Clinical trials: Endoleak
Abdominal Aortic Aneurysm
Contrast Enhanced Ultrasound Endoleak Identification and Classification
Surgery for abdominal aortic pathology usually occurs in the setting of advanced cardiovascular disease. The repair can be relatively simple or complex with multiple steps including open repair, placing a stent with a catheter…
- Trial name
- NCT04615559
- Testing
- Contrast enhanced ultrasound
- Where
- United States
- Sponsor
- University of Southern California
Abdominal Aortic Aneurysm
Evaluation of the Long Term Efficacy of Endovascular Treatment of Type 2 Endoleaks
Endovascular treatment has become the first choice to repair abdominal aortic aneurym, but exposes patients to a risk of endoleaks.
- Trial name
- NCT04409717
- Testing
- Type II endoleak treatment
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Aneurysm Abdominal
Reintervention Rates and Complications in Endovascular Aneurysm Repair (EVAR) and the Use of Colour Doppler Ultrasound (CDUS) and Computed Tomography Angiography (CTA) in Identifying Endoleak Complications
To provide a robust view of EVAR surveillance at UHL, this study proposes to retrospectively assess the surveillance programme to get a better view of post-operative complications following endovascular aneurysm repair.
- Trial name
- NCT07581392
- Where
- Ireland
- Volunteers
- 405 people
- Sponsor
- University Hospital of Limerick
Endoleaks
Evaluation of Contrast-Enhanced Ultrasound to Detect Endoleaks After Endovascular Aortic Aneurysm Repair
This study will be a cross-sectional survey of interobserver variability associated with contrast enhanced ultrasound (CEUS) to detect endoleaks using computed tomographic angiography (CTA) as the practice standard.
- Trial name
- AAA CEUS (NCT01005212)
- Testing
- Definity
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- E. Peden, MD
Aortic Aneurysm
Adjunctive Treatment With Doxycycline to Enhance the Durability of Endovascular Aortic Aneurysm Repair
The durability of endovascular aneurysm repair (EVAR) has been limited by development of endoleaks which may be secondary to progressive aortic degeneration by matrix metalloproteases (MMP).
- Trial name
- NCT00126204
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- The Foundation for Barnes-Jewish Hospital
Aortic Aneurysm Abdominal, Endovascular Aneurysm Repair (EVAR)
Abdominal Aortic Aneurysm Follow-up After Endovascular Repair by Non-invasive Vascular Elastography
Abdominal aortic aneurysm (AAA) is an abnormal dilatation of the aorta in the abdomen secondary to hypertension and atherosclerosis.
- Trial name
- AAA-Elasto (NCT01907386)
- Testing
- QSE-LSME - SSWI Ultrasound
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Endoleak, Aortic Aneurysm, Abdominal
CQDSA in Evaluation of Prognosis After EVAR
Re-hospitalization or re-intervention is sometimes necessary to treat type I and type III endoleaks after EVAR for its persistent increasing of pressure in aneurysm lumen.
- Trial name
- NCT02016131
- Where
- China
- Volunteers
- 49 people
- Sponsor
- Shanghai Zhongshan Hospital
Abdominal Aortic Aneurysm
Outcomes of FEVAR and BEVAR to Treat Secondary Type 1 Endoleak After EVAR: A Prospective Multicentre Study
Ten percent of the population above 60 years develops an aortic abdominal aneurysm. In case of rupture, this pathology leads to death in more than 70% of the cases.
- Trial name
- NCT04532450
- Testing
- Branched / fenestrated aortic stent graft
- Volunteers
- 85 people
- Sponsor
- University Paul Sabatier of Toulouse
Aortic Aneurysm, Endovascular Aortic Repair
Outcome of the Semibranch in Pararenal and Thoracoabdominal Aortic Pathologies. A Prospective, Multicentre Registry.
The goal of this registry is to evaluate the semibranch in branched endovascular aortic repair, which is a new tool in endovascular branched aortic repair.
- Conditions
- Aortic Aneurysm, Endovascular Aortic Repair, Stent-Graft Endoleak
- Trial name
- NCT06059053
- Testing
- Semibranch CMD branched aortic stentgraft
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Muenster
Aorta Aneurysm
Type 1 Endoleak : Fenestrated Custom Made Endograft (FEVAR) Versus Open Surgery Explantation (OSR) : What's the Best
Proximal type 1A endoleak is a worrying complication after endovascular repair of an abdominal aortic aneurysm (EVAR). The ideal solution is not obvious between relining by FEVAR and endograft explantation.
- Trial name
- NCT06187051
- Testing
- FEVAR, Explantation
- Volunteers
- 200 people
- Sponsor
- University Paul Sabatier of Toulouse
Abdominal Aortic Aneurysm
Abdominal Aortic Aneurysm Sac Healing and Prevention of Endoleaks - Netherlands
To determine the safety and efficacy of IMPEDE-FX Embolization Plug and/or IMPEDE-FX Rapid Fill to fill an abdominal aortic aneurysm (AAA) sac outside of an endovascular aneurysm repair (EVAR) stent graft.
- Trial name
- AAA-SHAPE_NLD (NCT04751578)
- Testing
- IMPEDE-FX Embolization Plug
- Where
- 3 sites in Netherlands
- Volunteers
- 15 people
- Sponsor
- Shape Memory Medical, Inc.
Post EVAR Endoleak Detection
Post EVAR Endoleak Detection : Model-based Iterative Reconstruction (MBIR) vs Adaptive Statistical Iterative Reconstruction (ASIR) CTA; a Prospective Study
The purpose of the study is to compare the accuracy of the diagnosis of endoleak in patient with EVAR comparing Adaptive statistical iterative reconstruction (ASIR) CTA and Model-based iterative reconstruction (MBIR- VEO TM).
- Trial name
- NCT02082834
- Testing
- abdominal MDCT examination
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Clermont-Ferrand
Abdominal Aortic Aneurysm
Abdominal Aortic Aneurysm Sac Healing and Prevention of Endoleaks
To determine the safety and efficacy of IMPEDE-FX Embolization Plug and/or IMPEDE-FX Rapid Fill to fill an abdominal aortic aneurysm (AAA) sac outside of an endovascular aneurysm repair (EVAR) stent graft.
- Trial name
- AAA-SHAPE (NCT04227054)
- Testing
- IMPEDE-FX Embolization Plug
- Where
- 2 sites in New Zealand
- Volunteers
- 15 people
- Sponsor
- Shape Memory Medical, Inc.
Aortic Aneurysm, Abdominal
Follow-up of Endovascular Aneurysm Treatment - The FEAT Trial
After endovascular abdominal aortic aneurysm repair, life-long follow-up is needed to monitor the effectiveness of exclusion of the aneurysm sac from blood flow.
- Trial name
- NCT00281411
- Testing
- Computed Tomography Angiography, Magnetic Resonance Angiography
- Where
- Netherlands
- Volunteers
- 46 people
- Sponsor
- Clinical Research Office Imaging Division
Morality, Hypothermic Circulatory Arrest Time
A Comparative Study of Different Hypothermic Circulatory Arrest Strategies on Aortic Surgery.
By comparing the clinical outcome of patients underwent different hypothermic circulatory arrest (mild hypothermic versus moderate hypothermic) during aortic arch surgery, this study aims to determine the optimal hypothermic…
- Conditions
- Morality, Hypothermic Circulatory Arrest Time, Aortic-cross Clamping Time, Cardiopulmonary Bypass Time
- Trial name
- NCT03454633
- Testing
- the temperature of hypothermic circulatory arrest
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xiaoping Fan. MD
Endovascular Abdominal Aortic Aneurysm Repair
Contrast Ultrasound in the Surveillance of Endovascular Abdominal Aortic Aneurysm Repair
The purpose of this study is to support the suspected expectation that Contrast enhanced Ultrasound (CUS) detects all endoleaks that have been detected by Computed Tomography (CT), and also find a number of leaks missed by CT.
- Trial name
- NCT01022892
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Varicocele, Endoleak
EASYX-1 : A Multicenter Study on Safety and Efficacy of Easyx Liquid Embolization Agent Used in Five Separate Indications
The EASYX™ Liquid Embolic is a new injectable, precipitating polymeric agent for the obliteration of vascular spaces through direct puncture or catheter access performed under X-ray guidance.
- Conditions
- Varicocele, Endoleak, Portal Vein Thrombosis, Bleeding
- Trial name
- EASYX-1 (NCT03477149)
- Testing
- Easyx
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abdominal Aortic Aneurysm, Juxtarenal Abdominal Aortic Aneurysm
Evaluation of Clinical Efficacy and Safety of Aortal Stent-Graft Created Using 3D Printing Technology
the comparison of physician-modified stent-graft created in 3D models versus custom-made devices in the treatment of complex abdominal aortic aneurysm
- Conditions
- Abdominal Aortic Aneurysm, Juxtarenal Abdominal Aortic Aneurysm, Pararenal Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
- Trial name
- NCT06969729
- Testing
- Physician-Modified Fenestrated Stent-Graft (3D-Printed Template-Guided)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Samodzielny Publiczny Szpital Kliniczny nr 2 PUM
Abdominal Aortic Aneurysm
Vasovist Endoleak Study
After endovascular treatment of an abdominal aortic aneurysm, lifelong imaging follow-up is needed to monitor the effectiveness of the treatment.
- Trial name
- NCT00483665
- Testing
- Computed tomography angiography, Magnetic resonance imaging
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- UMC Utrecht
Endograft Implantation to Repair Abdominal Aortic Aneurysm
Contrast Enhanced Ultrasound vs. Computed Tomographic Angiography in the Detection of Endoleaks Following AAA Repair
The purpose of the study is to compare two different types of imaging techniques to identify endoleaks. Following the endovascular procedure, subjects are seen at one month to have computed tomographic angiography (CTA) to…
- Trial name
- NCT01230684
- Testing
- Contrast Enhanced Ultrasound (Contrast Agent: OptisonTM)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan