Clinical trials: Endoscopic Submucosal Dissection
Colorectal Endoscopic Submucosal Dissection(ESD) Surgery
Endoscopic Ultrasound Guided Colorectal ESD and Traditional Colorectal ESD Surgery
A prospective randomized controlled study protocol between endoscopic ultrasound guided colorectal ESD and traditional colorectal ESD surgery
- Trial name
- NCT06076382
- Testing
- endoscopic ultrasound guided colorectal ESD surgery, the traditional colorectal ESD surgery
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Jilin University
VR, Virtual Reality Pain Distraction
Virtual Reality to Improve Patient Experience During Endoscopic Mucosal and Submucosal Resection
This study explores the feasibility of using Virtual Reality (VR) to manage pain and anxiety during Endoscopic Mucosal (EMR) and Submucosal Dissection (ESD).
- Conditions
- VR, Virtual Reality Pain Distraction, Endoscopic Submucosal Dissection, Endoscopic Mucosal Resection
- Trial name
- VREMRESD (NCT06766162)
- Testing
- Virtual reality pain distraction, Standard analgesia and sedation
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- King's College Hospital NHS Trust
Digestive System Diseases
Endoscopic Submucosal Dissection for Gastrointestinal Neoplasms
Endoscopic submucosal dissection (ESD) is a newly developed technique in the field of endoscopic treatment for GI neoplasms, because of its high rate of en bloc resection.
- Trial name
- NCT01378507
- Testing
- endoscopic submucosal dissection
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese PLA General Hospital
Patient Compliance
Effect of Questionnaires and Feedback on the Patient Compliance for Endoscopic Surveillance After ESD
Endoscopic submucosal dissection (ESD) is now considered the standard treatment for early gastrointestinal neoplasms. However, there is still a possibility of developing local recurrence or metachronous neoplasia after ESD.
- Trial name
- NCT06092281
- Testing
- Questionnaire, Questionnaire without compliance-related education
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastric Neoplasms
Clinical Impact of Second-look Endoscopy After Endoscopic Submucosal Dissection of Gastric Neoplasm
Gastroenterologists often follow up second look endoscopy after endoscopic submucosal dissection(ESD) of gastric neoplasms because they want to prevent bleeding of procedure sites.
- Trial name
- SLEGD (NCT02005809)
- Testing
- second look endoscopy
- Where
- South Korea
- Volunteers
- 268 people
- Sponsor
- Kosin University Gospel Hospital
Endoscopic Submucosal Dissection, Endoscopic Submucosal Dissection (ESD)
The Improvement Effect of Real-time Artificial Intelligence Assisted Identification of Bleeding Points on Hemostasis Efficiency in Endoscopic Submucosal Dissection
The goal of this clinical trial is to learn if an artificial intelligence (AI) system that identifies bleeding points in real time can help stop bleeding faster during endoscopic submucosal dissection (ESD) - a minimally invasive…
- Trial name
- NCT07495137
- Testing
- AI real-time assistance in endoscopic submucosal dissection (ESD) for bleeding spot identification and marking
- Volunteers
- 160 people
- Sponsor
- Qilu Hospital of Shandong University
Endoscopic Resection, Rectal Tumor
A Comparison of Endoscopic Synchronous Injection and Submucosal Dissection(ESISD) and Conventional Endoscopic Submucosal Dissection(CESD) for Granular Mixed Nodular Laterally Spreading Tumor in the Rectum (LST-G-M)
What is the study about? This study introduces and evaluates a new endoscopic technique called Endoscopic Synchronized Injection and Submucosal Dissection (ESISD).
- Trial name
- ESISD vs CESD (NCT07236827)
- Testing
- Endoscopic Synchronous Injection and Submucosal Dissection(ESISD), Conventional Endoscopic Submucosal Dissection(ESD)
- Volunteers
- 60 people
- Sponsor
- Taihe Hospital
Esophagus Cancer, Radiotherapy
A Clinical Study of Non-curative Resection Plus Radiotherapy After Endoscopic ESD for Superficial Esophageal Squamous Cell Carcinoma
The goal of observational study is to learn about the outcomes of the participants. The main questions it aims to answer are: 1.
- Conditions
- Esophagus Cancer, Radiotherapy, Endoscopic Mucosal Resection
- Trial name
- NCT06160557
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xiaomeng Zheng
Esophageal Cancer
Comparison of Esophagectomy and Chemoradiation for Patients With cN0-pT1b Stage Esophageal Squamous Cell Carcinoma
The ad-ESD trial is phase III randomized trial to compare adjuvant esophagectomy and chemoradiation for patients with clinical stage N0 and pathological stage T1b squamous cell carcinoma (after endoscopic submucosal dissection).
- Trial name
- NCT04135664
- Testing
- esophagectomy, chemoradiation, active surveillance
- Where
- 6 sites in China
- Volunteers
- 176 people
- Sponsor
- Shanghai Chest Hospital
Gastrointestinal Disease, Gastrointestinal Bleeding
Blood Pressure During ESD is Related With the Postoperative Bleeding
Endoscopic submucosal dissection(ESD) is a prominent minimally invasive operation technique for treating early gastrointestinal tumor.
- Trial name
- NCT03070665
- Testing
- Norepinephrine
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Shanghai Zhongshan Hospital
Early Gastric Cancer, Rectal Polyp
EndoscoPic Submucosal dIssection Using geL Versus glycerOl for Submucosal iNjection
The EPSILON study aims to comparatively evaluate the submucosal injection using ORISETM gel and glycerol during an ESD procedure in a specific population with superficial gastric and rectal (pre)neoplastic lesions.
- Trial name
- EPSILON (NCT04977401)
- Testing
- Endoscopic submucosal dissection, use of Orise Gel as lifting agent for endoscopic submucosal dissection, use of glycerol as lifting agent for endoscopic submucosal dissection
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 32 people
- Sponsor
- Erasme University Hospital
Esophageal Motility Disorders
Endolumenal Partial Myotomy for Esophageal Motility Disorders
Achalasia and esophageal spasm are primary esophageal motility disorders where the lower esophageal sphincter fails to relax in response to swallowing with no well understood underlying cause.
- Trial name
- NCT01302301
- Testing
- Per oral endolumenal myotomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Oregon Clinic
Endoscopic Surgical Procedures
Endoscopic Hand Suturing After Advanced Endoscopic Resections.
Endoscopic hand-suturing (EHS) has emerged as a promising modality in gastrointestinal (GI) endoscopic procedures. The available reports regarding its effectiveness in clinical practice are limited due to the relatively recent…
- Trial name
- NCT06622746
- Testing
- Endoscopic Hand Suturing
- Where
- Poland
- Volunteers
- 31 people
- Sponsor
- Jagiellonian University
Gastrointestinal Neoplasm
Traction vs. No Traction in Colonic ESD
The goal of this prospective, randomized, controlled trial conducted at Baylor St. Luke's Medical Center is to compare the effectiveness and clinical outcomes of using a traction device in colonic endoscopic submucosal dissection…
- Trial name
- NCT06159634
- Testing
- Endoscopic Submucosal Dissection, Traction Device
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Baylor College of Medicine
Esophageal Stricture, Esophageal Neoplasms
Tranilast Vs. Steroids to Prevent Esophageal Stricture (TAPES) After Endoscopic Resection for Superficial Neoplasms
The goal of this clinical trial is to learn if tranilast works to prevent esophageal stricture after circumferential endoscopic submucosal dissection (cESD) in adults.
- Trial name
- TAPES (NCT06643689)
- Testing
- Tranilast, Dexamethasone
- Where
- 3 sites in China
- Volunteers
- 394 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Endoscopic Submucosal Dissection, Colorectal Neoplasms
Early Feeding Versus Delayed Feeding After Colorectal Endoscopic Submucosal Dissection
Currently, there are no clear guidelines regarding the optimal timing for dietary restart after gastrointestinal endoscopic submucosal dissection (ESD).
- Trial name
- NCT06805123
- Testing
- Early feeding, Late feeding
- Where
- 5 sites in South Korea
- Volunteers
- 204 people
- Sponsor
- Pusan National University Hospital
Gastric Cancer Stage
Expanded Indications of Endoscopic Submucosal Dissection for Early Gastric Cancer in China
Background: The main treatment methods for early gastric cancer (EGC) include endoscopic submucosal dissection (ESD) and radical gastrectomy.
- Trial name
- NCT06869356
- Testing
- D2 gastrectomy
- Where
- China
- Volunteers
- 1,291 people
- Sponsor
- Beijing Friendship Hospital
Gastric Cancer
Efficacy and Safety of ESD for the Treatment of Superficial Gastric Neoplasms
Endoscopic submucosal dissection (ESD) is the technique that has replaced surgery in the treatment of early neoplastic lesions of the stomach (LNPS).
- Trial name
- NCT05930860
- Testing
- Endoscopic Submucosal Dissection
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Early Gastric Cancer or Gastric Adenoma
Pilot Trial on Efficacy of Single Dose Perioperative Intravenous Dexamethasone for Pain Relief After Endoscopic Submucosal Dissection
Besides major ESD-related complications, minor adverse events after ESD are also commonly noticed. Pain is one of minor ESD-related complications. .
- Trial name
- NCT02037399
- Testing
- intravenous dexamethasone, intravenous normal saline
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Gastric Cancer
Magnetic Anchoring Guided Endoscopic Submucosal Dissection for Early Gastric Caner
This study uses magnetic anchored guidance system to treat early gastric cancer by endoscopic mucosal dissection to test the advantages of magnetically anchored guidance system for surgical field exposure during endoscopic…
- Trial name
- MAGESD (NCT04327050)
- Testing
- Magnetic anchored guided endoscopic submucosal dissection
- Volunteers
- 30 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University