Clinical trials: Endometriosis
Endometriosis
Evaluation of Endometrial Stromal Cell Apoptosis in Adenomyosis
Our previous results revealed that the expression of killer inhibitory receptors (KIRs) on NK cells was decreased in eutopic endometrium in women with adenomyosis.
- Trial name
- NCT00172588
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Deep Infiltrating Endometriosis (DIE), Infertility
Ultra-Long GnRH-a Pretreatment for FET Outcomes in Patients With Deep Infiltrating Endometriosis
Deep infiltrating endometriosis is a severe form of endometriosis that may reduce fertility and negatively affect pregnancy outcomes after assisted reproductive treatment.
- Trial name
- DIE-GnRHa-FET (NCT07696351)
- Testing
- Triptorelin (GnRH agonists), Hormone Replacement Therapy (HRT)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Li-jun Ding
Deep Endometriosis
3D Modeling of Deep Endometriosis From Pelvic MRI
This retrospective monocentric study aims to assess the feasibility and clinical relevance of three-dimensional (3D) modeling of deep endometriosis lesions derived from pelvic MRI.
- Trial name
- ENDO-3D (NCT07864883)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Women's Health: Endometriosis
Postural Sway at Menstrual Cyclus
The study was planned with the aim of comparison of postural sway responses at menstrual cycles in women with and without the dysmenorrheal syndrome.
- Trial name
- NCT03586804
- Testing
- dual task
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Endometriosis
Evaluating the Impact of a Novel Cannabinoid Product for Endometriosis
Despite the proliferation of cannabis and cannabinoid products in recent years, little research has been done to determine the impact of these products on womens health conditions, including endometriosis.
- Trial name
- NCT06477406
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mclean Hospital
Endometriosis
Study Evaluating ERB-041 in Endometriosis in Reproductive-Age Women
The purpose of this investigational study is to determine if a study medication is safe and effective in reducing the symptoms associated with endometriosis; if the study medication reduces the need for pain medication for…
- Trial name
- NCT00110487
- Testing
- ERB-041
- Where
- 46 sites in United States
- Volunteers
- 200 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Endometriosis, Ovarian Reserve
Association Between Laparoscopic Removal of Endometriomas and Anti-mullerian Hormone Levels
Laparoscopic excision of endometriotic cysts is the main stream surgical intervention for treatment of endometriosis. However there is evidence that intervention may effect ovarian reserve by destruction of healthy ovarian tissue…
- Trial name
- NCT02685644
- Testing
- Laparoscopic removal of cysts
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ankara University
Endometriosis
MEdical Versus SUrgical Treatments of Rectal Endometriosis
The purpose of this study is to determine whether, in women with deep endometriosis involving the rectum and not intending to get pregnant, continuous hormonal treatment would be followed by better digestive functional outcomes…
- Trial name
- MESURE (NCT01973816)
- Testing
- Triptoreline 11.25 i.v.; Estradiol 0.5% percutaneous gel;, rectal shaving; rectal disc excision; colorectal resection, Cyproterone acetate 50 mg; estradiol 0.5% percutaneous
- Where
- 11 sites in France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Rouen
Fibroid Uterus, Metrorrhagia
A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes
The goal of this randomized clinical trial is to assess the outcomes of total laparoscopic hysterectomy vs subtotal laparoscopic hysterectomy + mini-laparotomy for uterine extraction for benign gynecological conditions in terms…
- Conditions
- Fibroid Uterus, Metrorrhagia, Adenomyosis, Benign Gynecologic Neoplasm
- Trial name
- STORY (NCT06802198)
- Testing
- total hysterectomy, subtotal hysterectomy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Endometrioma
Hemostatic Measures During Laparoscopic Cystectomy for Endometrioma
laparoscopic excision of ovarian endometriotic cysts is generally recommended because it has been associated with a higher spontaneous conception rate, residual ovarian function after the procedure may be affected
- Trial name
- NCT06421857
- Testing
- suturing, bipolar electrocoagulation
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Ain Shams Maternity Hospital
Endometriosis
Assess Safety and Efficacy of Vilaprisan in Subjects With Endometriosis
The primary objective of this study was to assess the efficacy and safety of two doses of vilaprisan compared to placebo in women with symptomatic endometriosis.
- Trial name
- VILLENDO (NCT03573336)
- Testing
- Vilaprisan (BAY1002670)
- Where
- 23 sites in United States, Austria and 6 more
- Volunteers
- 8 people
- Sponsor
- Bayer
Ovarian Endometrioma
The Association Between Ovarian Endometrioma and Lower Urinary Tract Symptoms
To assess the relationship between ovarian endometrioma and lower urinary tract symptoms, sexual function and gastrointestinal symptoms.
- Trial name
- NCT02623244
- Testing
- Laparoscopic oophorocystectomy or oophorectomy
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Pregnancy Related, Pregnancy Complications
Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring
The Relugolix Pregnancy Registry is a prospective, observational cohort study designed to evaluate the association between relugolix-containing therapy exposure during pregnancy and subsequent maternal, fetal, and infant…
- Conditions
- Pregnancy Related, Pregnancy Complications, Pregnancy, High Risk
- Trial name
- NCT05739123
- Testing
- Relugolix-Containing Product
- Where
- United States
- Volunteers
- 728 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
Pneumoperitoneum
CO2 Absorption During Laparoscopy
CO2 absorption from the pneumoperitoneum increases over time during laparoscopic procedures. Adding 4% of oxygen to the carbon dioxide was shown in rabbits to decrease CO2 resorbtion through prevention of mesothelial hypoxia.
- Trial name
- NCT01340989
- Testing
- alteration of the insufflation gas, full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Endometriosis Ovary
Changes in Serum antimüllerian Hormone Levels in Patients 3 and 12 Months After Endometrioma Sclerotherapy
Endometriosis affects 6-10% of women in childbearing age. It is a heterogeneous disease with three different forms: superficial endometriosis (peritoneal), ovarian endometrioma and deep pelvic endometriosis (subperitoneal).
- Trial name
- ENDOPAL AMH (NCT04461899)
- Testing
- Blood test
- Where
- 3 sites in France
- Volunteers
- 53 people
- Sponsor
- Hospices Civils de Lyon
Endometriosis, Pelvic Pain
Endometriosis : Traditional Medicine vs Hormone Therapy
This 36-week study will determine whether traditional Chinese medicine (acupuncture and Chinese herbs) is as effective as hormone therapy for alleviating endometriosis-related pelvic pain.
- Trial name
- NCT00034047
- Testing
- Acupuncture, Chinese Products, Nafarelin
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Endometriosis
Nutritional Intervention for Endometriosis
In a 12-week parallel study, women with a verified diagnosis of endometriosis will be randomly assigned to follow a low-fat plant-based diet or to stay on their usual diets for 12 weeks.
- Trial name
- NCT05175248
- Testing
- Plant-based Intervention Group
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Physicians Committee for Responsible Medicine
Pregnancy Rate
Didroxyprogesterone Promotes Natural Pregnancy in Infertile Patients With Endometriosis
Endometriosis (EM) is an important cause of infertility in women of childbearing age. Laparoscopic surgery is the treatment of EM Related infertility is an important method.
- Trial name
- NCT05467852
- Testing
- didroxyprogesterone
- Volunteers
- 300 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Endometriosis
Superior Hypogastric Nerve Plexus Block With Bupivacaine After Robotic Resection of Endometriosis
Endometriosis is a condition that causes significant pelvic pain and affects 10-15% of reproductive age women. Treatment options area both medical and surgical for pain relief, however with surgical options, past studies have…
- Trial name
- NCT06577233
- Testing
- Bupivacaine Hydrochloride, Normal saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Endometriosis, Uterine Fibrioids
A Study to Evaluate Pregnancy Outcomes in Females Treated With Oral Elagolix Tablets and Capsules
Orilissa is a drug approved for the management of moderate to severe pain associated with endometriosis. Oriahnn is approved for heavy menstrual bleeding due to uterine fibroids.
- Trial name
- NCT04464187
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- AbbVie