Clinical trials: Endometriosis
Deep Endometriosis
Radiological Diagnostics in Patients With Deep Endometriosis
Endometriosis is a benign, chronic, recurrent disease characterised by the presence of endometrial glands and stroma outside the uterine cavity.
- Trial name
- NCT06799767
- Where
- Italy
- Volunteers
- 94 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Endometriosis, Ovarian
Edessy Stem Cell Score (ESS), Endometrium, Endometrioma
Purpose of this study is to evaluate stem cell expression (SCE) in endometriotic (E) and non endometriotic ovarian and endometrial tissues.
- Trial name
- NCT02103452
- Testing
- Ovarian and endometrial samples
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Endometriosis
Efficacy and Safety of SH T00660AA in Treatment of Endometriosis
The purpose of this study is to demonstrate safety and efficacy of SH T00660AA compared to placebo in the treatment of endometriosis
- Trial name
- NCT00225199
- Testing
- Visanne (BAY86-5258, SH T00660AA)
- Volunteers
- 198 people
- Sponsor
- Bayer
Endometriosis
Does Immunotherapy Have a Role in the Management of Endometriosis?
Pathological specimens of 40 women that had been operated for endometriosis will be included in this study. These tissues will be stained with a marker named as PDL-1 in pathological examination.
- Trial name
- NCT03464799
- Testing
- immunohistochemical staining
- Volunteers
- 40 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Endometriosis, Pelvic Pain
Endometriosis : Traditional Medicine vs Hormone Therapy
This 36-week study will determine whether traditional Chinese medicine (acupuncture and Chinese herbs) is as effective as hormone therapy for alleviating endometriosis-related pelvic pain.
- Trial name
- NCT00034047
- Testing
- Acupuncture, Chinese Products, Nafarelin
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Endometriosis (Diagnosis), Endometriosis
Combining Ultrasound and Biomarkers to Diagnose Superficial Endometriosis
Endometriosis is a benign gynecological disease characterized by uterine-like cells growing outside the uterus, leading to pain, infertility, and inflammation.
- Trial name
- SPGENDO (NCT05523284)
- Testing
- SonoPODography
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Endometriosis
Non-Interventional Study of Zoladex in Endometriosis
This is a prospective, open label NIS, which is to assess the efficacy of Zoladex in adjuvant setting after operation in moderate to severe endometriosis patients.
- Trial name
- NCT00938496
- Where
- 11 sites in China
- Volunteers
- 408 people
- Sponsor
- AstraZeneca
Endometriosis
Whole-Body Cryotherapy as a Non-Pharmacological Treatment to Reduce Chronic Pelvic Pain and Improve Quality of Life in People With Endometriosis
The aim of this study is to investigate whether whole-body cryotherapy (a brief exposure to very cold temperatures) can help reduce pain and improve quality of life in people living with endometriosis, and whether it may…
- Trial name
- CHILL-Endo (NCT07603960)
- Testing
- Whole-Body Cryotherapy
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
Endometriosis
ENDS (ENDometriosis & FuSobacterium) Unveiling the Contribution of Fusobacterium Infection to the Development of Endometriosis
This will be a clinical interventional longitudinal study, without pharmacological intervention/device evaluation. A control group would however be recruited for secondary objective 1 and 2.
- Trial name
- ENDS (NCT06368596)
- Testing
- Fusobacterium detection
- Where
- Italy
- Volunteers
- 845 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Prolapse; Female, Endometriosis-related Pain
Functional Links Between the Temporomandibular Joint and the Pelvis in Gynecology
1 Recruitment. 2. Collection of written consents for the study. 3. Random assignment to groups with and without intervention. 4.
- Trial name
- TMJ and Pelvis (NCT05978414)
- Testing
- Visceral therapy
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Poznan University of Physical Education
Endometriosis, Endometriosis-related Pain
Microbiota and Immunoassay in Women With and Without Endometriosis: a Pilot Study
Endometriosis is an estrogen-dependent chronic inflammatory disease characterized by the presence of endometrial tissue outside the uterine cavity. This pathology has a prevalence of about 5-10% in reproductive-aged women.
- Trial name
- NCT05433909
- Testing
- Blood, fecal, vaginal and endometrial liquid samples
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Endometriosis, Infertility
GnRH-a and Pregnancy Rate in In Vitro Fertilization (IVF) Cycles.
The investigators attempted to establish a rationale for the Gonadotropin Releasing Hormone-agonist (GnRH-a) administration, post-laparoscopically, in women with mild endometriosis (until stage II, according to AFS) who underwent…
- Trial name
- NCT01269125
- Testing
- Leuprolide, IVF
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- University of Ioannina
Endometriosis
Endometriosis: Sexual Dysfunction and Adaptation Strategies Among Couples
The primary objective of this study is to evaluate the presence/absence and description of persistent sexual troubles following surgical treatment for endometriosis for women, and their partners.
- Trial name
- DYSEXTRIOSE (NCT01402791)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Endometriosis Rectum
Association Between Ultrasound Morphology of Intestinal Endometriosis Nodules and Symptom Severity
Association between the ultrasound appearance of deep bowel endometriosis and the frequency of pain
- Trial name
- NCT06720688
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Endometriosis
Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups
The goal of this clinical trial is to learn if a wearable brain stimulation device called NettleEndo can reduce chronic pelvic pain and improve wellbeing in women with endometriosis.
- Trial name
- RELIEF (NCT06974773)
- Testing
- NettleEndo
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Samphire Group, Inc.
Endometriosis, Surgery
Physical Therapy After Endometriosis Excision
This is a randomized controlled pilot study comparing a home pelvic floor physical therapy program to routine post-operative care for patients undergoing endometriosis excisional surgery without hysterectomy.
- Trial name
- NCT07127783
- Testing
- Active Recovery, Standard Postoperative Instructions
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Endometriosis
Combined Effect of Therapeutic Ultrasound and Trans Cutaneous Electrical Nerve Stimulation on Endometriosis
This study will be conducted to investigate the combined effect of therapeutic ultrasound and transcutaneous electrical nerve stimulation (TENS) on relieving adhesions and pain related to endometriosis.
- Trial name
- NCT06537765
- Testing
- Medical treatment, Therapeutic ultrasound (US), Transcutaneous electrical nerve stimulation (TENS)
- Volunteers
- 45 people
- Sponsor
- Cairo University
Endometriosis
PGL5001 Proof of Concept Study in Inflammatory Endometriosis
This is a prospective, three-part (Part A1, Part A2 and Part B),Phase II study investigating the efficacy, safety, pharmacokinetics and pharmacodynamics of the JNK inhibitor PGL5001 orally administered for up to 5 months with…
- Trial name
- JADE (NCT01630252)
- Testing
- PGL5001
- Where
- Poland
- Volunteers
- 24 people
- Sponsor
- PregLem SA
Endometriosis, Unexplained Infertility
Elagolix for Fertility Enhancement Clinical Trial
Studies suggest that undiagnosed endometriosis results in poor reproductive outcomes in the setting of In Vitro Fertilization and Embryo Transfer (IVF-ET).
- Trial name
- EFFECT (NCT04039204)
- Testing
- Elagolix, Ortho Cyclen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Chinese Medicine, Stable Coronary Heart Disease
Xuefu-Zhuyu Capsule for the Treatment of "Qizhi Xueyu Zheng" (Qi Stagnation and Blood Stasis Syndrome)
"Xuefu-Zhuyu capsule" (XFZY) is made from a classic Fangji "Xuefu-Zhuyu Decoction" in an ancient Chinese medical book "Yi Lin Gai Cuo" by Chinese physician Wang Qingren, which is the most representative formula for the treatment…
- Conditions
- Chinese Medicine, Stable Coronary Heart Disease, Chronic Insomnia, Headache
- Trial name
- NCT04218487
- Testing
- Xuefu-Zhuyu Capsule, conventional therapy
- Where
- 12 sites in China
- Volunteers
- 720 people
- Sponsor
- Zhong Wang