Clinical trials: Endometriosis
Endometriosis
Pain Associated With Endometriosis
This study will evaluate the efficacy and safety of an investigational medication compared with placebo in the treatment of pain associated with endometriosis.
- Trial name
- NCT00758953
- Testing
- Danazol Once Weekly, Danazol Twice Weekly
- Where
- 49 sites in United States, Canada and 1 more
- Volunteers
- 66 people
- Sponsor
- Lumara Health, Inc.
Endometriosis
Global Study to Evaluate the Long-Term Safety and Efficacy of Elagolix in Women With Moderate to Severe Endometriosis-associated Pain
A randomized study evaluating the continued safety and efficacy of elagolix in the management of moderate to severe endometriosis associated pain in adult pre-menopausal women who completed 6 months treatment in pivotal Study…
- Trial name
- NCT02143713
- Testing
- Elagolix
- Volunteers
- 496 people
- Sponsor
- AbbVie
Endometriosis
Open Label Immunotherapy of Endometriosis
Endometriosis is a chronic gynecological disease characterized by sustained painful symptoms that are responsible for a decline in the quality of life of sufferers.
- Trial name
- NCT03340324
- Testing
- V-Endo
- Where
- Mongolia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Immunitor LLC
Dysmenorrhea
Multi-center Clinical Trials of Sanjie Analgesic Capsule in Treating Endometriosis
It is a multi-center, double -blind, placebo -controlled, randomized post-marketing study in Chinese subjects with endometriosis-associated pain to assess treatment effect and safety in the subjects treated with Sanjie Analgesic…
- Trial name
- NCT02031523
- Testing
- Sanjie analgesic capsule
- Where
- 14 sites in China
- Volunteers
- 400 people
- Sponsor
- Jiangsu Kanion Pharmaceutical Co., Ltd
Endometriosis
A Long-term Extension Study of TAK-385 in the Treatment of Endometriosis
The purpose of this study is to compare the long term safety and efficacy of TAK-385, once daily (QD) following continued administration in participants who completed a Phase II dose-finding study.
- Trial name
- NCT01452685
- Testing
- TAK-385, Leuprorelin acetate
- Where
- 69 sites in Japan
- Volunteers
- 397 people
- Sponsor
- Takeda
Endometriosis
The Pharmacokinetic(PK)/Pharmacodynamics(PD) Study of SHR7280 Tablets in Premenopausal Subjects With Endometriosis.
The primary objective of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of SHR7280 tablets in premenopausal subjects with endometriosis.
- Trial name
- NCT04417972
- Testing
- SHR7280
- Where
- China
- Volunteers
- 179 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Endometriosis
A Study Evaluating Food Effect on Pharmacokinetics of HS-10518
The primary objective of this study is to evaluate the effect of food on the pharmacokinetics of HS-10518
- Trial name
- NCT06554548
- Testing
- HS-10518
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Cancer, Pregnancy Related
Distribution of Biospecimens From Biorepositories/Biobanks for Research Use
This protocol seeks to assist biorepositories/biobanks in distributing their stored specimens and data to researchers that will actually utilize them to advance medicine and technology.
- Conditions
- Cancer, Pregnancy Related, Gastro-Intestinal Disorder, Cardio-Respiratory Distress
- Trial name
- NCT03884400
- Testing
- Specimens obtained from surgical, phlebotomy or other non-invasive procedure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- iSpecimen Inc
Endometriosis
Efficacy of Trace Elements in the Treatment of Endometriosis: a Pilot Study
The primary objective of this pilot study is to evaluate the efficacy of trace elements, versus placebo, on the reduction of pain in endometriosis of an American Fertility Society (AFSr) score of 2 to 4, combined or not to an…
- Trial name
- NCT02437175
- Testing
- ENDO 1/ENDO 2
- Where
- Belgium
- Volunteers
- 99 people
- Sponsor
- Laboratoires Pronutri
Endometriosis
Study Of Oral Elagolix Tablets To Assess the Tolerability and Change in Disease Symptoms in Adult Female Participants With Moderate to Severe Endometriosis-associated Pain
Endometriosis is an abnormal, estrogen-dependent growth of endometrial tissue outside the uterus that frequently results in dysmenorrhea and pelvic pain and often causes infertility.
- Trial name
- ENDORSE (NCT04630990)
- Where
- 10 sites in Israel
- Volunteers
- 117 people
- Sponsor
- AbbVie
Endometriosis Related Pain, Overactive Bladder
Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function
BAY1817080 is currently under clinical development to treat pain related to unexplained chronic cough or chronic cough not affected by a treatment (refractory and/or unexplained chronic cough, RUCC), or a condition where the…
- Conditions
- Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
- Trial name
- NCT04471337
- Testing
- BAY1817080
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Dysmenorrhea, Dyspareunia
Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Women
The purpose of the study is to evaluate the efficacy and safety of two doses of ERB-041 (75 mg and 150 mg) relative to placebo on the relief of endometriosis-related symptoms (dysmenorrhea, pelvic pain, and deep dyspareunia) in…
- Conditions
- Dysmenorrhea, Dyspareunia, Endometriosis, Pelvic Pain
- Trial name
- NCT00318500
- Testing
- ERB-041
- Where
- 70 sites in United States, Australia and 5 more
- Volunteers
- 150 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Ovarian Cysts, Endometriosis
Evaluation of Adhexil Safety and Efficacy in Prevention and/or Reduction of Adhesions in Gynecological Surgery
The objective of this study is to evaluate the safety and efficacy of ADHEXIL™ in preventing and/or reducing post-operative adhesions in patients undergoing surgery involving the ovaries.
- Conditions
- Ovarian Cysts, Endometriosis, Adhesions
- Trial name
- NCT00865488
- Testing
- ADHEXIL
- Where
- 5 sites in United States, Germany and 3 more
- Volunteers
- 80 people
- Sponsor
- OMRIX Biopharmaceuticals
Endometriosis, Endometriosis Ovary
Safety, Tolerability and Efficacy of Vaginal Suppositories for Treatment of the Endometriosis
Background: Endometriosis is a chronic gynecological disease with the growth of endometrial tissue outside the endometrium. In all its properties, this tissue is similar to the mucous membrane of the uterus.
- Conditions
- Endometriosis, Endometriosis Ovary, Endometriosis Externa, Endometriosis, Rectum
- Trial name
- ELTA (NCT03481842)
- Testing
- Linifanib, BIBW2992, Axitinib
- Where
- Switzerland
- Sponsor
- BioGene Pharmaceutical Ltd.
Endometriosis
A Clinical Trial to Evaluate Efficacy and Safety of Elagolix Tablets in Women With Moderate or Severe Endometriosis-associated Pain
This is a phase 3, multicenter, double-blind, placebo-controlled, randomized study to evaluate the efficacy and safety of elagolix tablets versus placebo in premenopausal women with moderate or severe endometriosis-associated…
- Trial name
- NCT06076486
- Testing
- Elagolix
- Where
- China
- Volunteers
- 202 people
- Sponsor
- Nanjing Chia-tai Tianqing Pharmaceutical
Endometriosis Related Pain, Overactive Bladder
Study on the Safety of BAY1817080, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug in Participants With Impaired Liver Function or Normal Liver Function
BAY1817080 is currently under clinical development to treat pain related to unexplained chronic cough or chronic cough not affected by a treatment (refractory and/or unexplained chronic cough, RUCC), or a condition where the…
- Conditions
- Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
- Trial name
- NCT04454424
- Testing
- BAY1817080, Midazolam
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Bayer
Endometriosis
A Phase II Randomized Open Label Study of KLH-2109 in Patients With Endometriosis
The purpose of this study is to evaluate the efficacy and safety of KLH-2109 in patients with endometriosis.
- Trial name
- NCT01629420
- Testing
- KLH-2109
- Where
- Japan
- Volunteers
- 20 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Pelvic Pain Associated With Refractory Endometriosis
A Safety & Efficacy Study of BGS649 in Women With Refractory Endometriosis
The purpose of this study is to determine efficacy, safety, tolerability and pharmacokinetics of multiple doses of BGS649 with concurrent daily administration of combined oral contraception in patients with refractory…
- Trial name
- NCT01116440
- Testing
- BGS649
- Where
- 44 sites in United States, Puerto Rico
- Volunteers
- 27 people
- Sponsor
- Mereo BioPharma
Endometriosis
Evaluation of a Nutraceutical for Endometriosis Pain Relief
Based on the EHP-30 questionnaire, the pain score and general well-being of all patients will be assessed with and without taking a specialized nutraceutical.
- Trial name
- NCT04091191
- Testing
- Meta19.01
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Metagenics Europe
Endometriosis
Somatic Stem Cells in Endometriosis
Human endometrium is a very dynamic tissue characterized by cyclical process of proliferation, differentiation and cellular shedding as part of each menstrual cycle. This issue suggests the presence of somatic stem cells.
- Trial name
- NCT01412138
- Testing
- genetic analysis
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Igenomix