Clinical trials: Endoscopy
Crohn Disease, Genetic Predisposition
The Biologic Onset of Crohn's Disease: A Screening Study in First Degree Relatives
Pursuing very early diagnosis is standard of care for several diseases including colon cancer, diabetes and liver disease where an early and aggressive diagnostic and therapeutic approach has been shown to change their natural…
- Conditions
- Crohn Disease, Genetic Predisposition, IBD
- Trial name
- NCT03291743
- Testing
- Capsule endoscopy
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Mitochondrial DNA Mutation, Endoscopy
Multimodal Imaging Based on Pathological and Genomic Characteristics
Mitochondrial DNA mutations in normal gastric tissue, early gastric cancer and advanced gastric cancer were identified by single cell sequencing, and the origin of gastric stem cells was traced and new molecular markers were…
- Trial name
- NCT05196243
- Testing
- Patients diagnosed as gastrointestinal mucosal lesions
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Jaw Cysts
Treatment of Mandibular Bone Cyst by Navigation and Endoscopy
In this study, with the assistance of endoscopic technology and intraoperative navigation technology, the removal and curettage of large odontogenic jaw cyst occurred in the mandible were performed to reduce the rate of…
- Trial name
- NCT06567535
- Testing
- Navigation and endoscopy
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
GERD
ANTI REFLUX MUCOSAL ABLATION THERAPHY (ARMA)
OBJECTIVES To study the safety and efficacy of Endoscopic Anti Reflux Mucosal Ablation (ARMA) procedure for the treatment of proton pump inhibitor (PPI) dependent gastro-esophageal reflux disease (GERD) DESIGN OF THE Prospective…
- Trial name
- ARMA (NCT04243668)
- Testing
- ANTI REFLUX MUCOSAL ABLATION THERAPHY (ARMA)
- Where
- India
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Postoperative Pain
Effectiveness of Bilateral Endoscopic Sphenopalatine Ganglion Block on Postoperative Pain After Septoplasty
The aim of this clinical study will investigate the efficacy of sphenopalatine ganglion block in the treatment of postoperative pain.it will also be learnt whether it reduces the consumption of analgesics in postoperative…
- Trial name
- NCT06695624
- Testing
- Sphenopalatine Ganglion Block
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Paranasal Sinuses
Variants of Paranasal Sinuses in Nepali Population
The variants of paranasal sinuses (PNS)and nasal cavity are of clinical importance since some variants are susceptible to recurrent infection.
- Trial name
- NCT06683859
- Where
- Nepal
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Grande International Hospital, Nepal
Pancreatic Cysts
Prevalence of Pancreatic Cysts During Routine Endoscopic Ultra Sound
The investigators are interested in performing a detailed examination of the pancreas via EUS (Endoscopic Ultra Sound)for patients referred for a non-pancreatic condition.
- Trial name
- NCT01624363
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Indiana University
Gastrointestinal Neoplasms
Evaluation of Neoplasia With Artificial Intelligence in Gastrointestinal Endoscopy
This study aims to validate and evaluate AI algorithms for detection and characterization of early GI neoplasia.
- Trial name
- NEW-AGE (NCT04937647)
- Testing
- collection of endoscopic images and videos
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
POEMS Syndrome, Hemostatic Disorder
To Evaluate Efficacy of Red Dichromatic Imaging (RDI) in Achieving Hemostasis During POEM Using GF 1500 UGI Scope
Peroral endoscopic myotomy (POEM) is a novel endoscopic technique for the treatment of achalasia and other esophageal motility disorders. Initially, it was introduced to the world by Inoue et al.
- Trial name
- RDIH-01 (NCT05476458)
- Testing
- White Light Imaging, Red Light Imaging
- Where
- 2 sites in India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Gastrointestinal Disease
Deep Learning Algorithm for the Diagnosis of Gastrointestinal Diseases
The purpose of this study is to develop and validate a deep learning algorithm for the diagnosis of gastrointestinal diseases. Then, evaluate the accuracy this new artificial intelligence(AI) assisted recognition system in clinic…
- Trial name
- NCT04222439
- Testing
- AI for the Diagnosis of Gastrointestinal Diseases
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Shandong University
Colonic Polyps, Esophageal Diseases
Confocal Probe-based Endoscopic Imaging, Colorectal Cancer, Gastrointestinal (GI) Pathologies
The recently developed endoscopic Confocal probe microscopy system allows imaging of surface epithelium during ongoing endoscopy (upper and lower) with the potential of immediate diagnosis of various GI pre-malignant and…
- Trial name
- ASGE-FNDT-1 (NCT00874263)
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Glue; Dependence
SAFETY AND EFFICACY OF ENDOSCOPIC CONVENTIONAL CYANOACRYLATE GLUE VS EUS-GUIDED COIL PLUS CYANOACRYLATE TECHNIQUE IN THE TREATMENT OF GASTRIC VARICES: A RANDOMIZED CONTROLLED TRIAL
To compare safety and efficacy of Endoscopic conventional technique (cyanoacrylate alone) to the EUS-guided injection technique (coil and cyanoacrylate) in the treatment of gastric varices.
- Trial name
- GLUE (NCT05038319)
- Testing
- EUS
- Where
- India
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Gastric Transit Time
Study to Evaluate the Efficacy of Oral Dissolving Metoclopramide Before Video Capsule Endoscopy
Summary: This study investigates the use of oral dissolving metoclopramide during standard video capsule endoscopy. Metoclopramide is a pro -motility agent, that is, this medication helps with movement through the stomach and…
- Trial name
- NCT01631994
- Testing
- metoclopramide
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Gastrostomy, Ventilatory Failure
Concomitant Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy
The goal of this research study is to assess the FDA approved technique for inserting a feeding tube (gastrostomy) along with a breathing tube (tracheostomy) for patients that cannot breathe or eat on their own in the ICU…
- Conditions
- Gastrostomy, Ventilatory Failure, Respiratory Failure
- Trial name
- TPUG (NCT05955534)
- Testing
- TPUG, PEG, PRG
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Middle Ear Disease
The Effect of Tranexamic Acid in Endoscopic and Microscopic Ear Surgery Cases on Surgeon Satisfaction
By using tranexamic acid, an antifibrinolytic drug, the aim is to prevent the restriction of the field of view of the surgical field due to bleeding in middle ear microscopic and endoscopic surgery operations in which controlled…
- Trial name
- NCT06434636
- Testing
- Transamine 10% IV/IM Solution for Injection, %0.9 Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Obesity
Prospective Multicenter Study With the Endomina® Triangulation Platform
This registry is designed to further assess on a larger scale safety and efficacy of the endomina® device and tissue apposition accessories (TAPES) when used in the frame of "real life" routine clinical practice
- Trial name
- PRETTi (NCT05677464)
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Endo Tools Therapeutics S.A.
Competence in Propofol Sedation for Endoscopy
Assessment of NAPS Performance.
To measure competencies in propofol sedation for endoscopic procedures (NAPS)through development, test and validation of a reliable assessment tool in a simulator setting.
- Trial name
- NAPSAT (NCT01768143)
- Testing
- unexperienced endoscopy nurses, Experienced endoscopy nurses
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Healthy, Barrett's Esophagus
Pilot Study to Image the Esophagus Using a SECM Tethered Endoscopic Capsule
The goal of this research is to test the imaging quality of the modified, larger diameter, tethered Spectrally Encoded Confocal Microscopy (SECM) capsule in healthy subjects, subjects with Barrett's Esophagus (BE), and subjects…
- Conditions
- Healthy, Barrett's Esophagus, Gastric Acid Reflux
- Trial name
- SECM (NCT02445014)
- Testing
- MGH SECM Imaging Capsule
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Endoscopy, Digestive System, GLP1-R-related Disease
Evaluate the Detection of Retained Gastric Contents and Assess Safety Using the Flower Capsule Endoscopy in Healthy Individuals and GLP-1 Receptor Agonist Users
Clinical Study Overview Feasibility Study Plan (Study 1: Healthy Participants) Study 1- Confirming Flower capsule performance characteristics in detection of retained gastric contents greater than 1.5mL/kg in Healthy volunteers…
- Trial name
- NCT06927401
- Testing
- Flower
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Colorectal Adenoma, Colorectal Polyp
Validation of the Global Polypectomy Assessment Tool (GPAT)
Colorectal polypectomy is offten incompletely performed with high variability between endoscopists, resulting in interval cancer or repeated procedures.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colo-rectal Cancer
- Trial name
- GPAT (NCT05877456)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent