gestational Diabetes Mellitus
Objective: To observe the effect of different fasting time on neonatal blood glucose in pregnant women with gestational diabetes mellitus (GDM).
- Trial name
- NCT04915716
- Testing
- Peripheral blood glucose levels were monitored
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Obesity & Overweight, Circadian Rhythm Disorders
Effects of Akkermansia Muciniphila and Berberine Supplementation on Insulin Sensitivity in Night-shift Workers
Night shift work is associated with an increased risk of obesity, insulin resistance, and cardiometabolic disorders, largely due to circadian misalignment, disrupted sleep, and altered eating patterns.
- Conditions
- Obesity & Overweight, Circadian Rhythm Disorders, Gut Microbiota Modulation, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
- Trial name
- Shift2Health (NCT07440147)
- Testing
- Verum (A)
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Obesity, Diabetes
The Acute Effect of Malt Extract Versus Sucrose on the Response of Glucose and Insulin, Subjective Appetite Sensations and ad Libitum Energy Intake
Sucrose is the most used sweetener in beverage and foods in Denmark. Other sweeteners with other composition and amount of carbohydrates could be of interest in order to decrease the glucose and insulin responses after intake of…
- Trial name
- Harboe (NCT01615081)
- Testing
- The acute effect of malt extract versus sucrose on the response of glucose and insulin, subjective appetite sensations and ad libitum energy intake
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Prediabetes, Weight Loss
Diabetes Prevention Through Genetics, Familial History and Behavior Change
The goal of this clinical trial is to learn if adding a family engagement component to the standard Diabetes Prevention Program (DPP) improves outcomes for adults with prediabetes.
- Trial name
- NCT07815236
- Testing
- LEGACY DPP, DPP
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Type 2 Diabetes Mellitus, Binge-Eating Disorder
Preventing Type 2 Diabetes in Black Emergent Adult
Black Americans are disproportionately affected by diabetes, with nearly double the rates of type 2 diabetes mellitus (T2DM), compared to non-Hispanic White adults.
- Conditions
- Type 2 Diabetes Mellitus, Binge-Eating Disorder, Binge Eating, Obesity
- Trial name
- NCT06848244
- Testing
- Appetite Awareness Training (AAT), Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Premature Ovarian Failure
X-Chromosome Inactivation Status and Premature Ovarian Failure
Women who are affected with premature ovarian failure will exhibit skewed X-chromosome inactivation patterns compared to women with normal menstrual function (as defined by being pregnant), indicating a possible X-chromosome…
- Trial name
- NCT00295087
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Sexual Dysfunction, Endothelial Dysfunction
Effects of Diet-induced Weight Loss in Obese Men
This study aims to compare the efficacy of a partial meal replacement diet with a conventional diet, for inducing weight loss and improving metabolic and inflammatory profile, endothelial function, erectile function, sexual…
- Conditions
- Sexual Dysfunction, Endothelial Dysfunction, Quality of Life, Inflammation
- Trial name
- NCT01554865
- Testing
- Optifast, Conventional diet counseling
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Type 2 Diabetes Mellitus
Dose-response Effect of Pine Nut Oil as a Dual FFA1 and FFA4 Agonist on Glucose Tolerance in Healthy Humans.
Several free fatty acids receptors (FFARs) have been discovered. These have been implicated in metabolic processes and inflammation.
- Trial name
- NCT03305367
- Testing
- Hydrolyzed pine nut oil
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Foot Ulcer, Diabetic
Approaches to Foot Complication Prevention: A Survey of Diabetes Educators
The purpose of the survey is to assess the knowledge base, role in management, and resources available to diabetes educators regarding foot complication prevention within a variety of healthcare settings.
- Trial name
- NCT04400344
- Testing
- No intervention
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Podimetrics, Inc.
PreDiabetes
Study to Determine the Effect of Synbiotics in Patients With Pre-diabetes
The aim of this study is to examine the effect of Metabolic Rheostat™ and Butyrate Ultra on blood glucose levels after a liquid meal challenge in patients with prediabetes.
- Trial name
- Rheostat (NCT04428606)
- Testing
- Metabolic Rheostat, Butyrate Ultra
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zhaoping Li
Diabetes Mellitus
Assessment of Tissue Oxygenation Using Multispectral Imaging
In Canada, the age-standardized prevalence of diabetes is on the rise (increasing from 3.3% in 1998/99 to 5.6% in 2008/2009 Public Health Agency of Canada (July 2011)) and is almost 1 in 10 globally.
- Trial name
- NCT03516864
- Testing
- MIMOSA Imager, Kent Camera
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Bladder Cancer, Diabetes
BLADDER CANCER SCREENING AMONG DIABETIC PATIENTS
patients om metformin from diabetic clinic were checked for bladder cancer
- Trial name
- NCT02505516
- Testing
- metformin
- Where
- Ghana
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- UFUOMA MILLER FAKPOR
Obesity, Diabetes Mellitus, Type 2
Postprandial Profiles of Metabolites and Appetite-regulating Hormones in Plasma and Cerebrospinal Fluid
Overweight and obesity are rising in prevalence and becoming a growing threat to public health. Obesity is associated with an increased all-cause mortality, impaired quality of life, and numerous of disorders.
- Trial name
- NCT06115304
- Testing
- Large liquid meal, spinal catheter and venous line
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mikkel Bring Christensen
Adrenal Cortex Neoplasms
Cardiovascular Risk in Patients With Non-Functional Adrenal Incidentaloma
Between September 2006 and September 2008, 35 patients (32 women and 3 men; mean age 49years with adrenal incidentaloma (AI) were prospectively evaluated at the Department of Endocrinology and General Surgery of Istanbul…
- Trial name
- adrenal (NCT00768365)
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Obesity, Dyslipidemias
Effects of an Indoor Cycling Program on Cardio-Metabolic Factors in Women With Obesity and Normal Body Weight
The aim of the research is to (1) evaluate the potential clinical effectiveness and biological mechanisms of indoor cycling in the treatment of obesity and (2) provide-up-to-date evidence on the impact of indoor cycling in…
- Conditions
- Obesity, Dyslipidemias, Hypertension, Type 2 Diabetes
- Trial name
- NCT04456192
- Testing
- Indoor Cycling Interval Exercise Training
- Where
- Poland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Thyroid Nodular Disease
Microvascular Profiling of Nodules in the Thyroid Gland
The purpose of this study is to examine tiny blood vessels in different thyroid nodules using advanced ultrasound. In the long term, we hope this can help doctors better tell the difference between types of nodules and more…
- Trial name
- NCT07041307
- Where
- 2 sites in Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Thyroid, Thyroidectomy
Post Thyroidectomy Myocardial Function
Protocol Synopsis Protocol title: Post thyroidectomy myocardial function Purpose: Evaluation of the effects of total thyroidectomy on myocardial function Design: Prospective, single-center, cohort study Patient Population: Male…
- Conditions
- Thyroid, Thyroidectomy, Myocardial Function
- Trial name
- TECH (NCT03060499)
- Where
- Greece
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Metabolic Syndrome, Diabetes
Metabolic Phenotyping of Individuals Born Following Assisted Reproduction Techniques
This study is to compare the effects of high fat overfeeding on metabolic risk factors in children born though assisted reproduction technologies (ART) versus children conceived naturally (controls).
- Trial name
- IMPART (NCT01230632)
- Testing
- high fat overfeeding
- Where
- Australia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
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