Clinical trials: Endometrial
Infertility
Ulipristal Acetate on Progesterone Levels and Glycodelin-A Endometrial Pattern
Controlled ovarian stimulation (COS) for FIV increases progesterone (P) and estradiol (E2) serum levels in supraphysiologic concentrations at the end of follicular phase.
- Trial name
- NCT01391845
- Testing
- ulipristal acetate
- Where
- Argentina
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Programa de Asistencia Reproductiva de Rosario
Unexplained Infertility
Endometrial Injury in Women With Unexplained Infertility
Women between 18-39 years old who had been infertile (primary or secondary) for at least 1 year were recruited. In a parallel assignment eligible participants were randomized to receive either a single, site-specific endometrial…
- Trial name
- NCT02628756
- Testing
- Endometrial injury
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura Integrated Fertility Center
Endometrial Diseases
The Effect of Progressive Muscle Relaxation Exercise Applied Before Endometrial Biopsy on Pain, Anxiety Level and Patient Comfort in Premenopausal Women
This study was designed to determine the effect of progressive muscle relaxation exercises performed before endometrial biopsy on pain, anxiety levels, and patient comfort in premenopausal women.
- Trial name
- NCT07694037
- Testing
- progressive muscle relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Uskudar University
EMBRYO IMPLANTATION
Endometrial Scratch Effect on Pregnancy Rates in Patients Undergoing Egg-donation IVF
Clinical trial about the effect of endometrial scratch on pregnancy rates in patients undergoing a treatment with in-vitro fertilization with donor eggs, when doing the endometrial biopsy during the cycle prior to the embryo…
- Trial name
- NCT03108157
- Testing
- Endometrial scratch
- Where
- Spain
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Procreatec
Ectopic Pregnancy
The Correlation Between Uterine Endometrial Pattern and Ectopic Pregnancy
A prospective trail. Pregnant women in the first trimester with positive BHCG and no visualization of gestational sac will be recruited. The correlation between endometrial pattern and ectopic pregnancy will be assessed.
- Trial name
- NCT02963012
- Testing
- ultrasound examination
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Clinical Pregnancy
Immediate Versus Delayed Natural Cycle Frozen Embryo Transfers
Introduction: Based on recent studies the suggestion is that natural cycle frozen embryo transfers (NC FET) should preferably be used, with evidence suggesting that artificial cycle FET (AC FET) is subject to increased risks of…
- Trial name
- FET (NCT05215119)
- Testing
- natural cycle endometrial preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 818 people, healthy volunteers welcome
- Sponsor
- Antalya IVF
Endometrial Receptivity and Success Rate of IVF
Pilot Study on Molecular Quantitation and Sequencing of Endometrial Cytokines Gene Expression and Their Effect on the Outcome of In-vitro Fertilization (IVF) Cycle
Pilot study on molecular quantitation and sequencing of endometrial cytokines gene expression and their effect on the outcome of in-vitro fertilization (IVF) Cycle
- Trial name
- NCT01809509
- Testing
- Endometrial biopsy
- Where
- 2 sites in Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gynecologic Cancer, Ovarian Cancer
Gyn Onc Prehab Study
Patients will be randomized to a unimodal or trimodal prehabilitation program prior to surgery for known or suspected gynecologic cancer.
- Conditions
- Gynecologic Cancer, Ovarian Cancer, Endometrial Cancer, Cervical Cancer
- Trial name
- NCT04298827
- Testing
- Unimodal, Trimodal
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Endometrial Carcinoma, Malignant Uterine Neoplasm
Pelvic Floor Dysfunction and Quality of Life in Uterine Cancer Survivors
This trial studies pelvic floor dysfunction and quality of life in uterine cancer survivors. Using questionnaires may help researchers learn more about the sexual function and quality of life in uterine cancer survivors.
- Conditions
- Endometrial Carcinoma, Malignant Uterine Neoplasm, Uterine Corpus Cancer, Uterine Corpus Sarcoma
- Trial name
- NCT04634617
- Testing
- Questionnaire Administration
- Where
- United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Endometrial Receptivity Diagnosis
Quantitative Identification of Implantation Receptivity by Single Cell Transcriptome Analysis
This project aims to study the endometrial transcriptome at the single cell level in both endometrial native tissue (biopsies) and endometrial fluid.
- Trial name
- NCT03091023
- Testing
- Endometrial Biopsy and endometrial fluid collection
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Igenomix
Endometrial Cancer Stage I
Clinical Effects of Metformin on Fertility-sparing Treatment for Early Endometrial Cancer
The purpose of the study is to investigate the effects of metformin in addition to the conventional progestin therapy in the fertility-sparing treatment of early stage endometrial cancer.
- Trial name
- NCT04792749
- Testing
- Metformin
- Where
- South Korea
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Menstrual Cycle, Healthy
The Effects of Continuous Administration of a Monophasic Oral Contraceptive on Bleeding Days and Endometrial and Ovarian Function
The purpose of this study is to determine the safety and efficacy of a continuous combined oral contraceptive pill (CCOCP) regimen.
- Trial name
- NCT00128726
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Infertility
Use of Antagonist Versus Agonist GnRH in Oocyte Recipient Endometrium Preparation
Oocyte donation is a well established procedure in assisted reproduction treatments (ART). It is demonstrated that the use of hormonal substitution therapy, for the synchronization of the cycles between the recipients and the…
- Trial name
- NCT00633347
- Testing
- Antagonist GnRH Cetrotide, Agonist GnRH Acetate Triptoreline
- Where
- Spain
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Uterine Fibroids, Vaginal Bleeding
Optimal Order of Concurrent Office Hysteroscopy and Endometrial Biopsy
This study will look at the optimal order in which to perform concurrent office hysteroscopy and endometrial biopsy in female patients who present for evaluation of abnormal uterine bleeding at a fibroid and endometriosis…
- Trial name
- NCT02472184
- Testing
- Office hysteroscopy, Endometrial biopsy
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Endometrial Carcinoma, Cervix Carcinoma
GYNecological Cancers Treated with NETrin MAbs in Combination with Chemotherapy and /or Pembrolizumab
The aim of this study is to investigate the safety and the clinical activities of NP137 when combined with pembrolizumab and/or chemotherapies in patients with advanced/metastatic gynecological cancers (2 types: endometrial…
- Trial name
- GYNET (NCT04652076)
- Testing
- NP137, Pembrolizumab, Paclitaxel
- Where
- 15 sites in France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- NETRIS Pharma
Breast Cancer, Endometrial Cancer
Genistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal Women
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of genistein may be effective in preventing breast or endometrial cancer.
- Trial name
- NCT00099008
- Testing
- Genistein
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Luteal Phase Defect
Effects of Varied Estrogen Doses on Endometrial Receptivity
This study will help determine the effect of varied estradiol levels on the uterine lining in healthy humans that are not undergoing a stimulated in vitro fertilization (IVF) cycle.
- Trial name
- NCT02458404
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Inherited Cancer Syndrome, Prostate Cancer
Improving Care After Inherited Cancer Testing
The IMPACT Study seeks to refine and evaluate the effectiveness of interventions on improving guideline-adherent cancer risk management (CRM) and family communication (FC) of genetic test results for individuals with a documented…
- Conditions
- Inherited Cancer Syndrome, Prostate Cancer, Colorectal Cancer, Endometrial Cancer
- Trial name
- IMPACT (NCT04763915)
- Testing
- Correlative Studies (Survey), Correlative Studies (Interview), GeneSHARE
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Endometrial Cancer
Study of Insulin Resistance and Endometrial Cancer in Harris County, Texas
The goal of this clinical research study is to find out if there is a link between insulin resistance (or pre-diabetes) and endometrial cancer. Primary Objective: 1.
- Trial name
- NCT00495235
- Testing
- Questionnaire
- Where
- 8 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center