Clinical trials: Endometriomas
Endometrioma
Suture of the Ovary After Enucleation of Ovarian Endometrioma
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of ectopic endometrial-like tissue outside the uterine cavity.
- Trial name
- SOAVE-1 (NCT03788720)
- Testing
- Suture of the ovarian cortex, No suture of the ovarian cortex
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Endometriosis, Endometriosis Ovary
EHP-5 in Preoperative Assessment in Women With Endometriosis
There is no validated tool in quality-of-life assessment of women with endometriosis in Croatia. First aim is to validate Endometriosis Health Profile-5 (EHP-5) before implementing this questionnaire in clinical practice.
- Conditions
- Endometriosis, Endometriosis Ovary, Endometriosis-related Pain, Quality of Life
- Trial name
- EHP-5CRO (NCT04491305)
- Testing
- Surgically treated women with endometriosis and confirmed diagnosis
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University of Zagreb
Endometrioma
Endometrioma Treatment and Ovarian Function
Ovarian endometriosis (endometrioma) can be a cause of subfertility. According to European Society of Human Reproduction and Embryology (ESHRE) guidelines, surgery for endometrioma is recommended when an endometrioma is more than…
- Trial name
- EnTOF (NCT04452123)
- Testing
- Laparoscopic argon plasma treatment of endometrioma, Laparoscopic stripping of endometrioma and suture/coagulation of the rest of ovary
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Charles University, Czech Republic
Unilateral Ovarian Endometrioma
Vasopressin Injection Technique to Preserve Ovarian Reserve in Surgery for Unilateral Ovarian Endometriomas
Endometriosis is a common disease with an incidence rate of 15% in women of childbearing age, and is a chronic disease that significantly affects women's quality of life by causing two problems: pain and infertility.
- Trial name
- NCT04372836
- Testing
- Vasopressin injection
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Yonsei University
Endometrioma, Inflammation
Anti-inflammatory Markers in Endometrioma
Investigators aimed to measure the serum levels of adropin, salusin-α, netrin-1, and nesfatin-1, anti-inflammatory effects of which have been demonstrated previously, in endometriosis patients and to find out any association of…
- Trial name
- NCT04371133
- Testing
- Adropin (ng/L)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Endometrioma
Comparison of Laparoscopic Endometrioma Stripping Versus Ethanol Sclerotherapy( CLESS)
The aim of this study is to compare two different laparoscopic surgical techniques (endometrioma stripping vs ethanol sclerotherapy) in terms of ovarian reserve (AMH levels), recurrence rate and pain relief.
- Trial name
- CLESS (NCT04178876)
- Testing
- ethanol sclerotherapy, stripping technique
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Catholic University of the Sacred Heart
Ovarian Reserve, Endometrioma
Endometrioma Per se Versus Treatment Related Reduction in Ovarian Reserve (ERROR-2 Trial)
The present multi-center study aimed to evaluate whether endometrioma-associated decline in ovarian reserve is progressive in the absence of an intervention and is greater in magnitude than the natural decline over time.
- Trial name
- ERROR2 (NCT03620838)
- Testing
- oral contraceptive pill, oral progesterone
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Uludag University
Ovarian Reserve, Endometrioma, PTEN-AKT-FOXO3 Gene Expression
PTEN-AKT-FOXO3 Gene Expression Relation With Low-ovarian Reserve in Endometriomas
In this study, we aimed to investigate the relationship between PTEN-AKT-FOXO3 gene expression and decrease in ovarian reserve in the presence of endometrioma and other benign ovarian pathologies.
- Trial name
- NCT04058912
- Testing
- PTEN-AKT-FOXO3 Gene Expression
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uludag University
Endometriosis, Endometrioma
Raman Spectroscopy and Endometriosis
We aimed to use Raman spectroscopy to detect differences between healthy controls and patients with surgically proven endometriosis.
- Trial name
- NCT04015297
- Testing
- raman analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Endometriosis, Endometrioma
Genomic Maps of Endometrial Tissues of Patients With Endometriosis and Healthy Controls
Endometriosis is a chronic inflammatory disease that affects 10-17% of women in childbearing age, 35-60% of women with chronic pelvic pain and can cause infertility, costing as much as 2.8 billion dollars per year.
- Trial name
- NCT03687398
- Testing
- genetic testing with nanoclonal technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Endometrioma
Surgicel Reduces Ovarian Endometriomas Recurrence
Two hundred women aged from 20 to 35 years undergoing conservative laparoscopic treatment of ovarian endometriomas (either by drainage or cyst wall excision) were included.
- Trial name
- NCT02947724
- Testing
- SURGICEL®
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ovarian Endometrioma
Laparoscopic Ovarian Cystectomy Versus Aspiration and Coagulation in Ovarian Endometrioma
The aim of this study is to evaluate the impact of laparoscopic ovarian cystectomy versus aspiration and coagulation on ovarian reserve and pelvic pain in cases of ovarian endometrioma.
- Trial name
- NCT03615352
- Testing
- ovarian cystectomy, ovarian cyst aspiration and coagulation
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Shaimaa Mostafa Mohammed Refaay El shemy
Ovarian Endometrioma
Trans-vaginal Aspiration of Small Ovarian Endometrioma. Comparison of Two Different Techniques Before ICSI
women candidate for ICSI and having ovarian endometrioma smaller than 5 cm will be randomized to either transvaginal aspiration alone or transvaginal aspiration follwed by injection of small parts of oxidized regenerated…
- Trial name
- NCT03784404
- Testing
- Transvaginal aspiration, transvaginal aspiration and surgicel injection, Intracytoplasmic sperm injection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Endometrioma
Effect of Prolonged GnRh Agonists on Results of Intracytoplasmic Sperm Injection (ICSI ) in Endometrioma Patients
Investigators compare ICSI results for endometrioma patients with or without cyst aspiration if more than 5cm \&with or without GnRh agonists for all endometrioma patients
- Trial name
- GnRh (NCT02737800)
- Testing
- endometrioma aspiration, GnRh agonist ( Decapeptyl ), standard long stimulation protocol
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Kasr El Aini Hospital
Ovarian Endometrioma, Ovary Cyst
The Impact of Electrocoagulation on Ovarian Reserve After Laparoscopic Excision of Ovarian Cysts.
The aim of the study is to evaluate the effect of bipolar electrocoagulation on ovarian reserve.
- Trial name
- NCT03585309
- Testing
- The impact of electrocoagulation on ovarian reserve after laparoscopic excision of ovarian cysts:
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Ain Shams University
Endometriomas
Antimullerian Hormone in Endometriomas
The purpose of this multicenter study is to evaluate the ovarian reserve after alcohol sclerotherapy of endometriomas versus conventional surgery.
- Trial name
- NCT02669628
- Testing
- Surgical technique, Alcohol sclerotherapy
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Hospital Universitari de Bellvitge
Endometrioma
The Impact on Ovarian Reserve of Ovarian Cystectomy Versus Laser Vaporization in the Treatment of Ovarian Endometrioma: a Randomized Clinical Trial
This is a prospective, multicentric (two centers: 1:San Raffaele Scientific institute, Milan, Italy; 2:Jagiellonian University, Collegium Medicum, Cracow, Poland), randomized (1:1) clinical trial that includes patients undergoing…
- Trial name
- Laser (NCT03227640)
- Testing
- stripping technique, CO2 laser (AcuPulse Duo, Lumenis)
- Where
- 2 sites in Italy, Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Ovarian Endometrioma
Impact on Ovarian Reserve of Diode Laser vs Bipolar Coagulation of Endometriomas
Endometriosis is a benign chronic gynaecological disease that affects 10% of women of reproductive age and takes 40% of them to assisted reproduction techniques.
- Trial name
- NCT02350452
- Testing
- Diode laser coagulation, Bipolar coagulation
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Endometrioma, Endometriosis
Efficacy of Aspiration and Sclerotherapy During Laparoscopy Using 95% Ethanol for the Treatment of Endometriomas
The purpose of this study is to evaluate the efficacy of aspiration and sclerotherapy during laparoscopy using 95% ethanol for the treatment of endometriomas, compared to the standard cystectomy treatment - a prospective case…
- Trial name
- EASLETE (NCT02472873)
- Testing
- Aspiration and Sclerotherapy of endometriomas., cystectomy of endometriomas., Ethanol
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Meir Medical Center
Endometrioma
Laparoscopic Ovarian Cystectomy of Endometrioma vs Deroofing and Ovarian Reserve
The purpose of this study is to evaluate the impact of laparoscopic ovarian cystectomy versus laparoscopic cyst deroofing on ovarian reserve measured by serum levels of anti mullerian hormone and antral follicle count in patients…
- Trial name
- NCT01808170
- Testing
- Laparoscopic ovarian cystectomy, laparoscopic cyst deroofing
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Ain Shams University