Clinical trials: Endometriosis
Endometriosis
A Study to Evaluate the Safety and Efficacy of BOL-DP-o-08 in Patients With Endometriosis Syndrome.
A Phase 2a, Single-center, randomized, double-blind, placebo-controlled study, in 80 subjects diagnosed with Endometriosis, stage 2-4
- Trial name
- NCT04174911
- Testing
- BOL-DP-o-08
- Sponsor
- Breath of Life International Pharma Ltd
Patient With a Prescribed Endotest, Endometriosis (Diagnosis)
Impact of Endotest on Patients' Quality of Life: a Cohort Study
Ziwig Endotest® ('Endotest') is marketed in several countries, including Switzerland, which was the first country to make it available in 2022.
- Trial name
- ENDOLIFE (NCT07560852)
- Testing
- Questionnaire
- Where
- 7 sites in France
- Volunteers
- 20,000 people
- Sponsor
- ZIWIG
Endometriosis
A Multinational, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Investigate the Efficacy, Safety and Duration of Effect of a Single Administration of Various Doses of Cetrorelix SR in Subjects With Histologically Confirmed Endometriosis
Identify effective doses of cetrorelix SR in the treatment of symptoms of endometriosis, describe dose effect relationship and duration of symptom relief
- Trial name
- NCT00244452
- Testing
- Cetrorelix
- Where
- 57 sites in Australia, Belgium and 6 more
- Sponsor
- Solvay Pharmaceuticals
Endometriosis (Diagnosis)
Impact of Food Supplementation on Quality of Life in Patients With Endometriosis and Pelvic Pain.
This study examines whether the food supplement Doliral can improve quality of life and reduce pelvic pain in women with endometriosis, compared with placebo, over several weeks.
- Trial name
- ENDOLIRAL (NCT07393958)
- Testing
- Food supplement (T1675)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Arafarma Group, S.A.
Endometriosis, Uterine Fibrioids
A Study to Evaluate Pregnancy Outcomes in Females Treated With Oral Elagolix Tablets and Capsules
Orilissa is a drug approved for the management of moderate to severe pain associated with endometriosis. Oriahnn is approved for heavy menstrual bleeding due to uterine fibroids.
- Trial name
- NCT04464187
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- AbbVie
Deep Infiltrating Endometriosis (DIE)
A Study to Describe the Efficacy of Diphereline Following Conservative Surgery in Deep Infiltrating Endometriosis (DIE) Patients Over a Period of 24 Months
The purpose of this study is to describe changes in the intensity of specific endometriosis symptoms from baseline pre-surgery to after surgery and subsequent continuous Diphereline (Triptorelin Acetate) treatment for up to 24…
- Trial name
- DIE-NIS (NCT01942369)
- Testing
- Triptorelin Acetate 3.75mg intramuscular injection
- Where
- 18 sites in China
- Volunteers
- 402 people
- Sponsor
- Ipsen
Contraception
Study of the Safety and Contraceptive Efficacy of Relugolix Combination Therapy in Women With Uterine Fibroids or Endometriosis Who Are at Risk for Pregnancy
The purpose of this study is to assess the contraceptive efficacy of relugolix combination therapy.
- Trial name
- SERENE (NCT04756037)
- Testing
- Relugolix Combination Therapy
- Where
- 112 sites in United States, Puerto Rico
- Volunteers
- 1,164 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
Endometriosis
Late Phase II Clinical Study of KLH-2109 in Patients With Endometriosis
The purpose of this study is to evaluate the efficacy, safety, and dose-response relationship of KLH-2109 compared to placebo in Japanese patients with endometriosis.
- Trial name
- NCT02778919
- Testing
- KLH-2109, Leuprorelin acetate
- Where
- Japan
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Endometrial Related Pain
Safety and Efficacy Study of MT-2990 in Women With Endometriosis
The purpose of this study is to assess the safety and efficacy of MT-2990 for treatment of moderate to severe endometriosis-related pain in women with surgically diagnosed endometriosis.
- Trial name
- NCT03840993
- Testing
- MT-2990
- Where
- 51 sites in United States
- Volunteers
- 76 people
- Sponsor
- Tanabe Pharma America, Inc.
Endometriosis
Safety and Efficacy of SH T00660AA in Treatment of Endometriosis
The purpose of this study is to demonstrate safety and efficacy of SH T00660AA for the treatment of endometriosis
- Trial name
- NCT00225186
- Testing
- Visanne (SH T00660AA , BAY86-5258)
- Where
- 28 sites in Germany, Italy and 1 more
- Volunteers
- 168 people
- Sponsor
- Bayer
Endometriosis, Pain
Efficacy and Safety Study of Elagolix in Women With Endometriosis
The purpose of this study is to evaluate elagolix (NBI-56418) compared to placebo for its effects on endometriosis related pelvic pain and its safety.
- Trial name
- NCT00973973
- Testing
- Elagolix
- Volunteers
- 137 people
- Sponsor
- AbbVie
Severe and Recurrent Endometriosis
Letrozole in the Treatment of Severe and Recurrent Endometriosis
Endometriosis is a condition in which abnormal growth of tissue histologically resembling the lining of the uterus (endometrium) is present outside of the uterus.
- Trial name
- NCT00240942
- Testing
- Letrozole
- Volunteers
- 40 people
- Sponsor
- Novartis Pharmaceuticals
Abnormal Uterine Bleeding, Endometriosis
Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy
The aim of this study is to show the superiority of the new unidirectional barbed suture (SYMMCORA® mid-term, unidirectional) to conventional suture material in terms of time to perform the vaginal cuff closure during gynecologic…
- Conditions
- Abnormal Uterine Bleeding, Endometriosis, Uterine Prolapse, Uterine Cancer
- Trial name
- BARHYSTER (NCT06024109)
- Testing
- Closure of the Vaginal Cuff after Total Hysterectomy
- Where
- 2 sites in Germany, Spain
- Volunteers
- 132 people
- Sponsor
- Aesculap AG
Endometriosis
To Evaluate Effectiveness of Visanne in Improving Quality of Life in Asian Women With Endometriosis
This study is a prospective observational cohort study. The study will be conducted in routine clinical practice settings. It is planned to enroll 870 patients with endometriosis for whom a decision has been made by the physician…
- Trial name
- ENVISIOeN (NCT02425462)
- Testing
- Dienogest (Visanne, BAY86-5258)
- Where
- 6 sites in Indonesia, Malaysia and 4 more
- Volunteers
- 895 people
- Sponsor
- Bayer
Chronic Pelvic Pain, Endometriosis
Endometriosis Biomarker Discovery Study
This is a prospective, Single time point, discovery study intending to identify biomarkers that can differentiate endometriosis from other underlying reasons for pelvic pain.
- Trial name
- EMBARK (NCT03272360)
- Sponsor
- Myriad Genetic Laboratories, Inc.
Endometriosis
A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Women With Endometriosis.
The objective of this study is to determine the safety and efficacy of 3 asoprisnil doses (0.5 mg, 1.5 mg, and 5.0 mg) for 12 weeks in women with endometriosis.
- Trial name
- NCT00160433
- Testing
- Asoprisnil
- Volunteers
- 131 people
- Sponsor
- Abbott
Cough, Endometriosis
Study to Gather Information on the Influence of BAY1817080 on the Electrical Activity of the Heart Recorded by an Electrocardiogram in Healthy Male and Female Participants
In this study, researchers want to find whether the study drug BAY1817080 has an effect on the electrocardiogram (ECG). 40 healthy male or female participants with the age of 18 to 65 years will be enrolled into this study.
- Conditions
- Cough, Endometriosis, Overactive Bladder
- Trial name
- NCT04423744
- Testing
- BAY1817080, Moxifloxacin
- Where
- Germany
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bayer
Ovarian Endometrioma
Ovarian Endometrioma Ablation Using Plasma Energy Versus Cystectomy
Objective: To compare loss of ovarian parenchyma following ovarian endometrioma ablation using the PlasmaJet system versus cystectomy, using postoperative examination by 3D ultrasound. Design: Prospective comparative study.
- Trial name
- NCT01596985
- Testing
- Ablation using the PlasmaJet system, Cystectomy
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Plasma Surgical Inc
Endometriosis
Multicenter Validation of the Salivary miRNA Signature of Endometriosis
ENDOmiARN Salive Test is a multicentre external validation study of a salivary signature of endometriosis carried out in France in Obstetrics and Reproductive Medicine departments, in order to evaluate its performance and discuss…
- Trial name
- NCT05244668
- Where
- 18 sites in Canada, France
- Volunteers
- 1,140 people
- Sponsor
- ZIWIG
Lower Abdominal Surgery, Pelvic Surgery
Objective to Evaluate the Safety and Effectiveness of LED Light Source System for Endoscopy in Ureteral Radiography
This clinical trial is a prospective, multi-center, single-blind, parallel, randomized controlled superiority clinical trial. The trial will be carried out in 5 centers, involving 120 subjects as estimated who will be divided…
- Trial name
- IRIS (NCT04561414)
- Testing
- LED light source system for endoscope, Ureteral stent (Cook Ireland Ltd.)
- Where
- 4 sites in China
- Sponsor
- Stryker Orthopaedics