Clinical trials: Endophthalmitis Following Cataract Surgery
Inflammation Eye
Bromfenac Versus Dexamethasone After Cataract Surgery
The aim of the study is to compare bromfenac to dexamethasone eye drops to control inflammation after cataract surgery. Inflammation in the anterior chamber of the eye will be measured by a Laser Flare Photometer (LFP).
- Trial name
- BVD (NCT03317847)
- Testing
- Bromfenac 0.09 % Ophthalmic Solution, Dexamethasone 0.1% ophthalmic suspension
- Where
- Italy
- Volunteers
- 92 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Inflammation and Pain Following Ocular Surgery
RTA 408 Ophthalmic Suspension for the Treatment of Ocular Inflammation and Pain Following Ocular Surgery
This study assesses the efficacy and safety of two concentrations of RTA 408 Ophthalmic Suspension in the treatment of patients who have inflammation and pain following ocular surgery.
- Trial name
- NCT02065375
- Testing
- Omaveloxolone Ophthalmic Suspension 1.0%, Omaveloxolone Opthalmic Suspension 0.5%
- Where
- 6 sites in United States
- Volunteers
- 109 people
- Sponsor
- Biogen
Endophthalmitis
OTX-14-002: Device Exposure Registry
The objective of the study is to collect post-approval data relative to the incidence of endophthalmitis for cataract surgery patients treated with the FDA-approved ReSure Sealant when used by a broad group of physicians under…
- Trial name
- NCT02309736
- Testing
- ReSure Sealant
- Sponsor
- Ocular Therapeutix, Inc.
Endophthalmitis Following Cataract Surgery
Compare PPV With and Without Silicone Oil in Managing Postoperative Endophthalmitis
Comparing PPV with and without silicone oil in managing postoperative endophthalmitis
- Trial name
- Endopthalmitis (NCT06990607)
- Testing
- Pars plana Vitrectomy, Silicone Oil
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Endophthalmitis
Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery
Intracameral injection of 0.1% moxifloxacin solution after cataract surgery to prevent endophthalmitis
- Trial name
- NCT03244072
- Testing
- Moxifloxacin
- Where
- United States
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- Jason Ahee, M.D.
Cataract, Postoperative Endophthalmitis
Intracameral Levofloxacin Versus Moxifloxacin After Cataract Surgery
This randomized study aims to compare the safety and efficacy of intracameral levofloxacin versus intracameral moxifloxacin administered at the end of phacoemulsification cataract surgery.
- Trial name
- NCT07850414
- Testing
- Levofloxacin, Moxifloxacin
- Volunteers
- 93 people
- Sponsor
- Assiut University
Endophthalmitis Following Cataract Surgery
Conjunctival Flora Before Cataract Surgery: a Microbiological Evaluation
The purpose of the present study is to elucidate the qualitative and quantitative variation of ocular flora after treatment with eyedrops containing 0.6% povidone-iodine in the eye of patients undergoing routine cataract surgery.
- Trial name
- NCT03958292
- Testing
- IODIM
- Where
- 6 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Ospedale Sacra Famiglia - Fatebenefratelli Erba
Endophthalmitis
Evaluation of Efficacy and Safety of Intracameral Moxifloxacin for Prevention of Postcataract Endophthalmitis.
There has thus far been only one randomized and masked clinical trial in the world to evaluate the efficacy of the intraoperative intracameral injection of antibiotics with the objective of preventing endophthalmitis following…
- Trial name
- NCT02770729
- Testing
- Moxifloxacin, No injection of moxifloxacin
- Where
- Brazil
- Volunteers
- 3,640 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Pharmacological Action
Intravitreal Triamcinolone and Moxifloxacin Injection After Cataract Surgery
This study aims to evaluate the short-term effects and safety of prophylactic intra-vitreal injection of triamcinolone-moxifloxacin combination after cataract surgery.
- Trial name
- NCT05428683
- Testing
- intra-vitreal triamcinolone-moxifloxacin injection after cataract surgery as a prophylactic measures against post-operative endophthalmitis
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Emad Abdel Aal Saliem
Endophthalmitis
Preoperative Topical Gatifloxacin on Anterior Chamber Cultures After Cataract Surgery
Postoperative endophthalmitis, a possible severe complication of cataract surgery, is an infection of the anterior chamber of the eye caused by bacterial contamination and colonization through surgical incisions.
- Trial name
- NCT00335231
- Testing
- gatifloxacin ophthalmic (ZYMAR)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Endophthalmitis, Cataract
Early Vitrectomy for Endophthalmitis After Cataract Surgery
Post-operative infectious endophthalmitis is devastating condition that causes a diffuse intraocular inflammation and may lead to blindness.
- Conditions
- Endophthalmitis, Cataract, Vitreous Detachment, Retinal Detachment
- Trial name
- NCT05249413
- Testing
- Early 23-gauge pars-plana vitrectomy
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Benha University
Cataracts
Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis Patients
This study will test the effectiveness of an intraocular lens treated with heparin in reducing or preventing inflammation after cataract surgery in patients with uveitis.
- Trial name
- NCT00001311
- Testing
- heparin-surface modified intraocular lens
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Eye Institute (NEI)
Cataract
To Compare the Safety and Efficacy of Intracameral Levofloxacin and Intracameral Cefazolin in Reducing Rates of Endophthalmitis Following Cataract Surgery.
Patients with senile cataracts undergoing phacoemulsification were assigned to receive intracameral levofloxacin (0.1ml/0.5mg) or intracameral cefazolin (0.1ml/1mg).
- Trial name
- NCT06710977
- Testing
- Safety of intracameral levofloxacin in cataract surgery, Use of intracameral cefazolin in cataract surgery
- Where
- 2 sites in Singapore
- Volunteers
- 50 people
- Sponsor
- Tan Tock Seng Hospital
Endophthalmitis
Study of Antibiotic Prophylaxis for Endophthalmitis Following Cataract Surgery
Cataract is the most important cause of visual impairment and decreased mobility in the elderly. While surgery is usually successful, it is also responsible for permanent loss of vision in up to 0.1% of patients due to severe…
- Trial name
- NCT00136344
- Testing
- Cefuroxime, Levofloxacin
- Where
- 24 sites in Austria, Belgium and 7 more
- Volunteers
- 35,000 people
- Sponsor
- City, University of London