Clinical trials: Endoscopic Assessment, open to volunteers
Post-Bariatric Hypoglycemia
Dietary, Medication, and Endoscopic Interventions for Post-Bariatric Hypoglycemia
Post-bariatric hypoglycemia (PBH) is a complication of upper gastrointestinal surgery that causes recurrent episodes of low blood sugar after eating and can substantially impair quality of life.
- Trial name
- NCT07878494
- Testing
- Dietary Intervention, GLP-1 receptor agonist or Dual GIP/GLP-1 receptor agonist, Transoral Outlet Reduction (TORe)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Acute Variceal Bleed
A Randomized Controlled Trial to Assess the Role of Emergent vs Early Endoscopy in Child B and C Cirrhotic Patients With Acute Variceal Bleed (AVB)-EARLY - AVB
Summary-Variceal bleeding - 70% of all upper gastro-intestinal bleeding episodes in patients with portal hypertension, and they result from esophageal varices (EVs), gastric varices (GVs), or ectopic varices.
- Trial name
- NCT06785701
- Testing
- Upper Gastrointestinal Endoscopy
- Where
- India
- Volunteers
- 220 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Colorectal Cancer, Colorectal Polyp
Safety Of ColoRectal Assessment and Tumor Evaluation by Colon Capsule Endoscopy
Following European guidelines patients undergoing colonoscopy in one of Odense University Hospitals units will now be offered a colon capsule endoscopy (CCE) in case of incomplete examinations.
- Trial name
- SOCRATEC (NCT04307901)
- Testing
- Colon capsule endoscopy
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Odense University Hospital
Superficial Esophageal Cancer, Oesophageal Adenocarcinoma
Multicenter Prospective Cohort on Esophageal Endoscopic Submucosal Dissection
In France in 2018, there were an estimated 2,074 new cases of esophageal adenocarcinoma and 3,224 cases of squamous cell carcinoma.
- Conditions
- Superficial Esophageal Cancer, Oesophageal Adenocarcinoma, Oesophageal Squamous Cell Carcinoma, Barretts Esophagus With Dysplasia
- Trial name
- FEO (NCT07343869)
- Where
- 7 sites in France
- Volunteers
- 750 people
- Sponsor
- Société Française d'Endoscopie Digestive
Frailty, Comorbidities and Coexisting Conditions
Frailty in Outpatient Digestive Endoscopy
The increase in our society of the proportion of frail people who suffer from disability and dependency forces us to detect modifiable factors and therefore subject to intervention that can adapt health care for frail patients in…
- Conditions
- Frailty, Comorbidities and Coexisting Conditions, Complication
- Trial name
- FRIEND (NCT06507527)
- Testing
- Collection of variables
- Where
- Spain
- Volunteers
- 1,474 people
- Sponsor
- Parc de Salut Mar
Gynecomastia
Comparison of Endoscopic and Open Surgery for Gynecomastia
The goal of this observational study is to compare the clinical outcomes, safety, and patient satisfaction of endoscopic versus conventional open surgical techniques in adult male patients undergoing surgery for gynecomastia.
- Trial name
- NCT07653152
- Testing
- Endoscopic Nipple-Areola Complex-Preserving Mastectomy, Conventional Open Nipple-Areola Complex-Preserving Mastectomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Antalya City Hospital
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Non-invasive Breast Cancer
Endoscopy/Robotic Assisted Nipple Skin Sparing Mastectomy
Non-inferiority study of video-assisted (endoscopic or robotic) skin- and nipple-sparing mastectomy compared to open mastectomy. The feasibility of the technique, oncological safety and cosmetic results will be studied.
- Conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Non-invasive Breast Cancer, High Risk Breast Carcinoma
- Trial name
- NCT06823414
- Testing
- Video assisted mastectomy
- Where
- Spain
- Volunteers
- 126 people
- Sponsor
- Alejandra García-Novoa
Type 2 Diabetes Mellitus (T2DM)
Endoscopic Band Ligation for Type 2 Diabetes Mellitus (ENDOBAND-DM)
This is a pilot clinical study evaluating the safety and feasibility of Endoscopic Band Ligation (ENDOBAND-DM) applied to the second through fourth parts of the duodenum - from just distal to the ampulla of Vater to the ligament…
- Trial name
- ENDOBAND-DM (NCT07117721)
- Testing
- Endoscopic Band Ligation (ENDOBAND-DM)
- Volunteers
- 10 people
- Sponsor
- El Katib Hospital
Type 2 Diabetes Mellitus (T2D), Obesity (BMI>30)
Impact of Endoscopic Sleeve Gastroplasty (ESG) in Obese Adults With Type 2 Diabetes (T2D)
The goal of this clinical trial is to determine whether Endoscopic Sleeve Gastroplasty (ESG)-induced weight loss can improve glycemic outcomes and alter the trajectory toward insulin dependence in adults with obesity and…
- Trial name
- MEASURE (NCT07639684)
- Testing
- ESG with OverStitch
- Volunteers
- 50 people
- Sponsor
- Boston Scientific Corporation
Eosinophilic Gastritis, Gastroparesis
Study of Gastric Motility in Eosinophilic Gastritis
Purpose: The study is a cross-sectional observational study designed to determine if eosinophilic gastritis (EG) results in gastric motility impairment.
- Conditions
- Eosinophilic Gastritis, Gastroparesis, Gastric Motility Disorder
- Trial name
- OAT-FEED (NCT05229432)
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
GI Endoscopy
Evaluation of the Incidence of Myocardial Damage Following Upper and Lower Gastrointestinal Endoscopy in High-risk Patients
Hypoperfusion occurs following anaesthesia induction as a result of: 1. a reduction in venous return and cardiac output subsequent to the dilatation of the venous reservoir, and 2.
- Trial name
- NCT07179549
- Volunteers
- 120 people
- Sponsor
- European Society of Anaesthesiology
Unresectable Pancreatic Cancer, Advanced Pancreatic Cancer
Safety and Efficacy of NRT6008 in Patients With Unresectable Locally Advanced Pancreatic Cancer (LAPC) and Advanced Pancreatic Cancer With Lymph Node Metastases
This is a single arm, open label, multi-center phase I study, including phase Ia dose escalation and phase Ib dose expansion. Safety review committee (SRC) will be formed to monitor safety and efficacy data through the study.
- Conditions
- Unresectable Pancreatic Cancer, Advanced Pancreatic Cancer, Lymph Node Metastases
- Trial name
- NCT06278454
- Testing
- NRT6008 Injection + Systematic chemotherapy
- Where
- 6 sites in China
- Volunteers
- 58 people
- Sponsor
- Chengdu New Radiomedicine Technology Co. LTD.
Artificial Intelligence Assistance in Endoscopy Recovery, AI Validation
AI Assistance in GI Endoscopy Recovery Assessment
We have developed and validated an AI model to assess endoscopy recovery status based on 400 voice recordings from 200 patients. This model has a mean accuracy of 84.14% with a mean area under the curve (AUC) of 0.91.
- Trial name
- AIVR2 (NCT06923059)
- Testing
- AI-assisted endoscopy recovery assessment
- Where
- Hong Kong
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Neoplasms, Colonic Polyps
Evaluation of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for Detection and Optical Characterization of Colorectal Lesions: A Prospective Randomized Controlled Study
This prospective randomized controlled study aims to evaluate the diagnostic accuracy of Versatile Intelligent Staining Technology (VIST) and Spectral Flexible Imaging (SFI) for detection and optical characterization of…
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Adenoma, Serrated Polyps
- Trial name
- INSIGHT (NCT07797361)
- Testing
- White Light Endoscopy, Versatile Intelligent Staining Technology, Spectral Flexible Imaging
- Where
- Brazil
- Volunteers
- 990 people
- Sponsor
- Alexandre Vontobel Padoin
Pancreatic Neoplasms, Pancreatic Solid Lesions
EUS-DFI in Solid Pancreatic Lesions
This prospective, international, multicenter observational study aims to evaluate the role of Endoscopic Ultrasound-guided Detective Flow Imaging (EUS-DFI) in the characterization of solid pancreatic lesions.
- Trial name
- DFI (NCT07763561)
- Volunteers
- 48 people
- Sponsor
- Julio Iglesias García
Sedation, Endoscopy
Opioid-Free Versus Opioid-Based Sedation for Endoscopic Procedures
This study will compare two different sedation approaches used during gastroscopy, colonoscopy, and endoscopic retrograde cholangiopancreatography (ERCP).
- Conditions
- Sedation, Endoscopy, Colonoscopy, Endoscopic Retrograde Cholangiopancreatography (ERCP)
- Trial name
- NCT07649746
- Testing
- Dexmedetomidine, Remifentanil
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Stomach Cancer, Diagnosis
Evaluation of the NEOmom® Gastric Video Capsule for Gastric Cancer Screening
Gastric cancer remains a major public health concern, with approximately 6,600 new cases diagnosed each year in France. Despite therapeutic progress, its overall prognosis is still poor: the 5-year survival rate across all stages…
- Conditions
- Stomach Cancer, Diagnosis, Endoscopy of Stomach (Procedure)
- Trial name
- NEOTOGAS (NCT07323186)
- Testing
- Magnetically controlled video capsule endoscopy (MC-VCE)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Chronic Rhinosinusitis (CRS), Nasal Polyps
Triamcinolone Nanocapsules After Endoscopic Nasal Surgery
This randomised, single-masked, parallel-group clinical trial will evaluate the efficacy and safety of a topical triamcinolone acetonide-loaded polymeric nanocapsule formulation for postoperative care following endoscopic nasal…
- Conditions
- Chronic Rhinosinusitis (CRS), Nasal Polyps, Postoperative Healing After Endoscopic Nasal Surgery
- Trial name
- NCT07714525
- Testing
- Triamcinolone Acetonide-Loaded Polymeric Nanocapsules, Normal Saline Nasal Irrigation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Deraya University
Acute Pancreatitis
A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis
The goal of this clinical trial is to test the safety and effectiveness of a single dose of RABI-767 given by endoscopic ultrasound (EUS) guided peripancreatic injection in participants with predicted severe acute pancreatitis.
- Trial name
- NCT06080789
- Testing
- RABI-767
- Where
- 16 sites in United States, India
- Volunteers
- 36 people
- Sponsor
- Panafina, Inc.
Esophagogastroduodenoscopy, Simethicone
Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy
The goal of this randomized, double-blind, placebo-controlled clinical trial is to assess whether the combination of N-acetylcysteine and simethicone improves mucosal visibility during upper gastrointestinal endoscopy in adults…
- Conditions
- Esophagogastroduodenoscopy, Simethicone, N-Acetylcysteine, Premedication
- Trial name
- NACSIMET (NCT07245095)
- Testing
- Premedication with n-acetylcysteine, Premedication with simethicone
- Where
- 2 sites in Mexico
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexicali