Clinical trials: Endoscopy
Malignant Distal Biliary Obstruction
EUS-Guided Biliary Drainage in Patients With Inoperable Malignant Distal Biliary Obstruction and Failed ERCP: a Prospective Feasibility Multicenter Trial
This research is being done to study the safety and feasibility of recruiting patients eligible for EUS-guided biliary drainage (EGBD). Our goal is to prospectively study safety and effectiveness of this procedure.
- Trial name
- NCT01889953
- Testing
- EUS-guided biliary drainage
- Where
- 13 sites in United States, India and 3 more
- Volunteers
- 96 people
- Sponsor
- Johns Hopkins University
Thyroid, Acute Pain
Ketamine in Robot-assisted Thyroidectomy
In this prospective double-blinded study, The investigators compared acute postoperative pain and rescue analgesic demand during postoperative period after robot thyroidectomy between ketamine and placebo groups.
- Conditions
- Thyroid, Acute Pain, Chronic Pain
- Trial name
- KEThyRobot (NCT01997801)
- Testing
- Ketamine infusion, NS infusion
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Gastrointestinal Disease, Endoscopy
A Multicentric Validation Study on the Accuracy of Artificial Intelligence Assisted System in Clinical Application of Digestive Endoscopy
This is an artificial intelligence-based optical artificial intelligence assisted system that can assist endoscopists in improving the quality of endoscopy.
- Conditions
- Gastrointestinal Disease, Endoscopy, Artificial Intelligence
- Trial name
- NCT04232462
- Testing
- Endoscopists refer to AI for diagnosis
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Renmin Hospital of Wuhan University
Barrett's Esophagus, GERD
Study of Endoscopic Barrett's Esophagus Diagnosis
Barrett's esophagus (BE) is a condition that often occurs in patients who have had GERD for a long time. The researchers are interested in BE because it can sometimes become a cancer in the esophagus.
- Trial name
- NCT00591461
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Oregon Health and Science University
Neurogenic Dysphagia
Functional Endoscopy in Neurogenic Dysphagia
The esophago-gastro-duodenoscopy is an endoscopic examination technique of the upper GI-tract which was founded by the German surgeon Johann Freiherr von Mikuliicz-Radecki at the end of 19th century.
- Trial name
- NCT01995929
- Testing
- transnasal functional endoscopy
- Where
- 2 sites in Germany
- Volunteers
- 62 people
- Sponsor
- University Hospital Muenster
Abdominal Pain
EUS vs EGD in Emergency Room Patients Referred for EGD
Emergency room patients referred for esophago-gastro-duodenoscopy (EGD) often have many possible causes for their symptoms. These patients inevitably undergo further testing if EGD is inconclusive, which adds costs and prolongs…
- Trial name
- EUSvsEGD (NCT04408872)
- Testing
- Esophago-gastro-duodenoscopy (EGD), Endoscopic ultrasound (EUS)
- Where
- 2 sites in Canada
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lumbosacral Spinal Stenosis
Irrigation Endoscopic Decompressive Laminotomy
The classic laminectomy for surgical treatment of spinal stenosis has considerable morbidity .This is further magnified by the disease being more common in elderly with associated medical comorbidities and being usually global…
- Trial name
- NCT01991912
- Testing
- open lumbar decompression
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Colonic Diseases
Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) Preparation and Procedure
The purpose of this study is to compare two preparation and procedure in order to develop the most optimal capsule procedure in regards to colon cleansing level and capsule excretion rate.
- Trial name
- NCT00885339
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG
Pancreatic Collection
Lumen Apposing Metal Stents With and Without a Double Pigtail Stent in Pancreatic Collections
The study evaluates the security of LAMS with ando without a coaxial double pigtail plastic stent in the management of pancreatic fuid collections.
- Trial name
- NCT03282539
- Testing
- LAMS, LAMS + pigtail
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- Hospital Universitari de Bellvitge
Inflammatory Bowel Diseases
Endoscopic Scoring System Utilization in Inflammatory Bowel Disease
Inflammatory bowel diseases comprise two distinctive entities: Crohn's disease and ulcerative colitis. During the last decade, endoscopic assessment of inflammation has become relevant since it is a prognostic factor.
- Trial name
- NCT05576402
- Testing
- colonoscopy
- Where
- Argentina
- Volunteers
- 1,500 people
- Sponsor
- Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno
Trigger Finger
Endoscopic Trigger Finger Release
The purpose of this study is to compare recovery, scar, and patient satisfaction after retrograde endoscopic trigger finger release versus the standard open surgical treatment.
- Trial name
- NCT03883477
- Testing
- Endoscopic Release, Standard Open Release
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Tendinopathy
A Comparison of Endoscopic Surgery and Exercise Therapy in Patients With Longstanding Achilles Tendinopathy
Exercise is a preferred treatment modality for mid-portion achilles tendinopathy. Despite this, as many as 44 % of achilles tendinopathy patients do not respond to exercise treatment.
- Trial name
- NCT03025412
- Testing
- endoscopic surgery, physiotherapy and exercise
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Norwegian University of Science and Technology
Colon Polyp
The Colon Endoscopic Bubble Scale (CEBuS); Validation Study
Colonoscopy is currently accepted as the gold standard in screening, surveillance and prevention for colorectal cancer (CRC), and therefore, its quality is a major priority.
- Trial name
- CEBuS (NCT04378088)
- Testing
- Validation of CEBuS
- Where
- Portugal
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Polyp, Colonic, Bleeding
Clip Placement Following Colonic Endoscopic Mucosal Resection (EMR)
Study design: A national, multi-center, patient-blinded, randomized clinical trial. Study population: Patients undergoing EMR with a moderate to severe risk (right sided colon, ≥2cm) of developing Delayed Bleeding (DB).
- Trial name
- CLIPPER (NCT03309683)
- Testing
- Olympus Quick Clip Pro - Single Use Repositionable Clips
- Where
- 2 sites in Netherlands
- Volunteers
- 356 people
- Sponsor
- Radboud University Medical Center
Obesity
The ACE Follow-up Study
The Articulating Circular Endoscopic (ACE) Stapler is an investigational system using endoscopic guidance to trans-orally place plications in the stomach in obese subjects to reduce volume and expansion of the fundus and greater…
- Trial name
- NCT01429194
- Testing
- ACE Stapler
- Where
- 6 sites in Argentina, Canada and 2 more
- Volunteers
- 69 people
- Sponsor
- Boston Scientific Corporation
Dysphagia, Respiratory Complications
Trial- Dysphagia From ETT or GI Endoscopy
The purpose of this study is to conduct a randomized clinical trial to compare the incidence of dysphagia in patients receiving general anesthesia with and without an endotracheal tube for Upper gastrointestinal endoscopy.
- Trial name
- NCT02460055
- Testing
- endotracheal tube, propofol, Fentanyl
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Gastroesophageal Reflux Disease (GERD)
A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric Patients
The purpose of the study is to access the effectiveness and safety of oral rabeprazole in the treatment of acid-related disorders in pediatric patients, focusing specifically on the manifestation of GERD (symptomatic and erosive…
- Trial name
- NCT00787891
- Testing
- rabeprazole
- Volunteers
- 127 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Obesity
ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss
The purpose of this clinical research trial is to study safety and effectiveness of the TransPyloric Shuttle System (TPSS) for weight reduction in patients who are considered medically obese.
- Trial name
- NCT02518685
- Testing
- TransPyloric Shuttle, Lifestyle Counseling
- Where
- 9 sites in United States
- Volunteers
- 302 people
- Sponsor
- BaroNova, Inc.
Walled Off Pancreatic Necrosis
AXIOS Lumen Apposing Metal Stent for Walled Off Necrosis Drainage IDE Study
To demonstrate safety and effectiveness of lumen-apposing metal stents for resolution of walled off pancreatic necrosis (WONs) in patients with WONs with solid component >30%.
- Trial name
- NCT03525808
- Testing
- AXIOS
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Boston Scientific Corporation
Evaluation,Efficacy,Safety
Evaluation of the Efficacy and Safety of Magnetically-controlled Capsule Gastroscopy for Postoperative Assessment in Elderly Patients and Patients With Underlying Diseases
The objective of this prospective, observational, controlled clinical study is to use magnetically-controlled capsule gastroscopy for postoperative assessment in elderly patients and patients with underlying diseases, to evaluate…
- Trial name
- NCT06029608
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine