Clinical trials: Endoscopic Surgical Procedures
Lumbar Disc Herniation
Trial to Show Non-inferiority / Superiority of an Endoscopic Transforaminal Discectomy to Standard Microdiscectomy
This study compares an endoscopic transforaminal surgical technique for the treatment of a herniated disc to the standard microsurgical procedure. Clinical parameters as well as health economy will be assessed.
- Trial name
- TESCORT (NCT01622413)
- Testing
- joimax TESSYS, Microdiscectomy
- Where
- 3 sites in Austria, Germany
- Sponsor
- Joimax GmbH
Herniated Lumbar Disc
Postoperative Pain and Analgesic Use Following Lumbar Discectomy: A Comparative Study of Endoscopic Surgery and Open Surgery
The lifetime prevalence of lumbosacral radiculopathy is 3 to 5 percent. The most common cause is a lumbar disc herniation. In 10 to 20 percent of patients, medical treatment is insufficient, and surgery is recommended.
- Trial name
- DISCOPAIN (NCT07766031)
- Testing
- Endoscopic surgery, Open surgery
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Saint-Gregoire Private Hospital Center
Ectopic Pregnancy
Comparison of vNOTES and Laparoscopic Salpingectomy in the Surgical Treatment of Ectopic Pregnancy
This study compares vNOTES salpingectomy and laparoscopic salpingectomy in the treatment of ectopic pregnancy, focusing on outcomes such as operative time, postoperative pain, and recovery.
- Trial name
- vNOTES (NCT07057115)
- Testing
- vNOTES Salpingectomy Group., Laparoscopic Salpingectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Laryngeal Stenosis, Subglottic Stenosis
Study of Mitomycin-C Application in Laryngotracheal Stenosis
This is a randomized, prospective, double-blind, placebo-controlled clinical trial of the use of mitomycin-C topical application as an adjunctive treatment in the endoscopic surgical treatment of patients with laryngotracheal…
- Conditions
- Laryngeal Stenosis, Subglottic Stenosis, Tracheal Stenosis
- Trial name
- NCT01523275
- Testing
- Mitomycin -C, Saline application
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Francisco
Malignant Melanoma, Sinonasal Melanoma
Toripalimab Combined With Radiotherapy and Chemotherapy in the Treatment of SNMM After Endoscopic Surgery
Phase II, single-arm, prospective clinical study of Toripalimab(a PD-1 antibody) combined with radiotherapy and chemotherapy in the treatment of sinonasal malignant mucosal melanoma after endoscopic surgery.
- Trial name
- SNMM (NCT04879654)
- Testing
- endoscopic surgery
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Eye & ENT Hospital of Fudan University
PERCUTANEOUS CORONARY INTERVENTION, STENTS
The Surgery After Stenting (SAS) Registry
The SAS registry will include any patient with previous coronary stenting undergoing any type of surgery or operative endoscopic/endovascular procedure at the participating Centers.
- Conditions
- PERCUTANEOUS CORONARY INTERVENTION, STENTS, SURGERY
- Trial name
- SAS registry (NCT01997242)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Crohn's Disease
A Study of Guselkumab for the Treatment of Participants With Crohn's Disease After Surgical Resection
The purpose of this study is to evaluate the effectiveness of guselkumab treatment compared with placebo (an inactive substance with no medicine) in preventing recurrence of Crohn's disease in participants after surgery.
- Trial name
- PROGRESS (NCT05784129)
- Testing
- Guselkumab
- Where
- 11 sites in United States, Poland
- Volunteers
- 4 people
- Sponsor
- Janssen Research & Development, LLC
Bone Diseases
Open Versus Endoscopic Surgical Management Of Posterior Calcaneal Deformity.
Patients with posterior calcaneal deformity may presented by many clinical data associated with retrocalcaneal bursitis which occurs due to the deformity this clinical complaining include pain and swelling in the back of the…
- Trial name
- NCT03169465
- Testing
- open approach, endoscopic approach
- Volunteers
- 30 people
- Sponsor
- Assiut University
Gallstone Disease, Bile Duct Diseases
Gut Microbiome and Metabolome in Patients With Gallstone Disease After Surgical and Endoscopic Interventions
The goal of this longitudinal observational cohort study is to examine the changes in the composition and diversity of gut microbiome and systemic metabolome in patients with symptomatic gallbladder stones with or without…
- Trial name
- NCT05689255
- Where
- Singapore
- Volunteers
- 65 people
- Sponsor
- Changi General Hospital
Magnesium Sulfate, Remifentanil
Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension
This prospective, randomized controlled trial investigates the effect of four different anesthetic maintenance techniques on surgical field conditions, hemodynamic stability, and neuroprotection during functional endoscopic sinus…
- Conditions
- Magnesium Sulfate, Remifentanil, S 100beta, S100 Beta Protein, Human
- Trial name
- NCT07181564
- Testing
- Propofol / Remifentanil, Ketamine + Magnesium sulfate (drug combination), Sevoflurane and Remifentanil
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- University General Hospital of Patras
SARS-CoV 2, COVID
Increased Risk of SARS-CoronaVirus-2 (SARS-CoV-2) Infection Associated With Endoscopy (DECORE Study)
The aim of our study to compare the proportion of patients who develop SARS-CoV-2 disease in 3 groups: patients undergoing a abdominal ultrasound examination in a Specialty Center, patients undergoing endoscopic procedure in a…
- Trial name
- DECORE (NCT04401033)
- Testing
- Telephonic medical visit, Gastrointestinal endoscopy, Abdominal ultrasound
- Where
- Spain
- Volunteers
- 450 people
- Sponsor
- Hospital del Rio Hortega
Type 2 Diabetes Mellitus (T2DM)
Endoscopic Band Ligation for Type 2 Diabetes Mellitus (ENDOBAND-DM)
This is a pilot clinical study evaluating the safety and feasibility of Endoscopic Band Ligation (ENDOBAND-DM) applied to the second through fourth parts of the duodenum - from just distal to the ampulla of Vater to the ligament…
- Trial name
- ENDOBAND-DM (NCT07117721)
- Testing
- Endoscopic Band Ligation (ENDOBAND-DM)
- Volunteers
- 10 people
- Sponsor
- El Katib Hospital
Pancreatic Neoplasms, Pancreatic Fistula
Preoperative EUS Elastography for Pancreatic Texture and POPF Prediction After PD
This prospective study evaluates whether preoperative endoscopic ultrasound elastography (EUS-E) can predict pancreatic texture during surgery and risk of postoperative pancreatic fistula (POPF) in 100 patients undergoing…
- Trial name
- EUS-E (NCT07139236)
- Testing
- Preoperative Endoscopic Ultrasound Elastography (EUS Elastography)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Achalasia, Gastroparesis
Disposable Endoscope Platform in Third Space Endoscopic Procedures
This is a prospective, single-arm unblinded study performed at a single tertiary center in the United States. All subjects will receive standard medical care and no experimental interventions are going to be performed.
- Trial name
- NCT06738628
- Testing
- (Esophageal or Gastric) Per-Oral Endoscopic Myotomy
- Where
- United States
- Sponsor
- Baylor College of Medicine
Upper Gastrointestinal Endoscopy, Anesthesia
Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic Procedures
The investigators are comparing the efficacy of three different sedative agents in gastrointestinal endoscopic procedures.
- Trial name
- NCT07190612
- Testing
- Dexmedetomidine and propofol, Midazolam and propofol, ketamine and propofol
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Walled Off Pancreatic Necrosis (WON)
Rad Predictors for WON
This is a retrospective chart review study examining 1) demographic data such as age, sex, etiology of pancreatitis 2) clinical data including radiological characteristics of walled off pancreatic necrosis, walled off necrosis…
- Trial name
- NCT03801070
- Testing
- endoscopic drainage of walled off pancreatic necrosis
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Washington University School of Medicine
Intraoperative Bleeding
Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery
In endoscopic sinus surgery a clear surgical field of view is a very important aspect for good surgical outcome. This study is to evaluate the preoperative preparation to acquire best surgical field of view by comparing between…
- Trial name
- NCT05867342
- Testing
- Epinephrin, 1% lidocaine with epinephrin 1:100,000, Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Abdominal Adhesions
Natural Orifice Transgastric Endoscopic (NOTES) Transgastric Diagnostic Peritoneoscopy With Laparoscopic Assistance
The study will document being able to successfully perform transgastric diagnostic peritoneoscopy (laparoscopic visualization) using a small collection of study surgical tools.
- Trial name
- NOTES (NCT00962650)
- Testing
- Transgastric diagnostic peritoneoscopy with laparoscopic assistance
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Ethicon Endo-Surgery