Clinical trials: Endocrine System Disorder
Diabetes
Assessment of Blood Glucose Monitoring Systems - Evaluation of Oxygen Dependency
Systems for blood glucose monitoring with glucose oxidase enzyme reaction on test strips can be affected by the partial pressure of oxygen of the blood sample.
- Trial name
- IDT-1326-IU (NCT01871831)
- Testing
- 6 blood glucose monitoring systems for self-testing
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut für Diabetes-Technologie Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm
Healthy Volunteers, Insulin Resistance
Polyphenols and Insulin Resistance
Diet and nutrition play an essential role in the development and the clinical expression of the most common health problems. Overeating and obesity induce oxidative stress, which has been proposed to be a pathogenic mechanism…
- Conditions
- Healthy Volunteers, Insulin Resistance, Type 2 Diabetes (T2D)
- Trial name
- POLYOXRESIST (NCT01478841)
- Testing
- polyphenol
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Diabetes, Healthy
Effect of Liraglutide on Gastrointestinal Absorption of Several Drugs and Potential Influence of Liraglutide on Intragastric pH
The trial is conducted in Europe. The aim of the trial is to investigate if there is any drug to drug interaction between liraglutide and atorvastatin (Lipitor®), lisinopril (Zestril®), griseofulvin and digoxin (Lanoxin®).
- Trial name
- NCT01518166
- Testing
- liraglutide, atorvastatin, lisinopril
- Where
- Sweden
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2, Hepatitis C
Effect of Co-administration of Metformin and Daclatasvir on the Pharmacokinetis and Pharmacodynamics of Metformin
A Randomized,Two-period, Crossover Study to Determine the Possibility of Drug-drug Interaction After Co-administration of Metformin and Daclatasvir Where Twenty Eligible Adult Subjects Will be Randomized to Receive Either…
- Conditions
- Diabetes Mellitus, Type 2, Hepatitis C, Drug Interactions
- Trial name
- NCT03686722
- Testing
- Metformin, Daclatasvir
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mohamed Raslan
Hypopituitarism
Acute Neuroendocrine Response to Intravenous Infusion of Diclofenac Sodium
The effects of acute administration of non-steroidal anti-inflammatory drugs (NSAIDs) on the neuroendocrine regulation of hydro-electrolytic metabolism are not precisely known to date.
- Trial name
- NCT05188131
- Testing
- Intravenous Infusion of Diclofenac Sodium
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- A.O.U. Città della Salute e della Scienza
Polycystic Ovarian Syndrome (PCOS)
Polycystic Ovarian Syndrome (PCOS) Biomarker Evaluation Study
The purpose of the study is to validate recently identified biomarkers for the identification of PCOS in adolecent and young adult women.
- Trial name
- PHOEBE (NCT06642831)
- Where
- Germany
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University Hospital Erlangen
Diabetes Mellitus, Cardiovascular Disease
SPREAD-NET: PRactices Enabling Adapting and Disseminating in the Safety NET
The investigators propose to compare the effectiveness of 3 strategies (low, medium, high intensity) at supporting CHCs' implementation of the ALL Initiative (an intervention shown to reduce patients' cardiovascular disease (CVD)…
- Trial name
- SPREAD-NET (NCT02325531)
- Testing
- Low support, Medium support, High support
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia
Bioequivalence Study Of Glucotrol XL 2.5 Mg Tablets
The objective of this study is to determine the bioequivalence of Glipizide GITS (Glucotrol XL) 2.5 mg tablets manufactured at the Brooklyn, New York facility versus tablets manufactured at the facility in Barceloneta, Puerto…
- Trial name
- NCT00550329
- Testing
- Glipizide GITS
- Where
- Singapore
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pregnancy Related, Hypothyroidism
TSHβX1 and D2 THR92ALA in Pregnancy
Thyroid diseases are pathologies that frequently affect pregnant women causing serious complications. This current research aims to find out whether the expression of TSHβX1 splice variant and D2 Thr92Ala polymorphism in the DIO2…
- Conditions
- Pregnancy Related, Hypothyroidism, Hyperthyroidism
- Trial name
- NCT03612908
- Where
- Mexico
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Materno-Perinatal Hospital of the State of Mexico
Aging, Sarcopenia
Resistance Exercise and Low-Intensity Physical Activity Breaks in Sedentary Time to Improve Muscle and Cardiometabolic Health
What are the effects of resistance exercise (RE) alone or RE plus low intensity physical activity (LPA) breaks in sedentary time (ST) on skeletal muscle health in older adults? What are the effects of resistance exercise (RE)…
- Conditions
- Aging, Sarcopenia, Disability Physical, Cardiovascular Diseases
- Trial name
- REALPA (NCT03771417)
- Testing
- Exercise Intervention
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Type 2 Diabetes, Hypertension
'Ai Pono Cooking Demonstrations
Native Hawaiians' traditional lifestyles and diets ensured the mutual health and well-being of the land and its inhabitants, which stand in stark contrast to the disproportionately high prevalence of diet-related, cardiometabolic…
- Conditions
- Type 2 Diabetes, Hypertension, Dyslipidemias, Overweight and Obesity
- Trial name
- NCT06526650
- Testing
- 'Ai Pono
- Where
- 2 sites in United States
- Volunteers
- 1,780 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Hypothyroidism
Quality of Life Among Egyptian Hypothyroid Patients
Assessment of quality of life among hypothyroid patients in Assiut University Hospital
- Trial name
- NCT05143918
- Testing
- assessment of quality of life using questionnaire
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Assiut University
Type 2 Diabetes
A Study to Evaluate the Pharmacokinetics and Safety of BR3409 and Co-administration of BR3409-1 and BR3409-2 in Healthy Volunteers Under Fasting Conditions
The purpose of this clinical study is to evaluate the pharmacokinetics and safety of BR3409 and co-administration of BR3409-1 and BR3409-2 in healthy volunteers Under Fasting Conditions
- Trial name
- NCT06879158
- Testing
- BR3409, BR3409-1, BR3409-2
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Type 2 Diabetes, Healthy
Type 2 Diabetes and the Effect of Probiotics
Insulin-resistance in type 2 diabetes is associated with chronic inflammation. Anti-inflammatory actions might increase sensitivity to insulin.
- Conditions
- Type 2 Diabetes, Healthy, Endotoxemia
- Trial name
- NCT00413348
- Testing
- Lactobacillus acidophilus NCFM
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetes, Diabetes Mellitus
The Impact of the Self-efficacy Building Nursing Program on Foot Self-care Confidence and Perceived Risk of Diabetes-related Foot Complications Among Diabetic Elderly Patients: A Randomized Virtual Based Trial
Abstract Background: Diabetes-related foot complications are a major cause of morbidity among elderly patients with diabetes, often exacerbated by inadequate self-care practices and low self-efficacy.
- Conditions
- Diabetes, Diabetes Mellitus, Foot Care
- Trial name
- foot self-care (NCT06973850)
- Testing
- The Self-Efficacy Building Nursing Program
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Genetics, Metabolism
Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS
The purpose of this research study is to examine whether specific genes (e.g. SLC16A11) affect how human beings respond to food and a medication that is commonly used to treat type 2 diabetes.
- Conditions
- Genetics, Metabolism, Type 2 Diabetes
- Trial name
- SCRAMBLED EGGS (NCT02087826)
- Testing
- Mixed Meal Tolerance Test, Metformin
- Where
- United States
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus
Improving Medical Training for the Care of Chronic Conditions
While medical training has increasingly included chronic care management, quality care necessitates education approaches that go farther.
- Trial name
- NCT00676208
- Testing
- Shared Medical Appointments
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PreDiabetes, Metabolic Syndrome
Strawberries and Risk of Diabetes in Adults
Strawberries can be categorized as a functional food based on results from several clinical trials in improving cardiometabolic health beyond providing nutrition.
- Trial name
- NCT05362968
- Testing
- Freeze-dried strawberry powder
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Type 2 Diabetes Mellitus (T2DM), Obesity Type 2 Diabetes Mellitus
Evaluation of Neuregulin-4 (NRG4) Levels in Obese and Non-Obese Patients With Type 2 Diabetes Mellitus
This prospective observational study aims to evaluate serum Neuregulin-4 (NRG4) concentrations in obese and non-obese adults with Type 2 Diabetes Mellitus (T2DM) and to investigate their association with obesity status, insulin…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Obesity Type 2 Diabetes Mellitus, Insulin Resistance
- Trial name
- NRG4-T2DM (NCT07734558)
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- GÜLDEN ANATACA
Gestational Diabetes
Immediate Postpartum Glucose Tolerance Testing
The objective of this study is to compare the accuracy of a 2hr glucose tolerance test administered during the postpartum hospitalization with the standard of care glucose tolerance testing (administered at 6 weeks postpartum).
- Trial name
- NCT04199676
- Testing
- Glucose tolerance test
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
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