Clinical trials: Endoscopic Therapy
Barretts Esophagus With Dysplasia
The Impact of Adjuvant Liquid Alginate on Endoscopic Ablation Therapy of Complicated Barrett's Esophagus
This study evaluates the addition of an alginate based solution to twice daily proton pump inhibitor therapy (PPI) in patients undergoing ablative therapy for dysplastic Barrett's esophagus.
- Trial name
- NCT03193216
- Testing
- Alginates
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Jaw Cysts
Treatment of Mandibular Bone Cyst by Navigation and Endoscopy
In this study, with the assistance of endoscopic technology and intraoperative navigation technology, the removal and curettage of large odontogenic jaw cyst occurred in the mandible were performed to reduce the rate of…
- Trial name
- NCT06567535
- Testing
- Navigation and endoscopy
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Colon Cancer, Colon Polyp
Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
The study will compare the use of cold snare, hot snare, cold EMR, and hot EMR for polyp resection. Although previous studies have compared two of the potential resection methods, no previous study has evaluated all four of the…
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma
- Trial name
- NCT03462706
- Testing
- Cold Snare, Hot Snare, Cold EMR
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Indiana University
Glue; Dependence
SAFETY AND EFFICACY OF ENDOSCOPIC CONVENTIONAL CYANOACRYLATE GLUE VS EUS-GUIDED COIL PLUS CYANOACRYLATE TECHNIQUE IN THE TREATMENT OF GASTRIC VARICES: A RANDOMIZED CONTROLLED TRIAL
To compare safety and efficacy of Endoscopic conventional technique (cyanoacrylate alone) to the EUS-guided injection technique (coil and cyanoacrylate) in the treatment of gastric varices.
- Trial name
- GLUE (NCT05038319)
- Testing
- EUS
- Where
- India
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Hypoxia, High Altitude
SJOV vs. HFNO for Hypoxia During Procedural Sedation at High Altitudes
This study aims to compare the effect of the use of supraglottic jet oxygenation and ventilation (SJOV) with high-flow nasal oxygen therapy (HFNO) on reducing the rate of hypoxia during gastrointestinal endoscopic procedures in…
- Trial name
- NCT05474287
- Testing
- SJOV, HFNO
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Patient Satisfaction, Anxiety State
Effect of Binaural Beats on Level of Anxiety and Toleration in Patients Undergoing Upper Gastrointestinal Endoscopy Without Sedation
To investigate the anxiolytic effects of binaural beat-embedded audio in patients undergoing sedation-free upper gastrointestinal endoscopy
- Conditions
- Patient Satisfaction, Anxiety State, Tolerance
- Trial name
- NCT06114524
- Testing
- binaural music
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Chronic Rhinosinusitis, Rhinosinusitis
Xylitol for Chronic Sinusitis
The purpose of this investigation is to conduct a randomized controlled trial within a subgroup of difficult-to-treat patients with CRS, evaluating the use of topical xylitol treatment concurrently with topical…
- Conditions
- Chronic Rhinosinusitis, Rhinosinusitis, Sinusitis, Drain Sinus
- Trial name
- NCT03229551
- Testing
- Xylitol, Saline
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Inflammatory Bowel Disease, Crohn Disease
Deep Endoscopic Remission Assessed by a Surrogate Biomarker in Patients With Inflammatory Bowel Disease
We hypothesize that the number of needed endoscopic procedure performed at IBD patients (adult and children), can be reduced by using an individualized algorithm of symptoms, blood and faecal biomarkers.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT01861288
- Where
- Denmark
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Craniosynostosis
Endoscopic Treatment for Isolated, Single Suture Craniosynostosis
This is a prospective study to evaluate outcomes in patients undergoing endoscopic craniectomy for isolated, single-suture craniosynostosis.
- Trial name
- NCT00769847
- Testing
- Endoscopic strip craniectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Barrett Esophagus
Impact of NBI on Patients Undergoing Endoscopic Eradication Therapy
This study tests the impact of narrow band imaging (NBI) on endoscopists' accurate detection of visible lesions and dysplasia in patients with Barrett's esophagus, as well as the effect of NBI on the choice of primary treatment…
- Trial name
- NCT03191604
- Testing
- Video intervention
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Gall Stones, Gall Stones (& [Calculus - Gall Bladder])
A Study on the Efficacy and Safety of Endoscopic Ultrasound-guided Gastro-/Duodeno-cholecystostomy for the Treatment of Gallstones.
Gallstones, as a common benign gallbladder disease worldwide, have a prevalence of approximately 6.1%. Although laparoscopic cholecystectomy (LC) is currently the mainstream treatment, its associated complications cannot be…
- Trial name
- NCT07522385
- Testing
- cholecystolithotomy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Obesity
Benefits of Endoscopic Bariatric Procedures
This 12-months long pilot study will include patients undergoing an endoscopic procedure (endoscopic sleeve gastroplasty [ESG] or transoral outlet reduction [TORe]) as clinically indicated, and subsequent follow up clinic visits…
- Trial name
- NCT05514288
- Testing
- Endobariatric procedure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Anemia, Colon Polyps
Same Day Bidirectional Endoscopies - Does the Sequence of Procedures or Choice of Insufflator Matter?
Upper endoscopies (Esophagogastroduodenoscopies-EGDs) as well as a lower endoscopies (Colonoscopies) are routinely performed by gastroenterologists to assess the lining of patients' upper and lower gastrointestinal tracts using a…
- Trial name
- NCT02635217
- Testing
- Carbon dioxide insufflation, room air insufflation, EGD (Esophagogastroduodenoscopy) before Colonoscopy
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen's University
Gastroduodenal Ulceration
Evaluation of Upper GI Ulceration Induced by PL2200 Versus Aspirin in At-Risk Subjects
This trial is a Phase 2, randomized, controlled study to compare the degree of mucosal injury after the oral administration of an investigational product, PL2200, and a marketed 325 mg immediate-release aspirin product.
- Trial name
- NCT01646814
- Testing
- PL2200, Aspirin tablets
- Where
- 10 sites in United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- PLx Pharma
Gastric Dysplasia
Endoscopic Submucosal Dissection Using a Thulium Laser
We aim to evaluate safety and feasibility of a thulium laser system in performing endoscopic submucosal dissection of gastric neoplasia.
- Trial name
- NCT01753544
- Where
- South Korea
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Dental Pulp Cavity, Root Canal Treatment
Endoscopic Treatment During Endodontic Procedures
The objectives of this Phase I study is to evaluate the safety and effectiveness of the endoscopic endodontic equipment device for root canal assistance treatment as well as to evaluate the ease of use of this device, by a…
- Conditions
- Dental Pulp Cavity, Root Canal Treatment, Endoscopy
- Trial name
- NCT01192607
- Testing
- Endoscopic treatment during root canal treatment
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Painful Bladder Syndrome (PBS), Interstitial Cystitis
Submucosal Intravesical Injection of Platelet-rich Plasma in the Treatment of Painful Bladder Syndrome
Interstitial cystitis/painful bladder syndrome (IC/PBS) is characterized by a constellation of bladder symptoms, including urinary frequency, urgency, nocturia, and pelvic pain.
- Trial name
- PRP (NCT06209008)
- Testing
- Intravesical injection of Platlet Rich Plasma (PRP)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Helicobacter Pylori Infections, Atrophic Gastritis
Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for Prevention of Gastric Cancer Mortality
Currently no ideal preventive modalities are available for reducing gastric-cancer caused mortality in organized population-based application.
- Conditions
- Helicobacter Pylori Infections, Atrophic Gastritis, Gastric Cancer
- Trial name
- GISTAR (NCT02047994)
- Testing
- Triple therapy
- Where
- Latvia
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Chronic Rhinosinusitis, Nasal Polyps
Adjunctive Treatment for Chronic Rhinosinusitis With Nasal Polyposis
This is a research study to find out if an off-label use of carboxymethylcellulose foam (CMC), an absorbable nasal packing, combined with triamcinolone acetonide, a steroid, is more comfortable postoperatively for participants…
- Trial name
- NCT03607175
- Testing
- Triamcinolone-impregnated CMC foam, Propel Stent
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marina Boruk
Adenoma Colon
Efficacy of Artificial Intelligence-assisted Colonic Polyp Detection System
This is a randomized controlled multicenter clinical trial of computer-aided detection (CADe) system for the adjuvant diagnosis of intestinal polyps/adenomas ever conducted in a Chinese population.
- Trial name
- NCT05941689
- Testing
- AI-assisted colonoscopy
- Where
- 2 sites in China
- Volunteers
- 1,906 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University