Clinical trials: Endometriosis-related Pain
Endometriosis
The Impact of Yoga on Endometriosis-Related Pain
The central hypothesis of the investigators is that the practice of yoga will result in an improvement of endometriosis related pain symptoms for women with endometriosis.
- Trial name
- NCT06559852
- Testing
- Yoga
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Milton S. Hershey Medical Center
Endometriosis Related Pain, Overactive Bladder
Study on the Safety of Drug BAY1817080 at Different Doses and the Way the Body Absorbs and Eliminates the Drug in Japanese Healthy Adult Male Participants
Researchers in this study want to learn about the safety of drug BAY1817080 at different doses and the resulting blood levels of the study drug in Japanese healthy adult male participants.
- Conditions
- Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
- Trial name
- NCT04265781
- Testing
- BAY1817080
- Where
- Japan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bayer
Endometriosis, Endometriosis-related Pain
Histologic Comparison of Ablative Techniques for Endometriosis
To our knowledge, no other human studies directly compare the effectiveness of the various ablative technologies. We set out to design a study to directly compare ablative energy sources and evaluate their ability to destroy…
- Conditions
- Endometriosis, Endometriosis-related Pain, Endometriosis Pelvic, Endometriosis; Peritoneum
- Trial name
- NCT06414083
- Testing
- Diathermy, CO2 Laser, Argon Beam Coagulator
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- TriHealth Inc.
Endometriosis
Study to Gather Information How Well Three Different Doses of BAY1817080 Given Twice Daily Over 12 Weeks Work in Comparison to an Inactive Pill (Placebo) and Elagolix in Women Suffering From Pain Related to a Condition Where the Tissue That Usually Grows Inside the Womb Grows Outside of the Womb
The purpose of this study is to assess safety and efficacy of BAY 1817080 compared to elagolix and placebo in women with symptomatic endometriosis.
- Trial name
- SCHUMANN (NCT04614246)
- Testing
- BAY1817080, Elagolix
- Where
- 147 sites in United States, Austria and 18 more
- Volunteers
- 215 people
- Sponsor
- Bayer
Endometriosis
The Sleep-pain Relationship in Women with Endometriosis
The goal of this study is to examine the sleep-pain relationship in women diagnosed with endometriosis, by monitoring different symptoms of endometriosis and sleep through an experience sample method study (ESM).The main question…
- Trial name
- ENDO (NCT06834737)
- Testing
- ecological sampling method
- Volunteers
- 60 people
- Sponsor
- Vrije Universiteit Brussel
Endometriosis, Endometriosis-related Pain
Relugolix for Endometriosis Associated Pain
Endometriosis is a chronic, estrogen-dependent condition frequently associated with pelvic pain and reduced quality of life. Relugolix combination therapy (CT), an oral GnRH receptor antagonist-based treatment, has demonstrated…
- Conditions
- Endometriosis, Endometriosis-related Pain, Pelvic Pain Syndrome
- Trial name
- RELAX (NCT07440043)
- Testing
- Patients with a diagnosis of endometriosis receiving treatment with Relugolix CT, according to clinical practice,
- Volunteers
- 33 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Endometriosis, Chronic Pelvic Pain
Pelvic Floor Muscle Function and Endometriosis-Related Pelvic Pain
Our study aims to investigate the associations between endometriosis-related pelvic pain and pelvic floor muscle strength, endurance, and relaxation ability, as well as quality of life, physical activity, and the presence of…
- Conditions
- Endometriosis, Chronic Pelvic Pain, Pelvic Pain Associated With Endometriosis or Adenomyosis
- Trial name
- NCT07713108
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Endometriosis of Umbilicus, Endometriosis in Scar of Skin
Umbilical Endometriosis: a Comparison of Medical and Surgical Therapy and Pathogenetic Considerations
Endometriosis is the presence of endometrial glands and stroma outside the uterine cavity. About 5% of women of reproductive age suffer from the disease.
- Conditions
- Endometriosis of Umbilicus, Endometriosis in Scar of Skin, Endometriosis-related Pain, Endometriosis
- Trial name
- UMBEND (NCT05367258)
- Testing
- Patients satisfaction after medical and surgical treatment for umbilical endometriosis
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Endometriosis, Quality of Life
Effects of Ashwagandha Supplementation on Quality of Life and Well-Being in Women With Endometriosis
The goal of this clinical trial is to learn how ashwagandha, a herbal dietary supplement, affects quality of life in women with endometriosis. Researchers will also assess how well participants tolerate it.
- Conditions
- Endometriosis, Quality of Life, Pain, Perceived Stress
- Trial name
- Ash_End (NCT07898670)
- Testing
- Ashwagandha
- Where
- Austria
- Volunteers
- 90 people
- Sponsor
- Medical University of Vienna
Endometriosis, Pelvic Pain
Cannabidiol for the Treatment of Pelvic Pain in Endometriosis (DREAMLAND)
The objective of this work is to conduct a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of cannabis extract in women with endometriosis who have already undergone hormonal…
- Trial name
- DREAMLAND (NCT05670353)
- Testing
- Cannabis Derivatives, Hormonal Contraceptive Agents
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Endometriosis, Chronic Pelvic Pain
Continuous Postoperative Use of Low-Dose Combined Oral Contraceptivesfor for Endometriosis-Related Chronic Pelvic Pain
Because ovarian sex steroids fluctuations during the menstrual cycle are implicated in the pathogenesis of the endometriosis-related chronic pelvic pain (CPP), the oral contraceptives (OCs) are used with non-contraceptive…
- Trial name
- NCT00844012
- Testing
- Continuous OC (clormadinone acetate plus ethinil-estradiol - Belara®, Grunenthal, Milan, Italy), Cyclic OC (clormadinone acetate plus ethinil-estradiol)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University Magna Graecia
Endometriosis
The Effect of Selective Oxytocin Receptor Inhibitors on Endometriosis-related Pain
A pilot study to investigate the potential role of atosiban, a selective oxytocin receptor inhibitor, in the management of endometriosis-related pain.
- Trial name
- ENDOBAN (NCT05382143)
- Testing
- Atosiban
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Radboud University Medical Center
Endometriosis
A Phase 2 Trial to Investigate Efficacy and Safety of Vipoglanstat in Women With Endometriosis
The main objective of the trial is to evaluate the efficacy of vipoglanstat on endometriosis-related non-menstrual pelvic pain (NMPP).
- Trial name
- NOVA (NCT07260669)
- Testing
- Vipoglanstat
- Where
- 44 sites in Bulgaria, Czechia and 5 more
- Volunteers
- 213 people
- Sponsor
- Gesynta Pharma AB
Endometriosis, Endoplasmic Reticulum Stress
Relationship Between Endoplasmic Reticulum Stress and Pain in Patients With Endometriosis
The correlation between painful symptoms (dysmenorrhea, dysparonia, dysuria, chronic pelvic pain) symptoms and endoplasmic reticulum stress was investigated in 86 patients diagnosed with endometriosis.
- Conditions
- Endometriosis, Endoplasmic Reticulum Stress, Endometriosis-related Pain
- Trial name
- NCT04440397
- Testing
- xbp-1 - endometriosis patients group
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Endometriosis Related Pain, Quality of Life
Bowel ENDOmetriosis; Evaluation of Diagnostics and Quality of Life
Endometriosis on the bowel is a benign condition that can cause major complaints and severely affect the quality of life of women of fertile age.
- Conditions
- Endometriosis Related Pain, Quality of Life, Pain, Chronic, Bowel Dysfunction
- Trial name
- ENDO (NCT03779256)
- Testing
- 2D transvaginal ultrasound
- Where
- 3 sites in Australia, Austria and 1 more
- Volunteers
- 207 people
- Sponsor
- Oslo University Hospital
Endometriosis, Endometriosis-related Pain
Rimegepant For Endometriosis Pain
The purpose of this study is to evaluate the efficacy of rimegepant 75 mg versus placebo in reducing endometriosis-associated pain (EAP) in women with moderate-to-severe pain and histologically confirmed endometriosis.
- Trial name
- NCT07795125
- Testing
- Rimegepant 75 MG
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Mayo Clinic
Endometriosis
A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 to 49 With Moderate to Severe Endometriosis-related Pain
The purpose of this global Phase 2 study is to determine the efficacy, safety, and tolerability of 3 dose levels of OG-6219 in pre-menopausal women between 18 and 49 years of age (inclusive), who have moderate to severe…
- Trial name
- ELENA (NCT05560646)
- Testing
- OG-6219
- Where
- 86 sites in United States, Belgium and 9 more
- Volunteers
- 354 people
- Sponsor
- Organon and Co
Endometriosis
Letrozole vs Danazol for Endometriosis-Related Pain: Randomized Trial
Background: Endometriosis is a chronic gynecological condition defined by the ectopic presence of endometrial glands and stroma outside the uterine cavity, most commonly diagnosed via laparoscopy.
- Trial name
- LET-DAN RCT (NCT07183787)
- Testing
- Letrozole, danazol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sidra Salman
Endometriosis, Endometriosis-related Pain
The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery
The purpose of this study is to determine a difference in participant reported pain after endometriosis surgery in participants given oral metronidazole versus placebo.
- Trial name
- NCT04554693
- Testing
- Metronidazole Oral
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Endometriosis-related Pain
The HEROES Trial: Hyperbaric Oxygen Therapy for Endometriosis-Related Pain
Endometriosis, is a condition where tissue from the uterus, called endometrium, grows outside of the uterus. This effects up to 10% of women, and can lead to long-lasting, moderate to severe pelvic pain, infertility and other…
- Trial name
- HEROES (NCT06579040)
- Testing
- Monoplace Hyperbaric Chamber (Class III medical device)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Sunnybrook Health Sciences Centre