Clinical trials: Endoscopic Assessment
Sedation
Assessment of Sedation During Endoscopy
Use of sedation is often required in endoscopic procedures such as ERCP (endoscopic retrograde cholangiopancreatography). However, assessment of the level of sedation during these procedures is not investigated in detail.
- Trial name
- NCT01747733
- Testing
- Bispectral Index
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Helsinki University Central Hospital
Colonic Disease, Ulcerative Colitis
Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) in Detection & Classification of Ulcerative Colitis
To evaluate the ability of the PillCam® Colon Capsule Endoscope to detect and classify Ulcerative colitis
- Trial name
- NCT00604422
- Where
- 3 sites in Hong Kong, Singapore and 1 more
- Volunteers
- 97 people
- Sponsor
- Medtronic - MITG
GastroIntestinal Bleeding
Effectiveness and Safety of Nexpowder as an Endoscopic Hemostatic Treatment
In patients who show signs of bleeding and bleeding after polypectomy such as EMR and ESD for polyps with a diameter of 2 cm or more in the lower gastrointestinal tract, the effectiveness and safety of Nexpowder as an endoscopic…
- Trial name
- NCT05884931
- Testing
- Nexpowder, Conventional Treatment
- Where
- 3 sites in South Korea
- Volunteers
- 66 people
- Sponsor
- Next Biomedical Co., Ltd.
Non-small Cell Lung Cancer
Assessment of Invasive Mediastinal Staging in cN1 Lung Cancer.
This is a prospective non-randomized multicenter clinical trial performing endobronchial and esophageal ultrasound for mediastinal lymph node staging of operable and resectable cT1-T2-selectedT3 cN1 cM0 NSCLC.
- Trial name
- ASTER2 (NCT01456429)
- Testing
- Thoracic endosonography
- Where
- 3 sites in Belgium, Netherlands
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colonoscopy, Bowel Preparation
BLI800-480: A Safety and Efficacy Evaluation of 2 Different Bowel Cleansing Preparations in Adult Subjects
To compare the safety, tolerance and efficacy of SUPREP Bowel Prep Kit to an FDA approved control as bowel preparations prior to colonoscopy in adult patients.
- Conditions
- Colonoscopy, Bowel Preparation, Endoscopy
- Trial name
- NCT01786629
- Testing
- SUPREP Bowel Prep Kit, FDA approved bowel preparation containing electrolytes
- Where
- 10 sites in United States
- Volunteers
- 338 people
- Sponsor
- Braintree Laboratories
Unresectable Pancreatic Cancer, Advanced Pancreatic Cancer
Safety and Efficacy of NRT6008 in Patients With Unresectable Locally Advanced Pancreatic Cancer (LAPC) and Advanced Pancreatic Cancer With Lymph Node Metastases
This is a single arm, open label, multi-center phase I study, including phase Ia dose escalation and phase Ib dose expansion. Safety review committee (SRC) will be formed to monitor safety and efficacy data through the study.
- Conditions
- Unresectable Pancreatic Cancer, Advanced Pancreatic Cancer, Lymph Node Metastases
- Trial name
- NCT06278454
- Testing
- NRT6008 Injection + Systematic chemotherapy
- Where
- 6 sites in China
- Volunteers
- 58 people
- Sponsor
- Chengdu New Radiomedicine Technology Co. LTD.
Adenomatous Polyp of Colon
Registry Evaluation of a Double Balloon Accessory Device
This study is collecting standard of care information pertaining to the use of the accessory device and patient outcomes when this double balloon accessory device is used during endoscopic procedures in the colon.
- Trial name
- NCT03942965
- Testing
- Double balloon accessory device
- Where
- 3 sites in United States
- Volunteers
- 165 people
- Sponsor
- Lumendi, LLC
Obesity
Incisionless Treatment for Patients With Inadequate Weight Loss Following Roux-en-Y Gastric Bypass
It is estimated that up to 20% of patients who have Roux-en-Y Gastric Bypass (RYGB) surgery will not meet their weight loss goal, or may even regain some of the weight they initially lost.
- Trial name
- NCT00394212
- Testing
- Transoral Suturing
- Where
- 10 sites in United States
- Volunteers
- 77 people
- Sponsor
- C. R. Bard
Breast-Conserving Surgery, Negative Surgical Margins
Endoscopic Breast Conserving Surgery With Intra-operative Navigation System
A growing number of Chinese breast cancer patients are diagnosed at a young age. The quality of life of young breast cancer patients has been a critical issue.
- Conditions
- Breast-Conserving Surgery, Negative Surgical Margins, Endoscopy, Esthetics
- Trial name
- NCT05458414
- Testing
- Intra-operative Navigation System
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Pancreatic Cancer
Training Endoscopists to Perform On-site Rapid Cytological Evaluation for EUS-FNA of Solid Pancreatic Lesions
In China, there is a serious shortage of pathologists who can perform on-site cytological diagnosis. As a result, there are few centers that can conduct ROSE in China, which limits the diagnostic accuracy of EUS-FNA to a certain…
- Trial name
- EUS-FNA (NCT04509687)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changhai Hospital
Esophageal Motility Disorder
Assessment of Esophageal Motility With Transnasal Endoscopy
The purpose of this study is to assese esophageal motor function by simplified transnasal endoscopy compared with esophageal manometry.
- Trial name
- NCT01658865
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Familial Adenomatous Polyposis (FAP), Pouches, Ileoanal
Evaluation of the Ileo-anal Pouch in FAP (ENDOPOL)
This international, multi-centre randomised controlled trial will compare dye-based chromoendoscopy with virtual chromoendoscopy, using NBI/BLI, for adenoma detection during routine surveillance pouchoscopy in adults with…
- Trial name
- ENDOPOL (NCT07726771)
- Testing
- Chromoendoscopy (Indigo Carmine), Virtual Chromoendoscopy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- London North West Healthcare NHS Trust
Esophageal Stenosis Acquired
Mixed Gel of Hydrocortisone and Aluminium Phosphate Preventing Endoscopic Submucosal Dissection Postoperative Stenosis for Patients With Large Esophageal Carcinoma
Endoscopic submucosal dissection as the fastest growing endoscopic treatment technology in the past decade has been widely used in the treatment of early esophageal cancer and gastric cancer without local lymph node metastasis.
- Trial name
- NCT03165344
- Testing
- Hydrocortisone sodium succinate mixed with Aluminium Phosphate gel (route of administration), Triamcinolone Acetonide (route of administration), Prednisone (route of administration)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Peking University Third Hospital
Thyroid
Post Thyroidectomy Endoscopic Laryngeal Examination :Is it Mandatory?
Post thyroidectomy laryngeal nerve injuries are frequently encountered specially in total and near total thyroidectomy some unilateral injuries are not clinically evident and asymptomatic.
- Trial name
- NCT03079193
- Volunteers
- 100 people
- Sponsor
- Khamis Mushayt General Hospital
Gastric Cancer
Web-Mediated Risk Assessment for Endoscopic Screening of Gastric Cancer
Gastric cancer is one of the most common malignancies in China. Early detection is critical for gastric cancer management. However, the diagnosis rate of patients with early gastric cancer is still low.
- Trial name
- NCT03484949
- Testing
- pre-endoscopic screening risk assessment
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- State Key Laboratory of Cancer Biology
Non-Cardiac Chest Pain, Gastroesophageal Reflux Disease
Evaluation of Patients With Non-cardiac Chest Pain
The purpose of this study is to find out how common diseases of the esophagus can cause chest pain. Gastroesophageal reflux disease (GERD), commonly known as heartburn, is a common cause of chest pain in patients that do not have…
- Trial name
- NCT00476398
- Testing
- Capsule endoscopy
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
DISE-HNS Effect Study
The purpose of this study is to assess the site, pattern and degree of upper airway collapse before and during hypoglossal nerve stimulation (HNS) treatment using clinical standard drug-induced sleep endoscopy (DISE) and using a…
- Trial name
- DISE-HNS (NCT06372847)
- Testing
- Hypoglossal nerve stimulation implant, Polysomnography, Drug-induced sleep endoscopy (DISE)
- Where
- Belgium
- Volunteers
- 58 people
- Sponsor
- University Hospital, Antwerp
Barrett Esophagus, Barrett Esophagus Adenocarcinoma
"Less-is-more in Barrett-surveillance" Care Evaluation of Barrett's Patients With Low-Risk in Whom Endoscopic Surveillance is Stopped. The BLISS Project.
Rationale: Until recently, the conventional strategy outlined by both national and international guidelines for managing non-dysplastic (ND) Barrett esophagus (BE), involved endoscopic surveillance at 3 to 5 year intervals…
- Trial name
- BLISS (NCT06803147)
- Testing
- Discontinued endoscopic surveillance
- Where
- Netherlands
- Volunteers
- 3,156 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pediatrics, Colon Capsule Endoscopy
Evaluation Of The Pillcam™ Colon Capsule Endoscopy (Pcce-2) In Pediatric Ulcerative Colitis
This prospective pilot study of 30 pediatric subjects, that are indicated for standard colonoscopy due to follow-up of ulcerative colitis (UC), examines the Given Diagnostic System and the PillCam Colon Capsule in comparison to…
- Trial name
- NCT01740349
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Azienda Policlinico Umberto I
Common Bile Duct Stones
Effect of a Deep Learning-based Bile Duct Scanning System on the Diagnostic Accuracy of Common Bile Duct Stones During Examination by Novice Ultrasound Endoscopists
The bile duct scanning system based on deep learning can prompt endoscopists to scan standard stations and identify bile ducts and stones in real time.
- Trial name
- NCT05381064
- Testing
- artificial intelligence assistance system
- Volunteers
- 184 people
- Sponsor
- Renmin Hospital of Wuhan University