Clinical trials: Endodontic Treatment
Periapical Periodontitis
Evaluation of Three Irrigants, Sodium Hypochlorite, Chlorhexidine and Combination of CHX+H2O2 in Endodontic Treatment.
This study will evaluate the synergistic effect of CHX + H2O2 when used as an irrigant during biomechanical preparation.in root canal treatment on periapical healing and compared with Chlorhexidine( CHX) and Sodium Hypochlorite…
- Trial name
- NCT04373018
- Testing
- Sodium hypochlorite, Chlorhexidine, Chlorhexidine + Hydrogen peroxide
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Pocket, Tooth,Non Vital
Chlorhexidine Intracanal Medicament in Periodontal Healing in Concomitant Endo Perio Lesion With Communication
The aim of this prospective randomized controlled clinical trial is to evaluate the effectiveness of chlorhexidine intracanal medicament along with periodontal treatment in concomitant endodontic periodontal lesions with…
- Trial name
- NCT02627326
- Testing
- open flap debridement
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Apical Periodontitis, Chronic Kidney Diseases
Effects of RCT on Periapical Healing, Inflammatory Markers, and Kidney Function Indicators in CKD Patients With AP
The purpose of this prospective study is to determine the effect of non-surgical root canal treatment in chronic kidney disease patients and healthy patients with apical periodontitis.
- Trial name
- NCT06446011
- Testing
- root canal treatment in Ckd patients, root canal treatment in healthy patients
- Where
- India
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Pain, Postoperative, Endodontically Treated Teeth
Post-Endodontic Instrumentation Pain After in a Single Session Associated With Photobiomodulation
The objective of this double-blind, randomized controlled clinical study will be to evaluate the effect f PBM on pain after endodontic instrumentation in the single-session treatment of upper molars and premolars.
- Trial name
- NCT06253767
- Testing
- Endodontic Treatment, Low Level Laser Therapy, Simulation Low Level Laser therapy
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Pulpitis
Celebrex Premedication in Teeth With Symptomatic Irreversible Pulpitis
Assessing the efficacy of Celebrex premedication on pain during and after endodontic treatment in teeth with symptomatic irreversible pulpits
- Trial name
- NCT03339544
- Testing
- Celebrex premedication
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain
Reduction of Post-endodontic Pain After RCT When Intracanal Cryotherapy is Used.
The goal of this research was to relate the occurrence of post-endodontic pain after single-visit RCT using Balanced Force technique and two reciprocating system when cryotherapy is used.
- Trial name
- PEP (NCT03448263)
- Testing
- Balanced Force technique, WaveOne technique, Reciproc technique
- Where
- Mexico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Endodontically Treated Teeth
Bite Force and Occlusal Force Distribution Following Root Canal Treatment.
Understanding the changes in bite force and occlusal force distribution in ETT is clinically important, as it can directly influence tooth prognosis, guide restorative treatment planning, and impact the long-term survival of the…
- Trial name
- B-FORCE RCT (NCT07626372)
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Pain
Comparative Evaluation of Post-endodontic Pain Using Two Rotary Instrumentation Systems
In this study the investigators aim to compare the post-operative pain using two single-file endodontic rotary systems : Reciproc and One shape.
- Trial name
- NCT02621034
- Testing
- Control, Reciproc, One shape
- Where
- Iran
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Zahedan University of Medical Sciences
Endodontic Disease, Regenerative Endodontics
Evaluation of Different Scaffolds in Regenerative Endodontic Treatment
The aim of this study is to evaluate and compare the regenerative potentials of Injectable Platelet-Rich Fibrin (I-PRF), Platelet-Rich Fibrin (PRF), and Blood Clot (BC) as different scaffolds regarding: Radiographic outcomes…
- Trial name
- NCT06945965
- Testing
- Injectable platelet-rich fibrin (i-PRF) scaffold, platelet-rich fibrin (PRF)scaffold, blood clot (BC) scaffold
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Regenerative Endodontics
Clinical and Radiographic Outcomes of PRF, Chitosan, and Blood Clot in Regenerative Endodontics of Molars
This clinical trial aimed to evaluate the long-term effects of using chitosan, blood clots, and platelet-rich fibrin as scaffolds in regenerative endodontics on tooth development.
- Trial name
- NCT07119619
- Testing
- Regenerative Endodontic Treatment Using a Blood Clot as a Scaffold, Regenerative Endodontic Treatment Using a Chitosan as a Scaffold, Regenerative Endodontic Treatment Using a Platelet Rich Fibrin as a Scaffold
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Inonu University
Root Canal Infection
The Influences of Root Canal Complexity and Clinician Training on Root Canal Treatment Outcomes.
This is an observational study that assess the impacts of (a) root canal treatment complexity and (b) clinical training on (1) root canal treatment success and (2) tooth survival, in a United Kingdom Armed Forces cohort.
- Trial name
- NCT05648305
- Testing
- Root Canal Treatment/ Re-treatment
- Volunteers
- 1,267 people, healthy volunteers welcome
- Sponsor
- Defence Primary Health Care, UK
Postoperative Pain After Endodontic Treatment
EFFECT OF NITI SYSTEMS AND XP-ENDO FINISHER ON POSTOPERATIVE PAIN
Title Evaluation of the Effect of Reciprocal and Rotational NiTi File Systems and XP-Endo Finisher Combination on Postoperative Pain Clinical Research Protocol Summary Objective The aim of this study is to compare the effects of…
- Trial name
- NCT07642596
- Testing
- Rotary NiTi file system, Rotary NiTi file system with irrigation activation device, Reciprocating NiTi file system
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- BUSRA OZTURK
Apical Periodontitis
Lesion Healing After Regenerative Endodontic Treatment
Endodontics involves various therapeutic interventions for diagnosing, preventing, and managing pulpal and periradicular pathologies.
- Trial name
- NCT06843850
- Testing
- regenerative endodontics
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Endodontically Treated Teeth, Post Operative Pain
Effect of Intra-Canal Cryotherapy on Postoperative Pain After Endodontic Procedures
The goal of this randomised clinical trial is to evaluate the effect of cryotherapy on postoperative pain after primary and secondary root canal treatment.
- Trial name
- NCT06134713
- Testing
- cryotherapy with sterile saline at 2.5ºC, control with sterile saline at room temperature
- Where
- United Arab Emirates
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ajman University
Symptomatic Irreversible Pulpitis (SIP)
Comparison Of Acetaminophen, NSAIDs, And Trypsin-Chymotrypsin Plus Acetaminophen For Post-Endodontic Pain After Single-Visit Root Canal Treatment
This randomized control trial will be planned according to PRIRATE 2020 guideline for reporting randomized trials in Endodontics.
- Trial name
- NCT07759349
- Testing
- Acetaminophen, NSAID, trypsin-chymotrypsin
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Post Operative Pain, Endodontic Treatment
Comparison of Post-operative Pain After Use of Endo-activator and Conventional Irrigation During Endodontic Treatment in Symptomatic Periapical Periodontitis
Introduction: The adequate removal of microorganisms, infected or necrotic pulp tissues and complete adequate seal of root canal system along with debridement is key to success of endodontic treatment.
- Conditions
- Post Operative Pain, Endodontic Treatment, Apical Periodontitis
- Trial name
- NCT06668662
- Testing
- Endoactivator, Conventional irrigation
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jinnah Sindh Medical University
Endodontically Treated Teeth
Evaluation the Post Operative Pain of Endodontic Treated Molar Tooth With Race and Reciprocal Systems Among Bandarabbas Patients in 2017
extrusion of infected dentin into the periapical tissue has been suggested as a major source of pain after endodontic treatment.
- Trial name
- NCT03488836
- Testing
- reciproc, race rotary
- Where
- Iran
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Sajad Ansari Fard
Endodontic Treatment of Primary Teeth
Mechanized Instrumentation for Endodontic Treatment of Primary Teeth
Mechanized instrumentation systems stand out amongst various devices used in modern Endodontics. Its use in Pediatric Dentistry, its action in primary teeth, has been in the center of many discussions and laboratory studies.
- Trial name
- NCT03453658
- Testing
- Manual instrumentation, Reciprocating Instrumentation
- Where
- Brazil
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Regenerative Endodontic, Apexification
Comparison of Apexification and Regenerative Endodontic Therapy: a Retrospective Study
In this study, the effects of mineral trioxide aggregation (MTA) apexification and regenerative endodontic treatment (RET) methods on periapical healing was compared with fractal analysis (FD) and periapical index (PAI).
- Conditions
- Regenerative Endodontic, Apexification, Fractals
- Trial name
- NCT05213026
- Testing
- Regenerative endodontics
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Periapical Periodontitis
Healing of Apical periodontitis-the Effect of Diabetes Mellitus and Tobacco Smoking
Apical periodontitis is an inflammatory process located around the apex of the root. It is mainly caused by a microbial infection of the pulp space.
- Trial name
- NCT04812171
- Testing
- non-surgical endodontic treatment
- Where
- Croatia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Romana Peršić Bukmir