Clinical trials: Endodontic Diseases
Pulpitis, Periapical Lesions
Success of Endodontic Treatment With Different Obturation Techniques and Sealer Cements
The present study aims to compare the radiographic success of endodontic treatment using Orstavik's criteria between two sealers: AH Plus (Dentsply DeTrey, Konstanz, Germany) and Neosealer Flo (Avalon Biomed, Bradenton, Florida…
- Conditions
- Pulpitis, Periapical Lesions, Periapical Periodontitis, Periapical Pathology
- Trial name
- NCT07019298
- Testing
- AH Plus (Dentsply Sirona, Charlotte, NC, USA), NeoSealer Flo, Continuous Wave Condensation
- Where
- Spain
- Volunteers
- 270 people
- Sponsor
- University of Siena
Rheumatoid Arthritis AND Apical Periodontitis
Effect of Endodontic Treatment on Inflammatory Markers, Disease Activity and Periapical Healing in Rheumatoid Arthritis Patients With Apical Periodontitis : A Prospective Interventional Study
SUMMARY TITLE: "Effect of endodontic treatment on inflammatory markers, disease activity and periapical healing in rheumatoid arthritis patients with apical periodontitis" RATIONALE: Chronic inflammation plays a pivotal role in…
- Trial name
- NCT06433232
- Testing
- ROOT CANAL TREATMENT
- Where
- India
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Endodontically Treated Teeth, Endodontic Underfill
No Code Artificial Intelligence to Detect Radiographic Features Associated With Unsatisfactory Endodontic Treatment
Developing neural network-based models for image analysis can be time-consuming, requiring dataset design and model training. No-code AI platforms allow users to annotate object features without coding.
- Conditions
- Endodontically Treated Teeth, Endodontic Underfill, Endodontic Overfill, Apical Periodontitis
- Trial name
- NCT06450938
- Testing
- AI guidance for finding radiographic features
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Tooth Injuries, Endodontically Treated Teeth
Regenerative Endodontic Treatment of Traumatised Teeth
Aim: The aim of this prospective study was to evaluate the treatment outcomes of regenerative endodontic technique (RET) for the management of traumatised non-vital immature teeth in children.
- Trial name
- NCT03045185
- Testing
- RET using Ciprofloxacin 100mg, and Metronidazole 100mg.
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Necrotic Pulp
Efficacy of Guedes-Pinto Paste and CTZ Paste in the Non-instrumental Endodontic Treatment of Primary Teeth
The maintenance of the deciduous tooth until its physiological exfoliation occurs is one of the main objectives of pediatric dentistry.
- Trial name
- NCT04587089
- Testing
- Irrigation, Filling with Guedes-Pinto Paste, Filling with CTZ Paste
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Irreversible Pulpitis, Endodontic Inflammation
A Clinical and Radiographic Evaluation of Low-Level Diode Laser Full Pulpotomy in Vital Permanent Teeth
In this study, patients with symptoms of irreversible pulpitis in mature permanent molars were treated with two pulpotomies techniques after random allocation in either 2 groups: Diode laser pulpotomy and traditional pulpotomy…
- Trial name
- NCT06176378
- Testing
- traditional pulpotomy, diode laser pulpotomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Root Canal Infection, Bisphosphonate-Associated Osteonecrosis
Root Canal Treatment Outcome in Patients Under Bisphosphonate Therapy
The aim of this study was to evaluate the survival rate and healing time of compromised teeth and seriously compromised teeth that were endodontically treated in patients which received bisphosphonate therapy .
- Conditions
- Root Canal Infection, Bisphosphonate-Associated Osteonecrosis, Periapical Abscess, Endodontically Treated Teeth
- Trial name
- NCT04399720
- Testing
- Root canal treatment
- Volunteers
- 111 people
- Sponsor
- University of Bologna
Apical Periodontitis
Retreatment and Diabetes
ABSTRACT This prospective, controlled, single-center clinical study aims to compare postoperative pain levels and analgesic consumption after nonsurgical endodontic retreatment in individuals with diabetes mellitus and…
- Trial name
- NCT07679880
- Testing
- root canal retreatment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Endodontic Disease
Postoperative Pain and Incidence of Extrusion Following the Use of Two Intra-canal Medications in Retreatment of Single Rooted Teeth
This study aims to compare the postoperative pain and incidence of extrusion of two intracanal medications in the retreatment of single-rooted teeth.
- Trial name
- NCT06913673
- Testing
- Bio-c Temp, Metapex
- Volunteers
- 30 people
- Sponsor
- Minia University
Periapical Periodontitis
Evaluation of Three Irrigants, Sodium Hypochlorite, Chlorhexidine and Combination of CHX+H2O2 in Endodontic Treatment.
This study will evaluate the synergistic effect of CHX + H2O2 when used as an irrigant during biomechanical preparation.in root canal treatment on periapical healing and compared with Chlorhexidine( CHX) and Sodium Hypochlorite…
- Trial name
- NCT04373018
- Testing
- Sodium hypochlorite, Chlorhexidine, Chlorhexidine + Hydrogen peroxide
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Endodontic Disease, Pulp Disease, Dental
The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament
The goal of this randomized clinical trial is to evaluate the capability of the material to exert bacterial reduction of diclofenac sodium versus of that calcium hydroxide paste when these materials are used as intracanal…
- Conditions
- Endodontic Disease, Pulp Disease, Dental, Intracanal Medication
- Trial name
- NCT06207253
- Testing
- Diclofenac Sodium, Calcium hydroxide
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Endodontic Disease, Postoperative Pain
Postoperative Pain in Endodontic Therapy
The goal of this clinical trial is to evaluate the change in postoperative pain in mandibular premolar and first molar teeth with asymptomatic apical periodontitis when using EDDY and passive ultrasonic irrigation activation…
- Trial name
- NCT06741592
- Testing
- EDDY Group, PUI Group
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ordu University
Periapical Disease
Effect of Piezoelectric Surgery on Quality of Life and Periradicular Healing After Endodontic Surgery
This study will compare the effect of piezo Vs bur on quality of life and healing after endodontic surgery.
- Trial name
- NCT04358887
- Testing
- piezoelectric surgery, conventional bur
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Endodontically Treated Teeth, Post Operative Pain
Effect of Intra-Canal Cryotherapy on Postoperative Pain After Endodontic Procedures
The goal of this randomised clinical trial is to evaluate the effect of cryotherapy on postoperative pain after primary and secondary root canal treatment.
- Trial name
- NCT06134713
- Testing
- cryotherapy with sterile saline at 2.5ºC, control with sterile saline at room temperature
- Where
- United Arab Emirates
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ajman University
Endodontic Disease, Root Canal Infection
3D Analysis of Root Canal Conformation
Aim To evaluate in vivo the shaping ability of the canal with 3 different single-file systems: Reciproc Blue, WaveOne Gold and XP Endo-Shaper, using cone beam computed tomography and 3D reconstructions to measure canal volume…
- Trial name
- NCT03680534
- Testing
- Root canal preparation
- Where
- Colombia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institucion Universitaria Colegios de Colombia
Endodontically Treated Teeth
Bite Force and Occlusal Force Distribution Following Root Canal Treatment.
Understanding the changes in bite force and occlusal force distribution in ETT is clinically important, as it can directly influence tooth prognosis, guide restorative treatment planning, and impact the long-term survival of the…
- Trial name
- B-FORCE RCT (NCT07626372)
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Effects of; Cold
Role of Cryotherapy in Reduction of Post Operative Endodontic Pain Following Single Visit Root Canal Therapy
AIM : To determine the efficacy of cold saline irrigation in reduction of post operative pain following root canal therapy. METHODOLOGY : Forty patients requiring root canal treatment on permanent single rooted teeth were…
- Trial name
- NCT03044470
- Testing
- cryotherapy
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mamata Dental College
Pulp Necrosis, Root Canal Infection
Comparison of Ultrasonic vs 980-nm Diode Laser Irrigant Activation for Reducing Residual Bacterial DNA in Necrotic Teeth
This randomized clinical trial aimed to compare residual oral bacterial DNA detection after ultrasonic irrigant activation and 980-nm diode laser irrigant activation during root canal treatment of necrotic single-rooted teeth.
- Trial name
- NCT07607028
- Testing
- Ultrasonic Activation, 980-nm Diode Laser Activation
- Where
- Indonesia
- Volunteers
- 16 people
- Sponsor
- Hasanuddin University
Endodontic Inflammation
Comparison Between the Vibringe and the Conventional Needle
The Vibringe is the first endodontic sonic irrigation system that enables delivery and activation of the irrigation solution in the root canal, in only one step.
- Trial name
- NCT03551587
- Testing
- Vibringe
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Inflammatory Pulp Diseases Related to Carious Teeth
Pulpotomy vs Pulpectomy Outcome.
Epidemiological data show a significant rate of failure of endodontic treatment of 20 to 50% worldwide, probably directly related to the difficulty of the procedure.
- Trial name
- PULPSAVE (NCT02727088)
- Testing
- Pulpotomy, Pulpectomy
- Where
- France
- Volunteers
- 226 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris