Clinical trials: Endoscopic Submucosal Dissection, active
Early Rectal Neoplasms
The Application of a Novel Endoluminal Robotic System for Colorectal Endoscopic Submucosal Dissection
Endoluminal surgery through natural orifices is an effective, "incisionless" treatment for benign lesions and early-stage cancers in the urinary tract and gastrointestinal (GI) tract.
- Trial name
- NCT07486180
- Testing
- Colorectal Endoscopic Submucosal Dissection (ESD) Using the Intilume Surgical System
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Chinese University of Hong Kong
Early Gastric Cancer, Colon Neoplasia
Magnetic Guided Counetrtraction During Endoscopic Submucosal Dissection
Endoscopic submucosal dissection (ESD) is a technique that allows curative treatment of early gastrointestinal neoplasia with organ preservation. However, it is a technically demanding procedure.
- Trial name
- NCT06962293
- Testing
- MAG-ESD assisted ESD
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Superficial Esophageal Cancer, Oesophageal Adenocarcinoma
Multicenter Prospective Cohort on Esophageal Endoscopic Submucosal Dissection
In France in 2018, there were an estimated 2,074 new cases of esophageal adenocarcinoma and 3,224 cases of squamous cell carcinoma.
- Conditions
- Superficial Esophageal Cancer, Oesophageal Adenocarcinoma, Oesophageal Squamous Cell Carcinoma, Barretts Esophagus With Dysplasia
- Trial name
- FEO (NCT07343869)
- Where
- France
- Volunteers
- 750 people
- Sponsor
- Société Française d'Endoscopie Digestive
Colorectal Cancer
Recurrence Rate After Endoscopic Resection of , Laterally Spreading Tumor Granular Type (LST-G) of the Colon and Rectum: Endoscopic Mucosal Resection vs. Endoscopic Submucosal Dissection
Colorectal cancer is one of the leading causes of cancer-related mortality worldwide. Early-stage non-polypoid neoplastic lesions, particularly Laterally Spreading Tumors - Granular Type (LST-G) larger than 20mm, require…
- Trial name
- ESD vs EMR (NCT06815406)
- Testing
- Endoscopic Mucosal Resection (EMR), Endoscopic Submucosal Dissection (ESD)
- Where
- 5 sites in Italy
- Volunteers
- 282 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Colorectal Neoplasms
Follow-up After Oncological Resection by Endoscopic Colorectal ESD (Endoscopic Submucosal Dissection)
Colorectal cancer is a common and leading cause of death. Pre-cancerous lesions, as well as some so-called superficial cancers, can be resected via endoscopy.
- Trial name
- FORCE (NCT07871227)
- Testing
- Surgery, Radiochimiotherapy
- Where
- 14 sites in France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Bordeaux
Endoscopic Submucosal Dissection, Target Controlled Infusion of Propofol
Comparison of the Effects of Target-Controlled Infusion Method and Manual Propofol Administration on Respiratory Function, Recovery, and Electroencephalogram in Endoscopic Submucosal Dissection Cases
Endoscopic submucosal dissection (ESD) has become widely used as a minimally invasive alternative for the resection of early-stage gastrointestinal neoplasms.
- Conditions
- Endoscopic Submucosal Dissection, Target Controlled Infusion of Propofol, Endoscopy Unit, Respiratory Complications
- Trial name
- NCT07305857
- Testing
- manuel propofol and target controlled infusion propofol
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Interstitialoma, Endoscopic Surgery
A Study on the Safety and Effectiveness of Endoscopic Intracavitary Submucosal Dissection for Gastric Extracavitary-Type Submucosal Tumors
The aim of this study is to explore the safety and efficacy of endoscopic surgery in the treatment of extraluminal growing stromal tumors
- Trial name
- NCT07337980
- Testing
- Extraluminal growing stromal tumors treated endoscopically
- Volunteers
- 20 people
- Sponsor
- Zhongda Hospital
Esophageal Cancer
Chemoradiotherapy Versus Esophagectomy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma
This is a randomized noninferiority multicenter trial. Patients will be stratified according to the participating hospital. Patients will be randomized to one of the treatment arms.
- Trial name
- ASSURE (NCT03306901)
- Testing
- Esophagectomy, 5-fluorouracil, Cisplatin
- Where
- 9 sites in South Korea
- Volunteers
- 240 people
- Sponsor
- Samsung Medical Center
Gastric Polyps, Intestinal Polyps
Recurrence After Gastric and Intestinal Polyp Resection
This is a retrospective and prospective cohort study designed to evaluate the recurrence rate and identify risk factors after endoscopic resection of gastric and intestinal polyps.
- Conditions
- Gastric Polyps, Intestinal Polyps, Colon Polyps, Colorectal Polyps
- Trial name
- RAGIP (NCT07314554)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- LanZhou University
Esophageal Neoplasm, Esophageal Polyp
Novel Bipolar Radiofrequency Ablation Knife in Esophageal Lesions
Both Baylor St Luke's Medical Center and Mayo Scottsdale are considered endoscopic submucosal dissection (ESD) centers of excellence.
- Conditions
- Esophageal Neoplasm, Esophageal Polyp, Endoscopic Submucosal Dissection, Bipolar Electrocautery
- Trial name
- NCT06476678
- Testing
- Speedboat™ Ultraslim
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
Non-pedunculated Colorectal Polyp Size > 20 mm
Comparison of Efficacy and Safety of Speedboat Device and Needle Knife for Colorectal Endoscopic Submucosal Dissection: a Multicenter Randomized Study
The goal of this clinical trial is to learn whether a new endoscopic device called the Speedboat works as well or better than the standard needle knife for removing large colonic nonpedunculated polyps.
- Trial name
- NCT07754955
- Testing
- Speedboat, Needle knife
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Neoplasms, Colorectal
Endoscopic Mucosal Resection Versus Endoscopic Submucosal Dissection for Colorectal Laterally Spreading Lesions.
EMR and ESD are both effective and safe and are associated with a very low risk of procedure related mortality when performed for colorectal laterally spreading lesions (LSL).
- Trial name
- intERsection (NCT04593407)
- Testing
- Endoscopic mucosal resection (EMR), Endoscopic submucosal dissection (ESD)
- Where
- Spain
- Volunteers
- 236 people
- Sponsor
- José Carlos Marín Gabriel
Early Gastric Cancer
Sentinel Node Resection With or Without LECS After Noncurative ESD for EGC
For patients with non-curative resection after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC), complementary surgery is generally recommended.
- Trial name
- Co-SNARE (NCT07295002)
- Testing
- ICG-guided lymphadenectomy, Laparoscopic and endoscopic cooperative surgery (LECS)
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Region Stockholm
Endoscopic Submucosal Dissection (ESD)
Efficacy and Safety of the RDI Mode in Endoscopic Submucosal Dissection
Conventional white-light endoscopy (WLE) is hampered by insufficient contrast when attempting to identify deep vessels and active bleeding sites; visibility drops further when blood pools or spurts obscure the field, resulting in…
- Trial name
- RM-ESD (NCT07366489)
- Testing
- RDI
- Volunteers
- 158 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Polyps Colorectal
Testing of GripTract-GI Endoscopic Tissue Manipulator for Use During Complex Endoscopic Polypectomies in the Colon
The goal of this clinical trial is to compare the safety and effectiveness of the GripTract GI Endoscopic Tissue Manipulator to the current standard of care for complex polypectomies in adults.
- Trial name
- NCT06015607
- Testing
- Control (via ESD using standard of care), GripTract
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Actuated Medical, Inc.
Stomach Cancer, Undifferentiated Type
Comparison of Endoscopic Resection and Surgery for Early Gastric Cancer With Undifferentiated Histological Type
This multi-center, randomized controlled trial is designed to evaluate clinical effectiveness and cost-effectiveness of ESD for undifferentiated type of EGC meeting the expanded indication compared with surgery.
- Conditions
- Stomach Cancer, Undifferentiated Type, Expanded Indication of Endoscopic Resection
- Trial name
- ERASE-GC (NCT04890171)
- Testing
- Endoscopic submucosal dissection, Surgery
- Where
- South Korea
- Volunteers
- 708 people
- Sponsor
- National Cancer Center, Korea
Rectal Neuroendocrine Tumor
Traction-Assisted Versus Conventional Endoscopic Submucosal Dissection for Rectal Neuroendocrine Tumors
This prospective, randomized pilot study will compare traction-assisted endoscopic submucosal dissection (T-ESD) with conventional endoscopic submucosal dissection (C-ESD) for the treatment of rectal neuroendocrine tumors.
- Trial name
- TRACE-NET (NCT07848360)
- Testing
- Traction-Assisted Endoscopic Submucosal Dissection, Conventional Endoscopic Submucosal Dissection
- Volunteers
- 66 people
- Sponsor
- Pusan National University Hospital
Colorectal Cancer, Colorectal Neoplasms
Clinical Outcomes After EMR or ESD of Colorectal Neoplasms - A Multicenter Registry
This study aims to establish a multicenter registry platform to capture clinical data from subjects undergoing colorectal EMR and ESD.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenoma
- Trial name
- NCT05653960
- Testing
- EMR or ESD
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- Chinese University of Hong Kong
Rectal Neuroendocrine Tumor
Underwater Endoscopic Mucosal Resection Versus Endoscopic Submucosal Dissection for the Treatment of Small Rectal Neuroendocrine Tumors
Underwater endoscopic mucosal resection (UEMR) and endoscopic submucosal dissection (ESD) have both been reported to be two effective treatment methods for small rectal neuroendocrine tumor (NET).
- Trial name
- NCT07759960
- Testing
- UEMR procedure, ESD procedure
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Animal Model
Smart-gloves Hand Motion Tracking for Live Endoscopic Submucosal Dissection Training
Learning endoscopic submucosal dissection (ESD) is undertaken by experienced endoscopists in endoscopic mucosal resection and management of complications.
- Trial name
- EndoHandView (NCT06683326)
- Testing
- ROKOKO smart-glove
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Carol Davila University of Medicine and Pharmacy