Clinical trials: Endodontic Inflammation
Pulpitis
A Clinical Trial Comparing FS With ZOE and Non-eugenol Based Materials in Primary Teeth Pulpotomies
Internal resorption in the most common cause of failure in FS pulpotomies in primary molars. This has been attributed to the release of free eugenol from the zinc and eugenol mixture of the base material over the pulp tissue.
- Trial name
- NCT05557812
- Testing
- non-eugenol based ZOE base material with Ferric Sulfate in primary molar pulpotomies, eugenol based zinc oxide and Ferric Sulfate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Acute Pulpitis
Postoperative Pain Associated With Three Endodontic Rotary Systems
Assessment of postoperative pain after root canal treatment using different rotary systems.
- Trial name
- NCT03065777
- Testing
- ONE ENDO, F6 SKYTaper, ProTaper Universal
- Where
- Egypt
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpotomy
Assessment of Pulpotomy Procedure Using NeoMTA Plus in Permanent Teeth With Carious Exposure
Many deep carious teeth are treated unnecessarily by root canal therapy, while with using current techniques and advances in compatible dental materials in addition to better understanding of biological response of the dental…
- Trial name
- PULPOTOMY (NCT03522051)
- Testing
- calcium silicate based material,
- Where
- Jordan
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Symptomatic Irreversible Pulpitis
Efficacy of Block Injection of an Anti Inflammatory Medicine in Patients With Mandibular Dental Pain
The aim of this study is to determine whether inferior alveolar nerve block of ketorolac and lidocaine would improve the success rate in teeth with symptomatic irreversible Pulpitis.
- Trial name
- IANB (NCT03410212)
- Testing
- Ketorolac Tromethamine
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Pulpitis - Irreversible
Comparison of a Prophylactic Intraligamentary Injection of Piroxicam Versus Mepecaine of Post-endodontic Pain
to evaluate the effect of a single intraligamentary injection of piroxicam on postoperative pain associated with endodontic procedures.
- Trial name
- NCT03006107
- Testing
- intraligamentary injection piroxicam, Intraligamentary mepevacaine
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries, Pulpitis - Reversible
Outcomes of the Hall Technique and Conventional Pulp Therapy for the Management of Caries in Primary Molars
Based on the changing understanding of carious biofilm development and caries progression, Sealing carious dentine beneath a restoration deprives the caries biofilm of nutrients and alters the environment sufficiently to slow or…
- Trial name
- NCT03885271
- Testing
- Hall Technique, Formecresol Pulpotomy
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Correlation Between Postoperative Pain and Apical Extrusion of Different Irrigation Activation Techniques
The aim of this clinical trial is : To evaluate effect of different techniques of irrigant activation: 1. LASER activation 2. sonic activation 3. ultrasonic activation 4. passive needle irrigation On: 1.
- Trial name
- NCT06573710
- Testing
- sonic activator, LASER activation, Ultrasonic activation
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Symptomatic Reversible Pulpitis (Disorder)
The Effect of Different Treatment Methods on the Apical Closure and Treatment Success in Permanent First Molars
The purpose of this thesis study is to evaluate the clinical and radiographic success of direct capping and pulpotomy applications using ProRoot MTA (mineral trioxide aggregate) in lower permanent first molars with reversible…
- Trial name
- NCT06575062
- Testing
- Direct Pulp Capping with ProRoot MTA, Pulpotomy with ProRoot MTA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Irreversible Pulpitis
Postoperative Pain After Pulpectomy in Primary Molars
To compare the post operative pain in pulpectomy of primary molars using a single rotary file system versus conventional manual instrumentation, through a Randomized Clinical Trial.
- Trial name
- NCT07427420
- Testing
- Fanta AF F one rotary files 20 taper 4, Manual files (k files ,Mani, Inc., Japan).
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain After Root Canal Therapy
Postoperative Pain Comparison of Two Root Canal Sealers in Irreversible Pulpitis
This study, approved by the Institutional Ethics Review Committee, AFID (Annex "A"), will involve 62 eligible patients from the Operative Dentistry Department, Armed Forces Institute of Dentistry.
- Trial name
- NCT06975761
- Testing
- Resin Based sealer, ZnO eugenol based sealers
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Pulpitis
Use of Tramadol Intraligamentary Injections
Introduction: To achieve painless treatment in patients with a failed primary IANB, supplementary anaesthesia has been advised. The majority of the studies evaluating intraligamentary injections have been performed on…
- Trial name
- NCT05538052
- Testing
- Tramadol hydrochloride, Lidocaine Hydrochloride
- Where
- India
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Symptomatic Irreversible Pulpitis
Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars
Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis.
- Trial name
- NCT03117491
- Testing
- GGNB injections, IANB injections, GGNB + IANB injections
- Where
- Iran
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Irreversible Pulpitis, Primary Teeth
Comparison of 3Mixtatin Pulpotomy and Metapex Pulpectomy in Primary Molars With Irreversible Pulpitis
The present study aims to evaluate the clinical and radiographic success of pulpotomy using 3Mixtatin versus pulpectomy using Metapex in primary molars with irreversible pulpitis in children aged 4 to 9 years.
- Conditions
- Irreversible Pulpitis, Primary Teeth, Pulp Disease, Dental
- Trial name
- NCT06925490
- Testing
- Metapex, 3Mixtatin
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
Effect of Premedication on Success of Inferior Alveolar Nerve Block Injection
The aim of this study is effect of premedication on success of inferior alveolar nerve block injection. Sixty healthy adult volunteers including criteria, are participating.
- Trial name
- NCT02601911
- Testing
- Ketorolac Tromethamine, Acetaminophen
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Endodontic Treatment, Irreversible Pulpitis
A Clinical Study: the Antibacterial Effect of Insoluble Antibacterial Nanoparticles (IABN) Incorporated in Dental Materials for Root Canal Treatment
The effect of Antibacterial Nanoparticles, Incorporated in root canal sealer material and in provisional restoration is going to be examined.
- Conditions
- Endodontic Treatment, Irreversible Pulpitis, Health Pulp, Infected Pulp
- Trial name
- IABN (NCT01167985)
- Testing
- IABN
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Root Canal Infection, Pain, Postoperative
Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment
The aim of this study is to evaluate the effect of low-level laser therapy (LLLT) and intracanal cryotherapy applications on postoperative pain in endodontic interventions of primary molar teeth with apical periodontitis.
- Conditions
- Root Canal Infection, Pain, Postoperative, Cryotherapy Effect, Laser
- Trial name
- NCT05476445
- Testing
- Control, Laser, Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Irreversible Pulpitis
Comparing the Outcome of Pulpotomy Using Biodentine and Portland Cement in Mature Cases With Irreversible Pulpitis: Randomized Clinical Trial
The aim of the study is to compare the treatment outcome of pulpotomy using Biodentine or Portland cement regarding success rate and post-operative pain.
- Trial name
- NCT04573374
- Testing
- Pulpotomy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Disease, Dental
Effect of Cavity Disinfectants on Post Operative Pain & Success of Partial Caries Removal
To investigate The Effect of Sodium hypochlorite and Chlorhexidine as cavity Disinfectants on the post operative pain and Success of Partial Caries Removal in deep carious lesion with moderate pulpitis in permanent teeth
- Trial name
- NCT06836882
- Testing
- Selective caries removal, Selective caries removal with NaOCl, Selective caries removal with CHX
- Where
- India
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pulpitis Reversible
Clinical, Radiographic and Patient Acceptance Evaluation of LASER Compared to Formocresol Pulpotomies inPrimary Molars
The goal of this clinical trial was to compare the clinical and radiographic success of laser versus formocresol pulpotomy in primary molars.
- Trial name
- NCT06200818
- Testing
- Diode laser, Er:CrYSGG, Formocresol
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pulpitis
Anesthetic Efficacy of 1,8mL and 3,6mL of Articaine in Inferior Alveolar Nerve Block in Irreversible Pulpitis
Ninety patients with irreversible pulpitis diagnostic will participate in this clinical study. The participants will be divided into 2 groups of 45 patients, who will receive the inferior alveolar nerve block injections of 1.8 mL…
- Trial name
- Volumes (NCT02422823)
- Testing
- Articaine, Epinephrine
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Isabel Peixoto Tortamano