Clinical trials: Endocrine System Disorder
Hypothyroidism, Hypertension
The Effect of SPU on Hormonal and Cardiometabolic Factors
The study examines the immediate effect of soleus pushup exercise on cardiometabolic and hormonal functions among hypothyroid patients.
- Conditions
- Hypothyroidism, Hypertension, Healthy Adult, Diabete Mellitus
- Trial name
- NCT07688824
- Testing
- Soleus pushup exercise
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Type 2 Diabetes Mellitus
Vitamin D Receptor Polymorphisms and Efficacy of Vitamin D-Fortified Yogurt Drink in Patients With Type 2 Diabetes
Study is a 12-week Double blind,controlled experiments designed to examine the possible effects of vitamin D receptor gene polymorphisms on the metabolic, inflammatory and oxidative stress markers in type 2 diabetic patients to…
- Trial name
- NCT01236846
- Testing
- Fortified Yogurt Drink, Plain Yogurt Drink
- Where
- 4 sites in Iran
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tirang R. Neyestani
Type 2 Diabetes, Obesity
Metabolomic Analysis of Hepatic Insulin Resistance
This is a pilot study to show that it is possible to identify the specific types of fats in blood, adipose tissue, and liver tissue.
- Trial name
- NCT01833403
- Testing
- Hyperinsulinemic-euglycemic clamp
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Diabetes, Mellitus, Type 1
A Study About Patient Decision Aids Designed to Help Parents and Guardians in Canada Make Evidence-informed, Values-congruent Decisions About Screening Children for Type 1 Diabetes and Follow-up Decisions.
This study will design and test patient decision aids to help parents and guardians in Canada make decisions about screening their children for type 1 diabetes.
- Trial name
- NCT07317973
- Testing
- Web-based patient decision aid, Standard materials
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Laval University
Diabetes, Metabolic Disease
Effectiveness of Pumpkin Seed Extract on Improving Blood Sugar Level in Subhealth Subjects
This randomized, double-blind, placebo-controlled, and parallel clinical study aims to investigate the effectivness of a pumpkin seed extract on blood sugar management in subhealth people.
- Trial name
- NCT05738655
- Testing
- Pumpkin seed extract (Low dose), Pumpkin seed extract (High dose)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Greenyn Biotechnology Co., Ltd.
Healthy
Glucophage Extended Release (GXR) China Bioequivalence Study (Nantong - Darmstadt)
The study will assess the bioequivalence between single doses of GXR manufactured in Merck Nantong China (test drug) and GXR manufactured in Merck Darmstadt Germany (reference drug) under fed and fasted state in healthy…
- Trial name
- NCT03566810
- Testing
- Test GXR, Reference GXR
- Where
- China
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Papillary Thyroid Carcinoma
Microwave Ablation and Surgical Resection for Micropapillary Thyroid Carcinoma
The study aimed to compare the efficacy and safety of papillary thyroid microcarcinoma (PTMC) treated with microwave ablation(MWA) and surgery resection (SR), and to explore the tumor characteristics suitable for each treatment…
- Trial name
- NCT04197960
- Testing
- Microwave ablation, Surgical resection
- Where
- China
- Volunteers
- 973 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Chronic Kidney Diease, Diabetes Mellitus
Chronic Kidney Disease and Metabolic Disorders in the Elderly
The goal of this observational study is to investigate the impact of metabolic comorbidities on outcomes in elderly Chinese adults, through two parallel sub-cohorts: one comprising elderly individuals without chronic kidney…
- Conditions
- Chronic Kidney Diease, Diabetes Mellitus, Hypertension, Hyperlipidemia
- Trial name
- NCT07494526
- Where
- 2 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Transgender Men, Blood Pressure
Mechanisms of Blood Pressure Dysfunction in Transmen Receiving Testosterone
The purpose of this research is to explore the effects of chronic androgen exposure on sympathetic nervous system activity (SNSA) and baroreflex control of blood pressure responses in transgender men (trans men) taking gender…
- Conditions
- Transgender Men, Blood Pressure, Hyperandrogenism
- Trial name
- NCT04524325
- Testing
- Trans men
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Diabetes Mellitus, Vascular Complications
Peripheral Vascular REactivity and Muscular Oxygenation in Diabetes Mellitus
Oxygen is required for an optimal muscle function. In patients with diabetes mellitus, hyperglycemia can cause vascular complications.
- Conditions
- Diabetes Mellitus, Vascular Complications, Mitochondrial Diseases
- Trial name
- PREMOD (NCT04226820)
- Testing
- examination: blood pressure assessment, examination: Flow Mediated Dilatation (FMD)-test, examination: handgrip exercise test with Near infrared spectroscopy (NIRS)-monitoring
- Where
- Belgium
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University Ghent
Precocious Puberty
Effect of Prevalence of BMI on Efficacy of Herbal Medicines in Girls' Sexual Precocity
Effect of Prevalence of Overweight and Obesity(Body Mass Index (BMI)) on Efficacy of herbal medicines(ZiYinXieHuo) in girls sexual Precocity
- Trial name
- NCT04665713
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Type 2 Diabetes Mellitus
Study of HTD4010 in Healthy Volunteers
To investigate safety and tolerability of HTD4010 after single ascending doses (SAD) in healthy volunteers
- Trial name
- NCT02538848
- Testing
- HTD4010
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- HighTide Therapeutics (Hong Kong) Limited
Diabetes Mellitus, Obesity
Jejunal Luminal and Colonic Mucosa-Associated Microbiota in Metabolic Diseases: Methods, Identification and Causalities
This clinical study will investigate Jejunal Microbiota in Metabolic Diseases (Je-MiMe, n=45) and Colonic mucosa-associated Microbiota in Metabolic Diseases (Col-MiMe, n=45).
- Conditions
- Diabetes Mellitus, Obesity, Metabolic Disease
- Trial name
- JE/COL-MIME (NCT05186389)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Diabetes Mellitus, Type 2
The Proportion of Patients With Non-diagnosed Diabetes Type 2
The aims of the study are to determine the prevalence of diabetes in subgroups of the population with certain characteristics (age, gender, socioeconomic status, geographical area of residence), to estimate the proportion of…
- Trial name
- Sadkorna (NCT04230382)
- Testing
- Diagnosis of diabetes (OGTT)
- Where
- Slovenia
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Insulin Resistance, Type 2 Diabetes
Insulin Resistance in the Control of Intestinal Lipid Metabolism
America's preferential consumption of high-fat/high-sugar foods is a driving force in the current epidemic of obesity and insulin resistance.
- Trial name
- NCT02020343
- Testing
- taste tests
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Impaired Glucose Tolerance, Peripheral Polyneuropathy
Electrodiagnostic Parameters in Patients With Impaired Glucose Tolerance and Diabetes Mellitus
The purpose of this study is to evaluate the distal sensory nerves of the feet, namely, the dorsal sural, medial dorsal cutaneous and medial plantar nerves, in patients with impaired glucose tolerance and diabetes mellitus type 2…
- Conditions
- Impaired Glucose Tolerance, Peripheral Polyneuropathy, DM
- Trial name
- NCT01094418
- Testing
- Nerve conduction studies ( NCS) of the peripheral nerves
- Where
- South Korea
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Gestational Diabetes Mellitus
Weight Changes During and After Pregnancy in Women With Gestational Diabetes
Gestational diabetes mellitus (GDM) is associated with short-term and long-term complications for infants and mothers. The management of GDM during pregnancy focuses on reducing risks to the infant associated with hyperglycemia.
- Trial name
- NCT02388958
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Type 2 Diabetes Mellitus
Type 2 Diabetes Controlled Eating Experiment
A short-term feeding study in type 2 diabetics manipulating the fat and caloric values of meals to assess both compensation and glucose control, both covertly and overtly.
- Trial name
- NCT00198926
- Testing
- covert v overt nutrition labeling, varying meal nutrition manipulation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diabetic Ketoacidosis
Subcutaneous Aspart Insulin to Treat Diabetic Ketoacidosis (DKA) and Beta-Hydroxybutyrate Testing in DKA
The purpose of this study is to determine whether insulin administered by a subcutaneous injection is effective in the treatment of a diabetic crisis and to determine if beta-hydroxybutyrate is useful to monitor during treatment…
- Trial name
- DKA (NCT00920725)
- Testing
- Insulin (Aspart Insulin [Novolog], Regular Insulin)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Type 2 Diabetes Mellitus
A Single and Multiple-Dose Study of MK-8521 in Healthy and Obese Males (MK-8521-002)
This study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of MK-8521. Part 1 primary hypothesis: Administration of single subcutaneous (SC) doses of MK-8521 is sufficiently safe and well- tolerated…
- Trial name
- NCT02055547
- Testing
- MK-8521 35μg, MK-8521 100μg, MK-8521 125μg
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
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