Clinical trials: Endometriomas, open to volunteers
Endometriosis
Study on the Ultrasound and Biological Characteristics of Atypical Endometriosis.
This study hypothesizes that the histological, immunophenotypic, and molecular characterization of atypical endometriotic lesions may be related to specific clinical and ultrasound features.Identifying potentially atypical…
- Trial name
- ENDOAT (NCT07816133)
- Testing
- Retrospective case-control analysis, prospective case-control group
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Endometrioma, Endometriosis Ovary
The Therapy of Large Endometrioma
Endometrioma's prevalence is between 23 and 55%. It causes pelvic pain, decrease fertility and ovarian reserve. Currently, there's no recommendation about large endometrioma's treatment and there's no information on the best…
- Trial name
- ENDOKYSTE (NCT04704115)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Lille
Benign Ovarian Cyst
Comparison of Hemostatic Agent to Suture in Terms of Hemostatic Function and Preservation of Ovarian Function
This study aims to evaluate the efficacy of preservation of ovarian function, hemostasis, and safety of a hemostatic agent versus suturing during laparoscopic ovarian cystectomy for ovarian endometriosis.
- Trial name
- PRAHA-2 (NCT04643106)
- Testing
- Hemostatic agent (EVICEL®) application during laparoscopic ovarian cystectomy, suturing with barbed sutures during laparoscopic ovarian cystectomy
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Infertile Women Undergoing IVF or ICSI
Benefit of Ethanol Sclerotherapy of Endometriomas Before Ovarian Stimulation on Pregnancy Rates in IVF/ICSI
Evaluation of progressive pregnancy rates (with an embryo with cardiac activity at 12 weeks), on a first attempt at IVF/ICSI (fresh and frozen embryo transfers) following the discovery of one or two endometrioma(s) of 30 to 80…
- Trial name
- SCLERENDO (NCT06878053)
- Testing
- ethanol sclerotherapy
- Volunteers
- 174 people
- Sponsor
- Poissy-Saint Germain Hospital
Ovarian Endometrioma, Endometriosis
Histological Assessment of Tissue Penetration Depth of Argon Beam Coagulation in Ovarian Endometriomas
The goal of this clinical trial is to evaluate the depth of tissue penetration of Argon Beam Coagulation (ABC) during laparoscopic surgery for ovarian endometriomas.
- Trial name
- ENDO-ARGON (NCT07711743)
- Testing
- Argon Plasma Coagulation
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ovarian Endometrioma, Endometrioma
Estetrol/Drospirenone to Reduce the Average Size of Endometriomas
Endometriosis, a chronic gynecological disorder associated with pain and infertility, is a common condition affecting approximately one in ten women.
- Trial name
- ERASE (NCT05837624)
- Testing
- Estetrol/Drospirenone
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Andrew Zakhari
Ovarian Endometrioma, Infertility, Female
Surgery and ART For Endometrioma
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of endometrial-like tissue, glands and stroma outside the uterine cavity.
- Trial name
- NCT03717870
- Testing
- Laparoscopic enucleation of ovarian endometrioma., Prolonged pituitary downregulation, Assisted Reproductive Technology (ART)
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
IVF, Endometrioma
Endometrioma Ethanol Sclerotherapy - Prospective Cohort Study Protocol
Ovarian endometriomas are cystic masses lined with endometrial tissue that contains fluid arising from a collection of menstrual debris.
- Trial name
- NCT06971458
- Testing
- Sclerotherapy
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Hillel Yaffe Medical Center
Endometriosis, Endometrioma
Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)
The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy
- Trial name
- NCT06847685
- Where
- 3 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Ovarian Endometrioma
Non-inferiority Trial Comparing Vaginal Ultrasound-guided Ethanol Sclerotherapy and Laparoscopic Cystectomy for the Management of Ovarian Endometriomas (E-STEP)
Endometriosis is a disease that affects between 6 and 10% of women of childbearing age. It is defined by the presence of endometrial tissue outside the uterine cavity, most often in the ovaries or the peritoneal cavity.
- Trial name
- E-STEP (NCT07004959)
- Testing
- Vaginal ultrasound-guided ethanol sclerotherapy, Laparoscopic cystectomy
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Endometriosis Ovary, Endometrioma
Conservative Endometrioma Surgery
To study which surgical technique offers better results in treating endometriomas in terms of ovarian reserve preservation. The 2 conservatives techniques used are: 1. The combined technique 2.
- Trial name
- BLAST (NCT04151433)
- Testing
- Comparison between 2 different laparoscopic techniques in conservative surgical treatment of endometriomas (both arms are existing and accepted surgical strategies).
- Where
- 4 sites in Belgium
- Volunteers
- 92 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Endometrioma
Suture of the Ovary After Enucleation of Ovarian Endometrioma
Endometriosis is an estrogen-dependent chronic disease, characterized by the presence of ectopic endometrial-like tissue outside the uterine cavity.
- Trial name
- SOAVE-1 (NCT03788720)
- Testing
- Suture of the ovarian cortex, No suture of the ovarian cortex
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Ovarian Endometrioma
Assessment of Ovarian Reserve in the Treatment of Ovarian Endometrioma With Cystectomy or Argon Plasma Coagulation: A Aandomized Clinical Trial
Endometriosis is a benign, chronic, and often recurrent gynecological disease affecting approximately 10% of women of reproductive age.
- Trial name
- NCT07666412
- Testing
- Argon Plasma Coagulation (APC) ablation
- Where
- Italy
- Volunteers
- 146 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Endometriosis
Guangdong Provincial Endometriosis Clinical Research Cohort
Endometriosis is a chronic condition that may cause pelvic pain, ovarian cysts, infertility, and recurrent symptoms. This prospective observational cohort study will enroll women aged 18 to 45 years with endometriosis and age…
- Trial name
- NCT07749053
- Where
- China
- Volunteers
- 716 people, healthy volunteers welcome
- Sponsor
- Li Li
Endometriotic Cyst of Ovary
Letrozole in Preventing Recurrence of Endometrioma Following Laparoscopic Ovarian Cystectomy
Endometriosis is a chronic inflammatory disease that affects approximately 10-15% of women of reproductive age. Symptoms include dysmenorrhoea, chronic pelvic pain, dyspareunia and infertility.
- Trial name
- NCT05487092
- Testing
- Letrozole
- Where
- 5 sites in Hong Kong
- Volunteers
- 194 people
- Sponsor
- The University of Hong Kong
Endometrioma
Endometrioma Sclerotherapy and Ovarian Preservation
A randomised controlled trial assessing ovarian reserve after laparoscopic ethanol sclerotherapy of ovarian endometrioma compared to standard treatment of surgical excision of endometrioma.
- Trial name
- ENDOSAVE (NCT06775769)
- Testing
- Sclerotherapy, Routine Care
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Endometriosis, Endometrioma
PET/MRI for Evaluation of Endometriosis
This study aims to determine if PET/MRI can detect endometriosis and potentially improve upon currently available non-invasive diagnostic capabilities.
- Trial name
- NCT06377553
- Testing
- Radiotracer Injection, Imaging, Rectal Ultrasound Gel Injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Ovarian Endometrioma, Endometriosis
Selective Removal of Endometriotic Lesions Using CUSA Clarity in Ovarian Endometriomas
This study aims to evaluate the feasibility and tissue selectivity of a novel surgical technology, the Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity, in the management of ovarian endometriomas.
- Trial name
- CUSA-ENDO (NCT07215130)
- Testing
- Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Kanazawa University
Endometrioma, Fertility
Ablative Technique For Ovarian Preservation In Endometrioma
The goal of this clinical trial is to compare pregnancy rates after different surgical treatments for endometriomas in adult women who have one or more ovarian cysts (endometriomas) larger than 2 cm requiring surgery.
- Trial name
- ATOPE (NCT07119060)
- Testing
- Cystectomy, plasma vaporization, Sclerotherapy
- Where
- France
- Volunteers
- 332 people
- Sponsor
- Clinique Tivoli Ducos
Endometriosis
Argon Plasma Treatment for Ovarian Endometrioma Compared to Standard Cystectomy
The study is a prospective, monocentric, randomized controlled, two-armed, pilot-study conducted at Department for Women's Health, Tuebingen, Germany.
- Trial name
- OVAPLAS (NCT07065214)
- Testing
- APC, Lap bipolar forceps
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Erbe Elektromedizin GmbH