Clinical trials: Endoscopic Ultrasound (EUS)
Pancreatic Mass
Comparing the Diagnostic Efficacy of Different Suction Techniques for EUS-FNB of Pancreatic Solid Lesions
There are many factors that can affect the diagnostic yield of EUS-FNA, including lesion factors, the endoscoist experience, the needle size, the number of needle passes, and the suction technique.
- Trial name
- NCT04100941
- Testing
- standard suction, slow pull, wet suction
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Abdomen, Mediastinum
Endoscopic Ultrasound (EUS) Artificial Intelligence Model for Normal Mediastinal and Abdominal Strictures Assessment
Therefore, a high number of procedures is necessary to achieve EUS competency, but interobserver agreement still varies widely. Artificial intelligence (AI) aided recognition of anatomical structures may improve the training…
- Conditions
- Abdomen, Mediastinum, Anatomic Abnormality, Strictures
- Trial name
- NCT05151939
- Testing
- Identification or discharge visualization of mediastinal and abdominal organ/anatomic strictures through Endoscopic ultrasound (EUS) videos by an expert endoscopist, Recognition of mediastinal and abdominal organ/anatomic strictures through Endoscopic ultrasound (EUS) videos using artificial intelligence (AI)
- Where
- Ecuador
- Volunteers
- 60 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Obstructive Jaundice, Bilio-pancreatic Tumor
Endoscopic Ultrasound Evaluation of the Common Bile Duct in Patients With Obstructive Jaundice Due to Bilio-pancreatic Malignancies (ECCO Trial)
To assess the size of the common bile duct in a large cohort of patients with jaundice following a malignant tumor of the head of the pancreas or the distal bile duct receiving a diagnostic EA for biopsy and / or for evaluation…
- Trial name
- ECCO (NCT05155475)
- Testing
- Ultrasound endoscopy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Neoplasms, Cystic, Mucinous, and Serous
Endoscopic Ultrasound-guided Ethanol Injection of Pancreatic Cystic Neoplasms
Cystic tumors of the pancreas are fluid-filled growths. They are often treated by surgical removal. A safe and effective non-surgical treatment is desirable.
- Trial name
- NCT02158039
- Testing
- Ethanol, Lidocaine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Mayo Clinic
Acute Necrotizing Pancreatitis, Walled Off Necrosis
Plastic Stents vs. NAGI Bi-flanged Metal Stent for Endoscopic Ultrasound Guided Drainage of Walled-off Necrosis
Introduction: Walled off necrosis (WON) is defined as a well circumscribed pancreatic and/or peri pancreatic necrosis containing a variable amount of necrotic tissue.
- Trial name
- NCT04479228
- Testing
- Endosonography guided transmural drainage
- Volunteers
- 80 people
- Sponsor
- Asian Institute of Gastroenterology, India
Lung Cancer
EUS-B-FNA in the Diagnosis of Malignant Parenchymal Lung Lesions
The aim of this study is to evaluate the diagnostic accuracy, safety and tolerability, predictors of success of EUS-B-FNA in the diagnosis of malignant parenchymal lung lesions.
- Trial name
- NCT03983005
- Testing
- EUS-B-FNA
- Where
- 4 sites in Italy
- Volunteers
- 107 people
- Sponsor
- University of Milan
Pancreas Cyst
DNA-mutation Analysis in Cyst Fluid of Suspected Intraductal Papillary Mucinous Neoplasia of the Pancreas
Diagnostic tools are needed to identify mucinous cysts for further evaluation or follow-up respectively to identify cysts with HGD or invasive cancer at an early stage for surgical resection.
- Trial name
- NCT03820531
- Testing
- Next Generation Sequencing, CEA and lipase, Cytology
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Theresienkrankenhaus und St. Hedwig-Klinik GmbH
Liver Fibroses
The EUS ShearWave Elastography Liver Fibrosis Study
The study objective is to demonstrate the clinical performance of ShearWave Elastography (SWE) in Endoscopic Ultrasound (EUS) when compared to FibroScan for evaluation of liver fibrosis.
- Trial name
- NCT04115046
- Testing
- ShearWave Elastography (SWE) in Endoscopic Ultrasound (EUS), FibroScan, ALOKA ARIETTA 850 -
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Olympus Corporation of the Americas
Fine Needle Aspiration, Pancreatic Mass
EUS FNB Versus FNA With On-Site Cytopathology in Solid Pancreatic Masses
The objective of this paired cohort study is to evaluate the diagnostic accuracy of Endoscopic Ultrasound-fine needle aspiration (EUS-FNA) with rapid onsite evaluation (ROSE) compared to EUS-fine needle biopsy (EUS-FNB) without…
- Trial name
- NCT03485924
- Testing
- EUS-FNA with ROSE, EUS-FNB without ROSE
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Non Small Cell Lung
Clinical Impact of EUS in Staging NSCLC
The goal of this prospective study is to determine the clinical and economic impact of endoscopic ultrasound (EUS) in staging NSCLC.
- Trial name
- NCT00577746
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Indiana University
Unresectable Locally Advanced Pancreatic Carcinoma
Safety and Efficacy of NRT6008 Administered in Combination With Chemotherapy in Patients With Unresectable Locally Advanced Pancreatic Carcinoma (LAPC)
This is a phase Ib, open-label study to evaluate safety and efficacy of NRT6008 in combination with standard-of-care chemotherapy in patients with unresectable Locally Advanced Pancreatic Carcinoma (LAPC).
- Trial name
- NCT07555587
- Testing
- NRT6008 Injection, Systematic chemotherapy
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- NRT MedTech Australia Pty Ltd
Insulinoma; Pancreas
Safety and Efficacy of EUS-RFA in Pancreatic Insulinoma
Transcutaneous and EUS-guided radiofrequency ablation are both modern modalities to apply in the managemnet of various malignancies.
- Trial name
- EUSRFAINSU (NCT07585032)
- Testing
- EUS-RFA
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Sahlgrenska University Hospital
Anxiety, Pancreatic Cancer
Graphic Novel for Patients Undergoing EUS-FNB
Endoscopy with endoscopic ultrasound (EUS) is a primary technique for diagnosing and treating severe pancreatic disorders. However, the procedure can cause fear and anxiety in patients, especially when a biopsy is involved.
- Conditions
- Anxiety, Pancreatic Cancer, Pancreatic Cystic Lesions, Stress
- Trial name
- NCT06268106
- Testing
- Graphic novel visualization
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
Endoscopic Ultrasound (EUS), Solid Pancreatic Lesion
An Artificial Intelligence System for Multimodal, Multi-class Diagnosing Solid Pancreatic Lesions Based on Endoscopic Ultrasound
The aim of this study is to validate an artificial intelligence system named iEUS-SPL(intelligent endoscopic ultrasound system-solid pancreatic lesion) for detecting and multimodal, multi-class diagnosing solid pancreatic lesions…
- Trial name
- NCT07381192
- Testing
- iEUS-SPL(intelligent endoscopic ultrasound system-pancreatic solid lesion)
- Where
- China
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Pancreatitis Acute Biliary
Early Endoscopic Ultrasound - Based Sphincterotomy or Conservative Treatment in Severe Biliary Pancreatitis
The primary purpose of this trial is to determine whether an early Early Endoscopic Ultrasound (EUS) immediately followed by an endoscopic sphincterotomy (ES) in case of bile duct stones may improve outcomes in patients with…
- Trial name
- EEPAB2 (NCT00987428)
- Testing
- ultrasonography with or not sphincterotomy, Usual procedure
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pancreatic Cancer, Endoscopic Ultrasound
Ex-vivo Ultrasound Guided Radiofrequency Ablation on Pancreatic Solid Lesions
The study investigates the feasibility and the efficacy to treat pancreatic solid lesions as pancreatic adenocarcinomas (PDAC) and neuroendocrine tumors (NET) with ex-vivo radiofrequency ablation (RFA) under ultrasound (US)…
- Conditions
- Pancreatic Cancer, Endoscopic Ultrasound, Radiofrequency Ablation
- Trial name
- NCT06371716
- Testing
- ex-vivo RFA under US control at 10 Watts (W) of power in 3 differents arms of lesions, ex-vivo RFA under US control at 30 Watts (W) of power in 3 differents arms of lesions, ex-vivo RFA under US control at 50 Watts (W) of power in 3 differents arms of lesions
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- IRCCS San Raffaele
Throat Pain After EUS Insertion
A Comparison of Endoscopic Ultrasound Insertion Methods
Endoscopic ultrasonography (EUS) is an essential technique required in diagnosis of pancreatobiliary diseases. In previous studies, 6% of patients who undergone EUS had significant throat pain.
- Trial name
- NCT02924948
- Testing
- Balloon inflation
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Acute Biliary Pancreatitis
Early EUS in Acute Biliary Pancreatitis
Acute biliary pancreatitis (ABP) is a potentially life-threatening condition caused by common bile duct (CBD) stones or sludge, which requires prompt diagnosis and treatment by endoscopic removal of the material.
- Trial name
- NCT02430285
- Testing
- Endoscopic Ultrasound, Olympus 180 series echoendoscope
- Where
- Italy
- Volunteers
- 181 people
- Sponsor
- Istituto Clinico Humanitas
Esophageal Cancer
Relationship Between Endoscopic Ultrasound Staging and Degree of Stricture in Esophageal Cancer
The primary objective of this study is to document all cases of EUS in patients with esophageal cancer and determine if the inability to advance the gastroscope beyond the tumor correlates with locally advanced disease stage at…
- Trial name
- ESOCA (NCT02372929)
- Testing
- Endoscopic Ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- AdventHealth
Endoscopic Ultrasound
Effectiveness of an Ai-based Endoscopic Ultrasound Navigation System in the Training of Endoscopic Ultrasonics
In the early stage, the investigators successfully constructed an artificial intelligence model-based ultrasonic endoscopy-assisted film reading system and named the modified system biliopancreatic Master.
- Trial name
- NCT05421520
- Testing
- Artificial intelligence assisted system
- Where
- 2 sites in China
- Volunteers
- 12 people
- Sponsor
- Renmin Hospital of Wuhan University