Clinical trials: Endometriosis (Diagnosis)
Endometriosis, Infertility
Pesticides and Infertility: Oxidative Stress Via Circulating Cell-free DNA and Gut/Genital Microbiome Signatures in Women With Endometriosis
This project PestiEndoMicro aims to provide an innovative approach, studying endometriosis under the genital and gut microbiota scope.
- Conditions
- Endometriosis, Infertility, Female Fertility, Cell Free DNA
- Trial name
- PestiEndoMicro (NCT07471373)
- Testing
- Circulating DNA analysis, Vaginal microbiota analysis, Endometrial microbiota analysis
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pelvic Pain, Endometriosis
Postoperative Narcotic Use After Laparoscopic Gynecologic Surgery
This will be a prospective, randomized, double blinded placebo-controlled study at Erlanger hospital. Eligible patients who provide consent will be randomized into one of two arms receiving continuous intra-peritoneal local…
- Conditions
- Pelvic Pain, Endometriosis, Pelvic Prolapse
- Trial name
- NCT04118777
- Testing
- Ropivacaine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Tennessee, Chattanooga
Theca Lutein Cyst of Left Ovary
Case Report of Endometrioma in Layers of Broad Ligament.
Objective:To present an extremely rare site of occurrence of endometriotic cyst in the layers of Broad Ligament. Patient:A 32 yrs.old woman,married 4 yrs.,presented to OB-GY Dept.with acute,gnawing pain in lower abdomen and…
- Trial name
- mesosalpinx (NCT02513953)
- Testing
- Laparoscopic
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ruby Hall IVF and Endoscopy Centre
Endometrioma, Ovarian Endometriosis
Evaluation of Ovarian Reserve and Recurrence Rate After DWLS Diode Laser OMA Vaporization
PURPOSE OF THE STUDY The study aims to evaluate the effectiveness of the Dual Wavelength Laser System (DWLS) diode laser on the treatment of endometrioma (OMA), with ablation and vaporization of the cystic capsule without…
- Conditions
- Endometrioma, Ovarian Endometriosis, Ovarian Endometrioma
- Trial name
- OMAlaser (NCT06219044)
- Testing
- laparoscopic endometrioma laser vaporization
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Endometriosis
Blood and Tissue Markers for Improving Diagnosis and Prognosis of Endometriosis. (ENDOBIO)
Endometriosis is a chronic, benign, estrogen-dependent disease characterized by endometrial tissue that is implanted outside the uterus into the ovaries, intestines, or peritoneum but also outside the pelvis.
- Trial name
- ENDOBIO (NCT05339451)
- Testing
- Blood biomarkers
- Where
- 3 sites in Sweden
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Endometriosis Related Pain, Overactive Bladder
Study on the Safety of BAY1817080 How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given to Participants With Moderate Renal Impairment and End Stage Renal Disease Requiring Dialysis Compared With Matched Participants With Normal Renal Function
BAY1817080 is currently under clinical development to treat pain related to unexplained chronic cough or chronic cough not affected by a treatment (refractory and/or unexplained chronic cough, RUCC), or a condition where the…
- Conditions
- Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
- Trial name
- NCT04471337
- Testing
- BAY1817080
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer
Endometriosis, Endometriosis-related Pain
Metabolomic Profile in Women With and Without Endometriosis
The pathogenesis of endometriosis is very complex as several factors, including genetic, environmental and lifestyle-related factors, are involved in the development, progression and maintenance of the disease.
- Conditions
- Endometriosis, Endometriosis-related Pain, Infertility
- Trial name
- METABOLENDO (NCT05496218)
- Testing
- Blood samples
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Endometriosis, Stem Cell Transplant
Bone Marrow Cell Engraftment of the Uterus and Genetic Studies of Reproductive Functioning
Background: Some transplant recipients have been found to have cells in their uterus that come from the donor. Researchers want to study uterine tissue from three different groups of women: (1) healthy volunteers, (2) people who…
- Conditions
- Endometriosis, Stem Cell Transplant, Healthy Volunteers
- Trial name
- NCT01468935
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Endometriosis, Immunity
Innate Immunity, MIcrobiota and Inovative Treatments in Endometriosis
Endometriosis is a chronic inflammatory, polygenic, and multifactorial disease affecting approximately 10% of women of reproductive age, corresponding to over one million women in France.
- Conditions
- Endometriosis, Immunity, Microbiota
- Trial name
- IMIEndo (NCT07078435)
- Testing
- surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines, Blood test, Stool samples
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Endometriosis
Diagnostic and Prognostic Markers of Endometriosis in Menstrual Blood
The goal of this observational study is to identify diagnostic and prognostic biomarkers for endometriosis using menstrual blood, an easily accessible yet overlooked biological fluid in women of reproductive age, affected or not…
- Trial name
- MultiMENDo (NCT06245512)
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Dysmenorrhea, Endometriosis
Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With Dysmenorrhea
Dysmenorrhea affects up to 90% of women of reproductive age and represents a significant public health concern. Beyond prostaglandin-mediated uterine contractions, dysmenorrhea involves central sensitization mechanisms and…
- Trial name
- NCT07645196
- Testing
- Abdominal manual mobilization
- Where
- 2 sites in Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Endometriosis
Thromboxane Function in Women With Endometriosis
The goal of this clinical trial is to compare neurovascular regulation in women with endometriosis and healthy women. The main questions it aims to answer are: Do women with endometriosis have greater blood pressure and pain…
- Trial name
- NCT05962034
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Penn State University
Endometriosis
Ascending Dose Study to Investigate the Safety, Tolerability and Pharmacokinetics of BAY1128688 After Multiple Oral Administrations in Healthy Women
The objective of this trial is to investigate the safety and tolerability of BAY1128688 and to determine the concentration of this substance in blood after repeated administration by the oral route.
- Trial name
- NCT02434640
- Testing
- BAY1128688
- Where
- 3 sites in Germany
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Bayer
Endometriosis, Pelvic Pain
The Safety and Effectiveness of Surgery With or Without Raloxifene for the Treatment of Pelvic Pain Caused by Endometriosis
Many women with lower abdominal pain have endometriosis. Endometriosis is a condition in which the lining of the uterus (endometrium) is found outside of the uterus. The diagnosis of endometriosis is usually made at surgery.
- Trial name
- NCT00001848
- Testing
- Raloxifene
- Where
- United States
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Endometriosis
Clinical Trial the Use of Levonorgestrel-releasing Intrauterine System Versus Etonogestrel Implant in Endometriosis
Randomized clinical trial the use of levonorgestrel releasing intrauterine system. Objectives: To evaluate and compare the efficacy of- levonorgestrel releasing intrauterine system l(LNG-IUS) in relation to the subdermal implant…
- Trial name
- NCT02480647
- Testing
- Levonorgestrel, Etonogestrel
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Endometriosis
Drug-drug Interaction Study Between Orally Administered Rifampicin and Vilaprisan
This study will be conducted in a single center, open-label study with a single group fixed sequence design to evaluate the effect of repeated oral administration of 600 mg RIF(Rifampicin) given once daily over 11 days on the…
- Trial name
- NCT02975440
- Testing
- Rifampicin, Midazolam, BAY1002670_Vilaprisan
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Bayer
Endometriosis, Pelvic Pain
tDCS Versus tsDCS for Endometriosis-related Chronic Pelvic Pain Treatment
The purpose of the study is to compare the analgesic effect of 2 mA anodal direct current stimulation on the right primary motor cortex (M1) (tDCS) with a similar stimulation on the spine (D10) (tsDCS) in healthy volunteers (HV)…
- Conditions
- Endometriosis, Pelvic Pain, Transcranial Direct Current Stimulation, Spinal Cord Stimulation
- Trial name
- DCSErCPP (NCT02958423)
- Testing
- Transcranial DCS Healthy Volunteers, Transspinal DCS Healthy Volunteers, Transcranial DCS CPP patients
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jean Schoenen
Endometriosis
Evaluation of Endometrial Stromal Cell Apoptosis in Adenomyosis
Our previous results revealed that the expression of killer inhibitory receptors (KIRs) on NK cells was decreased in eutopic endometrium in women with adenomyosis.
- Trial name
- NCT00172588
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Endometriosis, Ovarian Hyperstimulation
Assessment and Prevention of Pain During Ovarian Stimulation in Patients With Endometriosis
Randomized double blinded placebo-controlled trial to evaluate the impact of ovarian hyperstimulation on endometriosis-related symptoms and to evaluate the impact of letrozole use during ovarian hyperstimulation with respect to…
- Trial name
- APPOSE (NCT04002141)
- Testing
- Letrozole
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Endometriosis, Endometriosis-related Pain
Microbiota and Immunoassay in Women With and Without Endometriosis: a Pilot Study
Endometriosis is an estrogen-dependent chronic inflammatory disease characterized by the presence of endometrial tissue outside the uterine cavity. This pathology has a prevalence of about 5-10% in reproductive-aged women.
- Trial name
- NCT05433909
- Testing
- Blood, fecal, vaginal and endometrial liquid samples
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico