Clinical trials: Endoscopic Assessment
Pancreatic Cancer
Evaluation of MMR Status and PD-L1 Expression Using Specimens Obtained by EUS-FNB in Patients With Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) has a suboptimal response to standard therapies that modestly impact survival due to its ability to evade host immune surveillance.
- Trial name
- SUCCESS (NCT03820921)
- Testing
- EUS-FNB, Immunohistochemistry
- Volunteers
- 30 people
- Sponsor
- Ponderas Academic Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Bronchioscopic Lung Volume Reduction (BLVR)
For patients with emphysema, lung volume reduction by insertion of endobronchial valves could be an expedient approach to improve the diaphragm function and the strength of breathing muscles.
- Trial name
- BLVR (NCT02415478)
- Testing
- endoscopic lung volume reduction by valves
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- RWTH Aachen University
Evaluation of Association Between Opiate Use and Biliary Dilation
Opiate Use and Biliary Dilation
We hope to better define the association between opiate use and biliary dilation, which was evident in our previous retrospective study.
- Trial name
- NCT03870347
- Testing
- Endoscopic ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Bowel Cleanliness
A Study of PICOPREP in Patients Needed to Clean the Bowel Prior to X-ray Examination, Endoscopy or Surgery.
The study serves as a confirmation of safety, tolerance and efficacy of PICOPREP in clinical practice.
- Trial name
- NCT01292109
- Testing
- sodium picosulphate
- Where
- 3 sites in Czechia
- Volunteers
- 252 people
- Sponsor
- Ferring Pharmaceuticals
Rectal Cancer, Colo-rectal Cancer
Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery
When a patient is diagnosed with a rectal (bowel) polyp or cancer, radiology doctors read MRI scans to describe how deeply the cancer invades into the bowel wall (this is the 'stage' of the cancer).
- Trial name
- PRESERVE (NCT04103372)
- Testing
- MRI scan, Radiologist training
- Where
- 23 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Imperial College London
Lymph Nodes, Esophageal Cancer
Interobserver Agreement of Endoscopic Ultrasonography and Endoscopic Sonoelastography in the Evaluation of Lymph Nodes
Endoscopic ultrasound (EUS) is an important part of the pre-treatment evaluation of patients with upper gastrointestinal tract cancer (esophageal, gastric, pancreatic and liver cancer).
- Conditions
- Lymph Nodes, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT01033695
- Where
- Denmark
- Volunteers
- 74 people
- Sponsor
- Odense University Hospital
Barrett Esophagus, Esophagus
TECR & ECM Placement for Esophageal High Grade Dysplasia
This study will test the safety and effectiveness of esophageal transoral endoscopic circumferential resection (TECR) using an extracellular matrix (ECM) placement to treat Barrett's esophagus in patients with high-grade…
- Conditions
- Barrett Esophagus, Esophagus, High Grade Dysplasia
- Trial name
- NCT02396745
- Testing
- Subjects undergoing TECR with ECM placement (ACell MatriStem, Boston Scientific WallFlex))
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Breast Cancer
Nipple Aspiration, Ductal Lavage, and Duct Endoscopy in Screening Women at Moderate-to-High Risk of Developing Breast Cancer
RATIONALE: Screening tests, such as nipple aspiration, ductal lavage, and breast duct endoscopy, may help doctors detect cancer cells early and plan more effective treatment for breast cancer.
- Trial name
- NCT00081003
- Testing
- gene expression analysis, protein expression analysis, cytology specimen collection procedure
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Feeding Tube, Dysphagia
Safety and Usability Evaluation of the Fidmi Low-Profile Enteral Feeding Device
A First In Human Usability Open Label trial will be performed using the Fidmi Feeding device on 20 adult patients with a need for enteral feeding.
- Trial name
- Fidmi (NCT03007511)
- Testing
- Fidmi enhanced enteral feeding device
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Fidmi Medical
Benign Prostatic Hyperplasia (BPH)
French Aquablation Clinical Investigation Using Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue
Single arm, multi-center prospective clinical trial to determine the safety and effectiveness of the AQUABEAM System in the treatment of benign prostatic hyperplasia (BPH) in men 45 to 80 years of age.
- Trial name
- NCT03191734
- Testing
- AQUABEAM System
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- PROCEPT BioRobotics
Pancreatic Neoplasms, Pancreatic Cancer
On-site Cytopathology EUS-FNA
This study is a multicenter prospective randomized controlled trial. Potential participants in this study include patients referred for Endoscopic Ultrasound-guided fine needle aspiration (EUS-FNA) of a solid pancreatic lesion at…
- Trial name
- NCT01386931
- Testing
- EUS-guided FNA performed with on-site Cytopathologist, EUS-guided FNA performed without on-site Cytopathologist
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- University of Colorado, Denver
Anemia, Iron-Deficiency
Gastrointestinal Evaluation in Young Men With Iron Deficiency Anemia
Both upper gastrointestinal endoscopy and colonoscopy are recommended in men and post-menopausal women with iron deficiency anemia.
- Trial name
- NCT00498511
- Testing
- upper gastrointestinal endoscopy, colonoscopy
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Small Bowel Disease, Inflammatory Bowel Disease
Evaluation of PillCam® Express Capsule Endoscopy Delivery System
The purpose of this study is to evaluate the safety and efficacy of a trans-endoscopic capsule placement Capsule Endoscopy Delivery System.
- Trial name
- RD-300 (NCT01088646)
- Testing
- PillCam® Express Capsule Endoscopy Delivery System
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medtronic - MITG
Laparoscopic Abdominal Surgery
Evaluation of Safety and Efficacy of Using EndoClear-Endoscopic Lens Cleaning Device
Virtual Ports, Ltd., has developed a lens cleaning device, EndoClear, which is attached to the internal abdominal wall at the beginning of a surgical case and remains in position until completion of the surgery, enabling the…
- Trial name
- NCT01197222
- Testing
- EndoClear Lens Cleaning Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Oregon Clinic
Dysphagia
Dysphagia in Oculopharyngeal Muscular Dystrophy (OPMD)- Evaluation, Endoscopic Examination of Swallowing, Treatment and Long Term Follow up
The investigators aimed to review the natural history of dysphagia and dysphonia in OPMD in order to identify the best candidates and the proper timing to perform dysphagia alleviating procedures in both heterozygote and…
- Trial name
- OPMD (NCT01167439)
- Testing
- Upper esophageal sphincter myotomy
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hillel Yaffe Medical Center
Esophageal Achalasia
Assessment of Different Modified POEM for Achalasia
The aims of this study is to compare the efficacy and safety of conventional myotomy (circular myotomy) and modified myotomy (full-thickness myotomy) in the treatment of achalasia patients.
- Trial name
- NCT04578769
- Testing
- conventional myotomy, full-thickness myotomy
- Where
- China
- Volunteers
- 69 people
- Sponsor
- Peking Union Medical College Hospital
Endoscopic Ultrasonography, Artificial Intelligence
To Evaluate the Capability of an EUS Automatic Image Reporting System
In this study, the EUS intelligent picture reporting system can automatically generate reports after reading videos of EUS examinations.
- Trial name
- NCT05858827
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Renmin Hospital of Wuhan University
Thyroid Diseases
The Feasibility and Safety of the TOETVA for Benign Thyroid Nodules
Thyroid surgery has been developed as a new technique for zero scar in surgery by applying transoral endoscopic thyroidectomy with sublingual approach.
- Trial name
- NCT03158961
- Testing
- Transoral endoscopic thyroidectomy vestibular approach
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The University of Hong Kong
Non Functioning Pancreatic Endocrine Tumor
Diagnostic Accuracy of Preoperative Diagnostic Procedure in the Assessment of Lymph Node Metastases by NF-PanNENs
Pancreatic Neuroendocrine Neoplasms (PanNEN) are a heterogeneous group of neoplasms that arise from the endocrine cells of the pancreatic gland.
- Trial name
- NCT03918759
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Pouchitis, Ulcerative Colitis
Assessment of Patients With Acute Pouchitis Treated With Antibiotics
The purpose of this study is to evaluate the reliability and responsiveness of symptoms, endoscopic, and histological items for assessing pouchitis disease activity in patients undergoing standard of care (SOC) antibiotic therapy…
- Trial name
- NCT05252273
- Testing
- Observational, No intervention
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 43 people
- Sponsor
- Alimentiv Inc.