Clinical trials: Endometritis
Chronic Endometritis
FuKe Qianjin Capsule Plus Antibiotics for Chronic Endometritis
This randomized, double-blind, single-dummy, multicenter clinical study, led by Principal Investigator Xue Fengxia at Tianjin Medical University General Hospital (sponsor and primary trial institution) and funded by Zhuzhou…
- Trial name
- FKQJCE (NCT07485842)
- Testing
- FuKe Qianjin Capsules
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Tianjin Medical University
Chronic Endometritis
Hysteroscopy and CD138+ Plasma Cell Density in Chronic Endometritis
The goal of this observational study is to learn if a hysteroscopy exam alone can find chronic endometritis, a long-lasting inflammation of the lining of the uterus.
- Trial name
- NCT07733713
- Volunteers
- 100 people
- Sponsor
- Centro A.M.B.R.A. (Associazione Medici e Biologi per la Riproduzione Assistita)
Wound Infection or Endometritis Post Cesarean Section
Supplemental Perioperative Oxygen to Reduce the Incidence of Post-Cesarean Endometritis and Wound Infection
The purpose of this study is to determine whether supplemental perioperative oxygen significantly decreases the incidence of post-Cesarean endometritis and wound infection among women who undergo Cesarean section after the onset…
- Trial name
- NCT00670020
- Testing
- supplemental perioperative oxygen
- Volunteers
- 143 people
- Sponsor
- University of Washington
The Primary Outcome of This Study Will be the Rate of Endometritis
Treatment Utility of Postpartum Antibiotics in Chorioamnionitis
To determine if prophylactic postpartum antibiotics are required post-cesarean delivery for pregnancies with treated chorioamnionitis.
- Trial name
- TUPAC (NCT01585129)
- Testing
- Postpartum Antibiotics, No postpartum antibiotics
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Endometritis
The Pharmacokinetics of Azithromycin Prophylaxis for Cesarean Delivery
PKAZ is a single institution study designed to evaluate the optimal dosing parameters for azithromycin for pre-surgical cesarean prophylaxis.
- Trial name
- PKAZ (NCT01464840)
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
A Known Allergy to Antiseptic Soap, Women Who Had Any Infection in the Perioperative Period
Vaginal Antimicrobacterial Preparation Before Cesarean Secation for Endometritis Prevention
The investigators designed a randomized controlled trial to evaluate whether perioperative Vaginal preparation is superior to no Vaginal preparation in decreasing post CS endometritis.
- Conditions
- A Known Allergy to Antiseptic Soap, Women Who Had Any Infection in the Perioperative Period, A Known Allergy to Chlorohexidine Alcohol or Shellfis
- Trial name
- NCT03093194
- Testing
- vaginal preparation before CS with Septal soap and septol., No vaginal preparation before CS with Septal soap and septol.
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Meconium Stained, Azithromycin
Efficacy of Azithromycin in MSAF Cases to Improve Maternal and Neonatal Outcomes
Meconium stained amniotic fluid increases the risk of maternal complications (e.g., dystocia, operative delivery, and postpartum endometritis) and neonatal complications (e.g., sepsis, admission to the neonatal intensive care…
- Conditions
- Meconium Stained, Azithromycin, Postpartum Endometritis
- Trial name
- NCT05118984
- Testing
- Azithromycin capsule (Zithromax, Pfizer) (250 mg)
- Where
- 2 sites in Egypt
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endometritis
Uterine Flora During Elective and Urgent Cesarean Sections
Hypothesis: The bacterial flora of the uterus during elective Cesarean sections differs from the uterine flora during non-elective Cesarean sections.
- Trial name
- NCT00500019
- Where
- Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Endometritis Postpartum, Endometritis
Antibiotic Prophylaxis in Ragged Placental Membranes
In some centres, women are routinely given a course of antibiotics postnatally if ragged placental membranes were present at delivery. The investigators examined the necessity such an intervention.
- Conditions
- Endometritis Postpartum, Endometritis, Membranes; Retained
- Trial name
- NCT03459599
- Testing
- Prophylactic antibiotics, No prophylaxis (Amox-clav withheld)
- Volunteers
- 716 people, healthy volunteers welcome
- Sponsor
- Sarawak General Hospital
Complications; Cesarean Section
Vaginal Cleansing Before Cesarean Delivery to Reduce Infection
The purpose of this study is to test the hypothesis that vaginal cleansing with povidone-iodine solution immediately prior to cesarean delivery reduces postcesarean infectious morbidity.
- Trial name
- NCT02495753
- Testing
- Vaginal Cleansing, Abdominal Cleansing
- Where
- United States
- Volunteers
- 608 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Infertility Unexplained, Abnormal Uterine Bleeding
Diagnostics of Chronic Endometritis in Infertility
Chronic endometritis (CE) is characterized by the presence of atypical plasma cell infiltrates (CD138 positive) in the endometrial stroma.
- Conditions
- Infertility Unexplained, Abnormal Uterine Bleeding, Intrauterine Disorder
- Trial name
- NCT05946655
- Testing
- Ofloxacin + Metronidazole
- Where
- Poland
- Volunteers
- 102 people
- Sponsor
- Jagiellonian University
Chronic Endometritis
Randomized Controlled Trial of Berberine in Combination With Doxycycline in the Treatment of Chronic Endometritis
Study Subjects: Eligible patients were initially diagnosed with chronic endometritis (CE) by CD138 testing through outpatient hysteroscopy.
- Trial name
- NCT07180563
- Testing
- Participants were treated with doxycycline + berberin for chronic endometritis (intervention group)., At present, the commonly used clinical treatment for chronic endometritis is oral doxycycline
- Where
- China
- Volunteers
- 206 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Recurrent Miscarriage
Chronic Endometritis and Benefits of Antibiotics in Women With Recurrent Miscarriage
The aim of the study is to estimate the incidence of CE, evaluate the endometrial microorganism of CE, and investigate the therapeutic benefits of antibiotics for women with unexplained recurrent miscarriage and CE.
- Trial name
- NCT06163092
- Where
- Hong Kong
- Volunteers
- 175 people
- Sponsor
- Chinese University of Hong Kong
Endometritis, Vaginal Cleansing
Vaginal Cleansing With Chlorhexidine Versus Iodine for Prevention of Endometritis
Povidone has been approved for vaginal cleansing in the prevention of endometritis postcaesarean section. chlorhexidine solution which is cheap and readily available as shown to prevent endometritis.The aim of this study is to…
- Conditions
- Endometritis, Vaginal Cleansing, Post Caesarean
- Trial name
- NCT06936475
- Testing
- Povidone-Iodine, Chlorhexidine Gluconate
- Where
- Nigeria
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Chlorhexidine Gluconate Cloths, Infection; Cesarean Section
STRIPES Study: Study To Reduce Infection Post cEsarean Section
The objective of this study is to determine if the use of chlorhexidine gluconate cloths prior to cesarean section reduce the rate of infectious morbidity (i.e. surgical site infections, endometritis).
- Conditions
- Chlorhexidine Gluconate Cloths, Infection; Cesarean Section, Infectious Morbidity, Surgical Site Infections
- Trial name
- NCT02402907
- Testing
- 2% chlorhexidine gluconate (CHG) cloth
- Where
- United States
- Volunteers
- 1,356 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Endometritis, Tuberculous Endometritis
HFNO Reducing the Incidence of Hypoxia for Hysteroscopy Sedated With Propofol
To determine whether high-flow nasal cannula oxygen can reduce the incidence of hypoxia during the procedure of sedated hysteroscopy.
- Conditions
- Endometritis, Tuberculous Endometritis, Subseptate Uterus, Endometrial Polyps
- Trial name
- NCT05049395
- Testing
- High Flow Nasal Cannula oxygen (HFNO), Regular oxygen
- Where
- China
- Volunteers
- 960 people
- Sponsor
- RenJi Hospital
Chronic Endometritis
GnRH Agonist Pretreatment in Persistent Chronic Endometritis Undergoing FET
Women with PCE represent a treatment-resistant phenotype in whom the endometrial inflammatory and immune status remains abnormal despite antibiotic therapy.
- Trial name
- NCT07642700
- Testing
- Conventional estrogen-progesterone artificial cycle for endometrial preparation, GnRH agonist plus estrogen-progesterone for endometrial preparation
- Volunteers
- 150 people
- Sponsor
- Guoxia Yang
Endometritis
Pharmacokinetics and Safety of Ertapenem in the Postpartum Period
The investigators are doing this study to learn more about the dosing and safety of ertapenem in women with suspected serious infections less than 42 days from the delivery of their infant.
- Trial name
- NCT01587495
- Testing
- Ertapenem
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Daniel Benjamin
Obstetric Complication, Postpartum Hemorrhage
Antibiotics During Intrauterine Balloon Tamponade Placement
The goal of this study is to identify whether antibiotics given at the time of placement of an intrauterine balloon tamponade (IBT) will result in reduction of the risk of endometritis.
- Conditions
- Obstetric Complication, Postpartum Hemorrhage, Postpartum Endometritis
- Trial name
- NCT03478163
- Testing
- CeFAZolin 1000 MG, Clindamycin 900 MG in 6 ML Injection
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Cedars-Sinai Medical Center
Postpartum Sepsis, Postpartum Endometritis
Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries
This study, performed over a course of 3 years in 5 collaborating hospitals in Cameroon, Africa, will randomize 750 women in labor with prolonged rupture of membranes ≥ 8 hours or prolonged labor ≥ 18 hours to identical oral…
- Conditions
- Postpartum Sepsis, Postpartum Endometritis, Postpartum Fever
- Trial name
- NCT03248297
- Testing
- Azithromycin, Azithromycin and amoxicillin
- Where
- Cameroon
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham